Chemical modification of the GE 2270A macrocycle (MDL 62,879)

Tetrahedron

Volumn 52, Issue 26, 1996, Pages 8763-8774

  Tavecchia, Paolo ^a   Kurz, Michael ^b   Colombo, Luigi ^a   Bonfichi, Riccardo ^a   Selva, Enrico ^a   Lociuro, Sergio ^a   Marzorati, Ettore ^a   Ciabatti, Romeo ^a  

^a Gruppo Lepetit SpA   (Italy)

^b SANOFI   (France)

Author keywords

[No Author keywords available]

Indexed keywords

GE 2270A; MACROCYCLIC COMPOUND; POLYPEPTIDE;

ANTIBACTERIAL ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; DRUG SYNTHESIS; GRAM POSITIVE BACTERIUM; MASS SPECTROMETRY; NUCLEAR MAGNETIC RESONANCE; PRIORITY JOURNAL; REACTION ANALYSIS; STRUCTURE ACTIVITY RELATION;

BACTERIA (MICROORGANISMS); POSIBACTERIA;

EID: 0029999317     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/0040-4020(96)00417-6     Document Type: Article

References (13)

1. Selva, E.; Beretta, G.; Montanini, N.; Gastaldo, L.; Ferrari, P.; Lorenzetti, R.; Landini, P.; Goldstein, B.P.; Berti, M.; Montanaro, L.; Denaro, M. J. Antibiotics 1991, 44, 693.
2. Bèrdy, J. Hanbook of Antibiotiocs Compounds, CRC Press Inc. 1980.
3. Anborg, P.H., Parmeggiani, A. The EMBO Journal, 1991, 10, 779.
4. Landini, P.; Bandera, M.; Goldstein, B.P.; Ripamonti, F., Soffientini, A.; Islam, K.; Denaro, M. J. Biochem. 1992, 283, 649
5. Parmeggiani, A.; Swart, G.W.M. Annu. Rev. Microbiol. 1985, 39, 557.
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7. Wolf, H.; Hassmann, D.; Fisher, E. Proc. Natl. Acad Sci. U.S.A. 1978, 75, 5324.
8. Tavecchia, P.; Gentili, P.; Kurz, M., Sottani, C.; Bonfichi, R.; Selva, E.; Lociuro, S.; Restelli, E.; Ciabatti, R. Tetrahedron 1995, 51, 4890.
9. Stella, S.; Montanini, N.; Le Monnier, F.; Ferrari, P.; Colombo, L., Marinelli, F.; Landini, P.; Ciciliato, I.; Goldstein, B.P.; Selva, E.; Denaro, M. J. Antibiotics 1995, 48, 780.
10. Shimanaka, K.; Iinuma, H.; Hamada, M.; Ikeno, S.; Tsuchiya, K.S., Arita, M.; Hori, M. J. Antibiotics 1995, 48, 182.
11. Bush, K.L.; Glish, G.L.; McLuckey, S.A. Mass Spectrometry/Mass Spectrometry, VCH, New York, 1988, 82.
12. The HPLC profile of the reaction shows a peak which retention time corresponds to a pure sample of benzaldhyde.
13. Still, W.C. J. Org. Chem. 1978, 43, 2923.