Use of a mathematical model to estimate stress and strain during elevated pressure induced lamina cribrosa deformation

Current Eye Research

Volumn 23, Issue 3, 2001, Pages 215-225

  Edwards, Michael E ^a   Good, Theresa A ^a  

^a TEXAS A AND M UNIVERSITY   (United States)

Author keywords

Elasticity; Glaucoma; Intraocular pressure; Mathematical model

Indexed keywords

ARTICLE; ASTROCYTE; BONE DEFORMATION; CELL DAMAGE; CELL DEATH; GLAUCOMA; INTRAOCULAR PRESSURE; LAMINA CRIBROSA DEFORMATION; MATHEMATICAL MODEL; NERVE DEGENERATION; OPTIC NERVE; PARAMETER; PRIORITY JOURNAL; RETINA GANGLION CELL; SHEAR STRESS; STRESS STRAIN RELATIONSHIP;

BIOMECHANICS; GLAUCOMA; HUMANS; INTRAOCULAR PRESSURE; MODELS, BIOLOGICAL; MODELS, THEORETICAL; OCULAR HYPERTENSION; OPTIC DISK; OPTIC NERVE DISEASES; STRESS;

EID: 0036251728     PISSN: 02713683     EISSN: None     Source Type: Journal    
DOI: 10.1076/ceyr.23.3.215.5460     Document Type: Article

References (41)

1. Mechanisms of optic nerve damage in primary open-angle glaucoma
2. Axial length and scleral thickness effect on susceptibility of glaucomatous damage: A theoretical model implementing LaPlace's Law
3. Displacement of optic nerve head in response to short-term intraocular pressure elevation in human eyes
4. Deformation of the lamina cribrosa by elevated intraocular pressure
5. Comparison of a noninvasive measurement of optic nervehead mechanical compliance with an invasive method
6. Responses of different cell lines from ocular tissues to elevated hydrostatic pressure
7. The optic nerve head in glaucoma: Role of astrocytes in tissue remodeling
8. Effects of stress and strain on retinal glial cells: Implications for glaucoma
9. Displacement of the optic nerve head by acute changes in intraocular pressure in monkey eyes
10. Morphological changes in the lamina cribrosa correlated with neural loss in open-angle glaucoma
11. i in NG108-15 cells subjected to high strain rate deformation and chemical hypoxia: An in vitro model for neural trauma
12. A new model for rapid stretch-induced injury of cells in culture: Characterization of the model using astrocytes
13. An in vitro traumatic injury model to examine the response of neurons to a hydrodynamically-induced deformation
14. A qualitative and quantitative analysis of the response of the retinal ganglion cell soma after stretch injury to the adult guinea-pig optic nerve
15. 2+ on in vitro astrocyte injury
16. Alterations in phosphatidylcholine metabolism of stretch-injured cultured rat astrocytes
17. An in vitro model of traumatic neuronal injury: Loading rate-dependent changes in acute cytosolic calcium and lactate dehydrogenase release
18. Axonal cytoskeletal changes after non-disruptive axonal injury
19. Development of an in vitro model of glaucoma: Examining the effects of stress and strain on cells of the central nervous system
20. Pulsatile shear stress leads to DNA fragmentation in human SH-SY5Y neuroblastoma cell line
21. A biomathematical model for pressure dependent lamina cribrosa behavior
22. Glaucoma hypothesis: Application of the law of LaPlace
23. Glaucoma: Changes in extracellular matrix in the optic nerve head
24. Mathematical modeling of the elastic properties of retina: A determination of Young's modulus
25. Nonlinear material properties of the intact cornea and sclera
26. Measurements of the compressive properties of scleral tissue
27. Bending of circular plates with large deflections
28. Mechanical behavior of the sclera
29. Causes of optic nerve damage in glaucoma
30. The retained elasticity of elastin under fixation agents
31. The lamina cribrosa in normal and glaucomatous human eyes
32. Regional differences in the structure of the lamina cribrosa and their relation to glaucomatous optic nerve damage
33. The size and shape of the optic disc in normal human eyes
34. The optic nerve head as a biomechanical structure: Initial finite element modeling
35. The glaucomatous visual field
36. The organization of nerve fibre bundles in primate optic nerve head
37. Optic disk size in open angle glaucoma: The Blue Mountains Eye Study
38. The relationship between optic disc area and open angle glaucoma: The Baltimore Eye Survey