Oxygen infusions (hemoglobin-vesicles and albumin-hemes) based on nano-molecular sciences

Polymers for Advanced Technologies

Volumn 16, Issue 2-3, 2005, Pages 73-83

  Tsuchida, Eishun ^a   Sakai, Hiromi ^a   Komatsu, Teruyuki ^a   Takeoka, Shinji ^a   Huang, Yubin ^a   Sou, Keitaro ^a   Nakagawa, Akito ^a   Teramura, Yuji ^a   Kobayashi, Koichi ^b  

^a WASEDA UNIVERSITY   (Japan)

^b KEIO UNIVERSITY   (Japan)

Author keywords

Biomaterials; Blood substitutes; Oxygen infusion; Surface modification; Water soluble polymers

Indexed keywords

CELLS; CONCENTRATION (PROCESS); HEMOGLOBIN; MACROMOLECULES; METABOLISM; NANOSTRUCTURED MATERIALS; OXYGEN; PROTEINS; ULTRAFILTRATION;

HUMAN SERUM ALBUMIN (HSA); NANO-MOLECULAR SCIENCES; OXYGEN INFUSIONS; RED CELLS;

BLOOD VESSELS;

POLYMER SCIENCE;

EID: 15544366740     PISSN: 10427147     EISSN: None     Source Type: Journal    
DOI: 10.1002/pat.559     Document Type: Article

References (58)

1. Tsuchida E (ed.). Macromolecular Complexes, Dynamic Interactions and Electronic Processes. VCH: New York, 1991.
2. Ciardelli F, Tsuchida E. Wöhrle D (eds). Macromolecule-metal Complexes. VCH: New York, 1996.
3. Matsushita Y, Hasegawa E, Eshima K, Tsuchida E. Synthesis of amphiphilic porphinatoiron complexes having phosphocholine groups. Chem. Lett. 1983; 1387-1389.
4. Tsuchida E. Liposome-embedded iron-porphyrins as an artificial oxygen carrier. Ann. New York Acad. Sci. 1985; 446: 429-442.
5. Tsuchida E, Nishide H. Hemoglobin model-artificial oxygen carrier composed of porphinatoiron complexes. Top. Curr. Chem. 1986; 132: 63-99.
6. Komatsu T, Moritake M, Nakagawa A, Tsuchida E. Self-organized lipid-porphyrin bilayer membranes in vesicular form: nanostructure, photophysical properties and dioxygen coordination. Chem. Eur. J. 2002; 8: 5469-5480.
7. Chang TMS. Blood Substitutes: Principles, Methods, Products, and Clinical Trials. Karger: Basel, 1997.
8. Riess JG. Oxygen carriers ("blood substitutes")-raison d'etre, chemistry, and some physiology. Chem. Rev. 2001; 101: 2797-2919.
9. Sloan EP, Koenigsberg M, Gens D, Cipolle M, Runge J, Mallory MN, Rodman G Jr. Diaspirin cross-linked hemoglobin (DCLHb) in the treatment of severe traumatic hemorrhagic shock. JAMA 1999; 282: 1857-1864.
10. Tsuchida E. Blood Substitutes: Present and Future Perspectives. Elsevier: Amsterdam, 1998.
11. Djordjevich L, Mayoral J, Miller IF, Ivankovich AD. Cardiorespiratory effects of exchange transfusions with synthetic erythrocytes in rats. Crit. Care Med. 1987, 15: 318-323.
12. Takeoka S, Ohgushi T, Yokohama H, Sakai H, Nishide H, Tsuchida E. Preparation conditions of human hemoglobin vesicles covered with lipid membrane. Artif. Organs Today 1993; 3: 129-136.
13. Sakai H, Takeoka S, Yokohama H, Seino Y, Nishide H, Tsuchida E. Purification of concentrated Hb using organic solvent and heat treatment. Protein Expression Purif. 1993; 4: 563-569.
14. Takeoka S, Ohgushi T, Terase K, Ohmori T, Tsuchida E. Layer-controlled hemoglobin vesicles by interaction of hemoglobin with a phospholipid assembly. Langmuir 1996; 12: 1755-1759.
15. Naito Y, Fukutomi I, Masada Y, Sakai H, Takeoka S, Tsuchida E, Abe H, Hirayama J, Ikebuchi K, Ikeda H. Virus removal from hemoglobin solution using Planova membrane. J. Artif. Organs 2002; 5: 141-145.
16. Fukutomi I, Sakai H, Takeoka S, Nishide H, Tsuchida E, Sakai K. Carbonylation of oxyhemoglobin solution using a membrane oxygenator. J. Artif. Organs 2002; 5: 102-107.
17. Sou K, Endo T, Takeoka S, Tsuchida E. Poly(ethylene glycol)-modification of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles. Bioconjugate Chem. 2000; 11: 372-379.
18. Sakai H, Tomiyama K, Sou K, Takeoka S, Tsuchida E. Poly(ethyleneglycol)-conjugation and deoxygenation enable long term preservation of hemoglobin vesicles as oxygen carriers. Bioconjugate Chem. 2000; 11: 425-432.
19. Sou K, Naito Y, Endo T, Takeoka S, Tsuchida E. Effective encapsulation of proteins into size-controlled phospholipid vesicles using the freeze-thawing and extrusion. Biotechnol. Prog. 2003; 19: 1547-1552.
20. Izumi Y, Sakai H, Hamada K, Takeoka S, Yamahata T, Kato R, Nishide H, Tsuchida E, Kobayashi K. Physiologic responses to exchange transfusion with hemoglobin vesicles as an artificial oxygen carrier in anesthetized rats: changes in mean arterial pressure and renal cortical tissue oxygen tension. Crit. Care Med. 1996; 24: 1869-1873.
21. Izumi Y, Sakai H, Kose T, Hamada K, Takeoka S, Yoshizu A, Horinouchi H, Kato R, Nishide H, Tsuchida E, Kobayashi K. Evaluation of the capabilities of a hemoglobin vesicle as an artificial oxygen carrier in a rat exchange transfusion model. ASAIO J. 1997; 43: 289-297.
22. Kobayashi K, Izumi Y, Yoshizu A, Horinouchi H, Park SI, Sakai H, Takeoka S, Nishide H, Tsuchida E. The oxygen carrying capability of hemoglobin vesicles evaluated in rat exchange transfusion models. Artif. Cells Blood Substitues Immobilization Biotechnol. 1997, 25: 357-366.
23. Sakai H, Takeoka S, Park SI, Kose T, Nishide H, Izumi Y, Yoshizu A, Kobayashi K, Tsuchida E. Surface modification of hemoglobin vesicles with poly(ethyleneglycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats. Bioconjugate Chem. 1997; 8: 23-30.
24. Sakai H, Tsai AG, Kerger H, Park SI, Takeoka S, Nishide H, Tsuchida E, Intaglietta M. Subcutaneous microvascular responses to hemodilution with a red cell substitute consisting of polyethyleneglycol-modified vesicles encapsulating hemoglobin. J. Biomed. Mater. Res. 1998; 40: 66-78.
25. 2 affinity. Am. J. Physiol. 1999; 276: H553-H562.
26. Sakai H, Takeoka S, Wettstein R, Tsai AG, Intaglietta M, Tsuchida E. Systemic and microvascular responses to the hemorrhagic shock and resuscitation with Hb-vesicles. Am. J. Physiol. Heart Circ. Physiol. 2002; 283: H1191-H1199.
27. Erni D, Wettstein R, Schramm S, Contaldo C, Sakai H, Takeoka S, Tsuchida E, Leunig M, Banic A. Normovolemic hemodilution with hemoglobin-vesicle solution attenuates hypoxia in ischemic hamster flap tissue. Am. J. Physiol. Heart Circ. Physiol. 2003; 284: H1702-H1709.
28. 2 affinity. Am. J. Physiol. Heart Circ. Physiol. 2003; 285: H1140-H1147.
29. Goda N, Suzuki K, Naito M, Takeoka S, Tsuchida E, Ishimura Y, Tamatani T, Suematsu M. Distribution of heme oxygenase isoform in rat liver: topographic basis for carbon monoxide-mediated micorvascular relaxation. J. Clin. Invest. 1998; 101: 604-612.
30. 2 carriers determine constriction of resistance arteries and hypertension in conscious hamster model. Am. J. Physiol. Heart Circ. Physiol. 2000; 279: H908-H915.
31. Wakamoto S, Fujihara M, Abe H, Sakai H, Takeoka S, Tsuchida E, Ikeda H, Ikebuchi K. Effects of PEG-modified hemoglobin vesicles on agonist induced platelet aggregation and RANTES release in vitro. Artif. Cells Blood Substitues Immobilization Biotechnol. 2001; 29: 191-201.
32. Kyokane T, Norimizu S, Taniai H, Yamaguchi T, Takeoka S, Tsuchida E, Naito M, Nimura Y, Ishimura Y, Suematsu M. Carbon monoxide from heme catabolism protects against hepatobiliary dysfunction in endotoxin-treated rat liver. Gastroenterology 2001; 120: 1227-1240.
33. Ito T, Fujihara M, Abe H, Yamaguchi M, Wakamoto S, Takeoka S, Sakai H, Tsuchida E, Ikeda H, Ikebuchi K. Effects of poly(ethyleneglycol)-modified hemoglobin vesicles on N formyl-methionyl-leucyl-phenylalanine induced responses of polymorphonuclear neutrophils; in vitro. Artif. Cells Blood Substitues Immobilization Biotechnol. 2001; 29: 427-438.
34. Sakai H, Horinouchi H, Tomiyama K, Ikeda E, Takeoka S, Kobayashi K, Tsuchida E. Hemoglobin-vesicles as oxygen carriers: influence on phagocytic activity and histopathological changes in reticuloendothelial systems. Am. J. Pathol. 2001; 159: 1079-1088.
35. Sakai H, Tomiyama K, Masada Y, Takeoka S, Horinouchi H, Kobayashi K, Tsuchida E. Pretreatment of serum containing Hb-vesicles (oxygen carriers) to avoid their interference in laboratory tests. Clin. Chem. Lab. Med. 2003; 41: 222-231.
36. Sakai H, Horinouchi H, Masada Y, Takeoka S, Kobayashi K, Tsuchida E. Metabolism of hemoglobin-vesicles (artificial oxygen carriers) and their influence on organ functions in a rat model. Biomaterials 2004; 25: 4317-4325.
37. Sakai H, Masada Y, Horinouchi H, Ikeda E, Sou K, Takeoka S, Suematsu M, Kobayashi K, Tsuchida E. Physiologic capacity of reticuloendothelial system for degradation of homoglobin-vesicles (artificial oxygen carriers) after massive intravenous doses by daily repeated infusions for 14 days. J. Pharmacol. Exp. Ther. 2004; 311: 874-884.
38. Curry S, Mandelkow H, Brick P, Franks N. Crystal structure of human serum albumin complexes with fatty acid reveals an asymmetric distribution of binding sites. Nature Struct. Biol. 1998; 5: 827-835.
39. Sumi A, Ohtani W, Kobayashi K, Ohmura T, Yokoyama K, Nishida M, Suyama T. Purification and physicochemical properties of recombinant human serum albumin. In Biotechnology of Blood Proteins, Rivat C, Stoltz JF (eds). John Libbey Eurotext: Montrouge, 1993; vol. 227, 293-298.
40. 2-transport albumin: a new hybrid-haemoprotein incorporating tetraphenylporphinatoiron(II) derivative. Chem. Lett. 1995; 813-814.
41. Tsuchida E, Ando K, Maejima H, Kawai N, Komatsu T, Takeoka S, Nishide H. Properties of oxygen binding by albumin-tetraphenylporphyrinatoiron(II) derivative complexes. Bioconjugate Chem. 1997; 8: 534-538.
42. 2-binding to ortho-substituted tetraphenyl- and tetranaphthyl-porphinatoiron(II) derivatives with a covalently linked axial imidazole. J. Chem. Soc., Dalton Trans. 1998; 2503-2506.
43. 2-coordination structure of human serum albumin incorporating tetrakis(o-pivalamido) phenylporphinatoiron(II) serivatives. Bioconjugate Chem. 1999; 10: 82-86.
44. 2-carrying hemoprotein. Bioconjugate Chem. 1999; 10: 797-802.
45. 2 binding to human serum albumin-heme hybrid. Bioconjugate Chem. 2000; 11: 772-776.
46. Komatsu T, Matsukawa Y, Tsuchida E. Reaction of nitric oxide with synthetic hemoprotein, human serum albumin incorporating tetraphenylporphinatoiron(II) derivatives. Bioconjugate Chem. 2001; 12: 71-75.
47. 2-binding ability. Bioconjugate Chem. 2001; 12: 648-652.
48. 2-Binding properties of double-sided porphyrinatoiron(II)s with polar substituents and their human serum albumin hybrids. Bull. Chem. Soc. Jpn 2001; 74: 1695-1702.
49. Wu Y, Komatsu T, Tsuchida E. Electrochemical studies of albumin-heme hybrid in aqueous media by modified electrode. Inorg. Chim. Acta 2001; 322: 120-124.
50. 2-adduct complex. Bioconjugate Chem. 2003; 13: 397-402.
51. 2-carrier. Polym. Adv. Technol. 2002; 13: 845-850.
52. Nakagawa A, Komatsu T, Ohmichi N, Tsuchida E. Synthetic dioxygen-carrying hemoprotein: human serum albumin including iron(II) complex of protoporphyrin IX with an axially coordinated histidylglycyl-propionate. Chem. Lett. 2003; 32: 504-505.
53. Tsuchida E, Komatsu T, Matsukawa Y, Nakagawa A, Sakai H, Kobayashi K, Suematsu M. Human serum albumin incorporating synthetic heme: red blood cell substitute without hypertension by nitric oxide scavenging. J. Biomed. Mater. Res. 2003; 64A: 257-261.
54. 2-delivery and reduction of the oxidized hemin sites by red blood cells. Bioconjugate Chem. 2000; 11: 46-50.
55. 2-binding property. Macromolecules 1999; 32: 8388-8391.
56. Kobayashi K, Komatsu T, Iwamaru A, Matsukawa Y, Horinouchi H, Watanabe M, Tsuchida E. Oxygenation of hypoxic region in solid tumor by administration of human serum albumin incorporating synthetic hemes. J. Biomed. Mater. Res. 2003; 64A: 48-51.
57. Kobayashi K, Izumi Y, Yamahata T, Sakai H, Takeoka S, Nishide H, Tsuchida E. Efficacy of synthetic oxygen-carrying substances. In Int. Congr. Ser. 1995, 1102 (Shock: from Molecular and Cellular Level to Whole Body). Elsevier: Amsterdam, 1996; 305-310.
58. Horinouchi H, Tajima A, Kobayashi K. Liuid ventilation using artificial oxygen carrier. Artif. Blood 2001; 9: 2-5 (in Japanese).