Proteinase inhibition by proform of eosinophil major basic protein (pro-MBP) is a multistep process of intra- and intermolecular disulfide rearrangements

Journal of Biological Chemistry

Volumn 280, Issue 11, 2005, Pages 9823-9832

  Glerup, Simon ^a   Boldt, Henning B ^a   Overgaard, Michael T ^a   Sottrup Jensen, Lars ^a   Giudice, Linda C ^b   Oxvig, Claus ^a  

^a AARHUS UNIVERSITY   (Denmark)

^b STANFORD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELL CULTURE; COMPLEXATION; DIMERIZATION; GROWTH KINETICS; INSULIN; MOLECULAR DYNAMICS; MUTAGENESIS; PATHOLOGY; REACTION KINETICS; REDOX REACTIONS; SULFUR COMPOUNDS;

BINDING PROTEINS; DISULFIDE BONDS; HYPOTHETICAL MODELS; PROTEOLYTIC ACTIVITIES;

ENZYME INHIBITION;

BINDING PROTEIN; CYSTEINE; DISULFIDE; MAJOR BASIC PROTEIN; PREGNANCY ASSOCIATED PLASMA PROTEIN A; PROTEINASE; PROTEINASE INHIBITOR; SOMATOMEDIN;

ACIDIFICATION; ARTICLE; CELL GROWTH; CHEMICAL BOND; CHEMICAL STRUCTURE; COMPLEX FORMATION; DIMERIZATION; ENZYME INHIBITION; ENZYME LINKED IMMUNOSORBENT ASSAY; HUMAN; HUMAN CELL; IN VIVO STUDY; MODEL; MOLECULAR INTERACTION; MOLECULE; MUTAGENESIS; OXIDATION REDUCTION POTENTIAL; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN SECRETION; TISSUE CULTURE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL LINE; CELL PROLIFERATION; CHROMATOGRAPHY; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE; CYTOKINES; DIMERIZATION; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ENZYME INHIBITORS; ENZYME-LINKED IMMUNOSORBENT ASSAY; EOSINOPHIL MAJOR BASIC PROTEIN; GLUTATHIONE; HUMANS; MODELS, BIOLOGICAL; MODELS, CHEMICAL; MODELS, GENETIC; MUTAGENESIS, SITE-DIRECTED; OXIDATION-REDUCTION; OXYGEN; PEPTIDE HYDROLASES; PEPTIDES; PREGNANCY-ASSOCIATED PLASMA PROTEIN-A; PROTEIN BINDING; PROTEIN PRECURSORS; PROTEIN STRUCTURE, TERTIARY; TIME FACTORS; TRANSFECTION;

EID: 15444380186     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413228200     Document Type: Article

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