Regulation of dopamine D1 receptor trafficking by protein kinase A-dependent phosphorylation

Molecular Pharmacology

Volumn 61, Issue 4, 2002, Pages 806-816

  Mason, John N ^a   Kozell, Laura B ^a   Neve, Kim A ^b  

^a PORTLAND VA MEDICAL CENTER   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

6 CHLORO 2,3,4,5 TETRAHYDRO 7,8 DIHYDROXY 1 PHENYL 1H 3 BENZAZEPINE; 8 CHLORO 2,3,4,5 TETRAHYDRO 3 METHYL 5 PHENYL 1H 3 BENZAZEPIN 7 OL HYDROGEN MALEATE; ALANINE; BUTACLAMOL; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; DOPAMINE; DOPAMINE 1 RECEPTOR; DOPAMINE 1 RECEPTOR STIMULATING AGENT; DOPAMINE 2 RECEPTOR BLOCKING AGENT; GREEN FLUORESCENT PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; POLYHISTIDINE; SERINE; THREONINE;

AMINO ACID SUBSTITUTION; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BINDING AFFINITY; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL NUCLEUS; CONTROLLED STUDY; ENZYME INHIBITION; GENE MUTATION; INTERNALIZATION; MOUSE; NEUROBLASTOMA CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PROTEIN TARGETING; RECEPTOR SENSITIVITY;

AMINO ACID SEQUENCE; BIOLOGICAL TRANSPORT; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DOPAMINE AGONISTS; ENDOCYTOSIS; GREEN FLUORESCENT PROTEINS; HUMANS; LUMINESCENT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHORYLATION; PROTEIN CONFORMATION; RECEPTORS, DOPAMINE D1; TUMOR CELLS, CULTURED;

EID: 0036211021     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.61.4.806     Document Type: Article

References (43)

1. Neurotransmitter synthesis by neuroblastoma clones
2. 1A dopamine receptor staining
3. Threonine phosphorylation diverts internalized epidermal growth factor receptors from a degradative pathway to the recycling endosome
4. 1-dopamine receptors linked to adenylyl cyclase activity in cultured NS20Y neuroblastoma cells
5. Beta-adrenergic kinase: Identification of a novel protein kinase that phosphorylates the agonistoccupied form of the receptor
6. Identification of a specific site required for rapid heterologous desensitization of the β-adrenergic receptor by cAMP-dependent protein kinase
7. Regulation and functional characterization of a rat recombinant dopamine D3 receptor
8. Reinsertion or degradation of AMPA receptors determined by activity-dependent endocytic sorting
9. 1 dopamine receptor function: Evidence for a novel pathway for receptor dephosphorylation
10. Agonist-induced desensitization of the β-adrenergic receptorlinked adenylate cyclase
11. 2-adrenergic receptor are involved in distinct pathways of receptor desensitization
12. Turning off the signal: Desensitization of β-adrenergic receptor function
13. 1 dopamine receptors with mutations of protein kinase phosphorylation sites: Attenuation of the rate of agonist-induced desensitization
14. Consensus sequences as substrate specificity determinants for protein kinases and protein phosphatases
15. Amino and carboxyl terminal modifications to facilitate the production and purification of a G protein-coupled receptor
16. Intracellular trafficking of the muscarinic acetylcholine receptor: Importance of subtype and cell type
17. The role of receptor kinases and arrestins in G protein-coupled receptor regulation
18. 1A dopamine receptor: Efficacy in causing desensitization dissociates from both receptor occupancy and functional potency
19. Molecular cloning and expression of the rhesus macaque D1 dopamine receptor gene
20. Identification of phosphorylation sites in the G protein-coupled receptor for parathyroid hormone. Receptor phosphorylation is not required for agonist-induced internalization
21. Membrane trafficking regulates the activity of the human dopamine transporter
22. Agonist-induced subsensitivity of adenylate cyclase coupled with a dopamine receptor in slices from rat corpus striatum
23. 2-adrenergic receptor regulates the synergistic action of cyclic AMP-dependent protein kinase and β-adrenergic receptor kinase involved in its phosphorylation and desensitization
24. Advanced mammalian gene transfer: High titre retroviral vectors with multiple drug selection markers and a complementary helper-free packaging cell line
25. Endocytosis
26. Pivotal role for aspartate-80 in the regulation of D2 receptor affinity for drugs and inhibition of adenylyl cyclase
27. 1 receptor
28. Agonist-induced desensitization of dopamine D1 receptor-stimulated adenylyl cyclase activity is temporally and biochemically separated from D1 receptor internalization
29. 1A angiotensin receptor
30. 2-adrenergic receptors permit receptor resensitization
31. 2-adrenergic receptor pathway in S49 lymphoma cells
32. Dual pathways of internalization of cholecystokinin receptor
33. Processing and ligand-induced modifications of the V2 vasopressin receptor
34. 2-adrenergic receptors
35. Regulation of dopamine receptor function and expression
36. Differential regulation of dopamine D1A receptor responsiveness by various G protein-coupled receptor kinases
37. Role of endocytosis in mediating downregulation of G-protein-coupled receptors
38. 1 dopamine receptor in mutant Chinese hamster ovary cells deficient in cyclic AMP-dependent protein kinase activity
39. Distinct dynamin-dependent and -independent mechanisms target structurally homologous dopamine receptors to different endocytic membranes
40. 2 dopamine receptors
41. cAMP-dependent protein kinase and protein kinase C consensus site mutations of the beta-adrenergic receptor. Effect on desensitization and stimulation of adenylylcyclase
42. 1 dopamine receptor
43. 1 dopamine receptor: Evidence for involvement of both cyclic AMP-dependent and receptor-specific protein kinases