Responses and Signaling Pathways in Human Optic Nerve Head Astrocytes Exposed to Hydrostatic Pressure In Vitro

GLIA

Volumn 45, Issue 4, 2004, Pages 364-377

  Salvador Silva, Mercedes ^b   Aoi, Shun ^b   Parker, Amy ^b   Yang, Ping ^b   Pecen, Paula ^b   Hernandez, M Rosario ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NONE

Author keywords

Astrocytes; Hydrostatic pressure; Optic nerve head; Signal transduction

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; 6,7 DIMETHYL 2 PHENYLQUINOXALINE; ALPHA TUBULIN; BROXURIDINE; EPIDERMAL GROWTH FACTOR RECEPTOR; FLUOROURACIL; GENISTEIN; TYRPHOSTIN;

ARTICLE; ASTROCYTE; CELL FREE SYSTEM; CELL MIGRATION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; HUMAN; HUMAN CELL; HYDROSTATIC PRESSURE; INTERMEDIATE FILAMENT; MECHANICAL STRESS; MONOLAYER CULTURE; NERVOUS SYSTEM INJURY; OPTIC NERVE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; STIMULUS RESPONSE;

ADOLESCENT; ADULT; ASTROCYTES; CELL MOVEMENT; CELLS, CULTURED; ENZYME INHIBITORS; HUMANS; HYDROSTATIC PRESSURE; MIDDLE AGED; OPTIC NERVE; SIGNAL TRANSDUCTION;

EID: 1542410190     PISSN: 08941491     EISSN: None     Source Type: Journal    
DOI: 10.1002/glia.10342     Document Type: Article

References (59)

1. Abe K, Saito H. 1999. Astrocyte stellation induced by tyrosine kinase inhibitors in culture. Brain Res 837:306-308.
2. Acevedo AD, Bowser SS, Gerritsen ME, Bizios R. 1993. Morphological and proliferative responses of endothelial cells to hydrostatic pressure: role of fibroblast growth factor. J Cell Physiol 157:603-614.
3. Agapova OA, Ricard CS, Salvador-Silva M, Hernandez MR. 2001. Expression of matrix metalloproteinases and tissue inhibitors of metalloproteinases in human optic nerve head astrocytes. Glia 33:205-216.
4. Apodaca G. 2002. Modulation of membrane traffic by mechanical stimuli. Am J Physiol Renal Physiol 282:F179-F190.
5. Bellezza AJ, Hart RT, Burgoyne CF. 2000. The optic nerve head as a biomechanical structure: initial finite element modeling. Invest Ophthalmol Vis Sci 41:2991-3000.
6. Bowman CL, Ding JP, Sachs F, Sokabe M. 1992. Mechanotransducing ion channels in astrocytes. Brain Res 584:272-286.
7. Brambilla R, Burnstock G, Bonazzi A, Ceruti S, Cattabeni F, Abbracchio MP. 1999. Cyclo-oxygenase-2 mediates P2Y receptor-induced reactive astrogliosis. Br J Pharmacol 126:563-567.
8. Buonanno A, Fischbach GD. 2001. Neuregulin and ErbB receptor signaling pathways in the nervous system. Curr Opin Neurobiol 11:287-296.
9. Caric D, Raphael H, Viti J, Feathers A, Wancio D, Lillien L. 2001. EGFRs mediate chemotactic migration in the developing telencephalon. Development 128:4203-4216.
10. Charras GT, Horton MA. 2002. Determination of cellular strains by combined atomic force microscopy and finite element modeling. Biophys J 83:858-879.
11. Dongqi H, Zeqin R. 1999. A biomathematical model for pressure-dependent lamina cribrosa behavior. J Biomech 32:579-584.
12. Eddleston M, Mucke L. 1993. Molecular profile of reactive astrocytes - implications for their role in neurologic disease. Neuroscience 54:15-36.
13. Edwards ME, Good TA. 2001. Use of a mathematical model to estimate stress and strain during elevated pressure induced lamina cribrosa deformation. Curr Eye Res 23:215-225.
14. Elkington AR, Inman CB, Steart PV, Weller RO. 1990. The structure of the lamina cribrosa of the human eye: an immunocytochemical and electron microscopical study. Eye 4:42-57.
15. Etienne-Manneville S, Hall A. 2001. Integrin-mediated activation of Cdc42 controls cell polarity in migrating astrocytes through PKC-zeta. Cell 106:489-498.
16. ffrench-Constant C, Miller RH, Burne JF, Raff MC. 1988. Evidence that migratory oligodendrocyte-type-2 astrocyte (O-2A) progenitor cells are kept out of the rat retina by a barrier at the eye-end of the optic nerve. J Neurocytol 17:13-25.
17. Govoni S, Masoero E, Favalli L, Rozza A, Scelsi R, Viappiani S, Buccellati C, Sala A, Folco G. 2001. The Cycloxygenase-2 inhibitor SC58236 is neuroprotective in an in vivo model of focal ischemia in the rat. Neurosci Lett 303:91-94.
18. Haberstroh KM, Kaefer M, Retik AB, Freeman MR, Bizios R. 1999. The effects of sustained hydrostatic pressure on select bladder smooth muscle cell functions. J Urol 162:2114-2118.
19. Hatten ME, Liem RK, Shelanski ML, Mason CA. 1991. Astroglia in CNS injury. Glia 4:233-243.
20. Hernandez MR, Pena JD, Selvidge JA, Salvador-Silva M, Yang P. 2000. Hydrostatic pressure stimulates synthesis of elastin in cultured optic nerve head astrocytes. Glia 32:122-136.
21. Hernandez MR, Agapova OA, Yang P, Salvador-Silva M, Ricard CS, Aoi S. 2002. Differential gene expression in astrocytes from human normal and glaucomatous optic nerve head analyzed by cDNA microarray. Glia 38:45-64.
22. Hirst WD, Young KA, Newton R, Allport VC, Marriott DR, Wilkin GP. 1999. Expression of COX-2 by normal and reactive astrocytes in the adult rat central nervous system. Mol Cell Neurosci 13:57-68.
23. Jimenez C, Portela RA, Mellado M, Rodriguez-Frade JM, Collard J, Serrano A, Martinez A, Avila J, Carrera AC. 2000. Role of the PI3K regulatory subunit in the control of actin organization and cell migration. J Cell Biol 151:249-262.
24. Jumblatt MM, Neufeld AH. 1986. A tissue culture assay of corneal epithelial wound closure. Invest Ophthalmol Vis Sci 27:8-13.
25. Kobayashi S, Vidal I, Pena JD, Hernandez MR. 1997. Expression of neural cell adhesion molecule (NCAM) characterizes a subpopulation of type 1 astrocytes in human optic nerve head. Glia 20:262-273.
26. Lehoux S, Tedgui A. 1998. Signal transduction of mechanical stresses in the vascular wall. Hypertension 32:338-345.
27. Liu B, Neufeld AH. 2001. Nitric oxide synthase-2 in human optic nerve head astrocytes induced by elevated pressure in vitro. Arch Ophthalmol 119:240-245.
28. Macdonald AG, Fraser PJ. 1999. The transduction of very small hydrostatic pressures. Comp Biochem Physiol A Mol Integr Physiol 122:13-36.
29. Mandell JW, Gocan NC, VandenBerg SR. 2001. Mechanical trauma induces rapid astroglial activation of ERK/MAP kinase: evidence for a paracrine signal. Glia 34:283-295.
30. McCormack SA, Viar MJ, Johnson LR. 1992. Migration of IEC-6 cells: a model for mucosal healing. Am J Physiol 263:G426-G435.
31. Mi H, Barres DA. 1999. Purification and characterization of astrocyte precursor cells in the developing rat optic nerve. J Neurosci 19:283-95.
32. Morgan WH, Yu DY, Cooper RL, Alder VA, Cringle SJ, Constable IJ. 1995. The influence of cerebrospinal fluid pressure on the lamina cribrosa tissue pressure gradient. Invest Ophthalmol Vis Sci 36:1163-1172.
33. Morgan WH, Yu DY, Alder VA, Cringle SJ, Cooper RL, House PH, Constable IJ. 1998. The correlation between cerebrospinal fluid pressure and retrolaminar tissue pressure. Invest Ophthalmol Vis Sci 39:1419-1428.
34. Morrison JC, Dorman-Pease ME, Dunkelberger GR, Quigley HA. 1990. Optic nerve head extracellular matrix in primary optic atrophy and experimental glaucoma. Arch Ophthalmol 108:1020-1024.
35. Neufeld AH, Liu B. 2003. Comparison of the signal transduction pathway for the induction of gene expression of nitric oxide synthase-2 in response to two different stimuli. Nitric Oxide 8:95-102.
36. Oishi Y, Uezono Y, Yanagihara N, Izumi F, Nakamura T, Suzuki K. 1998. Transmural compression-induced proliferation and DNA synthesis through activation of a tyrosine kinase pathway in rat astrocytoma RCR-1 cells. Brain Res 19:781:159-166.
37. Partik G, Hochegger K, Schorkhuber M, Marian B. 1999. Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro. J Cancer Res Clin Oncol 125:379-388.
38. 3 integrin engagement. Biochem Biophys Res Commun 20:297:261.
39. Pena JD, Agapova O, Gabelt BT, Levin LA, Lucarelli MJ, Kaufman PL, Hernandez MR. 2001. Increased elastin expression in astrocytes of the lamina cribrosa in response to elevated intraocular pressure. Invest Ophthalmol Vis Sci 42:2303-2314.
40. Perry VH, Lund RD. 1990. Evidence that the lamina cribrosa prevents intraretinal myelination of retinal ganglion cell axons. J Neurocytol 19:265-272.
41. Quigley HA, Dorman-Pease ME, Brown AE. 1991. Quantitative study of collagen and elastin of the optic nerve head and sclera in human and experimental monkey glaucoma. Curr Eye Res 10:877-888.
42. Ricard CS, Kobayashi S, Pena JD, Salvador-Silva M, Agapova O, Hernandez MR. 2000. Selective expression of neural cell adhesion molecule (NCAM)-180 in optic nerve head astrocytes exposed to elevated hydrostatic pressure in vitro. Brain Res Mol Brain Res 81:62-79.
43. Ridet JL, Malhotra SK, Privat A, Gage FH. 1997. Reactive astrocytes: cellular and molecular cues to biological function. Trends Neurosci 20:570-577.
44. Salvador-Silva M, Ricard CS, Agapova OA, Yang P, Hernandez MR. 2001. Expression of small heat shock proteins and intermediate filaments in the human optic nerve head astrocytes exposed to elevated hydrostatic pressure in vitro. J Neurosci Res 66:59-73.
45. Schmidt MH, Furnari FB, Cavenee WK, Bogler O. 2003. Epidermal growth factor receptor signaling intensity determines intracellular protein interactions, ubiquitination, and internalization. Proc Natl Acad Sci USA 100:6505-6510.
46. Teather LA, Wurtman RJ. 2003. Cyclooxygenase-2 mediates platelet-activating factor-induced prostaglandin E2 release from rat primary astrocytes. Neurosci Lett 340:177-180.
47. Tezel G, Wax MB. 2000. Increased production of tumor necrosis factor-alpha by glial cells exposed to simulated ischemia or elevated hydrostatic pressure induces apoptosis in cocultured retinal ganglion cells. J Neurosci 20:8693-8700.
48. Tezel G, Hernandez MR, Wax MB. 2001. In vitro evaluation of reactive astrocyte migration, a component of tissue remodeling in glaucomatous optic nerve head. Glia 34:178-189.
49. Trivino A, Ramirez JM, Salazar JJ, Ramirez AI, Garcia-Sanchez J. 1996. Immunohistochemical study of human optic nerve head astroglia. Vision Res 36:2015-2028.
50. Van Horn DL, Hyndiuk RA. 1975. Endothelial wound repair in primate cornea. Exp Eye Res 21:113-124.
51. Varela HJ, Hernandez MR. 1997. Astrocyte responses in human optic nerve head with primary open-angle glaucoma. J Glaucoma 6:303-313.
52. Verstraeten TC, Buzney SM, Macdonald SG, Neufeld AH. 1990. Retinal pigment epithelium wound closure in vitro. Pharmacologic inhibition. Invest Ophthalmol Vis Sci 31:481-488.
53. Wax MB, Tezel G, Kobayashi S, Hernandez MR. 2000. Responses of different cell lines from ocular tissues to elevated hydrostatic pressure. Br J Ophthalmol 84:423-428.
54. Wells A. 1999. EGF receptor. Int J Biochem Cell Biol 31:637-643.
55. Wright MO, Stockwell RA, Nuki G. 1992. Response of plasma membrane to applied hydrostatic pressure in chondrocytes and fibroblasts. Connect Tissue Res 28:49-70.
56. Yan DB, Coloma FM, Metheetrairut A, Trope GE, Heathcote JG, Ethier CR. 1994. Deformation of the lamina cribrosa by elevated intraocular pressure. Br J Ophthalmol 78:643-648.
57. Yarden Y, Sliwkowski M. 2001. Untangling the ErbB signalling network. Nature 2:127-137.
58. Ye H, Hernandez MR. 1995. Heterogeneity of astrocytes in human optic nerve head. J Comp Neurol 362:441-452.
59. Zhang FX, Hutchins JB. 1997. Protein phosphorylation in response to PDGF stimulation in cultured neurons and astrocytes. Brain Res Dev Brain Res 99:216-225.