Regulation of the Properties of the Heme-NO Complexes in Nitric-oxide Synthase by Hydrogen Bonding to the Proximal Cysteine

Journal of Biological Chemistry

Volumn 276, Issue 41, 2001, Pages 38280-38288

  Couture, Manon ^a   Adak, Subrata ^b   Stuehr, Dennis J ^b   Rousseau, Denis L ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b LERNER RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CATALYSIS; COMPLEXATION; ENZYMES; HYDROGEN BONDS; MUTAGENESIS; NITROGEN OXIDES; RAMAN SPECTROSCOPY;

NEURONAL ISOFORMS;

BIOCHEMISTRY;

ARGININE; CITRULLINE; CYSTEINE; HEME; ISOENZYME; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; OXYGEN; SULFUR; TRYPTOPHAN;

ARTICLE; BINDING AFFINITY; BINDING KINETICS; CHEMICAL BOND; COMPARATIVE STUDY; COMPLEX FORMATION; DISSOCIATION CONSTANT; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITION; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; RAMAN SPECTROMETRY; REGULATORY MECHANISM; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; MUTATION; PROTEIN CONFORMATION;

CYSTEINE; HEME; HYDROGEN BONDING; MODELS, MOLECULAR; MUTATION; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROTEIN CONFORMATION; SPECTRUM ANALYSIS, RAMAN; TRYPTOPHAN;

EID: 0035851202     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (54)

1. Hardison, R. C. (1996) Proc. Natl. Acad. Sci. U. S. A. 93, 5675-5679
2. Rodgers, K. R. (1999) Curr. Opin. Chem. Biol. 3, 158-167
3. Liu, L., Zeng, M., Hausladen, A., Heitman, J., and Stamler, J. S. (2000) Proc. Natl. Acad. Sci. U. S. A. 97, 4672-4676
4. Feldman, P. L., Griffith, O. W., and Stuehr, D. J. (1993) Chem. Eng. News 71, 26-38
5. Marletta, M. A. (1993) J. Biol. Chem. 268, 12231-12234
6. Raman, C. S., Martasek, P., and Masters, B. S. S. (2000) in The Porphyrin Handbook (Kadish, K. M., Smith, K. M., and Guilard, R., eds) Vol. 4, pp. 293-339, Academic Press, New York
7. Schmidt, H. H. H. W., and Walter, U. (1994) Cell 78, 919-925
8. Griffith, O. W., and Stuehr, D. J. (1995) Annu. Rev. Physiol. 57, 707-736
9. Abu-Soud, H. M., Wang, J., Rousseau, D. L., Fukuto, J. M., Ignarro, L. J., and Stuehr, D. J. (1995) J. Biol. Chem. 270, 22997-23006
10. Abu-Soud, H. M., Gachhui, R., Raushel, F. M., and Stuehr, D. J. (1997) J. Biol. Chem. 272, 17349-17353
11. Hurshman, A. R., and Marletta, M. A. (1995) Biochemistry 34, 5627-5634
12. Crane, B. R., Arvai, A. S., Ghosh, D. K., Wu, C., Getzoff, E. D., Stuehr, D. J., and Tainer, J. A. (1998) Science 279, 2121-2126
13. Fischmann, T. O., Hruza, A., Niu, X. D., Fossetta, J. D., Lunn, C. A., Dolphin, E., Pronguay, A. J., Reichert, P., Lundell, D. J., Narula, S. K., and Weber, P. C. (1999) Nat. Struct. Biol. 6, 233-242
14. Raman, C. S., Li, H., Martasek, P., Kral, V., Masters, B. S., and Poulos, T. L. (1998) Cell 95, 939-950
15. Poulos, T. L. (2000) in The Porphyrin Handbook (Kadish, K. M., Smith, K. M., and Guilard, R., eds) Vol. 4, pp. 189-218, Academic Press, New York
16. Yoshioka, S., Takahashi, S., Ishimori, K., and Morishima, I. (2000) J. Inorg. Biochem. 81, 141-151
17. Hu, S., and Kincaid, J. R. (1993) J. Biol. Chem. 268, 6189-6193
18. Bangeharoenpaurpong, O., Champion, P. M., Hall, K. S., and Hager, L. P. (1986) Biochemistry 25, 2374-2378
19. Champion, P. M., Stallard, B. R., Wagner, G. C., and Gunsalus, I. C. (1982) J. Am. Chem. Soc. 104, 5469-5472
20. Wang, J., Rousseau, D. L., Abu-Soud, H. M., and Stuehr, D. J. (1994) Proc. Natl. Acad. Sci. U. S. A. 91, 10512-10516
21. Adak, S., Crooks, C., Wang, Q., Crane, B. R., Tainer, J. A., Getzoff, E. D., and Stuehr, D. J. (1999) J. Biol. Chem. 274, 26907-26911
22. Adak, S., Wang, Q., and Stuehr, D. J. (2000) J. Biol. Chem. 275, 17434-17439
23. Abu-Soud, H. M., Ichimori, K., Presta, A., and Stuehr, D. J. (2000) J. Biol. Chem. 275, 17349-17357
24. Abu-Soud, H. M., Loftus, M., and Stuehr, D. J. (1995) Biochemistry 34, 11167-11175
25. Hu, S., Smith, K. S., and Spiro, T. G. (1996) J. Am. Chem. Soc. 118, 12638-12646
26. Spiro, T. G., and Li, X. Y. (1988) in Biological Applications of Raman Spectroscopy (Spiro, T. G., ed) pp. 1-37, John Wiley & Sons, Inc., New York
27. Wang, J., Caughey, W. S., and Rousseau, D. L. (1996) in Methods in Nitric Oxide Research (Feelisch, M., and Stamler, J., eds) pp. 427-454, John Wiley & Sons, Inc., New York
28. Wang, J., Stuehr, D. J., and Rousseau, D. L. (1995) Biochemistry 34, 7080-7087
29. Yeh, S.-R., Han, S., and Rousseau, D. L. (1998) Acc. Chem. Res. 31, 727-736
30. Reynolds, M. F., Parks, R. B., Burstyn, J. N., Shelver, D., Thorsteinsson, M. V., Kerby, R. L., Roberts, G. P., Vogel, K. M., and Spiro, T. G. (2000) Biochemistry 39, 388-396
31. Schelvis, J. P., Zhao, Y., Marletta, M. A., and Babcock, G. T. (1998) Biochemistry 37, 16289-16297
32. Decatur, S. M., Franzen, S., DePillis, G. D., Dyer, R. B., Woodruff, W. H., and Boxer, S. G. (1996) Biochemistry 35, 4939-4944
33. Abu-Soud, H. M., Wu, C., Ghosh, D. K., and Stuehr, D. J. (1998) Biochemistry 37, 3777-3786
34. Huang, L., Abu-Soud, H. M., Hille, R., and Stuehr, D. J. (1999) Biochemistry 38, 1912-1920
35. Migita, C. T., Salerno, J. C., Masters, B. S. S., Martasek, P., McMillan, K., and Ikeda-Saito, M. (1997) Biochemistry 36, 10987-10992
36. Hu, S., and Kincaid, J. R. (1991) J. Am. Chem. Soc. 113, 2843-2850
37. Obayashi, E., Tsukamoto, K., Adachi, S.-I., Takahashi, S., Nomura, M., Iizuka, T., Shoun, H., and Shiro, Y. (1997) J. Am. Chem. Soc. 119, 7807-7816
38. Chang, C. K., and Dolphin, D. (1975) J. Am. Chem. Soc. 97, 5948-5950
39. Sigman, J. A., Pond, A. E., Dawson, J. H., and Lu, Y. (1999) Biochemistry 38, 11122-11129
40. Adachi, S., Nagano, S., Ishimori, K., Watanabe, Y., Morishima, I., Egawa, T., Kitagawa, T., and Makino, R. (1993) Biochemistry 32, 241-252
41. Liu, Y., Moenne-Loccoz, P., Hildebrand, D. P., Wilks, A., Loehr, T. M., Mauk, A. G., and Ortiz de Montellano, P. R. (1999) Biochemistry 38, 3733-3743
42. Uno, T., Yukinari, A., Tomisugi, Y., Ishikawa, Y., Makino, R., Brannigan, J. A., and Wilkinson, A. J. (2001) J. Am. Chem. Soc. 123, 2458-2459
43. Adak, S., and Stuehr, D. J. (2001) J. Inorg. Biochem. 83, 301-308
44. Santolini, J., Adak, S., Curran, C. M., and Stuehr, D. J. (2001) J. Biol. Chem. 276, 1233-1243
45. Hoshino, M., Maeda, M., Konishi, R., Seki, H., and Ford, P. C. (1996) J. Am. Chem. Soc. 118, 5702-5707
46. Nakano, R., Sato, H., Watanabe, A., Ito, O., and Shimizu, T. (1996) J. Biol. Chem. 271, 8570-8574
47. Sundaramoorthy, M., Terner, J., and Poulos, T. L. (1995) Structure (Lond.) 3, 1367-1377
48. Schlichting, I., Jung, C., and Schulze, H. (1997) FEBS Lett. 415, 253-257
49. Deng, T. J., Proniewicz, L. M., Kincaid, J. R., Yeom, H., Macdonald, I. D., and Sligar, S. G. (1999) Biochemistry 38, 13699-13706
50. Obayashi, E., Takahashi, S., and Shiro, Y. (1998) J. Am. Chem. Soc. 120, 12964-12965
51. Benko, B., and Yu, N. T. (1983) Proc. Natl. Acad. Sci. U. S. A. 80, 7042-7046
52. Hu, S., and Kincaid, J. R. (1991) J. Am. Chem. Soc. 113, 9760-9766
53. Tsubaki, M., and Yu, N. T. (1982) Biochemistry 21, 1140-1144
54. Fan, B., Gupta, G., Danziger, R. S., Friedman, J. M., and Rousseau, D. L. (1998) Biochemistry 37, 1178-1184