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Volumn 10, Issue 4, 2004, Pages 525-530

Expression of HIF-2α/EPAS1 in hepatocellular carcinoma

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 2ALPHA; PARAFFIN; VASCULOTROPIN; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; HYPOXIA INDUCIBLE FACTOR 2, ALPHA SUBUNIT; HYPOXIA-INDUCIBLE FACTOR 2, ALPHA SUBUNIT; TRANSACTIVATOR PROTEIN; VASCULOTROPIN A;

EID: 1542314896     PISSN: 10079327     EISSN: None     Source Type: Journal    
DOI: 10.3748/wjg.v10.i4.525     Document Type: Article
Times cited : (38)

References (46)
  • 2
    • 0034682513 scopus 로고    scopus 로고
    • The transcription factor EPAS1/hypoxia -inducible factor2 alpha plays an important role in vascular remodeling
    • Peng J, Zhang L, Drysdale L, Fong GH. The transcription factor EPAS1/hypoxia -inducible factor2 alpha plays an important role in vascular remodeling. Proct Natl Acad Sci U S A 2000; 97: 8386-8391
    • (2000) Proct. Natl. Acad. Sci. U S A , vol.97 , pp. 8386-8391
    • Peng, J.1    Zhang, L.2    Drysdale, L.3    Fong, G.H.4
  • 3
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian H, Mcknight SL, Russell DW. Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev 1997; 11: 72-82
    • (1997) Genes Dev. , vol.11 , pp. 72-82
    • Tian, H.1    Mcknight, S.L.2    Russell, D.W.3
  • 4
    • 0034663989 scopus 로고    scopus 로고
    • HIF-1 and human disease: One highly involved factor
    • Semenza GL. HIF-1 and human disease: one highly involved factor. Genes Dev 2000; 14: 1983-1991
    • (2000) Genes Dev. , vol.14 , pp. 1983-1991
    • Semenza, G.L.1
  • 5
    • 0027732162 scopus 로고
    • Antineoplastic drug resistance and breast cancer
    • Morrow CS, Cowan KH. Antineoplastic drug resistance and breast cancer. Ann NY Acad Sci 1993; 698: 289-312
    • (1993) Ann. NY Acad. Sci. , vol.698 , pp. 289-312
    • Morrow, C.S.1    Cowan, K.H.2
  • 7
    • 0031971047 scopus 로고    scopus 로고
    • Expression of ARNT, ARNT2, HIF1 α, HIF2α and Ah receptor mRNAs in the developing mouse
    • Jain S, Maltepe E, Lu MM, Simon C, Bradfield CA. Expression of ARNT, ARNT2, HIF1 α, HIF2α and Ah receptor mRNAs in the developing mouse. Mech Dev 1998; 73: 117-123
    • (1998) Mech. Dev. , vol.73 , pp. 117-123
    • Jain, S.1    Maltepe, E.2    Lu, M.M.3    Simon, C.4    Bradfield, C.A.5
  • 8
    • 0031000736 scopus 로고    scopus 로고
    • A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development
    • Ema M, Taya S, Yokotani N, Sogawa K, Matsuda Y, Fujii-Kuriyama Y. A novel bHLH-PAS factor with close sequence similarity to hypoxia-inducible factor 1α regulates the VEGF expression and is potentially involved in lung and vascular development. Proct Natl Acad Sci U S A 1997; 94: 4273-4278
    • (1997) Proct. Natl. Acad. Sci. U S A , vol.94 , pp. 4273-4278
    • Ema, M.1    Taya, S.2    Yokotani, N.3    Sogawa, K.4    Matsuda, Y.5    Fujii-Kuriyama, Y.6
  • 9
    • 0343683375 scopus 로고    scopus 로고
    • HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels
    • Flamme I, Frohlich T, von Reutern M, Kappel A, Damert A, Risau W. HRF, a putative basic helix-loop-helix-PAS-domain transcription factor is closely related to hypoxia-inducible factor-1 alpha and developmentally expressed in blood vessels. Mech Dev 1997; 63: 51-60
    • (1997) Mech. Dev. , vol.63 , pp. 51-60
    • Flamme, I.1    Frohlich, T.2    von Reutern, M.3    Kappel, A.4    Damert, A.5    Risau, W.6
  • 10
    • 0031870653 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2 alpha
    • Flamme I, Krieg M, Plate KH. Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2 alpha. Am J Pathol 1998; 153: 25-29
    • (1998) Am. J. Pathol. , vol.153 , pp. 25-29
    • Flamme, I.1    Krieg, M.2    Plate, K.H.3
  • 11
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in normal human tissues, cancers, and tumor-associated macrophages
    • Talks KL, Turley H, Gatter KC, Maxwell PH, Pugh CW, Ratcliffe PJ, Harris AL. The expression and distribution of the hypoxia-inducible factors HIF-1 alpha and HIF-2 alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol 2000; 157: 411-421
    • (2000) Am. J. Pathol. , vol.157 , pp. 411-421
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6    Harris, A.L.7
  • 12
    • 0030242225 scopus 로고    scopus 로고
    • Fighting cancer by attacking its blood supply
    • Folkman J. Fighting cancer by attacking its blood supply. Sci Am 1996; 275: 150-154
    • (1996) Sci. Am. , vol.275 , pp. 150-154
    • Folkman, J.1
  • 13
    • 0036792605 scopus 로고    scopus 로고
    • Angiogenesis and vascular architecture in pheochromocytomas: Distinctive traits in malignant tumors
    • Favier J, Plouin PF, Corvol P, Gasc JM. Angiogenesis and vascular architecture in pheochromocytomas: distinctive traits in malignant tumors. Am J Pathol 2002; 161: 1235-1246
    • (2002) Am. J. Pathol. , vol.161 , pp. 1235-1246
    • Favier, J.1    Plouin, P.F.2    Corvol, P.3    Gasc, J.M.4
  • 14
    • 0642275613 scopus 로고    scopus 로고
    • aHIF but not HIF-1alpha transcription a poor prognostic marker in human breast cancer. INSERMU484, Clermont-Ferrand, French
    • Cayre A, Rossignal F, Clottes E, Penault LF. aHIF but not HIF-1alpha transcription a poor prognostic marker in human breast cancer. INSERMU484, Clermont-Ferrand, French. Breast Cancer Res 2003; 5: 223-230
    • (2003) Breast Cancer Res. , vol.5 , pp. 223-230
    • Cayre, A.1    Rossignal, F.2    Clottes, E.3    Penault, L.F.4
  • 15
    • 0017645626 scopus 로고
    • Hypoxia in neoplastic tissue
    • Vaupel P. Hypoxia in neoplastic tissue. Microvasc Res 1977; 13: 399-408
    • (1977) Microvasc. Res. , vol.13 , pp. 399-408
    • Vaupel, P.1
  • 16
    • 0014514055 scopus 로고
    • Quantitative techniques for study of the anatomy and function of small blood vessels in tumors
    • Tannock IF, Steel GG. Quantitative techniques for study of the anatomy and function of small blood vessels in tumors. J Natl Cancer Inst 1969; 42: 771-782
    • (1969) J. Natl. Cancer Inst. , vol.42 , pp. 771-782
    • Tannock, I.F.1    Steel, G.G.2
  • 17
    • 0015261969 scopus 로고
    • The proliferation of capillary endothelial cells
    • Tannock IF, Hayashi S. The proliferation of capillary endothelial cells. Cancer Res 1972; 32: 77-82
    • (1972) Cancer Res. , vol.32 , pp. 77-82
    • Tannock, I.F.1    Hayashi, S.2
  • 18
    • 0024408986 scopus 로고
    • Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: A review
    • Vaupel P, Kallinowski F, Okunieff P. Blood flow, oxygen and nutrient supply, and metabolic microenvironment of human tumors: a review. Cancer Res 1989; 49: 6449-6465
    • (1989) Cancer Res. , vol.49 , pp. 6449-6465
    • Vaupel, P.1    Kallinowski, F.2    Okunieff, P.3
  • 19
    • 0033302303 scopus 로고    scopus 로고
    • Transport of molecules, particles, and cells in solid tumors
    • Jain RK. Transport of molecules, particles, and cells in solid tumors. Annu Rev Biomed Eng 1999; 1: 241-263
    • (1999) Annu. Rev. Biomed. Eng. , vol.1 , pp. 241-263
    • Jain, R.K.1
  • 20
    • 0026604943 scopus 로고
    • Blood flow in six human melanoma xenograft lines with different growth characteristics
    • Lyng H, Skretting A, Rofstad EK. Blood flow in six human melanoma xenograft lines with different growth characteristics. Cancer Res 1992; 52: 584-592
    • (1992) Cancer Res. , vol.52 , pp. 584-592
    • Lyng, H.1    Skretting, A.2    Rofstad, E.K.3
  • 21
    • 0023909330 scopus 로고
    • Determinants of tumor blood flow: A review
    • Jain RK. Determinants of tumor blood flow: a review. Cancer Res 1988; 48: 2641-2658
    • (1988) Cancer Res. , vol.48 , pp. 2641-2658
    • Jain, R.K.1
  • 22
    • 0031823016 scopus 로고    scopus 로고
    • The molecular basis of hypoxia response pathways: Tumour hypoxia as a therapy target
    • Blancher C, Harris AL. The molecular basis of hypoxia response pathways: tumour hypoxia as a therapy target. Cancer Metastasis Rev 1998; 17: 187-194
    • (1998) Cancer Metastasis Rev. , vol.17 , pp. 187-194
    • Blancher, C.1    Harris, A.L.2
  • 24
    • 0031839355 scopus 로고    scopus 로고
    • Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1
    • Harmey JH, Dimitriadis E, Kay E, Redmond HP, Bouchier-Hayes D. Regulation of macrophage production of vascular endothelial growth factor (VEGF) by hypoxia and transforming growth factor beta-1. Ann Surg Oncol 1998; 5: 271-278
    • (1998) Ann. Surg. Oncol. , vol.5 , pp. 271-278
    • Harmey, J.H.1    Dimitriadis, E.2    Kay, E.3    Redmond, H.P.4    Bouchier-Hayes, D.5
  • 25
    • 1842366022 scopus 로고    scopus 로고
    • Intracellular pool of vascular endothelial growth factor in human neutrophils
    • Gaudry M, Bregerie O, Andrieu V, El Benna. J, Pocidalo MA, Hakim J. Intracellular pool of vascular endothelial growth factor in human neutrophils. Blood 1997; 90: 4153-4161
    • (1997) Blood , vol.90 , pp. 4153-4161
    • Gaudry, M.1    Bregerie, O.2    Andrieu, V.3    El Benna, J.4    Pocidalo, M.A.5    Hakim, J.6
  • 28
  • 29
    • 0033067163 scopus 로고    scopus 로고
    • Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast
    • Leek RD, Landers RJ, Harris AL, Lewis CE. Necrosis correlates with high vascular density and focal macrophage infiltration in invasive carcinoma of the breast. Br J Cancer 1999; 79: 991-995
    • (1999) Br. J. Cancer , vol.79 , pp. 991-995
    • Leek, R.D.1    Landers, R.J.2    Harris, A.L.3    Lewis, C.E.4
  • 30
    • 0027960791 scopus 로고
    • Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression
    • Hlatky L, Tsionou C, Hahnfeldt P, Coleman CN. Mammary fibroblasts may influence breast tumor angiogenesis via hypoxia-induced vascular endothelial growth factor up-regulation and protein expression. Cancer Res 1994; 54: 6083-6086
    • (1994) Cancer Res. , vol.54 , pp. 6083-6086
    • Hlatky, L.1    Tsionou, C.2    Hahnfeldt, P.3    Coleman, C.N.4
  • 31
    • 0030944928 scopus 로고    scopus 로고
    • Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines
    • Negus RP, Stamp GW, Hadley J, Balkwill FR. Quantitative assessment of the leukocyte infiltrate in ovarian cancer and its relationship to the expression of C-C chemokines. Am J Pathol 1997; 150: 1723-1734
    • (1997) Am. J. Pathol. , vol.150 , pp. 1723-1734
    • Negus, R.P.1    Stamp, G.W.2    Hadley, J.3    Balkwill, F.R.4
  • 33
    • 0035860147 scopus 로고    scopus 로고
    • Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival
    • Giatromanolaki A, Koukourakis MI, Siviridis E, Turley H, Talks K, Pezzella F, Gatter KC, Harris AL. Relation of hypoxia inducible factor 1 alpha and 2 alpha in operable non-small cell lung cancer to angiogenic/molecular profile of tumors and survival. Br J Cancer 2001; 85: 881-890
    • (2001) Br. J. Cancer , vol.85 , pp. 881-890
    • Giatromanolaki, A.1    Koukourakis, M.I.2    Siviridis, E.3    Turley, H.4    Talks, K.5    Pezzella, F.6    Gatter, K.C.7    Harris, A.L.8
  • 34
    • 0021684729 scopus 로고
    • Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages
    • Polverini PJ, Leibovich SJ. Induction of neovascularization in vivo and endothelial proliferation in vitro by tumor-associated macrophages. Lab Invest 1984; 51: 635-642
    • (1984) Lab. Invest. , vol.51 , pp. 635-642
    • Polverini, P.J.1    Leibovich, S.J.2
  • 35
    • 0029867554 scopus 로고    scopus 로고
    • Migration of human monoctes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1
    • Barleon B, Sozzani S, Zhou D, Weich HA, Mantovani A, Marme D. Migration of human monoctes in response to vascular endothelial growth factor (VEGF) is mediated via the VEGF receptor flt-1. Blood 1996; 87: 3336-3343
    • (1996) Blood , vol.87 , pp. 3336-3343
    • Barleon, B.1    Sozzani, S.2    Zhou, D.3    Weich, H.A.4    Mantovani, A.5    Marme, D.6
  • 37
    • 0031876304 scopus 로고    scopus 로고
    • Production of vascular endothelial growth factor by murine macrophages: Regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway
    • Xiong M, Elson G, Legarda D, Leibovich SJ. Production of vascular endothelial growth factor by murine macrophages: regulation by hypoxia, lactate, and the inducible nitric oxide synthase pathway. Am J Pathol 1998; 153: 587-598
    • (1998) Am. J. Pathol. , vol.153 , pp. 587-598
    • Xiong, M.1    Elson, G.2    Legarda, D.3    Leibovich, S.J.4
  • 38
    • 0033780453 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas
    • Lewis JS, Landers RJ, Underwood JC, Harris AL, Lewis CE. Expression of vascular endothelial growth factor by macrophages is up-regulated in poorly vascularized areas of breast carcinomas. Pathol 2000; 192: 150-158
    • (2000) Pathol. , vol.192 , pp. 150-158
    • Lewis, J.S.1    Landers, R.J.2    Underwood, J.C.3    Harris, A.L.4    Lewis, C.E.5
  • 39
    • 0025697078 scopus 로고
    • Proteolytic balance and capillary morphogenesis
    • Pepper MS, Montesano R. Proteolytic balance and capillary morphogenesis. Cell Differ Dev 1990; 32: 319-327
    • (1990) Cell Differ. Dev. , vol.32 , pp. 319-327
    • Pepper, M.S.1    Montesano, R.2
  • 40
    • 0026483995 scopus 로고
    • Proteolytic balance and capillary morphogenesis in vitro
    • Pepper MS, Vassalli JD, Orci L, Montesano R. Proteolytic balance and capillary morphogenesis in vitro. EXS 1992; 61: 137-145
    • (1992) EXS , vol.61 , pp. 137-145
    • Pepper, M.S.1    Vassalli, J.D.2    Orci, L.3    Montesano, R.4
  • 41
    • 0032079312 scopus 로고    scopus 로고
    • Hypoxia stimulates urokinase receptor expression through a herne protein-dependent pathway
    • Graham CH, Fitzpatrick TE, McCrae KR. Hypoxia stimulates urokinase receptor expression through a herne protein-dependent pathway. Blood 1998; 91: 3300-3307
    • (1998) Blood , vol.91 , pp. 3300-3307
    • Graham, C.H.1    Fitzpatrick, T.E.2    McCrae, K.R.3
  • 42
    • 0033199018 scopus 로고    scopus 로고
    • Regulation of the urokinase-type plasminogen activator system by the von Hippel-Lindau tumor suppressor gene
    • Los M, Zaemari S, Foekens JA, Gebbink MF, Voest EE. Regulation of the urokinase-type plasminogen activator system by the von Hippel-Lindau tumor suppressor gene. Cancer Res 1999; 59: 4440-4445
    • (1999) Cancer Res. , vol.59 , pp. 4440-4445
    • Los, M.1    Zaemari, S.2    Foekens, J.A.3    Gebbink, M.F.4    Voest, E.E.5
  • 43
    • 0026592989 scopus 로고
    • Predictive factors for intrahepatic recurrence of hepatocellular carcinoma after partial hepatectomy
    • Arii S, Tanaka J, Yamazoe Y, Minematsu S, Morino T, Fujita K, Maetani S, Tobe T. Predictive factors for intrahepatic recurrence of hepatocellular carcinoma after partial hepatectomy. Cancer 1992; 69: 913-919
    • (1992) Cancer , vol.69 , pp. 913-919
    • Arii, S.1    Tanaka, J.2    Yamazoe, Y.3    Minematsu, S.4    Morino, T.5    Fujita, K.6    Maetani, S.7    Tobe, T.8
  • 44
    • 0025217055 scopus 로고
    • Clinicopathologic features and results of surgical treatment
    • Primary liver cancer in Japan. Liver Cancer Study Group of Japan
    • Primary liver cancer in Japan. Clinicopathologic features and results of surgical treatment. Liver Cancer Study Group of Japan. Ann Surg 1990; 211: 277-287
    • (1990) Ann. Surg. , vol.211 , pp. 277-287


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