Cisplatin-Induced Renal Interstitial Fibrosis in Neonatal Rats, Developing as Solitary Nephron Unit Lesions

Toxicologic Pathology

Volumn 33, Issue 2, 2005, Pages 207-217

  Yamate, Jyoji ^a   Machida, Yuuko ^a   Ide, Mika ^a   Kuwamura, Mitsuru ^a   Kotani, Takao ^a   Sawamoto, Osamu ^b   Lamarre, Jonathan ^c  

^a Osaka Prefecture University   (Japan)

^b OTSUKA PHARMACEUTICAL CO LTD   (Japan)

^c UNIVERSITY OF GUELPH   (Canada)

Author keywords

Cisplatin induced renal fibrosis; macrophages; neonatal rat; nephrogenesis; nephron unit lesion

Indexed keywords

CISPLATIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL DEATH; CONTROLLED STUDY; DIAGNOSTIC VALUE; DRUG INDUCED DISEASE; EPITHELIUM CELL; HISTOPATHOLOGY; KIDNEY FIBROSIS; MACROPHAGE; MYOFIBROBLAST; NEPHRON; NEWBORN; NEWBORN CARE; NICK END LABELING; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; RAT;

ACTINS; ANIMALS; ANIMALS, NEWBORN; ANTINEOPLASTIC AGENTS; APOPTOSIS; BIOLOGICAL MARKERS; BODY WEIGHT; CISPLATIN; DISEASE MODELS, ANIMAL; FIBROSIS; IN SITU NICK-END LABELING; MACROPHAGES; NEPHRITIS, INTERSTITIAL; NEPHRONS; RATS; RATS, INBRED F344; RNA, MESSENGER; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1;

EID: 15044344865     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1080/01926230490523978     Document Type: Article

References (62)

1. Akagi Y, Isaka Y, Arai M, Kaneko T, Takenaka M, Moriyama T, Kaneda Y, Ando A, Orita Y, Kamada T, Ueda N, Imai E Inhibition of TGF-β1 expression by antisense oligonucleotides suppressed extra-cellular matrix accumulation in experimental glomerulonephritis Kidney Int 1996 50 148-55
2. Alvarez RJ, Sun MJ, Haverty TP, Iozzo RV, Myers JC, Neilson EG Biosynthetic and proliferative characteristics of tubulointerstitial fibroblasts probed with paracrine cytokines Kidney Int 1992 41 14 23
3. Basile DP, Hammerman MR TGF-β in renal development and renal growth Miner Electrolyte Metab 1998 24 144-8
4. Border WA, Noble NA TGF-β in kidney fibrosis: a target for gene therapy Kidney Int 1997 51 1388-96
5. Cass DL, Meuli M, Adzick NS Scar wars: implications of fetal wound healing for the pediatric burn patient Pediatr Surg Int 1997 12 484-89
6. Cheng S, Lovett DH Gelatinase A (MMP-2) is necessary and sufficient for renal tubular cell epithelial-mesenchymal transformation Am J Pathol 2003 162 1937-49
7. Chevalier RL Growth factors and apoptosis in neonatal ureteral obstruction J Am Soc Nephrol 1996 7 1098 105
8. Chomczynski P A reagent for the single-step simultaneous isolation of RNA, DNA and proteins from cell and tissue samples Biotechniques 1993 15 532-37
9. Clark DA, Coker R Transforming growth factor-beta (TGF-β) Int J Biochem Cell Biol 1998 30 293-8
10. Coker RK, Laurent GJ, Shahzeidi S, Lympany PA, DuBois RM, Jeffery PK, McAnulty RJ Transforming growth factors-beta 1, -beta 2, and -beta 3 stimulate fibroblast procollagen production in vitro but are differentially expressed during bleomycin-induced lung fibrosis Am J Pathol 1997 150 981-91
11. Coles HS, Burne JF, Raff MC Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor Development 1993 118 777-84
12. Cook HT, Khan SB, Allen A, Bhangal G, Smith J, Lobb RR, Pusey CD Treatment with an antibody to VLA-1 integrin reduces glomerular and tubulointerstitial scarring in a rat model of crescent glomerulonephritis Am J Pathol 2002 161 1265-72
13. Creely JJ, DiMari SJ, Howe AM, Haralson MA Effects of transforming growth factor-β on collagen synthesis by normal rat kidney epithelial cells Am J Pathol 1992 140 45 55
14. Damoiseaux JG, Döpp EA, Calame W, Chao D, MacPherson GG, Dijkstra CD Rat macrophage lysosomal membrane antigen recognized by monoclonal antibody ED1 Immunology 1994 83 140-7
15. Desmouliere A, Redard M, Darby I, Gabbiani G Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar Am J Pathol 1995 146 56 66
16. Diamond JR, Pesek I, Ruggieri S, Karnovsky MJ Essential fatty acid deficiency during acute puromycin nephrosis ameliorates late renal injury Am J Physiol 1989 257 F798 807
17. Diamond JR, van Goor H, Ding G, Engelmyer E Myofibroblasts in experimental hydronephrosis Am J Pathol 1995 146 121-9
18. Dijkstra CD, Döpp EA, Joling P, Kraal G The heterogeneity of mononuclear phagocytes in lymphoid organs: distinct macrophage subpopulations in the rat recognized by monoclonal antibodies ED1, ED2 and ED3 Immunology 1985 54 589-99
19. Eddy AA Expression of genes that promote renal interstitial fibrosis in rats with proteinurea Kidney Int 1996 54 S49 54
20. Fields RC, Schoenecker JG, Hart JP, Hoffman MR, Pizzo SV, Lawson JH Protease-activated receptor-2 signaling triggers dendritic cell development Am J Pathol 2003 162 1817-22
21. Frazier KS, Paredes A, Dube P, Styer E Connective tissue growth factor expression in the rat remnant kidney model and association with tubular epithelial cells undergoing transdifferentiation Vet Pathol 2000 37 328-35
22. Friedman SL Molecular regulation of hepatic fibrosis, an integrated cellular response to tissue injury J Biol Chem 2000 275 2247-50
23. Geleilete TJ, Melo GC, Costa RS, Volpini RA, Soares TJ, Coimbra TM Role of myofibroblasts, macrophages, transforming growth factor-beta, endothelin, angiotensin-II, and fibronectin in the progression of tubulointerstitial nephritis induced by gentamicin J Nephrol 2002 15 633-42
24. Haralambous-Gasser A, Chan D, Walker RG, Powell HR, Becker GJ, Jones CL Collagen studies in newborn rat kidneys with incomplete ureteric obstruction Kidney Int 1993 44 593 605
25. Hellerbrand C, Stefanovic B, Giordano F, Burchardt ER, Brenner DA The role of TGF-beta 1 in initiating hepatic stellate cell activation in vivo J Hepatol 1999 30 77 87
26. Hines JE, Johnson SJ, Burt AD In vivo responses of macrophages and perisinusoidal cells to cholestatic liver injury Am J Pathol 1993 142 511-8
27. Ide M, Yamate J, Machida Y, Nakanishi M, Kuwamura M, Kotani T, Sawamoto O Emergence of different macrophage populations in hepatic fibrosis following thioacetoamide-induced acute hepatocyte injury in rats J Comp Pathol 2003 128 41 51
28. Johnson SJ, Hines JE, Burt AD Macrophage and perisinosoidal cell kinetics in acute liver injury J Pathol 1992 166 351-8
29. Jones CL, Buch S, Post M, McCulloch L, Liu E, Eddy AA Renal extracellular matrix accumulation in acute puromycin aminonucleoside nephrosis in rats Am J Pathol 1992 141 1381-96
30. Jones SG, Morrisey K, Williams JD, Phillips AO TGF-β1 stimulates the release of pre-formed bFGF from renal proximal tubular cells Kidney Int 1999 56 83 91
31. Jones TW, Chopra S, Kaufman JS, Flamenbaum W, Trump BF Cis-diamminedichloroplatinum(II)-induced acute renal failure in the rat: correlation of structural and functional alterations Lab Invest 1985 52 363-74
32. Kuncio GS, Neilson EG, Haverty T Mechanisms of tubuloin-terstitial fibrosis Kidney Int 1991 39 550-6
33. Lan HY, Mitsuhashi H, Ng YY, Nikolic-Paterson DJ, Yang N, Mu A, Atkins RC Macrophage apoptosis in rat crescentic glomerulonephritis Am J Pathol 1997 151 531-8
34. Lieberthal W, Triaca V, Levine J Mechanisms of death induced by cisplatin in proximal tubular epithelial cells: apoptosis vs. necrosis Am J Physiol 1996 270 F700 8
35. Liu A, Dardik A, Ballermann BJ Neutralizing TGF-β1 antibody infusion in neonatal rat delays in vivo glomerular capillary formation Kidney Int 1999 56 1334-48
36. Mackensen-Haen S, Bohle A, Christensen J, Wehrmann M, Kendziorra H, Kokot F The consequences for renal function of widening of the interstitium and changes in the tubular epithelium of the renal cortex and outer medulla in various renal disease Clin Nephrol 1992 37 70-7
37. Micera A, Vigneti E, Pickholtz D, Reich R, Pappo O, Bonini S, Maquart FX, Aloe L, Levi-Achaffer F Nerve growth factor displays stimulatory effects on human skin and lung fibroblasts, demonstrating a direct role for this factor in tissue repair Proc Natl Acad Sci USA 2001 98 6162-67
38. Minto AWM, Erwing LP, Rees AJ Heterogeneity of macrophage activation in anti-thy-1.1 nephritis Am J Pathol 2003 163 2033-41
39. Moriyama H, Yamamoto T, Takatsuka H, Umezu H, Tokunaga K, Nagano T, Arakawa M, Naito M Expression of macrophage colony-stimulating factor and its receptor in hepatic granulomas of Kupffer-cell-depleted mice Am J Pathol 1997 150 2047-60
40. Nagata M, Nakauchi H, Nakayama KI, Nakayama K, Loh D, Watanabe T Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice Am J Pathol 1996 148 1601-11
41. Nakatsuji S, Yamate J, Kuwamura M, Kotani T, Sakuma S In vivo responses of macrophages and myofibroblasts in the healing following isoproterenol-induced myocardial injury in rats Virchows Arch 1997 430 63-9
42. Ng YY, Huang TP, Yang WC, Chen ZP, Yang AH, Mu W, Nikolic-Paterson DJ, Atkins RC, Lan HY Tubular epithelial-myofibroblast transdifferentiation in progressive tubulointerstitial fibrosis in 5/6 nephrectomized rats Kidney Int 1998 54 864-76
43. Pontén A, Li X, Thorén P, Aase K, Sjöblom T, Ostman A, Eriksson U Transgenic overexpression of platelet-derived growth factor-c in the mouse heart induces cardiac fibrosis, hypertrophy, and dilated cardiomyopathy Am J Pathol 2003 163 673-82
44. Rescigno M, Winzler C, Delia D, Mutini C, Lutz M, Ricciardi-Castagnoli P Dendritic cell maturation is required for initiation of the immune response J Leukocyte Biol 1997 61 415-21
45. Suzuki K, Uetsuka K, Nakayama H, Doi K Kinetics of transforming growth factor-beta 1 and extracellular matrix in renal tubulointerstitial lesions of mercuric chloride-treated Brown Norway rats Int J Exp Pathol 1999 80 125-32
46. Takahashi K, Naito M, Takeya M Development and heterogeneity of macrophages and their related cells through their differentiation pathways Pathol Int 1996 46 473-85
47. Tamaki K, Okuda S, Ando T, Iwamoto T, Nakayama M, Fujishima M TGF-β1 in glomerulosclerosis and interstitial fibrosis of adriamycin nephropathy Kidney Int 1994 45 525-36
48. Tanuma N, Kojima T, Shin T, Aikawa Y, Kohji T, Ishihara Y, Matsumoto Y Competitive PCR quantification of pro- and anti-inflammatory cytokine mRNA in the central nervous system during autoimmune encephalomyelitis J Neuroimmunol 1997 73 197 206
49. Thompson KC, Trowern A, Fowell A, Marathe M, Haycock C, Arthur MJ, Sheron N Primary rat and mouse hepatic stellate cells express the macrophage inhibitor cytokine interleukin-10 during the course of activation in vitro Hepatology 1998 28 1518-24
50. Tsujino K, Yamate J, Tsukamoto Y, Kumagai D, Kannan Y, Jippo T, Kuwamura M, Kotani T, Takeya M, Sakuma S Establishment and characterization of cell lines derived from a transplantable rat malignant meningioma: morphological heterogeneity and production of nerve growth factor Acta Neuropathol 1997 93 461-70
51. Wright EJ, McCaffrey TA, Robertson AP, Vaughan ED Jr, Felsen D Chronic unilateral ureteral obstruction is associated with interstitial fibrosis and tubular expression of transforming growth factor-β Lab Invest 1996 74 528-37
52. Wu L, Xia YP, Roth SI, Gruskin E, Mustoe TA Transforming growth factor-beta 1 fails to stimulate wound healing and impairs its signal transduction in an aged ischemic ulcer model Am J Pathol 1999 154 301-9
53. Yamashiro S, Takeya M, Nishi T, Kuratsu J, Yoshimura T, Ushio Y, Takahashi K Tumor-derived monocyte chemoattractant protein-1 induces intratumoral infiltration of monocyte-derived macrophage subpopulation in transplanted rat tumors Am J Pathol 1994 145 856-67
54. Yamate J, Kuriyama T, Kawashima M, Nakanishi M, Ide M, Kuwamura M, Tsukamoto Y, Kotani T, Nakatsuji S Establishment and characterization of transplantable tumor line (KB) and cell lines (KB-P and KB-D8) from a rat thymus-derived dendritic cell sarcoma Virchows Arch 2002a 440 616-26
55. Yamate J, Maeda M, Benn S, Laithwaite JE, Allan A, Ide M, Kuwamura M, Kotani T, Sakuma S, LaMarre J Differential effects of transforming growth factor-β1, a fibrogenic factor, on macrophage-like cells (HS-P) and myofibroblastic cells (MT-9) in vivo Toxicol Pathol 2001 29 483-91
56. Yamate J, Okado A, Kuwamura M, Tsukamoto Y, Ohashi F, Kiso Y, Nakatsuji S, Kotani T, Sakuma S, LaMarre J Immunohistochemical analysis of macrophages, myofibroblasts, and transforming growth factor-β localization during rat renal interstitial fibrosis following long-term unilateral ureteral obstruction Toxicol Pathol 1998 26 793 801
57. Yamate J, Sato K, Ide M, Nakanishi M, Kuwamura M, Sakuma S, Nakatsuji S Participation of different macrophage populations and myofibroblastic cells in chronically developed renal interstitial fibrosis after cisplatin-induced renal injury in rats Vet Pathol 2002b 39 322-33
58. Yamate J, Sato K, Machida Y, Ide M, Sato S, Nakatsuji S, Kuwamura M, Kotani T, Sakuma S Cisplatin-induced rat renal interstitial fibrosis: a possible pathogenesis based on the data J Toxicol Pathol 2000a 13 237-47
59. Yamate J, Tatsumi M, Nakatsuji S, Kuwamura M, Kotani T, Sakuma S Immunohistochemical observations on the kinetics of macrophages and myofibroblasts in rat renal interstitial fibrosis induced by cis-diamminedichloroplatinum J Comp Pathol 1995 112 27 39
60. Yamate J, Yoshida H, Tsukamoto Y, Ide M, Kuwamura M, Ohashi F, Miyamoto T, Kotani T, Sakuma S, Takeya M Distribution of cells immunopositive for AM-3K, a novel monoclonal antibody recognizing human macrophages, in normal and diseased tissues of dogs, cats, horses, cattle, pigs, and rabbits Vet Pathol 2000b 37 168-76
61. Young BA, Burdmann EA, Johnson RJ, Alpers CE, Giachelli CM, Eng E, Andoh T, Bennett WM, Couser WG Cellular proliferation and macrophage influx precede interstitial fibrosis in cyclosporine nephrotoxicity Kidney Int 1995 48 439-48
62. Zhang J, Yu ZX, Fujita S, Yamaguchi ML, Ferrans VJ Interstitial dendritic cells of the rat heart: quantitative and ultrastructural changes in experimental myocardial infraction Circulation 1993 87 909 920