δ-Opioids stimulate inositol 1,4,5-trisphosphate formation, and so mobilize Ca2+ from intracellular stores, in undifferentiated NG108-15 cells

Journal of Neurochemistry

Volumn 66, Issue 4, 1996, Pages 1462-1467

  Smart, D ^a   Lambert, D G ^a  

^a LEICESTER ROYAL INFIRMARY   (United Kingdom)

Author keywords

Calcium; Inositol 1,4,5 trisphosphate; NG108 15 cells; Phospholipase C; Protein kinase C; Opioid

Indexed keywords

2 [1 (3 AMIDINOTHIOPROPYL) 1H INDOL 3 YL] 3 (1 METHYL 1H INDOL 3 YL)MALEIMIDE; CALCIUM ION; ENKEPHALIN[2,5 DEXTRO PENICILLAMINE]; GUANINE NUCLEOTIDE BINDING PROTEIN; INOSITOL 1,4,5 TRISPHOSPHATE; NALOXONE; NICKEL; OPIATE; PERTUSSIS TOXIN; PHORBOL DIBUTYRATE; PHOSPHOLIPASE C; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR;

ARTICLE; CALCIUM CELL LEVEL; CALCIUM MOBILIZATION; CONTROLLED STUDY; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME INHIBITION; FEEDBACK SYSTEM; NERVE CELL CULTURE; PRIORITY JOURNAL;

ANALGESICS; ANIMALS; CALCIUM; CALCIUM CHANNEL BLOCKERS; DOSE-RESPONSE RELATIONSHIP, DRUG; ENKEPHALIN, D-PENICILLAMINE (2,5)-; ENKEPHALINS; GLIOMA; INOSITOL 1,4,5-TRISPHOSPHATE; NEUROBLASTOMA; NICKEL; NIFEDIPINE; PERTUSSIS TOXIN; PHOSPHOLIPASE C; RECEPTORS, OPIOID, DELTA; TUMOR CELLS, CULTURED; VIRULENCE FACTORS, BORDETELLA;

EID: 0029670367     PISSN: 00223042     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1471-4159.1996.66041462.x     Document Type: Article

References (46)

1. Berridge M. J. (1993) Inositol trisphosphate and calcium signalling Nature 361, 315-325.
2. Challiss R. A. J., Batty I. H., and Nahorski S. R. (1988) Mass measurements of inositol (1,4,5) triphosphate in rat cerebral cortex slices using a radioreceptor assay: effects of neurotransmitters and depolarization. Biochem. Biophys. Res. Commun. 157, 684-691.
3. Chen L. and Huang L. M. (1991) Sustained potentiation of NMDA receptor-mediated glutamate responses through activation of protein kinase C by a μ opioid. Neuron 7, 319-326.
4. Childers S. R. (1991) Opioid receptor coupled second messenger systems. Life Sci. 48, 1991-2003.
5. Connor M. A., Planner A., and Henderson G. (1994) δ and μ opioid receptor mobilization of intracellular calcium in neuroblastoma cells. Regul. Pept. 54, 65-66.
6. Crain S. M. and Shen K. F. (1990) Opioids can evoke direct receptor mediated excitatory effects on sensory neurons. Trends Pharmacol. Sci. 11, 77-81.
7. Davis P. D., Hill C. H., Keech E., Lawton G., Nixon J. S., Sedwick A. D., Wadsworth J., Westmacott D., and Wilkinson S. E (1989) Potent and selective inhibitors of protein kinase C. FEBS Lett. 259, 61-63.
8. Eriksson P. S., Nilsson M., Wagberg M., Hansson E., and Ronnback L. (1993) Kappa-opioid receptors on astrocytes stimulate L-type calcium channels. Neuroscience 54, 401-407.
9. 2+ modulation in human B cell lines. J. Immunol 149, 4074-4081.
10. Jin W., Lee N. M., Loh H. H., and Thayer S. A. (1992) Dual excitatory and inhibitory effects of opioids on intracellular calcium in neuroblastoma X glioma hybrid NG108-15 cells. Mol. Pharmacol. 42, 1083-1089.
11. Jin W., Lee N. M., Loh H. H., and Thayer S. A. (1994) Opioids mobilize calcium from inositol 1,4,5-trisphosphate-sensitive stores in NG108-15 cells. J. Neurosci. 14, 1920-1929.
12. Johnson P. S., Wang J. B., and Uhl G. R. (1994) μ opiate receptor structure function studies II: effects on second messenger systems. Regul. Pept. 54, 139-140.
13. Kaneko S., Nakamura S., Adachi K., Akaike A., and Satoh M. (1994a) Mobilization of intracellular calcium and stimulation of cAMP production by κ opioid receptors expressed in Xenopus oocytes. Mol. Brain Res. 27, 258-264.
14. 2+-mobilizing opioid receptors in Xenopus oocytes injected with rat brain mRNA. Mol. Brain Res. 22, 69-75.
15. Kovoor A., Henry D. J., and Chavkin C. (1995) Agonist-induced desensitization of the mu opioid receptor-coupled potassium channel (GIRK1). J. Biol. Chem. 270, 589-595.
16. Leach R P., Shears S. B., Kirk C. J., and Titheradge M. A. (1986) Changes in free cytosolic calcium and accumulation of inositol phosphates in isolated hepatocytes by [Leu]enkephalin. Biochem. J. 238, 537-542.
17. Leslie F. M. (1987) Methods used for the study of opioid receptors. Pharmacol. Rev. 39, 197-249.
18. Lin Y. and Carpenter D. O. (1994) Direct excitatory effects mediated by non-synaptic actions on rat medial vestibular neurons. Eur. J. Pharmacol 262, 99-106.
19. Lipp J. (1991) Possible mechanisms of morphine analgesia. Clin. Neuropharmacol. 14, 131-147.
20. Lorentz M., Hedlund B., and Arhem P. (1988) Morphine activates calcium channels in cloned mouse neuroblastoma cell lines. Brain Res. 445, 157-159.
21. Mestek A., Hurley J. H., Bye L. S., Campbell A. D., Chen Y., Tian M., Liu J., Schulman H., and Yu L. (1995) The human μ opioid receptor: modulation of functional desensitization by calcium/ calmodulin-dependent protein kinase and protein kinase C. J. Neurosci. 15, 2396-2406.
22. 1 in Xenopus oocytes. FEBS Lett 333, 311-314.
23. Narita M., Makimura M., Feng Y., Hoskins B., and Ho I. K. (1994a) Influence of chronic morphine on protein kinase C activity: comparison with butorphanol and implication for opioid tolerance. Brain Res. 650, 175-179.
24. Narita M., Makimura M., Feng Y., Hoskins B , and Ho I. K. (1994b) A protein kinase inhibitor, H-7, inhibits the development of tolerance to opioid antinociception. Eur. J. Pharmacol. 271, 543-545.
25. Neal M. J., Paterson S. J., and Cunningham J. R. (1994) Enhancement of retinal acetylcholine release by DAMGO: possibly a direct opioid receptor-mediated excitatory effect. Br. J. Pharmacol 113, 789-794.
26. North R. A. (1989) Drug receptors and the inhibition of nerve cells. Br. J. Pharmacol. 98, 13-28.
27. 2-purinergic or bradykinin receptors in NG108-15 cells. Biochem. J. 290, 241-247.
28. 2+/calmodulin- and forskolin-stimulated enzyme activities in rat olfactory bulb. J. Neurochem. 63, 161-168.
29. Penyasamy S. and Hoss W. (1990) Kappa opioid receptors stimulate phosphoinositide turnover in rat brain. Life Sci. 47, 219-225.
30. Porzig H. (1990) Pharmacological modulation of voltage-dependent calcium channels in intact cells. Rev. Physiol. Biochem. Pharmacol. 114, 209-262.
31. Sarne Y., Gafni M., Fields A., and Keren O. (1994) Dual effects of opioids on transmitter release, intracellular calcium and calcium uptake in SK-N-SH cell line. Regul Pept. 54, 253-254.
32. + currents. Br. J. Pharmacol. 116, 2655-2660.
33. Smart D. and Lambert D. G. (1995b) δ-Opioids stimulate inositol (1,4,5)trisphosphate formation in undifferentiated NG108-15 cells. (Abstr.) Analgesia 1 (4-6), 746-749.
34. Smart D., Smith G., and Lambert D. G. (1994) μ-Opioid receptor stimulation of inositol (1,4,5) trisphosphate formation via a pertussis toxin sensitive G protein. J. Neurochem. 62, 1009-1014.
35. Smart D., Smith G., and Lambert D. G. (1995a) μ-Opioids activate phospholipase C in SH-SY5Y human neuroblastoma cells via calcium channel opening. Biochem. J. 305, 577-582.
36. Smart D., Wandless A., and Lambert D. G. (1995b) Activation of phospholipase C in SH-SY5Y neuroblastoma cells by potassium-induced calcium entry. Br. J. Pharmacol. 116, 1797-1800.
37. Stiene-Martin A., Mattson M. P., and Hauser K. F. (1993) Opiates selectively increase intracellular calcium in developing type-1 astrocytes: role of calcium in morphine-induced morphological differentiation. Dev. Brain Res. 76, 189-196.
38. Tang T., Kiang J. G., and Cox B. M. (1994) Opioids acting through delta receptors elicit a transient increase in the intracellular free calcium concentration in dorsal root ganglion-neuroblastoma hybrid ND8-47 cells. J. Pharmacol. Exp. Ther. 270, 40-46.
39. Tobin A. B., Lambert D. G., and Nahorski S. R. (1993) Rapid desensitization of muscarinic m3 receptor stimulated polyphosphoinositide responses. J. Pharmacol. Exp. Ther. 42, 1042-1048.
40. Tsu R. C., Chan J. S. C., and Wong Y. H. (1995) Regulation of multiple effectors by the cloned δ-opioid receptor: stimulation of phospholipase C and type II adenylyl cyclase. J. Neurochem. 64, 2700-2707.
41. Ueda H., Miyamae T., Fukushima N., and Misu Y. (1994) Protein kinase inhibitor potentiates opioid δ-receptor currents in Xenopus oocytes. Neuroreport 5, 1985-1988.
42. Ueda H., Hayashi C., Miyamae T., Watanabe S., Fukushima N., Sasaki Y., and Misu Y. (1995) Homologous and heterologous desensitization of δ-opioid receptor in Xenopus oocytes, COS-cells and guinea pig striatal membranes. (Abstr.) Analgesia 1 (4-6), 793-796.
43. 2+ release from an intracellular pool in myocytes and neurons. Circ. Res. 70, 66-81.
44. 2+ in SH-SY5Y and NG108-15 cells Br. J. Pharmacol. 114, 309P.
45. Wong N. S., Sheng J. Z., Tai K., Bian C. F., and Wong T. M. (1995) Lithium ion alters Ins (1,4,5) P3 production and mobilization of intracellular free calcium in κ-agonist stimulated rat ventricular myocytes. (Abstr.) Analgesia 1 (4-6), 842-845.
46. Zimprich A., Simon T., and Hollt V. (1995) rMOR1 and rMOR1B: comparison of both rat μ opioid receptor variants with respect to second messenger coupling. (Abstr.) Anaglesia 1 (4-6), 886-889