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Volumn 5, Issue 5, 2003, Pages 399-405

Molecular predictors of treatment and outcome in colorectal cancer

Author keywords

[No Author keywords available]

Indexed keywords

ANTINEOPLASTIC AGENT; CAPECITABINE; CISPLATIN; DIHYDROPYRIMIDINE DEHYDROGENASE; EXCISION REPAIR CROSS COMPLEMENTING PROTEIN 1; FLUOROPYRIMIDINE; FLUOROURACIL; FOLINIC ACID; GENE PRODUCT; IRINOTECAN; MOLECULAR MARKER; OXALIPLATIN; PHOSPHORYLASE; PLATINUM DERIVATIVE; THYMIDYLATE PHOSPHORYLASE; THYMIDYLATE SYNTHASE; UNCLASSIFIED DRUG; TUMOR MARKER;

EID: 1542705896     PISSN: 15228037     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11894-003-0053-3     Document Type: Review
Times cited : (5)

References (33)
  • 1
    • 0004312588 scopus 로고    scopus 로고
    • Atlanta, GA: ACS Surveillance Research
    • Cancer Facts and Figures. Atlanta, GA: ACS Surveillance Research; 2003.
    • (2003) Cancer Facts and Figures
  • 3
    • 0034727063 scopus 로고    scopus 로고
    • Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer
    • Saltz LB, Cox JV, Blanke C, et al.: Irinotecan plus fluorouracil and leucovorin for metastatic colorectal cancer. N Engl J Med 2000, 343:905-914.
    • (2000) N. Engl. J. Med. , vol.343 , pp. 905-914
    • Saltz, L.B.1    Cox, J.V.2    Blanke, C.3
  • 4
    • 0027436244 scopus 로고
    • The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: Results from National Surgical Adjuvant Breast and Bowel Project protocol C-03
    • Wolmark N, Rockette H, Fisher B, et al.: The benefit of leucovorin-modulated fluorouracil as postoperative adjuvant therapy for primary colon cancer: results from National Surgical Adjuvant Breast and Bowel Project protocol C-03. J Clin Oncol 1993, 11:1879-1887.
    • (1993) J. Clin. Oncol. , vol.11 , pp. 1879-1887
    • Wolmark, N.1    Rockette, H.2    Fisher, B.3
  • 5
    • 0035912144 scopus 로고    scopus 로고
    • Molecular predictors of survival after adjuvant chemotherapy for colon cancer
    • Watanabe T, Wu TT, Catalano PJ, et al.: Molecular predictors of survival after adjuvant chemotherapy for colon cancer. N Engl J Med 2001, 344:1196-1206.
    • (2001) N. Engl. J. Med. , vol.344 , pp. 1196-1206
    • Watanabe, T.1    Wu, T.T.2    Catalano, P.J.3
  • 6
    • 0035321315 scopus 로고    scopus 로고
    • Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa
    • Miyamoto S, Ochiai A, Boku N, et al.: Discrepancies between the gene expression, protein expression, and enzymatic activity of thymidylate synthase and dihydropyrimidine dehydrogenase in human gastrointestinal cancers and adjacent normal mucosa. Int J Oncol 2001, 18:705-713.
    • (2001) Int. J. Oncol. , vol.18 , pp. 705-713
    • Miyamoto, S.1    Ochiai, A.2    Boku, N.3
  • 7
    • 0022344622 scopus 로고
    • Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells
    • Berger SH, Jeng C-H, Johnson LF, et al.: Thymidylate synthase overproduction and gene amplification in fluorodeoxyuridine-resistant human cells. Mol Pharmacol 1985, 28:461-467.
    • (1985) Mol. Pharmacol. , vol.28 , pp. 461-467
    • Berger, S.H.1    Jeng, C.-H.2    Johnson, L.F.3
  • 8
    • 0028019880 scopus 로고
    • Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: Implications for treatment with fluorouracil
    • Peters GJ, van der Wilt CL, van Groeningen CJ, et al.: Thymidylate synthase inhibition after administration of fluorouracil with or without leucovorin in colon cancer patients: implications for treatment with fluorouracil. J Clin Oncol 1994, 12:2035-2042.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2035-2042
    • Peters, G.J.1    van der Wilt, C.L.2    van Groeningen, C.J.3
  • 9
    • 0028151449 scopus 로고
    • The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer
    • Johnston PG, Fisher ER, Rockette HE, et al.: The role of thymidylate synthase expression in prognosis and outcome of adjuvant chemotherapy in patients with rectal cancer. J Clin Oncol 1994, 12:2640-2647.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2640-2647
    • Johnston, P.G.1    Fisher, E.R.2    Rockette, H.E.3
  • 10
    • 15444349773 scopus 로고    scopus 로고
    • p53 and thymidylate synthase expression in untreated stage II colon cancer: Associations with recurrence, survival, and site
    • Lenz HJ, Danenberg KD, Leichman CG, et al.: p53 and thymidylate synthase expression in untreated stage II colon cancer: associations with recurrence, survival, and site. Clin Cancer Res 1998, 4:1227-1234.
    • (1998) Clin. Cancer. Res. , vol.4 , pp. 1227-1234
    • Lenz, H.J.1    Danenberg, K.D.2    Leichman, C.G.3
  • 11
    • 0032997572 scopus 로고    scopus 로고
    • Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy
    • Aschele C, Domizia D, Stefania C, et al.: Immunohistochemical quantitation of thymidylate synthase expression in colorectal cancer metastases predicts for clinical outcome to fluorouracil-based chemotherapy. J Clin Oncol 1999, 17:1760-1770.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 1760-1770
    • Aschele, C.1    Domizia, D.2    Stefania, C.3
  • 12
    • 0028940399 scopus 로고
    • Thymidylate synthase protein and gene expression predicts for response to 5-fluorouracil, leucovorin in patients with colorectal and gastric cancer
    • Johnston PG, Lenz H-J, Leichman CG, et al.: Thymidylate synthase protein and gene expression predicts for response to 5-fluorouracil, leucovorin in patients with colorectal and gastric cancer. Cancer Res 1995, 55:1407-1412.
    • (1995) Cancer Res. , vol.55 , pp. 1407-1412
    • Johnston, P.G.1    Lenz, H.-J.2    Leichman, C.G.3
  • 13
    • 0030883708 scopus 로고    scopus 로고
    • Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin
    • Leichman CG, Lenz HJ, Leichman L, et al.: Quantitation of intratumoral thymidylate synthase expression predicts for disseminated colorectal cancer response and resistance to protracted-infusion fluorouracil and weekly leucovorin. J Clin Oncol 1997, 15:3223-3229.
    • (1997) J. Clin. Oncol. , vol.15 , pp. 3223-3229
    • Leichman, C.G.1    Lenz, H.J.2    Leichman, L.3
  • 14
    • 0031722179 scopus 로고    scopus 로고
    • High basal level gene expression of thymidine phosphorylase (platelet derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil
    • Metzger R, Danenberg K, Leichman CG, et al.: High basal level gene expression of thymidine phosphorylase (platelet derived endothelial cell growth factor) in colorectal tumors is associated with nonresponse to 5-fluorouracil. Clin Cancer Res 1998, 4:2371-2376.
    • (1998) Clin. Cancer. Res. , vol.4 , pp. 2371-2376
    • Metzger, R.1    Danenberg, K.2    Leichman, C.G.3
  • 15
    • 0032520168 scopus 로고    scopus 로고
    • Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts
    • Ishikawa T, Sekiguchi F, Fukase Y, et al.: Positive correlation between the efficacy of capecitabine and doxifluridine and the ratio of thymidine phosphorylase to dihydropyrimidine dehydrogenase activities in tumors in human cancer xenografts. Cancer Res 1998, 58:685-690.
    • (1998) Cancer Res. , vol.58 , pp. 685-690
    • Ishikawa, T.1    Sekiguchi, F.2    Fukase, Y.3
  • 16
    • 0027945196 scopus 로고
    • Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy
    • Diaso RB, Lu Z: Dihydropyrimidine dehydrogenase activity and fluorouracil chemotherapy. J Clin Oncol 1994, 12:2239-2242.
    • (1994) J. Clin. Oncol. , vol.12 , pp. 2239-2242
    • Diaso, R.B.1    Lu, Z.2
  • 17
    • 0023902287 scopus 로고
    • Familial deficiency of DPD: Biochemical basis for familial pyrimidinemia severe 5-FU induced toxicity
    • Diaso RB, Beavers TL, Carpenter JT: Familial deficiency of DPD: biochemical basis for familial pyrimidinemia severe 5-FU induced toxicity. J Clin Invest 1988, 81:47-51.
    • (1988) J. Clin. Invest. , vol.81 , pp. 47-51
    • Diaso, R.B.1    Beavers, T.L.2    Carpenter, J.T.3
  • 18
    • 0027426408 scopus 로고
    • DPD activity in human peripheral blood mononuclear cells and liver: Population characteristics, newly identified deficient patients and clinical implications in 5-FU chemotherapy
    • Lu Z, Zhang R, Diasio RB: DPD activity in human peripheral blood mononuclear cells and liver: population characteristics, newly identified deficient patients and clinical implications in 5-FU chemotherapy. Cancer Res 1993, 53:5433-5438.
    • (1993) Cancer Res. , vol.53 , pp. 5433-5438
    • Lu, Z.1    Zhang, R.2    Diasio, R.B.3
  • 19
    • 0003339957 scopus 로고    scopus 로고
    • DPD and TS gene expressions identify a high percentage of colorectal tumors responding to 5-FU
    • [abstract]
    • Danenberg K, Salonga D, Park CG, et al.: DPD and TS gene expressions identify a high percentage of colorectal tumors responding to 5-FU [abstract]. Proc ASCO 1998, 17:992.
    • (1998) Proc. ASCO , vol.17 , pp. 992
    • Danenberg, K.1    Salonga, D.2    Park, C.G.3
  • 20
    • 0032745499 scopus 로고    scopus 로고
    • Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer
    • Uetake H, Ichikawa W, Takechi T, et al.: Relationship between intratumoral dihydropyrimidine dehydrogenase activity and gene expression in human colorectal cancer. Clin Cancer Res 1999, 5:2836-2839.
    • (1999) Clin. Cancer Res. , vol.5 , pp. 2836-2839
    • Uetake, H.1    Ichikawa, W.2    Takechi, T.3
  • 21
    • 0034048729 scopus 로고    scopus 로고
    • Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase
    • Salonga D, Danenberg M, Metzger R, et al.: Colorectal tumors responding to 5-fluorouracil have low gene expression levels of dihydropyrimidine dehydrogenase, thymidylate synthase, and thymidine phosphorylase. Clin Cancer Res 2000, 6:1322-1327.
    • (2000) Clin. Cancer Res. , vol.6 , pp. 1322-1327
    • Salonga, D.1    Danenberg, M.2    Metzger, R.3
  • 22
    • 0029122937 scopus 로고
    • Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase
    • Horie N, Aiba H, Oguro K, et al.: Functional analysis and DNA polymorphism of the tandemly repeated sequences in the 5′-terminal regulatory region of the human gene for thymidylate synthase. Cell Struct Funct 1995, 20:191-197.
    • (1995) Cell Struct. Funct. , vol.20 , pp. 191-197
    • Horie, N.1    Aiba, H.2    Oguro, K.3
  • 23
    • 0035750549 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy
    • Pullarkat ST, Stoehlmacher J, Ghaderi V, et al.: Thymidylate synthase gene polymorphism determines response and toxicity of 5-FU chemotherapy. Pharmacogenomics J 2001, 1:65-70.
    • (2001) Pharmacogenomics J. , vol.1 , pp. 65-70
    • Pullarkat, S.T.1    Stoehlmacher, J.2    Ghaderi, V.3
  • 24
    • 0033427561 scopus 로고    scopus 로고
    • Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers
    • Kawakami K, Omura K, Kanehira E, et al.: Polymorphic tandem repeats in the thymidylate synthase gene is associated with its protein expression in human gastrointestinal cancers. Anticancer Res 1999, 19:3249-3252.
    • (1999) Anticancer. Res. , vol.19 , pp. 3249-3252
    • Kawakami, K.1    Omura, K.2    Kanehira, E.3
  • 25
    • 0000161515 scopus 로고    scopus 로고
    • Thymidylate synthase genotype and survival benefit from chemotherapy in patients with colorectal cancer
    • [abstract]
    • Elsaleh H, Fabianne G, Joseph D, et al.: Thymidylate synthase genotype and survival benefit from chemotherapy in patients with colorectal cancer [abstract]. Proc ASCO 2001, 20:493.
    • (2001) Proc. ASCO , vol.20 , pp. 493
    • Elsaleh, H.1    Fabianne, G.2    Joseph, D.3
  • 26
    • 0036355046 scopus 로고    scopus 로고
    • Thymidylate synthase gene polymorphism predicts response to capecitabine chemotherapy in advanced colorectal cancer
    • Park DJ, Stoehlmacher J, Zhang W, et al.: Thymidylate synthase gene polymorphism predicts response to capecitabine chemotherapy in advanced colorectal cancer. Int J Colorectal Dis 2001, 17:46-49.
    • (2001) Int. J. Colorectal. Dis. , vol.17 , pp. 46-49
    • Park, D.J.1    Stoehlmacher, J.2    Zhang, W.3
  • 27
    • 0025054962 scopus 로고
    • Nucleotide excision repair in Escherichia coli
    • Van Houten B: Nucleotide excision repair in Escherichia coli. Microbiol Rev 1990, 54:18-51.
    • (1990) Microbiol. Rev. , vol.54 , pp. 18-51
    • Van Houten, B.1
  • 28
    • 0027221911 scopus 로고
    • Nucleotide excision repair. II: From yeast to mammals
    • Hoeijmakers JH: Nucleotide excision repair. II: From yeast to mammals. Trends Genet 1993, 9:211-217.
    • (1993) Trends Genet. , vol.9 , pp. 211-217
    • Hoeijmakers, J.H.1
  • 29
    • 0033874892 scopus 로고    scopus 로고
    • Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer
    • de Gramont A, Figer A, Seymour M, et al.: Leucovorin and fluorouracil with or without oxaliplatin as first-line treatment in advanced colorectal cancer. J Clin Oncol 2000, 18:2938-2947.
    • (2000) J. Clin. Oncol. , vol.18 , pp. 2938-2947
    • de Gramont, A.1    Figer, A.2    Seymour, M.3
  • 30
    • 0032730143 scopus 로고    scopus 로고
    • Multicenter phase II study of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen
    • de Gramont A, Bensmaine MA, Louvet C, et al.: Multicenter phase II study of bimonthly high-dose leucovorin, fluorouracil infusion, and oxaliplatin for metastatic colorectal cancer resistant to the same leucovorin and fluorouracil regimen. J Clin Oncol 1999, 17:3560-3568.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3560-3568
    • de Gramont, A.1    Bensmaine, M.A.2    Louvet, C.3
  • 31
    • 0001430825 scopus 로고    scopus 로고
    • N9741: Oxaliplatin (oxal) or CPT-11 + 5-fluorouracil (5FU)/leucovorin (LV) or oxal + CPT-11 in advanced colorectal cancer (CRC): Initial toxicity and response data from a GI Intergroup study
    • [abstract]
    • Goldberg RM, Morton RF, Sargent DJ, et al.: N9741: oxaliplatin (oxal) or CPT-11 + 5-fluorouracil (5FU)/leucovorin (LV) or oxal + CPT-11 in advanced colorectal cancer (CRC): initial toxicity and response data from a GI Intergroup study [abstract]. Proc ASCO 2002, 21:511.
    • (2002) Proc. ASCO , vol.21 , pp. 511
    • Goldberg, R.M.1    Morton, R.F.2    Sargent, D.J.3
  • 32
    • 0035576102 scopus 로고    scopus 로고
    • ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy
    • Shirota Y, Stoehlmacher J, Brabender J, et al.: ERCC1 and thymidylate synthase mRNA levels predict survival for colorectal cancer patients receiving combination oxaliplatin and fluorouracil chemotherapy. J Clin Oncol 2001, 19:4298-4304.
    • (2001) J. Clin. Oncol. , vol.19 , pp. 4298-4304
    • Shirota, Y.1    Stoehlmacher, J.2    Brabender, J.3
  • 33
    • 0012662694 scopus 로고    scopus 로고
    • ERCC1 polymorphism associated with ERCC1 mRNA expression
    • [abstract]
    • Park D, Stoehlmacher J, Zhang W, et al.: ERCC1 polymorphism associated with ERCC1 mRNA expression [abstract]. Proc AACR 2002, 43:1591.
    • (2002) Proc. AACR , vol.43 , pp. 1591
    • Park, D.1    Stoehlmacher, J.2    Zhang, W.3


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