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Volumn 125, Issue 7, 1999, Pages 379-388

Inhibition of epidermal-growth-factor-receptor-dependent signalling by tyrphostins A25 and AG1478 blocks growth and induces apoptosis in colorectal tumor cells in vitro

Author keywords

Apoptosis; Colon cancer; EGF receptor signalling; Tyrphostin

Indexed keywords

3,4 DIHYDROXYBENZYLIDENE MALONONITRILE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZINOLINE; 4 (3 CHLOROANILINO) 6,7 DIMETHOXYQUINAZOLINE; A 25; ANTINEOPLASTIC AGENT; EPIDERMAL GROWTH FACTOR RECEPTOR; TYRPHOSTIN; UNCLASSIFIED DRUG;

EID: 0033037775     PISSN: 01715216     EISSN: None     Source Type: Journal    
DOI: 10.1007/s004320050290     Document Type: Article
Times cited : (48)

References (41)
  • 1
    • 0029074441 scopus 로고
    • Role of apoptosis in modulation of the growth of human colorectal tubular and villous adenomas
    • Arai T, Kino I (1995) Role of apoptosis in modulation of the growth of human colorectal tubular and villous adenomas. J Pathol 176:37-44
    • (1995) J Pathol , vol.176 , pp. 37-44
    • Arai, T.1    Kino, I.2
  • 2
    • 0024584595 scopus 로고
    • The occurrence of epidermal growth factor receptors and the characterization of EGF-like factors in human ovarian, endometrial, cervical and breast cancer. EGF receptors and factors in gynecological carcinomas
    • Bauknecht T, Kohler M, Janz I, Pfleiderer A (1989) The occurrence of epidermal growth factor receptors and the characterization of EGF-like factors in human ovarian, endometrial, cervical and breast cancer. EGF receptors and factors in gynecological carcinomas. J Cancer Res Clin Oncol 115:193-199
    • (1989) J Cancer Res Clin Oncol , vol.115 , pp. 193-199
    • Bauknecht, T.1    Kohler, M.2    Janz, I.3    Pfleiderer, A.4
  • 4
    • 0022550599 scopus 로고
    • Production of transforming growth factors by human colon cancer cell lines
    • Coffey RJ, Shipley GD, Moses HL (1986) Production of transforming growth factors by human colon cancer cell lines. Cancer Res 46:1164-1169
    • (1986) Cancer Res , vol.46 , pp. 1164-1169
    • Coffey, R.J.1    Shipley, G.D.2    Moses, H.L.3
  • 5
    • 0026880092 scopus 로고
    • Differential regulation of transforming growth factor alpha autoinduction in a nontransformed and transformed epithelial cell
    • Coffey RJ Jr, Graves Deal R, Dempsey PJ, Whitehead RH, Pittelkow MR (1992) Differential regulation of transforming growth factor alpha autoinduction in a nontransformed and transformed epithelial cell. Cell Growth Differ 3:347-354
    • (1992) Cell Growth Differ , vol.3 , pp. 347-354
    • Coffey R.J., Jr.1    Graves Deal, R.2    Dempsey, P.J.3    Whitehead, R.H.4    Pittelkow, M.R.5
  • 6
    • 0026520472 scopus 로고
    • The physiology of transforming growth factor alpha
    • Vande Woude GF, Klein G (eds), Acad. Press, San Diego
    • Dernyck R (1992) The physiology of transforming growth factor alpha. In: Vande Woude GF, Klein G (eds) Adv Cancer Res, vol 58, Acad. Press, San Diego, pp 27-52
    • (1992) Adv Cancer Res , vol.58 , pp. 27-52
    • Dernyck, R.1
  • 7
    • 0024355092 scopus 로고
    • Autocrine interaction between TGF alpha and the EGF-receptor: Quantitative requirements for induction of the malignant phenotype
    • Di Marco E, Pierce JH, Fleming TP, Kraus MH, Molloy CJ, Aaronson SA, Di Fiore PP (1989) Autocrine interaction between TGF alpha and the EGF-receptor: quantitative requirements for induction of the malignant phenotype. Oncogene 4:831-838
    • (1989) Oncogene , vol.4 , pp. 831-838
    • Di Marco, E.1    Pierce, J.H.2    Fleming, T.P.3    Kraus, M.H.4    Molloy, C.J.5    Aaronson, S.A.6    Di Fiore, P.P.7
  • 8
    • 0026325285 scopus 로고
    • Rapid uptake of tyrphostin into A431 human epidermoid cells is followed by delayed inhibition of epidermal growth factor (EGF)-stimulated EGF receptor tyrosine kinase activity
    • Faaland CA, Mermelstein FH, Hayoshi J, Laskin JD (1991) Rapid uptake of tyrphostin into A431 human epidermoid cells is followed by delayed inhibition of epidermal growth factor (EGF)-stimulated EGF receptor tyrosine kinase activity. Mol Cell Biol 11:2697-2703
    • (1991) Mol Cell Biol , vol.11 , pp. 2697-2703
    • Faaland, C.A.1    Mermelstein, F.H.2    Hayoshi, J.3    Laskin, J.D.4
  • 9
    • 0025654204 scopus 로고
    • Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation
    • Hafez MM, Infante D, Winawer S, Friedman E (1990) Transforming growth factor beta 1 acts as an autocrine-negative growth regulator in colon enterocytic differentiation but not in goblet cell maturation. Cell Growth Differ 1:617-626
    • (1990) Cell Growth Differ , vol.1 , pp. 617-626
    • Hafez, M.M.1    Infante, D.2    Winawer, S.3    Friedman, E.4
  • 10
    • 0027485599 scopus 로고
    • Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: Implications for the possible role of dietary fibre in the prevention of large-bowel cancer
    • Hague A, Manning AM, Hanlon KA, Huschtscha LI, Hart D, Paraskeva C (1993) Sodium butyrate induces apoptosis in human colonic tumour cell lines in a p53-independent pathway: implications for the possible role of dietary fibre in the prevention of large-bowel cancer. Int J Cancer 55:498-505
    • (1993) Int J Cancer , vol.55 , pp. 498-505
    • Hague, A.1    Manning, A.M.2    Hanlon, K.A.3    Huschtscha, L.I.4    Hart, D.5    Paraskeva, C.6
  • 11
    • 0029692479 scopus 로고    scopus 로고
    • The role of the insulin-like growth factor system in human cancer
    • Vande Woude GF, Klein G (eds). Acad. Press, San Diego
    • Haim W, LeRoith D (1996) The role of the insulin-like growth factor system in human cancer. In: Vande Woude GF, Klein G (eds) Adv Cancer Res, Vol. 68. Acad. Press, San Diego, pp 183-223
    • (1996) Adv Cancer Res , vol.68 , pp. 183-223
    • Haim, W.1    LeRoith, D.2
  • 12
    • 0026549434 scopus 로고
    • Autonomous proliferation of colon carcinoma cells that co-express transforming growth factor alpha and its receptor: Variable effect of receptor-blocking antibody
    • Karnes WE jr, Walsh JH, Wu SV, Kim RS, Martin MG, Wong HC, Mendelsohn J, Park J-G, Cuttitta F (1992) Autonomous proliferation of colon carcinoma cells that co-express transforming growth factor alpha and its receptor: variable effect of receptor-blocking antibody. Gastroenterology 102:474-485
    • (1992) Gastroenterology , vol.102 , pp. 474-485
    • Karnes W.E., Jr.1    Walsh, J.H.2    Wu, S.V.3    Kim, R.S.4    Martin, M.G.5    Wong, H.C.6    Mendelsohn, J.7    Park, J.-G.8    Cuttitta, F.9
  • 14
    • 0028036895 scopus 로고
    • Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2
    • Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG, Reed JC (1994) Immunohistochemical determination of in vivo distribution of Bax, a dominant inhibitor of Bcl-2. Am J Pathol 145:1323-1336
    • (1994) Am J Pathol , vol.145 , pp. 1323-1336
    • Krajewski, S.1    Krajewska, M.2    Shabaik, A.3    Miyashita, T.4    Wang, H.G.5    Reed, J.C.6
  • 15
    • 0029043811 scopus 로고
    • Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo
    • Krajewski S, Bodrug S, Krajewska M, Shabaik A, Gascoyne R, Berean K, Reed JC (1995) Immunohistochemical analysis of Mcl-1 protein in human tissues. Differential regulation of Mcl-1 and Bcl-2 protein production suggests a unique role for Mcl-1 in control of programmed cell death in vivo. Am J Pathol 146:1309-1319
    • (1995) Am J Pathol , vol.146 , pp. 1309-1319
    • Krajewski, S.1    Bodrug, S.2    Krajewska, M.3    Shabaik, A.4    Gascoyne, R.5    Berean, K.6    Reed, J.C.7
  • 16
    • 0029990550 scopus 로고    scopus 로고
    • Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family
    • Krajewski S, Krajewska M, Reed JC (1996) Immunohistochemical analysis of in vivo patterns of Bak expression, a proapoptotic member of the Bcl-2 protein family. Cancer Res 56:2849-2855
    • (1996) Cancer Res , vol.56 , pp. 2849-2855
    • Krajewski, S.1    Krajewska, M.2    Reed, J.C.3
  • 18
    • 0028968949 scopus 로고
    • Tyrosine kinase inhibition: An approach to drug development
    • Levitzki A, Gazit A (1995) Tyrosine kinase inhibition: an approach to drug development. Science 267:1782-1788
    • (1995) Science , vol.267 , pp. 1782-1788
    • Levitzki, A.1    Gazit, A.2
  • 19
    • 0024474695 scopus 로고
    • Tyrosine phosphorylation of a Mr 63,000 protein induced by an endogenous mitogen in human colon carcinoma cells, but not in normal colonocytes
    • Marian B, Winawer S, Friedman E (1989) Tyrosine phosphorylation of a Mr 63,000 protein induced by an endogenous mitogen in human colon carcinoma cells, but not in normal colonocytes. Cancer Res 49:4231-4236
    • (1989) Cancer Res , vol.49 , pp. 4231-4236
    • Marian, B.1    Winawer, S.2    Friedman, E.3
  • 20
    • 0025368610 scopus 로고
    • Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium
    • Markowitz SD, Molkentin K, Gerbic C, Jackson J, Stellato T, Willson JK (1990) Growth stimulation by coexpression of transforming growth factor-alpha and epidermal growth factor-receptor in normal and adenomatous human colon epithelium. J Clin Invest 86:356-362
    • (1990) J Clin Invest , vol.86 , pp. 356-362
    • Markowitz, S.D.1    Molkentin, K.2    Gerbic, C.3    Jackson, J.4    Stellato, T.5    Willson, J.K.6
  • 21
    • 0022999284 scopus 로고
    • Mechanism of antitumor activity in mice for anti-epidermal growth factor receptor monoclonal antibodies with different isotypes
    • Masui H, Moroyama T, Mendelsohn J (1986) Mechanism of antitumor activity in mice for anti-epidermal growth factor receptor monoclonal antibodies with different isotypes. Cancer Res 46:5592-5598
    • (1986) Cancer Res , vol.46 , pp. 5592-5598
    • Masui, H.1    Moroyama, T.2    Mendelsohn, J.3
  • 22
    • 0026436895 scopus 로고
    • Epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies
    • Mendelsohn J (1992) Epidermal growth factor receptor as a target for therapy with antireceptor monoclonal antibodies. J Natl Cancer Inst Monogr 13:125-131
    • (1992) J Natl Cancer Inst Monogr , vol.13 , pp. 125-131
    • Mendelsohn, J.1
  • 25
    • 0028171075 scopus 로고
    • Epidermal-growth-factor-dependent activation of the src-family kinases
    • Osherov N, Levitzki A (1994) Epidermal-growth-factor-dependent activation of the src-family kinases. Eur J Biochem 225:1047-1053
    • (1994) Eur J Biochem , vol.225 , pp. 1047-1053
    • Osherov, N.1    Levitzki, A.2
  • 26
    • 0027198702 scopus 로고
    • Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins
    • Osherov N, Gazit A, Gilon C, Levitzki A (1993) Selective inhibition of the epidermal growth factor and HER2/neu receptors by tyrphostins. J Biol Chem 268:11134-11142
    • (1993) J Biol Chem , vol.268 , pp. 11134-11142
    • Osherov, N.1    Gazit, A.2    Gilon, C.3    Levitzki, A.4
  • 27
    • 0031802471 scopus 로고    scopus 로고
    • Apoptosis in human colorectal tumours: Ultrastructure and quantitative studies on tissue localization and association with bak expression
    • Partik G, KahlRainer P, Sedivy R, Ellinger A, Bursch W, Marian B (1998) Apoptosis in human colorectal tumours: ultrastructure and quantitative studies on tissue localization and association with bak expression. Virchows Archiv an International Journal Of Pathology 432 (5):415-426
    • (1998) Virchows Archiv an International Journal of Pathology , vol.432 , Issue.5 , pp. 415-426
    • Partik, G.1    KahlRainer, P.2    Sedivy, R.3    Ellinger, A.4    Bursch, W.5    Marian, B.6
  • 28
    • 0024321324 scopus 로고
    • Binding of epidermal growth factor and insulin-like growth-factor I in renal carcinoma and adjacent normal kidney tissue
    • Pekonen F, Partanen S, Rutanen EM (1989) Binding of epidermal growth factor and insulin-like growth-factor I in renal carcinoma and adjacent normal kidney tissue. Int J Cancer 43:1029-1033
    • (1989) Int J Cancer , vol.43 , pp. 1029-1033
    • Pekonen, F.1    Partanen, S.2    Rutanen, E.M.3
  • 29
    • 0028280238 scopus 로고
    • The degree of inhibition of protein tyrosine kinase activity by tyrphostin 23 and 25 is related to their instability
    • Ramdas L, McMurray JS, Budde RJ (1994) The degree of inhibition of protein tyrosine kinase activity by tyrphostin 23 and 25 is related to their instability. Cancer Res 54:867-869
    • (1994) Cancer Res , vol.54 , pp. 867-869
    • Ramdas, L.1    McMurray, J.S.2    Budde, R.J.3
  • 32
    • 10244235304 scopus 로고    scopus 로고
    • Protein kinase C beta 1 and protein kinase C beta 2 activate p57 mitogen-activated protein kinase and block differentiation in colon carcinoma cells
    • Sauma S, Yan Z, Ohno S, Friedman E (1996) Protein kinase C beta 1 and protein kinase C beta 2 activate p57 mitogen-activated protein kinase and block differentiation in colon carcinoma cells. Cell Growth Differ 7:587-594
    • (1996) Cell Growth Differ , vol.7 , pp. 587-594
    • Sauma, S.1    Yan, Z.2    Ohno, S.3    Friedman, E.4
  • 33
    • 0023686033 scopus 로고
    • Signal transduction by allosteric receptor oligomerization
    • Schlessinger J (1988) Signal transduction by allosteric receptor oligomerization. Trends Biochem Sci 13:443-447
    • (1988) Trends Biochem Sci , vol.13 , pp. 443-447
    • Schlessinger, J.1
  • 35
    • 0019320348 scopus 로고
    • Autocrine secretion and malignant transformation of cells
    • Sporn MB, Todaro GJ (1980) Autocrine secretion and malignant transformation of cells. N Engl J Med 303:878-880
    • (1980) N Engl J Med , vol.303 , pp. 878-880
    • Sporn, M.B.1    Todaro, G.J.2
  • 36
    • 0030070626 scopus 로고    scopus 로고
    • Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: Analysis by terminal-deoxynucleotidyl-transferase-mediated dUTP-biotin nick end labeling
    • Tatebe S, Ishida M, Kasagi N, Tsujitani S, Kaibara N, Ito H (1996) Apoptosis occurs more frequently in metastatic foci than in primary lesions of human colorectal carcinomas: analysis by terminal-deoxynucleotidyl-transferase-mediated dUTP-biotin nick end labeling. Int J Cancer 65:173-177
    • (1996) Int J Cancer , vol.65 , pp. 173-177
    • Tatebe, S.1    Ishida, M.2    Kasagi, N.3    Tsujitani, S.4    Kaibara, N.5    Ito, H.6
  • 38
    • 0023800619 scopus 로고
    • In vitro models of human colonic adenomatous polyps
    • Willson JK, Bittner GN (1988) In vitro models of human colonic adenomatous polyps. Prog Clin Biol Res 279:347-356
    • (1988) Prog Clin Biol Res , vol.279 , pp. 347-356
    • Willson, J.K.1    Bittner, G.N.2
  • 40
    • 0028969852 scopus 로고
    • Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin
    • Wu X, Fan Z, Masui H, Rosen N, Mendelsohn J (1995) Apoptosis induced by an anti-epidermal growth factor receptor monoclonal antibody in a human colorectal carcinoma cell line and its delay by insulin. J Clin Invest 95:1897-1905
    • (1995) J Clin Invest , vol.95 , pp. 1897-1905
    • Wu, X.1    Fan, Z.2    Masui, H.3    Rosen, N.4    Mendelsohn, J.5
  • 41
    • 0025736385 scopus 로고
    • Dependence of a human squamous carcinoma and associated paraneoplastic syndromes on the epidermal growth factor receptor pathway in nude mice
    • Yoneda T, Alsina MM, Watatani K, Bellot F, Schlessinger J, Mundy GR (1991) Dependence of a human squamous carcinoma and associated paraneoplastic syndromes on the epidermal growth factor receptor pathway in nude mice. Cancer Res 51:2438-2443
    • (1991) Cancer Res , vol.51 , pp. 2438-2443
    • Yoneda, T.1    Alsina, M.M.2    Watatani, K.3    Bellot, F.4    Schlessinger, J.5    Mundy, G.R.6


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