Gene expression profiling of human colon xenograft tumors following treatment with SU11248, a multitargeted tyrosine kinase inhibitor

Oncogene

Volumn 23, Issue 8, 2004, Pages 1618-1626

  Morimoto, Alyssa M ^a,c   Tan, Nguyen ^a   West, Kristina ^a   McArthur, Grant ^b   Toner, Guy C ^b   Manning, William C ^a   Smolich, Beverly D ^a   Cherrington, Julie M ^a  

^a SUGEN INC   (United States)

^b PETER MACCALLUM CANCER CENTRE   (Australia)

^c GENENTECH INC   (United States)

Author keywords

Biomarker; Immunohistochemistry; in vivo; Microarray; SU11248

Indexed keywords

BIOLOGICAL MARKER; CADHERIN; CADHERIN 11; FLT3 LIGAND; PLATELET DERIVED GROWTH FACTOR RECEPTOR; PROTEIN TYROSINE KINASE; PROTEIN TYROSINE KINASE INHIBITOR; STEM CELL FACTOR; SUNITINIB; UNCLASSIFIED DRUG; VASCULOTROPIN RECEPTOR; ENZYME INHIBITOR; INDOLE DERIVATIVE; OSTEOBLAST CADHERIN; PYRROLE DERIVATIVE;

ANGIOGENESIS; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; COLON TUMOR; CONTROLLED STUDY; DRUG MECHANISM; DRUG SELECTIVITY; FEMALE; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TUMOR BIOPSY; TUMOR XENOGRAFT; ANIMAL; CANCER TRANSPLANTATION; DRUG ANTAGONISM; DRUG EFFECT; FEASIBILITY STUDY; GENE EXPRESSION PROFILING; METABOLISM; METHODOLOGY; NUDE MOUSE; TUMOR CELL LINE; XENOGRAFT;

ANIMALIA;

ANIMALS; BIOLOGICAL MARKERS; CADHERINS; CELL LINE, TUMOR; COLONIC NEOPLASMS; ENZYME INHIBITORS; FEASIBILITY STUDIES; FEMALE; GENE EXPRESSION PROFILING; HUMANS; IMMUNOHISTOCHEMISTRY; INDOLES; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; PYRROLES; RECEPTOR PROTEIN-TYROSINE KINASES; TRANSPLANTATION, HETEROLOGOUS;

EID: 1542426623     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1207268     Document Type: Article

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