Comparison of the signal transduction pathways for the induction of gene expression of nitric oxide synthase-2 in response to two different stimuli

Nitric Oxide - Biology and Chemistry

Volumn 8, Issue 2, 2003, Pages 95-102

  Neufeld, Arthur H ^a   Liu, Bin ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Cytokines; EGF receptor tyrosine kinase; Glaucoma; NF B; p38 MAP kinase; Pressure; Promoter

Indexed keywords

4 (4 FLUOROPHENYL) 2 (4 HYDROXYPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; ENZYME; EPIDERMAL GROWTH FACTOR RECEPTOR; GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; INTERLEUKIN 1BETA; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN TYROSINE KINASE INHIBITOR; SYNAPTOPHYSIN; UNCLASSIFIED DRUG;

ADULT; ARTICLE; ASTROCYTE; CONTROLLED STUDY; DRUG EFFECT; ENZYME INDUCTION; ENZYME SYNTHESIS; GENE EXPRESSION; GENETIC TRANSCRIPTION; HUMAN; HUMAN TISSUE; HYDROSTATIC PRESSURE; OPTIC NERVE; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

EID: 0037334024     PISSN: 10898603     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1089-8603(02)00164-7     Document Type: Article

References (42)

1. Taylor B.S., Geller D.A. Molecular regulation of the human inducible nitric oxide synthase (iNOS) gene. Shock. 13:2000;413-424.
2. Rao K.M. Molecular mechanisms regulating iNOS expression in various cell types. J. Toxicol. Environ. Health B Crit. Rev. 3:2000;27-58.
3. Chu S.C., Marks-Konczalik J., Wu H.P., Banks T.C., Moss J. Analysis of the cytokine-stimulated human inducible nitric oxide synthase (iNOS) gene: characterization of differences between human and mouse iNOS promoters. Biochem. Biophys. Res. Commun. 248:1998;871-878.
4. Lorsbach R.B., Murphy W.J., Lowenstein C.J., Snyder S.H., Russell S.W. Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-γ and lipopolysaccharide. J. Biol. Chem. 268:1993;1908-1913.
5. Gosgnach W., Messika-Zeitoun D., Gonzalez W., Philipe M., Michel J.B. Shear stress induces iNOS expression in cultured smooth muscle cells: role of oxidative stress. Am. J. Physiol. Cell Physiol. 279:2000;C1880-C1888.
6. Fermor B., Weinberg J.B., Pisetsky D.S., Misukonis M.A., Banes A.J., Guilak F. The effects of static and intermittent compression on nitric oxide production in articular cartilage explants. J. Orthop. Res. 19:2001;729-737.
7. Liu B., Neufeld A.H. Nitric oxide synthase-2 in human optic nerve head astrocytes induced by elevated pressure in vitro. Arch. Ophthalmol. 119:2001;240-245.
8. Brivanlou A.H., Darnell J.E. Jr. Signal transduction and the control of gene expression. Science. 295:2002;813-818.
9. Xie Q.W., Whisnant R., Nathan C. Promoter of the mouse gene encoding calcium-independent nitric oxide synthase confers inducibility by interferon gamma and bacterial lipopolysaccharide. J. Exp. Med. 177:1993;1779-1784.
10. Lowenstein C.J., Alley E.W., Raval P., Snowman A.M., Snyder S.H., Russell S.W., Murphy W.J. Macrophage nitric oxide synthase gene: two upstream regions mediate induction by interferon gamma and lipopolysaccharide. Proc. Natl. Acad. Sci. USA. 90:1993;9730-9734.
11. Zhang H., Chen X., Teng X., Snead C., Catravas J.D. Molecular cloning and analysis of the rat inducible nitric oxide synthase gene promoter in aortic smooth muscle cells. Biochem. Pharmacol. 55:1998;1873-1880.
12. Nunokawa Y., Ishida N., Tanaka S. Promoter analysis of human inducible nitric oxide synthase gene associated with cardiovascular homeostasis. Biochem. Biophys. Res. Commun. 200:1994;802-807.
13. Ganster R.W., Taylor B.S., Shao L., Geller D.A. Complex regulation of human inducible nitric oxide synthase gene transcription by Stat 1 and NF-κB. Proc. Natl. Acad. Sci. USA. 98:2001;8638-8643.
14. Taylor B.S., de Vera M.E., Ganster R.W., Wang Q., Shapiro R.A., Morris S.M. Jr., Billiar T.R., Geller D.A. Multiple NF-κB enhancer elements regulate cytokine induction of the human inducible nitric oxide synthase gene. J. Biol. Chem. 273:1998;15148-15156.
15. Paludan S.R., Malmgaard L., Ellermann-Eriksen S., Bosca L., Mogensen S.C. Interferon (IFN)-γ and Herpes simplex virus/tumor necrosis factor-α synergistically induce nitric oxide synthase 2 in macrophages through cooperative action of nuclear factor-κB and IFN regulatory factor-1. Eur. Cytokine Netw. 12:2001;297-308.
16. Faure V., Hecquet C., Courtois Y., Goureau O. Role of interferon regulatory factor-1 and mitogen-activated protein kinase pathways in the induction of nitric oxide synthase-2 in retinal pigmented epithelial cells. J. Biol. Chem. 274:1999;4794-4800.
17. Kleinert H., Wallerath T., Fritz G., Ihrig-Biedert I., Rodriguez-Pascual F., Geller D.A., Forstermann U. Cytokine induction of NO synthase II in human DLD-1 cells: roles of the JAK-STAT, AP-1 and NF-κB-signaling pathways. Br. J. Pharmacol. 125:1998;193-201.
18. Hernandez M.R., Igoe F., Neufeld A.H. Cell culture of the human lamina cribrosa. Invest. Ophthalmol. Vis. Sci. 29:1988;78-89.
19. Gazit A., Yaish P., Gilon C., Levitzki A. Tyrphostins I: synthesis and biological activity of protein tyrosine kinase inhibitors. J. Med. Chem. 32:1989;2344-2352.
20. Lyall R.M., Zilberstein A., Gazit A., Gilon C., Levitzki A., Schlessinger J. Tyrphostins inhibit epidermal growth factor (EGF)-receptor tyrosine kinase activity in living cells and EGF-stimulated cell proliferation. J. Biol. Chem. 264:1989;14503-14509.
21. Singh R.P., Dhawan P., Golden C., Kapoor G.S., Mehta K.D. One-way cross-talk between p38(MAPK) and p42/44(MAPK). Inhibition of p38(MAPK) induces low density lipoprotein receptor expression through activation of the p42/44(MAPK) cascade. J. Biol. Chem. 274:1999;19593-19600.
22. Iwasaki S., Iguchi M., Watanabe K., Hoshino R., Tsujimoto M., Kohno M. Specific activation of the p38 mitogen-activated protein kinase signaling pathway and induction of neurite outgrowth in PC12 cells by bone morphogenetic protein-2. J. Biol. Chem. 274:1999;26503-26510.
23. Haddad J.J. Nuclear factor (NF)-κB blockade attenuates but does not abrogate LPS-mediated interleukin (IL)-1 beta biosynthesis in alveolar epithelial cells. Biochem. Biophys. Res. Commun. 293:2002;252-257.
24. Lin Y.Z., Yao S.Y., Veach R.A., Torgerson T.R., Hawiger J. Inhibition of nuclear translocation of transcription factor NF-κB by a synthetic peptide containing a cell membrane-permeable motif and nuclear localization sequence. J. Biol. Chem. 270:1995;14255-14258.
25. Kultz D., Madhany S., Burg M.B. Hyperosmolality causes growth arrest of murine kidney cells. Induction of GADD45 and GADD153 by osmosensing via stress-activated protein kinase2. J. Biol. Chem. 273:1998;13645-13651.
26. Piao Z., Ui-Tei K., Nagano M., Miyata Y. Participation of intracellular Ca(2+)/calmodulin and protein kinase(s) in the pathway of apoptosis induced by a Drosophila cell death gene, reaper. Mol. Cell Biol. Res. Commun. 4:2001;307-312.
27. Hayden M.A., Nakayama D.K. Cyclic nucleotides and inducible nitric oxide synthesis in pulmonary artery smooth muscle. J. Surg. Res. 82:1999;222-227.
28. Huang Q., Yuan Y. Interaction of PKC and NOS in signal transduction of microvascular hyperpermeability. Am. J. Physiol. 273:1997;H2442-H2451.
29. Rothwarf D.M., Karin M. The NF-κB activation pathway: a paradigm in information transfer from membrane to nucleus. Sci. STKE. 1999:1999;RE1.
30. Cheng N., Shi X., Ye J., Castranova V., Chen F., Leonard S.S., Vallyathan V., Rojanasakul Y. Role of transcription factor NF-κB in asbestos-induced TNFα response from macrophages. Exp. Mol. Pathol. 66:1999;201-210.
31. Panet H., Barzilai A., Daily D., Melamed E., Offen D. Activation of nuclear transcription factor kappa B (NF-κB) is essential for dopamine-induced apoptosis in PC12 cells. J. Neurochem. 77:2001;391-398.
32. Whitmarsh A.J., Davis R.J. Signal transduction by MAP kinases: regulation by phosphorylation-dependent switches. Sci. STKE. 1999:1999;E1.
33. Mendes A.F., Caramona M.M., Carvalho A.P., Lopes M.C. Role of mitogen-activated protein kinases and tyrosine kinases on IL-1-induced NF-κB activation and iNOS expression in bovine articular chondrocytes. Nitric Oxide. 6:2002;35-44.
34. Cruz M.T., Duarte C.B., Goncalo M., Carvalho A.P., Lopes M.C. Involvement of JAK2 and MAPK on type II nitric oxide synthase expression in skin-derived dendritic cells. Am. J. Physiol. 277:1999;C1050-C1057.
35. Kristof A.S., Marks-Konczalik J., Moss J. Mitogen-activated protein kinases mediate activator protein-1-dependent human inducible nitric-oxide synthase promoter activation. J. Biol. Chem. 276:2001;8445-8452.
36. Ajizian S.J., English B.K., Meals E.A. Specific inhibitors of p38 and extracellular signal-regulated kinase mitogen-activated protein kinase pathways block inducible nitric oxide synthase and tumor necrosis factor accumulation in murine macrophages stimulated with lipopolysaccharide and interferon-γ J. Infect. Dis. 179:1999;939-944.
37. Schlessinger J. Cell signaling by receptor tyrosine kinases. Cell. 103:2000;211-225.
38. Faure V., Courtois Y., Goureau O. Differential regulation of nitric oxide synthase-II mRNA by growth factors in rat, bovine, and human retinal pigmented epithelial cells. Ocul. Immunol. Inflamm. 7:1999;27-34.
39. Liu B., Neufeld A.H. Expression of nitric oxide synthase-2 (NOS-2) in reactive astrocytes of the human glaucomatous optic nerve head. Glia. 30:2000;178-186.
40. Tsuda T., Kusui T., Jensen R.T. Neuromedin B receptor activation causes tyrosine phosphorylation of p125FAK by a phospholipase C independent mechanism which requires p21rho and integrity of the actin cytoskeleton. Biochemistry. 36:1997;16328-16337.
41. Lin S.Y., Makino K., Xia W., Matin A., Wen Y., Kwong K.Y., Bourguignon L., Hung M.C. Nuclear localization of EGF receptor and its potential new role as a transcription factor. Nat. Cell Biol. 3:2001;802-808.
42. B. Liu, A.H. Neufeld, Activation of epidermal growth factor receptor signals induction of nitric oxide synthase-2 in human optic nerve head astrocytes in glaucomatous optic neuropathy, Neurobiology of Disease, in press.