Anti-proliferative action of endogenous dehydroepiandrosterone metabolites on human cancer cell lines

Steroids

Volumn 68, Issue 1, 2003, Pages 73-83

  Yoshida, Shigemasa ^a   Honda, Akira ^a,b   Matsuzaki, Yasushi ^a   Fukushima, Sugano ^a   Tanaka, Naomi ^a   Takagiwa, Aya ^c   Fujimoto, Yoshinori ^c   Miyazaki, Hiroshi ^d   Salen, Gerald ^e,f  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Ibaraki Prefectural Institute of Public Health   (Japan)

^c TOKYO INSTITUTE OF TECHNOLOGY   (Japan)

^d NIIGATA UNIVERSITY OF PHARMACY AND APPLIED LIFE SCIENCES   (Japan)

^e RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

3 Hydroxy 3 methylglutaryl CoA reductase; Anti proliferation; Cancer; Dehydroepiandrosterone; Glucose 6 phosphate dehydrogenase; Metabolites

Indexed keywords

7 OXOHYDROXYPRASTERONE; 7ALPHA HYDROXYPRASTERONE; 7BETA HYDROXYPRASTERONE; ANDROSTERONE; DEOXYRIBONUCLEOSIDE; EPIANDROSTERONE; ETIOCHOLANOLONE; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE; MEVALONOLACTONE; PRASTERONE; PRASTERONE SULFATE; PREGNENOLONE; RIBONUCLEOSIDE; STEROID; UNCLASSIFIED DRUG; 7 HYDROXYDEHYDROEPIANDROSTERONE; 7-HYDROXYDEHYDROEPIANDROSTERONE; DRUG DERIVATIVE;

ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL GROWTH; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFECT; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; METASTASIS; CELL CULTURE; CELL DIVISION; DOSE RESPONSE; KINETICS; METABOLISM; NEOPLASM; OXIDATION REDUCTION REACTION; PATHOLOGY;

CELL DIVISION; DEHYDROEPIANDROSTERONE; DEHYDROEPIANDROSTERONE SULFATE; DOSE-RESPONSE RELATIONSHIP, DRUG; ETIOCHOLANOLONE; GLUCOSEPHOSPHATE DEHYDROGENASE; HUMANS; HYDROXYMETHYLGLUTARYL COA REDUCTASES; KINETICS; NEOPLASMS; OXIDATION-REDUCTION; RIBONUCLEOSIDES; TUMOR CELLS, CULTURED;

EID: 0037211772     PISSN: 0039128X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0039-128X(02)00117-4     Document Type: Article

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