Effective Encapsulation of Proteins into Size-Controlled Phospholipid Vesicles Using Freeze-Thawing and Extrusion

Biotechnology Progress

Volumn 19, Issue 5, 2003, Pages 1547-1552

  Sou, Keitaro ^a   Naito, Yoshiyasu ^a   Endo, Taro ^a   Takeoka, Shinji ^a   Tsuchida, Eishun ^a  

^a WASEDA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

FREEZE-THAWING;

CHOLESTEROL; ORGANIC ACIDS; PHOSPHOLIPIDS; PROTEINS;

BIOTECHNOLOGY;

COATED MATERIALS, BIOCOMPATIBLE; DRUG DELIVERY SYSTEMS; FREEZING; HEMOGLOBINS; HUMANS; LIPOSOMES; MANUFACTURED MATERIALS; MEMBRANE LIPIDS; MEMBRANES, ARTIFICIAL; PARTICLE SIZE; PHOSPHOLIPIDS; PRESSURE; ULTRAFILTRATION;

EID: 0141977181     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp0201004     Document Type: Article

References (42)

1. Bangham, A. D.; Standish, M. M.; Watkins, J. C. Diffusion of univalent ions across the lamellar of swollen phospholipids. J. Mol. Biol. 1965, 13, 238-252.
2. Liposome Technology; Gregoriadis, G., Ed.; CRC Press: Boca Raton, FL, 1984.
3. Fleischer, S.; Fleischer, B. Model membranes and their characteristics. Methods Enzymol. 1989, 171, 191-394.
4. Lasic, D. D.; Needham, D. The "Stealth" liposome: A prototypical biometerial. Chem. Rev. 1995, 95, 2601-2628.
5. Allen, T. M. Liposomal drug formulations. Rationale for development and what we can expect for the future. Drugs 1998, 56, 747-56.
6. Drummond, D. C.; Meyer, O.; Hong, K.; Kirpotin, D. B.; Papahadjopoulos, D. Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors. Pharmacol. Rev. 1999, 51, 691-743.
7. Maurer, N.; Fenske, D. B.; Cullis, P. R. Developments in liposomal drug delivery systems. Expert Opin. Biol. Ther. 2001, 1, 923-947.
8. Blood Substitute: Present and Future Perspective; Tsuchida, E., Ed.; Elsevier Science: Amsterdam, 1998.
9. Blood Substitutes: Principles, Methods, Products, and Clinical Trials; Chang, T. M. S., Ed.; Karger: Basel, 1997.
10. Rudolph, A. S. Encapsulation of hemoglobin in liposome. In Blood Substitutes. Physiological Basis of Efficacy; Winslow, R. M., Vandegriff, K. D., Intaglietta, M., Eds.; Birkhauser: Boston, 1995; pp 98-104.
11. Djordjevich, L.; Miller, I. F. Synthetic erythrocytes from lipid encapsulated hemoglobin. Exp. Hematol. 1980, 8, 584-592.
12. Hunt, C. A.; Burnett, R. R.; MacGregor, R. D.; Strubbe, A. E.; Lau, D. T.; Taylor, N.; Kawada, H. Synthesis and evaluation of a prototypal artificial red cell. Science 1985, 230, 1165-1168.
13. Jopski, B.; Pirkl, V.; Jaroni, H. W.; Schubert, R.; Schmidt, K. H. Preparation of hemoglobin-containing liposomes using octyl glucoside and octyltetraoxyethylene. Biochim. Biophys. Acta 1989, 978, 79-84.
14. Shew, R. L.; Deamer, D. W. A novel method for encapsulation of macromolecules in liposome. Biochim. Biophys. Acta 1985, 816, 1-8.
15. Brandl, M.; Gregoriadis, G. Entrapment of hemoglobin into liposomes by the dehydration-rehydration method: vesicle characterization and in vivo behavior. Biochim. Biophys. Acta 1994, 1196, 65-75.
16. Zheng, S.; Zheng, Y.; Beissinger, R. L.; Fresco, R., Microencapsulation of hemoglobin in liposomes using a double emulsion, film dehydration/ rehydration approach. Biochim. Biophys. Acta 1994, 1196, 123-130.
17. Beissinger, R. L.; Farmer, M. C.; Gossage, J. L. Liposome-encapsulated hemoglobin as a red cell surrogate. Preparation scale-up. ASIAIO Trans. 1986, 32, 558-563.
18. Yoshioka, H. Surface modification of hemoglobin-containing liposomes with polyethylene-glycol prevents liposome aggregation in blood-plasma. Biomaterials 1991, 12, 861-864.
19. Liu, L.; Yonetani, T. Preparation and characterization of liposome-encapsulated haemoglobin by a freeze-thaw method. J. Microencapsulation 1994, 11, 409-421.
20. Olson, F.; Hunt, C. A.; Szoka, F. C.; Vail, W. J.; Papahadjopoulos, D. Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes, Biochim. Biophys. Acta 1979, 812, 557 9-23.
21. Hope, M. J.; Bally, M. B.; Webb, G.; Cullis, P. R. Production of large unilamellar vesicles by a rapid extrusion procedure. Characterization of size distribution, trapped volume and ability to maintain a membrane potential. Biochim. Biophys. Acta 1985, 812, 55-65.
22. Takeoka, S.; Sakai, H.; Terase, K.; Nishide, H.; Tsuchida, E. Characteristics of Hb-vesicles and encapsulation procedure. Artif. Cells, Blood Substitutes, Immobilization Biotechnol. 1994, 22, 861-866.
23. Takeoka, S.; Ohgushi, T.; Terase, K.; Ohmori, T.; Tsuchida, E. Layer-controlled hemoglobin vesicles by interaction of hemoglobin with a phospholipids assembly. Langmuir 1996, 12, 1775-1759.
24. Sakai, H.; Hamada, K.; Takeoka, S.; Nishide, H.; Tsuchida, E. Physical properties of hemoglobin vesicles as red cell substitutes. Biotechnol. Prog. 1996, 12, 119-125.
25. Gaber, B. P.; Yager, P.; Sheridan, J. P.; Chang, E. L. Encapsulation of hemoglobin in phospholipids vesicles. FEBS Lett. 1983, 153, 285-288.
26. Farmer, M. C.; Gaber, B. P. Liposome-encapsulated hemoglobin as an artificial oxygen-carrying system. Methods Enzymol. 1987, 149, 184-200.
27. Mayer, L. D.; Hope, M. J.; Cullis, P. R. Vesicles of variable sizes produced by a rapid extrusion procedure. Biochim. Biophys. Acta 1986, 858, 161-168.
28. 2-); 4.60 (m, 1H, glu α-CH); 6.55 (m, 1H, -CO-NH-). MS (FAB): calcd for CHNO 696.0; found 696.5 (M+H)+.
29. Sakai, H.; Masada, Y.; Takeoka, S.; Tsuchida, E. Characteristics of bovain hemoglobin as a potential source of hemoglobin-vesicles for an artificial oxygen carrier. J. Biochem. 2002, 131, 611-617.
30. MacDonald, R. C.; Jones, F. D.; Qiu, R. Fragmentation into small vesicles of dioleoylphosphatidylcholine bilayers during freezing and thawing. Biochim. Biophys. Acta 1994, 1191, 362-370.
31. 31P-nuclear magnetic resonance. Eur. Biophys. J. 2000, 29, 184-195
32. Pick, U. Liposome with a large trapping capacity prepared by freezing and thawing of sonicated phospholipids mixtures. Arch. Biochem. Biophys. 1981, 212, 186-194.
33. Lichtenderg, D.; Markello, T. Structural characteristics of phospholipids multilamellar liposomes. J. Pharm. Sci. 1984, 73, 122-125.
34. Crowe, J. H.; Crowe, L. M.; Carpenter, J. F.; Rudolph, A. S.; Wistrom, C. A.; Spargo, B. J.; Anchordoguy, T. J. Interactions of sugars with membranes. Biochim. Biophys. Acta 1988, 947, 367-84.
35. Tanaka, K.; Takeda, T.; Fujii, K.; Miyajima, K. Cryoprotective mechanism of saccharides on freeze-drying of liposome. Chem. Pharm. Bull. 1992, 40, 1-5.
36. Sakai, H.; Takeoka, S.; Park, S. I.; Kose, T.; Nishide, H.; Izumi, Y.; Yoshizu, A.; Kobayashi, K.; Tsuchida, E. Surface modification of hemoglobin vesicles with poly(ethylene glycol) and effects on aggregation, viscosity, and blood flow during 90% exchange transfusion in anesthetized rats. Bioconjugate Chem. 1997, 8, 23-30.
37. Sou, K.; Endo, T.; Takeoka, S.; Tsuchida, E. Poly(ethylene glycol)-modification of the phospholipid vesicles by using the spontaneous incorporation of poly(ethylene glycol)-lipid into the vesicles. Bioconjugate Chem. 2000, 11, 372-379.
38. Sakai, H.; Tomiyama, K.; Sou, K.; Takeoka, S.; Tsuchida, E.; Poly(ethylene glycol)-conjugation and deoxygenation enable long-term preservation of hemoglobin-vesicles as oxygen carriers in a liquid state. Bioconjugate Chem. 2000, 11, 372-379.
39. Takeoka, S.; Mori, K.; Ohkawa, H.; Sou, K.; Tsuchida, E. Sythesis and assembly of poly(ethyleneglycol)-lipids with mono-, di-, and tetraacyl chains and a poly(ethylene glycol) chains of various molecular weights. J. Am. Chem. Soc. 2000, 122, 7927-7935.
40. Nicholas, A. R.; Scott, M. J.; Kennedy, N. I.; Jones, M. N. Effect of grafted poly(ethylene glycol) (PEG) on the size, encapsulation efficiency and permeability of vesicles. Biochim. Biophys. Acta 2000, 1463, 167-178.
41. Gompper, G.; Kroll, D. M. Driven transport of fluid vesicles through narrow pores. Phys. Rev. E. 1995, 52, 4198-4208.
42. Frisken, B. J.; Asman, C.; Patty, P. J. Study of vesicle extrusion. Langmuir 2000, 16, 928-933.