Antagonist efficacy in MORS196L mutant is affected by the interaction between transmembrane domains of the opioid receptor

Journal of Pharmacology and Experimental Therapeutics

Volumn 313, Issue 1, 2005, Pages 216-226

  Claude Geppert, Patricia A ^a   Liu, Jiahui ^a   Solberg, Jonathan ^a   Erickson Herbrandson, Laurie J ^a   Loh, Horace H ^a   Law, Ping Yee ^a  

^a UNIVERSITY OF MINNESOTA MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DELTA OPIATE RECEPTOR; DEXTRO PHENYLALANYLCYSTEINYLTYROSYL DEXTRO TRYPTOPHYLORNITHYLTHREONYLPENICILLAMINYLTHREONINAMIDE 2,7 DISULFIDE; ENKEPHALIN; ENKEPHALIN[2 DEXTRO ALANINE 4 METHYLPHENYLALANINE 5 GLYCINE]; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; LEUCINE; MU OPIATE RECEPTOR; NALORPHINE; NALOXONE; NALTREXONE; NALTRIBEN; OPIATE ANTAGONIST; OPIATE RECEPTOR; SERINE; TYROSINE 1,2,3,4 TETRAHYDROISOQUINOLINE 3 CARBOXYLIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CHIMERA; CONTROLLED STUDY; DRUG EFFICACY; GENE MUTATION; HUMAN; HUMAN CELL; MOLECULAR MODEL; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION;

ANIMALS; CYCLIC AMP; DIPRENORPHINE; ELECTROPHYSIOLOGY; MUTAGENESIS, SITE-DIRECTED; MUTATION; NALOXONE; NALTREXONE; NARCOTIC ANTAGONISTS; OOCYTES; PATCH-CLAMP TECHNIQUES; RADIOLIGAND ASSAY; RECEPTORS, OPIOID; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, MU; RECOMBINANT FUSION PROTEINS; RNA, COMPLEMENTARY; XENOPUS;

EID: 15744388079     PISSN: 00223565     EISSN: None     Source Type: Journal    
DOI: 10.1124/jpet.104.076505     Document Type: Article

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