Chemokine receptor CCR2 expression and monocyte chemoattractant protein- 1-mediated chemotaxis in human monocytes: A regulatory role for plasma LDL

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 18, Issue 12, 1998, Pages 1983-1991

  Han, Ki Hoon ^a   Tangirala, Rajendra K ^b   Green, Simone R ^a   Quehenberger, Oswald ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

Author keywords

CCR2; Chemotaxis; LDL; Monocyte chemoattractant protein 1

Indexed keywords

CHEMOKINE RECEPTOR; LOW DENSITY LIPOPROTEIN; MONOCYTE CHEMOTACTIC PROTEIN 1;

ARTICLE; ATHEROSCLEROSIS; BLOOD VESSEL INJURY; CHEMOTAXIS; DRUG RECEPTOR BINDING; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; HYPERCHOLESTEROLEMIA; LIPOPROTEIN BLOOD LEVEL; MONOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; RECEPTOR UPREGULATION; SUBENDOTHELIUM;

EID: 0008415688     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.ATV.18.12.1983     Document Type: Article

References (13)

1. Steinberg D, Parthasarathy S, Carew TE, Khoo JC, Witztum JL. Beyond cholesterol: modifications of low-density lipoprotein that increase its atherogenicity. N Engl J Med. 1989;320:915-924.
2. Ross R. The pathogenesis of atherosclerosis: a perspective for the 1980s. Nature. 1993;362:801-809.
3. Valente AJ, Rozek MM, Sprague EA, Schwartz CJ. Mechanisms in intimal monocyte-macrophage recruitment: a special role for monocyte chemotactic protein-1. Circulation. 1992;86(suppl III):III-20-III-25.
4. Faruqi RM, DiCorleto PE. Mechanisms of monocyte recruitment and accumulation. Br Heart J. 1993;69:S19-S29.
5. Cushing SD, Berliner JA, Valente AJ, Territo MC, Navab M, Parhami F, Gerrity R, Schwartz CJ, Fogelman AM. Minimally modified low density lipoprotein induces monocyte chemotactic protein 1 in human endothelial cells and smooth muscle cells. Proc Natl Acad Sci U S A. 1990;87: 5134-5138.
6. Navab M, Imes SS, Hama SY, Hough GP, Ross LA, Bork RW, Valente AJ, Berliner JA, Drinkwater DC, Laks H. Monocyte transmigration induced by modification of low density lipoprotein in cocultures of human aortic wall cells is due to induction of monocyte chemotactic protein 1 synthesis and is abolished by high density lipoprotein. J Clin Invest. 1991:88:2039-2046.
7. Rollins BJ, Morrison ED, Stiles CD. Cloning and expression of JE, a gene inducible by platelet-derived growth factor and whose product has cytokine-like properties. Proc Natl Acad Sci U S A. 1988;85:3738-3742.
8. Yoshimura T, Robinson EA, Tanaka S, Appella E, Kuratsu J, Leonard EJ. Purification and amino acid analysis of two human glioma-derived monocyte chemoattractants. J Exp Med. 1989;169:1449-1459.
9. Baggiolini M, Dewald B, Moser B. Human chemokines: an update. Annu Rev Immunol. 1997;15:675-705.
10. Rollins BJ, Yoshimura T, Leonard EJ, Pober JS. Cytokine-activated human endothelial cells synthesize and secrete a monocyte chemoattractant, MCP-l/JE. Am J Pathol. 1990;136:1229-1233.
11. Shyy YJ, Wickham LL, Hagan JP, Hsieh HJ, Hu YL, Telian SH, Valente AJ, Sung KL, Chien S. Human monocyte colony-stimulating factor stimulates the gene expression of monocyte chemotactic protein-1 and increases the adhesion of monocytes to endothelial monolayers. J Clin Invest. 1993;92:1745-1751.
12. Brown Z, Gerritsen ME, Carley WW, Stricter RM, Kunkel SL, Westwick J. Chemokine gene expression and secretion by cytokine-activated human microvascular endothelial cells: differential regulation of monocyte chemoattractant protein-1 and interleukin-8 in response to interferon-γ. Am J Pathol. 1994;145:913-921.
13. Wenzel UO, Fouqueray B, Grandaliano G, Kim YS, Karamitsos C, Valente AJ, Abboud HE. Thrombin regulates expression of monocyte chemoattractant protein-1 in vascular smooth muscle cells. Circ Res. 1995;77:503-509.