Contribution of sensitized P2X receptors in inflamed tissue to the mechanical hypersensitivity revealed by phosphorylated ERK in DRG neurons

Pain

Volumn 108, Issue 3, 2004, Pages 258-266

  Dai, Yi ^a   Fukuoka, Tetsuo ^a   Wang, Hu ^a   Yamanaka, Hiroki ^a   Obata, Koichi ^a   Tokunaga, Atsushi ^a   Noguchi, Koichi ^a  

^a HYOGO COLLEGE OF MEDICINE   (Japan)

Author keywords

ATP; Dorsal root ganglion; Extracellular signal regulated protein kinase; Mechanical hyperalgesia; Pain stimuli; Phosphorylation

Indexed keywords

2' O (TRINITROPHENYL)ADENOSINE 5' TRIPHOSPHATE; ALPHA,BETA METHYLENEADENOSINE TRIPHOSPHATE; MITOGEN ACTIVATED PROTEIN KINASE; PURINE P2X RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; PYRIDOXAL PHOSPHATE 6 AZOPHENYL 2',4' DISULFONIC ACID; UNCLASSIFIED DRUG;

AFFERENT NERVE GROUP 1; ANALGESIC ACTIVITY; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; DOSE RESPONSE; EFFERENT NERVE; ENZYME PHOSPHORYLATION; HYPERALGESIA; IMMUNOREACTIVITY; INFLAMMATION; MALE; MYELINATED NERVE; NERVE CELL; NONHUMAN; PAIN; PAW EDEMA; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; SPINAL GANGLION; STIMULUS RESPONSE;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL COUNT; DISEASE MODELS, ANIMAL; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; FREUND'S ADJUVANT; FUNCTIONAL LATERALITY; GANGLIA, SPINAL; IMMUNOHISTOCHEMISTRY; INFLAMMATION; MALE; MITOGEN-ACTIVATED PROTEIN KINASES; NEUROFILAMENT PROTEINS; NEURONS; PHOSPHORYLATION; PHYSICAL STIMULATION; PLATELET AGGREGATION INHIBITORS; PYRIDOXAL PHOSPHATE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, PURINERGIC P2;

EID: 1542498425     PISSN: 03043959     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.pain.2003.12.034     Document Type: Article

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