Changes in adipocyte hormones leptin, resistin, and adiponectin in thyroid dysfunction

Journal of Cellular Biochemistry

Volumn 93, Issue 3, 2004, Pages 491-496

  Yaturu, Subhashini ^a,b   Prado, Susan ^b   Grimes, Sidney R ^b  

^a VETERANS AFFAIRS MEDICAL CENTER   (United States)

^b OVERTON BROOKS VA MEDICAL CENTER   (United States)

Author keywords

Adiponectin; Graves' disease; Hyperthyroidism; Hypothyroidism; Leptin; Resistin

Indexed keywords

ADIPONECTIN; LEPTIN; RESISTIN; HORMONE; RETN PROTEIN, HUMAN; SIGNAL PEPTIDE;

ADIPOCYTE; ARTICLE; CLINICAL ARTICLE; CONTROLLED STUDY; FOLLOW UP; GRAVES DISEASE; HORMONE BLOOD LEVEL; HUMAN; HYPERTHYROIDISM; PRIORITY JOURNAL; THYROID DISEASE; THYROID FUNCTION; BLOOD; METABOLISM; THYROID GLAND;

ADIPOCYTES; ADIPONECTIN; GRAVES DISEASE; HORMONES, ECTOPIC; HUMANS; HYPERTHYROIDISM; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; LEPTIN; RESISTIN; THYROID GLAND;

EID: 15044350554     PISSN: 07302312     EISSN: 10974644     Source Type: Journal    
DOI: 10.1002/jcb.20188     Document Type: Article

References (37)

1. Arita Y, Kihara S, Ouchi N, Takahashi M, Maeda K, Miyagawa J, Hotta K, Shimomura I, Nakamura T, Miyaoka K, Kuriyama H, Nishida M, Yamashita S, Okubo K, Matsubara K, Muraguchi M, Ohmoto Y, Funahashi T, Matsuzawa Y. 1999. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. Biochem Biophys Res Commun 257:79-83.
2. Berg AH, Combs TP, Scherer PE. 2002. ACRP30/adiponectin: An adipokine regulating glucose and lipid metabolism. Trends Endocrinol Metab 13:84-89.
3. Bruun JM, Lihn AS, Verdich C, Pedersen SB, Toubro S, Astrup A, Richelsen B. 2003. Regulation of adiponectin by adipose tissue-derived cytokines: In vivo and in vitro investigations in humans. Am J Physiol Endocrinol Metab 285:E527-E533.
4. Celik I, Akalin S, Erbas T. 1995. Serum levels of interleukin 6 and tumor necrosis factor-alpha in hyperthyroid patients before and after propylthiouracil treatment. Eur J Endocrinol 132:668-672.
5. Combs TP, Berg AH, Obici S, Scherer PE, Rossetti L. 2001. Endogenous glucose production is inhibited by the adipose-derived protein Acrp30. J Clin Invest 108:1875-1881.
6. Corbetta S, Englaro P, Giambona S, Persani L, Blum WF, Beck-Peccoz P. 1997. Lack of effects of circulating thyroid hormone levels on serum leptin concentrations. Eur J Endocrinol 137:659-663.
7. Duntas LH. 2002. Thyroid disease and lipids. Thyroid 12:287-293.
8. Hotamisligil GS, Shargill NS, Spiegelman BM. 1993. Adipose expression of tumor necrosis factor-alpha: Direct role in obesity-linked insulin resistance. Science 259:87-91.
9. Iglesias P, Alvarez Fidalgo P, Codoceo R, Diez JJ. 2003. Serum concentrations of adipocytokines in patients with hyperthyroidism and hypothyroidism before and after control of thyroid function. Clin Endocrinol (Oxf) 59:621-629.
10. Iossa S, Liverini G, Barletta A. 1992. Relationship between the resting metabolic rate and hepatic metabolism in rats: Effect of hyperthyroidism and fasting for 24 h. J Endocrinol 135:45-51.
11. Komorowski J, Jankiewicz J, Robak T, Blasinska-Morawiec M, Stepien H. 1998. Cytokines serum levels as the markers of thyroid activation in Graves' disease. Immunol Lett 60:143-148.
12. Korbonits M. 1998. Leptin and the thyroid-A puzzle with missing pieces. Clin Endocrinol (Oxf) 49:569-572.
13. Leonhardt U, Ritzel U, Schafer G, Decker W, Ramadori G. 1998. Serum leptin levels in hypo- and hyperthyroidism. J Endocrinol 157:75-79.
14. Liverini G, Iossa S, Barletta A. 1992. Relationship between resting metabolism and hepatic metabolism: Effect of hypothyroidism and 24 h fasting. Horm Res 38:154-159.
15. Mantzoros CS, Moschos S, Avramopoulos I, Kaklamani V, Liolios A, Doulgerakis DE, Griveas I, Katsilambros N, Flier JS. 1997. Leptin concentrations in relation to body mass index and the tumor necrosis factor-alpha system in humans. J Clin Endocrinol Metab 82:3408-3413.
16. McTernan CL, McTernan PG, Harte AL, Levick PL, Barnett AH, Kumar S. 2002a. Resistin, central obesity, and type 2 diabetes. Lancet 359:46-47.
17. McTernan PG, McTernan CL, Chetty R, Jenner K, Fisher FM, Lauer MN, Crocker J, Barnett AH, Kumar S. 2002b. Increased resistin gene and protein expression in human abdominal adipose tissue. J Clin Endocrinol Metab 87:2407.
18. Nogueiras R, Gualillo O, Caminos JE, Casanueva FF, Dieguez C. 2003. Regulation of resistin by gonadal, thyroid hormone, and nutritional status. Obes Res 11:408-414.
19. Ouchi N, Kihara S, Arita Y, Maeda K, Kuriyama H, Okamoto Y, Hotta K, Nishida M, Takahashi M, Nakamura T, Yamashita S, Funahashi T, Matsuzawa Y. 1999. Novel modulator for endothelial adhesion molecules: Adipocyte-derived plasma protein adiponectin. Circulation 100:2473-2476.
20. Pinkney JH, Goodrick SJ, Katz J, Johnson AB, Lightman SL, Coppack SW, Mohamed-Ali V. 1998. Leptin and the pituitary-thyroid axis: A comparative study in lean, obese, hypothyroid and hyperthyroid subjects. Clin Endocrinol (Oxf) 49:583-588.
21. Rajala MW, Obici S, Scherer PE, Rossetti L. 2003. Adipose-derived resistin and gut-derived resistin-like molecule-beta selectively impair insulin action on glucose production. J Clin Invest 111:225-230.
22. Salvi M, Pedrazzoni M, Girasole G, Giuliani N, Minelli R, Wall JR, Roti E. 2000. Serum concentrations of proinflammatory cytokines in Graves' disease: Effect of treatment, thyroid function, ophthalmopathy and cigarette smoking. Eur J Endocrinol 143:197-202.
23. Seven R. 2001. Thyroid status and leptin in Basedow-Graves and multinodular goiter patients. J Toxicol Environ Health A 63:575-581.
24. Smith SR, Bai F, Charbonneau C, Janderova L, Argyropoulos G. 2003. A promoter genotype and oxidative stress potentially link resistin to human insulin resistance. Diabetes 52:1611-1618.
25. Sreenan S, Caro JF, Refetoff S. 1997. Thyroid dysfunction is not associated with alterations in serum leptin levels. Thyroid 7:407-409.
26. Steppan CM, Lazar MA. 2002. Resistin and obesity-associated insulin resistance. Trends Endocrinol Metab 13:18-23.
27. Steppan CM, Bailey ST, Bhat S, Brown EJ, Banerjee RR, Wright CM, Patel HR, Ahima RS, Lazar MA. 2001. The hormone resistin links obesity to diabetes. Nature 409:307-312.
28. Valcavi R, Zini M, Peino R, Casanueva FF, Dieguez C. 1997. Influence of thyroid status on serum immunoreactive leptin levels. J Clin Endocrinol Metab 82:1632-1634.
29. Wahrenberg H, Wennlund A, Hoffstedt J. 2002. Increased adipose tissue secretion of interleukin-6, but not of leptin, plasminogen activator inhibitor-1 or tumour necrosis factor alpha, in Graves' hyperthyroidism. Eur J Endocrinol 146:607-611.
30. Walton KW, Scott PJ, Dykes PW, Davies JW. 1965. The significance of alterations in serum lipids in thyroid dysfunction. II. Alterations of the metabolism and turnover of 131-I-low-density lipoproteins in hypothyroidism and thyrotoxicosis. Clin Sci 29:217-238.
31. Weetman AP. 2000. Graves' disease. N Engl J Med 343:1236-1248.
32. Weyer C, Funahashi T, Tanaka S, Hotta K, Matsuzawa Y, Pratley RE, Tataranni PA. 2001. Hypoadiponectinemia in obesity and type 2 diabetes: Close association with insulin resistance and hyperinsulinemia. J Clin Endocrinol Metab 86:1930-1935.
33. Yamauchi T, Kamon J, Waki H, Terauchi Y, Kubota N, Hara K, Mori Y, Ide T, Murakami K, Tsuboyama-Kasaoka N, Ezaki O, Akanuma Y, Gavrilova O, Vinson C, Reitman ML, Kagechika H, Shudo K, Yoda M, Nakano Y, Tobe K, Nagai R, Kimura S, Tomita M, Froguel P, Kadowaki T. 2001. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity. Nat Med 7:941-946.
34. Yang WS, Lee WJ, Funahashi T, Tanaka S, Matsuzawa Y, Chao CL, Chen CL, Tai TY, Chuang LM. 2001. Weight reduction increases plasma levels of an adipose-derived anti-inflammatory protein, adiponectin. J Clin Endocrinol Metab 86:3815-3819.
35. Yoshida T, Monkawa T, Hayashi M, Saruta T. 1997. Regulation of expression of leptin mRNA and secretion of leptin by thyroid hormone in 3T3-L1 adipocytes. Biochem Biophys Res Commun 232:822-826.
36. Zhang Y, Proenca R, Maffei M, Barone M, Leopold L, Friedman JM. 1994. Positional cloning of the mouse obese gene and its human homologue. Nature 372:425-432.
37. Zimmermann-Belsing T, Dreyer M, Holst JJ, Feldt-Rasmussen U. 1998. The relationship between the serum leptin concentrations of thyrotoxic patients during treatment and their total fat mass is different from that of normal subjects. Clin Endocrinol (Oxf) 49:589-595.