Apoptosis during an early stage of nephrogenesis induces renal hypoplasia in bcl-2-deficient mice

American Journal of Pathology

Volumn 148, Issue 5, 1996, Pages 1601-1611

  Nagata, Michio ^a   Nakauchi, Hiromitsu ^a   Nakayama, Kei Ichi ^b   Nakayama, Keiko ^b   Loh, Dennis ^b   Watanabe, Teruo ^a  

^a UNIVERSITY OF TSUKUBA   (Japan)

^b Nippon Roshe Research Center   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ONCOPROTEIN;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROLIFERATION; DEVELOPMENTAL GENETICS; EMBRYO; EMBRYO DEVELOPMENT; FETUS; GENOTYPE; KIDNEY CELL; KIDNEY DEVELOPMENT; KIDNEY HYPOPLASIA; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; BASE SEQUENCE; DNA; FEMALE; HETEROZYGOTE; KIDNEY; KIDNEY DISEASES; MALE; MICE; MICE, MUTANT STRAINS; MOLECULAR SEQUENCE DATA; NEPHRONS; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; STEM CELLS;

EID: 0029928192     PISSN: 00029440     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (30)

1. Saxen L Organogenesis of the Kidney Cambridge, Cambridge University Press, 1987, pp 13-87
2. Herzlinger D Renal stem cells and the lineage of the nephron Annu Rev Physiol 1994, 56 671-689
3. Ekblom P: Renal development. The Kidney. Physiology and Pathophysiology. Edited by W Seldin. New York, Raven Press, 1992, pp 475-487
4. Wada J, Liu ZZ, Alvares K, Kumar A, Wallner EI, Makino H, Kanwar YS: Cloning of cDNA for the a subunit of mouse insulin-like growth factor I receptor and the role of the receptor in metanephric development. Proc Natl Acad Sci USA 1993, 90:10360-10364
5. Liu ZZ, Kumar A, Wallner EI, Carone FA, Kanwar YS Trophic effect of insulin-like growth factor-I on metanephric development: relationship to proteoglycan. Eur J Cell Biol 1994, 65:378-391
6. Hammerman MR, Rogers SA, Ryan G: Growth factors and metanephrogenesis Am J Physiol 1993, 262 F523-F532
7. Woolf AS, Kolastsi-Joannou M, Hardman P, Andermacher E, Moorby C, Fine LG, Jat PS, Noble MD, Gherardi E: Roles of hepatocyte growth factor/scatter factor and the met receptor in the early kidney development of the metanephros. J Cell Biol 1995, 128:171-184
8. Kerr JFR, Wyllie AH, Currie AR: Apoptosis: a basic biological phenomenon with wide-ranging implication in tissue kinetics. Br J Cancer 1972, 26.239-257
9. Coles HSR, Burne JF, Raff MC: Large-scale normal cell death in the developing rat kidney and its reduction by epidermal growth factor Development 1993, 118 777-784
10. Saunders JW: Death in embryonic systems. Science 1966, 154:604-612
11. Koseki C, Herzlinger D, Al-Awqati Q: Apoptosis in metanephric development J Cell Biol 1992, 119:1327-1333
12. Tsujimoto Y, Finger LR, Nowell PC, Croce CM: Cloning of the chromosome breakpoint of neoplastic B cells with the t(14;18) chromosome translocation. Science 1994, 226.1097-1099
13. Hengertner MO, Horvitz HR. C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2. Cell 1994, 76 665-676
14. Hockenbery D, Nunez G, Milliman C, Schreiber RD, Korsemeyer SJ: Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death. Nature (Lond) 1990, 348:334-336
15. Chandler D, El-Naggar AK, Brisbay S, Redline RW, McDonnell TJ: Apoptosis and expression of the bcl-2 proto-oncogene in the fetal and adult human kidney. Hum Pathol 1994, 25:794-796
16. Novae DV, Korsemeyer SJ. Bcl-2 protein expression during murine development Am J Pathol 1994, 145. 61-73
17. Lu QL, Poulson R, Wong L, Nanby AM: Bcl-2 expression in adult and embryonic non-hematopoietic tissues. J Pathol 1993, 169 431-437
18. LeBrun DP, Warnke RA, Cleary ML: Expression of bcl-2 in fetal tissues suggests a role in morphogenesis. Am J Pathol 1993, 142:743-753
19. Nakayama K, Nakayama K, Negishi I, Kuida K, Sawa H, Loh DY: Targeted disruption of bcl-2 αβ in mice. occurrence of gray hair, polycystic kidney disease, and lymphocytopenia. Proc Natl Acad Sci USA 1994, 91 3700-3704
20. Veis DJ, Sorenson CM, Shutter JR, Korsemeyer SJ: Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair Cell 1993, 75:229-240
21. Kamada S, Shimono A, Shinto Y, Tsujimura T, Takahashi T, Noda T, Kitamura Y, Kondoh H, Tsujimoto Y bcl-2 deficiency in mice leads to pleiotropic abnormalities accelerated lymphoid cell death in thymus and spleen, polycystic kidney, hair hypopigmentation, and distorted small intestine Cancer Res 1995, 55:354-359
22. Sorenson CM, Rogers SA, Korsemeyer SJ, Hammerman MR. Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice Am J Physiol 1995, 268:F37-F81
23. Avner E, Sweeney WE: Polypeptide growth factors in metanephric growth and segmental nephron differentiation Pediatr Nephrol 1990, 4:372-377
24. Nagata M, Yamaguchi Y, Ito K. Loss of mitotic activity and expression of vimentin in glomerular epithelial cells in developing human kidneys. Anat Embryol 1993, 187. 275-279
25. Gavrieli Y, Sherman Y, Ben-Sasson A: Identification of programmed cell death in situ via specific labeling of nuclear DNA fragmentation. J Cell Biol 1992, 119:493-501
26. Marcia B: Knockout mice: round two Science 1994, 265:26-28
27. Nakayama K, Nakayama K, Negishi I, Kuida K, Shinkai Y, Louie MC, Fields LE, Lucas PJ, Stewart V, Alt FW, Loh DY: Disappearance of the lymphoid system in bcl-2 homozygous mutant chimeric mice. Science 1993, 261:1584-1587
28. Herzlinger D, Koseki C, Mikawa T, Al-Awqati Q: Metanephric mesenchyme contains multipotent stem cells whose fate is restricted after induction. Development 1992, 114.565-572
29. Oltivai ZN, Millman CL, Korsemeyer SJ: Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death Cell 1994, 74:609-619
30. Krajewski S, Krajewska M, Shabaik A, Miyashita T, Wang HG, Reed JC: Immunohistochemical determination of in vivo distribution of BAX, a dominant inhibitor of bcl-2 Am J Pathol 1994, 145 1323-1336