A second protein kinase CK1-mediated step negatively regulates Wnt signalling by disrupting the lymphocyte enhancer factor-1/β-catenin complex

Cellular and Molecular Life Sciences

Volumn 62, Issue 5, 2005, Pages 606-618

  Hammerlein A ^a,b   Weiske, J ^a   Huber, O ^a  

^a Institute of Clinical Chemistry and Pathobiochemistry   (Germany)

^b ABDA Bundesvereinigung Deutscher Apothekerverbande   (Germany)

Author keywords

catenin; CK1; CK2; LEF 1; Wnt signalling

Indexed keywords

AXIN; BETA CATENIN; CASEIN KINASE I; CASEIN KINASE II; DNA; GLYCOGEN SYNTHASE KINASE 3BETA; LYMPHOID ENHANCER FACTOR 1; WNT PROTEIN;

ARTICLE; CANCER PREVENTION; CANONICAL ANALYSIS; CARCINOGENESIS; CELL PROTECTION; COLON POLYPOSIS; COMPLEX FORMATION; CONTROLLED STUDY; DOWN REGULATION; EMBRYO; ENZYME ANALYSIS; GENE TARGETING; HUMAN; HUMAN CELL; PROTEIN DEGRADATION; PROTEIN DNA BINDING; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; REGULATORY MECHANISM; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION;

BETA CATENIN; BINDING SITES; CASEIN KINASE I; CASEIN KINASE II; CELL LINE, TUMOR; CYTOSKELETAL PROTEINS; DNA; DNA-BINDING PROTEINS; DOWN-REGULATION; GENES, REPORTER; HUMANS; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LUCIFERASES; LYMPHOID ENHANCER-BINDING FACTOR 1; PHOSPHORYLATION; PROTEIN INTERACTION MAPPING; PROTEIN STRUCTURE, TERTIARY; SERINE; SIGNAL TRANSDUCTION; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSCRIPTION, GENETIC; WNT PROTEINS;

EID: 15244338770     PISSN: 1420682X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00018-005-4507-7     Document Type: Article

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