A radical approach to treating inflammation

Trends in Pharmacological Sciences

Volumn 21, Issue 4, 2000, Pages 119-120

  Grisham, Matthew B ^a  

^a LOUISIANA STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIINFLAMMATORY AGENT; MANGANESEDICHLORO(3,10,13,20,26 PENTAAZATETRACYCLO[20.3.1.0(4,9).0(14,19)] 1(26),22(23),24 HEXACOSATRIENE); REACTIVE OXYGEN METABOLITE; SUPEROXIDE DISMUTASE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; CONTROLLED STUDY; EDEMA; INFLAMMATION; ISCHEMIA; NONHUMAN; PRIORITY JOURNAL; RAT; SHORT SURVEY;

ARTHRITIS, RHEUMATOID; FREE RADICAL SCAVENGERS; HUMANS; INFLAMMATION; INFLAMMATORY BOWEL DISEASES; NITRIC OXIDE; SUPEROXIDE DISMUTASE;

EID: 0034177606     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(99)01435-2     Document Type: Short Survey

References (9)

1. McCord J.M., Fridovich I. Superoxide dismutase. An enzymic function for erythrocuprein (hemocuprein). J. Biol. Chem. 244:1969;6049-6055.
2. Babior B.M.et al. Biological defense mechanisms. The production by leukocytes of superoxide, a potential bactericidal agent. J. Clin. Invest. 52:1973;741-744.
3. Curnutte J.T.et al. Defective superoxide production by granulocytes from patients with chronic granulomatous disease. New Engl. J. Med. 290:1974;593-597.
4. McCord J.M. Free radicals and inflammation: protection of synovial fluid by superoxide dismutase. Science. 185:1974;529-531.
5. Granger D.N.et al. Superoxide radicals in feline intestinal ischemia. Gastroenterology. 81:1981;22-29.
6. Salvemini D.et al. A nonpeptidyl mimic of superoxide dismutase with therapeutic activity in rats. Science. 286:1999;304-306.
7. Grisham M.B.et al. Nitric oxide. I. Physiological chemistry of nitric oxide and its metabolites: implications in inflammation. Am. J. Physiol. 276:1999;G315-G321.
8. Grisham M.B.et al. Modulation of leukocyte-endothelial interactions by reactive metabolites of oxygen and nitrogen: relevance to ischemic heart disease. Free Radic. Biol. Med. 25:1998;404-433.
9. Eiserich J.P.et al. Formation of nitric oxide-derived inflammatory oxidants by myeloperoxidase in neutrophils. Nature. 391:1998;393-397.