Proteome changes in ovarian epithelial cells derived from women with BRCA1 mutations and family histories of cancer

Molecular and Cellular Proteomics

Volumn 4, Issue 2, 2005, Pages 156-168

  Smith Beckerman, Diana M ^a   Fung, Kit W ^a   Williams, Katherine E ^b,e   Auerspeg, Nelly ^c   Godwin, Andrew K ^d   Burlingame, Alma L ^b  

^a SAN FRANCISCO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

^d FOX CHASE CANCER CENTER   (United States)

^e APPLIED BIOSYSTEMS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA TUBULIN; BRCA1 PROTEIN; COFILIN; F ACTIN; HEAT SHOCK PROTEIN; LACTOYLGLUTATHIONE LYASE; SERINE; UBIQUITIN THIOLESTERASE;

AMINO ACID SEQUENCE; ARTICLE; BREAST CANCER; CANCER CELL CULTURE; CONTROLLED STUDY; EPITHELIUM CELL; FAMILY HISTORY; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC PREDISPOSITION; HUMAN; HUMAN CELL; ISOELECTRIC POINT; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; OVARY CARCINOMA; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN MODIFICATION; PROTEIN PHOSPHORYLATION; TUMOR SUPPRESSOR GENE; TWO DIMENSIONAL GEL ELECTROPHORESIS; WESTERN BLOTTING;

ACTIN DEPOLYMERIZING FACTORS; ACTINS; ALGORITHMS; AMINO ACID SEQUENCE; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; EPITHELIAL CELLS; FAMILY HEALTH; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; GENES, BRCA1; HUMANS; IMMUNOBLOTTING; ISOELECTRIC FOCUSING; LACTOYLGLUTATHIONE LYASE; MASS SPECTROMETRY; MICROFILAMENT PROTEINS; MOLECULAR SEQUENCE DATA; MUTATION; NEOPLASMS; OVARIAN NEOPLASMS; OVARY; PEPTIDES; PHOSPHORYLATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; SILVER STAINING; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TIME FACTORS; TRYPSIN; UBIQUITIN; UP-REGULATION;

STAPHYLOCOCCUS PHAGE 3A;

EID: 14944380107     PISSN: 15359476     EISSN: None     Source Type: Journal    
DOI: 10.1074/mcp.M400157-MCP200     Document Type: Article

References (45)

1. Lynch, H. T., Casey, M. J., Lynch, J., White, T. E., and Godwin, A. K. (1998) Genetics and ovarian carcinoma. Semin. Oncol. 25, 265-280
2. Auersperg, N., Wong, A. S., Choi, K. C., Kang, S. K., and Leong, P.C. (2001) Ovarian surface epithelium: biology, endocrinology, and pathology. Endocr. Rev. 22, 255-288
3. Berman, D. B., Wagner-Costalas, J., Schultz, D. C., Lynch, H. T., and Godwin, A. K. (1996) Two distinct origins of a common BRCA-1 mutation in breast-ovarian cancer families: a genetic study of 15 185delAG-mutation kindreds. Am. J. Genet. 58, 1166-1176
4. Auersperg, N., Maines-Bandiera, S., Booth, J. H., Lynch, H. T., Godwin A. K., and Hamilton, T. C. (1995) Expression of two mucin antigens in culture of human ovarian surface epithelium: influence of a family history of ovarian cancer. Am. J. Obstet. Gynecol. 173, 558-565
5. Dyck, H. G., Hamilton, T. C., Godwin A. K., Lynch, H. T., Maines-Bandiera, S., and Auersperg, N. (1996) Autonomy of the epithelial phenotype in human ovarian surface epithelium: changes with neoplastic progression and with a family history of ovarian cancer. Int. J. Cancer 69, 429-436
6. Wong, A. S., Maines-Bandiera, S. L., Rosen, B., Wheelock, M. J., Johnson, K. R., Leung, P. C., Roskelly, C. D., and Auersperg, N. (1999) Constitutive and conditional cadherin expression in cultured human ovarian surface epithelium: influence of family history of ovarian cancer. Int. J. Cancer 81, 180-188
7. Miki, Y., Swensen, J., Shattuck-Eidens, D., Futreal, P. A., Harshman, K., Tavtigian, S., Liu, Q., Cochran, C., Bennett, L. M., Ding, W., Bell, R., Rosenthal, J., Hussey, C., Tran, T., McClure, M., Frye, C., Hattier, T., Phelps, R., Haugen-Strano, A., Katcher, H., Yakumo, K., Gholami, Z., Shaffer, D., Stone, S., Bayer, S., Wray, C., Bogden, R., Dayananth, P., Ward, J., Tonin, P., Narod, S., Bristow, P. K., Norris, F. H., Helvering, L., Morrison, P., Rosteck, P., Lai, M., Barrett, J. C., Lewis, C., Neuhausen, S., Cannon-Albright, L., Goldgar, D., Wiseman, R., Kamb, A., and Skolnick, M. H. (1994) A strong candidate for the breast and ovarian cancer susceptibility gene BRCA1. Science 286, 66-71
8. Easton, D. F., Ford, D., and Bishop, D. (1995) Breast and ovarian cancer incidence in BRCA1 mutation carriers. Breast Cancer Linkage Consortium. Am. J. Genet. 56, 265-271
9. Scully, R., and Livingston, D. M. (2000) In search of the tumor-suppressor functions of BRCA1 and BRCA2. Nature 408, 429-432
10. Venkitaraman, A. R. (2002) Cancer susceptibility and the functions of BRCA1 and BRCA2. Cell 108, 171-182
11. Khanna, K. K., and Jackson, S. P. (2001) DNA double-strand breaks: signaling, repair and the cancer connection. Nat. Genet. 27, 247-254
12. Greenblatt, M. S., Chappuis, P. O., Bond, J. P., Hamel, N., and Foulkes, W. D. (2001) TP 53 mutations in breast cancer associated with BRCA1 or BRCA2 germ-line mutations: distinctive spectrum and structural distribution. Cancer Res. 61, 4092-4097
13. Serova, O., Montagna, M., Torchard, D., Narod, S. A., Tonin, P., Sylla, B., Lynch, H. T., Feunteun, J., and Lenoir, G. M. (1996) A high incidence of BRCA1 mutations in 20 breast-ovarian cancer families. Am. J. Hum. Genet. 58, 42-51
14. Maines-Bandiera, S. L., Kruk, P. A., and Auersperg, N. (1992) Simian virus 40-transformed human ovarian surface epithelial cells escape normal growth controls but retain morphogenetic responses to extracellular matrix. Am. J. Obstet. Gynecol. 167, 729-735
15. Smith, D. M., Tran, H. M., and Epstein, L. B. (1995) Two-dimensional electrophoresis for purification, sequencing and identification of cytokine-induced proteins in normal and malignant cells, in Cytokines, a Practical Approach (Balkwill, F. R., ed) pp. 111-128, IRL Press, Oxford
16. Matsui, N. M., Smith, D. M., Clauser, K. R., Fichmann, J., Andrews, L. E., Sullivan, C. M., Burlingame, A. L., and Epstein, L. B. (1997) Immobilized pH gradient two-dimensional gel electrophoresis and mass spectrometric identification of cytokine-regulated proteins in ME-180 cervical carcinoma cells. Electrophoresis 18, 409-417
17. Garrels, J. I. (1979) Two dimensional electrophoresis and computer analysis of proteins synthesized by clonal cell lines. J. Biochem. 254, 7961-7977
18. Görg, A., Obermaier, C., Boguth, G., Harder, A., Scheibe, B., Wildgruber, R., and Weiss, W. (2000) The current state of two-dimensional electrophoresis with immobilized pH gradients. Electrophoresis 21, 1037-1053
19. Rosenfeld, J., Capdevielle, J., Guillemot, J. C., and Ferrara, P. (1992) In-gel digestion of proteins for internal sequence analysis after one- or two-dimensional gel electrophoresis. Anal. Biochem. 203, 173--179
20. Causer, K. R., Hall, S. C., Smith, D. M., Webb, J. W., Andrews, L. E., Tran, H. M., Epstein, L. B., and Burlingame, A. L. (1995) Rapid mass spectrometric peptide sequencing and mass matching for characterization of human melanoma proteins isolated by two-dimensional PAGE. Proc. Natl. Acad. Sci. U. S. A. 92, 5072-51076
21. Clauser, K. R., Baker, P. R., and Burlingame, A. L. (1999) Role of accurate mass measurement (±10 ppm) in protein identification strategies employing MS or MS/MS and database searching. Anal. Chem. 71, 2871-2882
22. Moriyama, K., Iida, K., and Yahara, I. (1996) Phosphorylation of Ser-3 of cofilin regulates its essential function on actin. Genes Cells 1, 73-86
23. Yahara, I., Aizawa, H., Moriyama, K., Iida, K., Yonezawa, N., Nishida, E., Hatanaka, H., and Inagaki, F. (1996) A role of cofilin/destrin in reorganization of actin cytoskeleton in response to stresses and cell stimuli. Cell Struct. Funct. 21, 421-424
24. dos Remedios, C. G., Chhabra, D., Kekic, M., Dedova, I. V., Tsubakihara, M., Berry, D. A., and Nosworthy, N. J. (2003) Actin binding proteins: regulation of cytoskeletal microfilaments. Physiol. Rev. 83, 433-473
25. Boraldi, F., Bini, L., Liberatori, S., Armini, A., Pallini, V., Tiozzo, R., Pasquali-Ronchetti, I., and Quaglino, D. (2003) Proteome analysis of dermal fibroblasts cultured in vitro from human healthy subjects of different ages. Proteomics 6, 917-929
26. Sanchez, J. C., Schaller, D., Ravier, F., Golaz, O., Jaccoued, S., Belet, M., Wilkins, M. R., James, R., Deshusses, J., and Hochstrasser, D. (1997) Translationally controlled tumor protein: a protein identified in several nontumoral cells including erythrocytes. Electrophoresis 18, 150-155
27. Gachet, Y., Toumier, S., Lee, M., Lazaris-Karatzas, A., Poulton, T., and Bommer, U. A. (1999) The growth-related, translationally controlled protein P23 has properties of a tubulin binding protein and associates transiently with microtubules during the cell cycle. J. Cell Sci. 112, 1257-1271
28. Chung, S., Kim, M., Choi, W., Chung, J., and Lee, K. (2002) Expression of translationally controlled tumor protein mRNA in human colon cancer. Cancer Lett. 156, 185-190
29. Bernstein, W. B., Painter, W. B., Chen, H., Minamide L. S., Abe, H., and Bamburg, J. R. (2000) Intracellular pH modulation of ADF/cofilin proteins. Cell Motil. Cytoskelet. 47, 319-336
30. Martoglio, A. M., Tom, B. D., Starkey, M., Corps, A. N., Charnock-Jones, D. S., and Smith, S. K. (2000) Changes in tumorigenesis- and angiogenesis-related gene transcript abundance profiles in ovarian cancer detected by tailor high density cDNA arrays. Mol. Med. 6, 750-765
31. Stierum, R., Gaspari, M., Dommels, Y., Ouatas, T., Pluk, H., Jespersen, S., Vogels, J., Verhoeckx, K., Groten, J., and van Ommen, B. (2003) Proteome analysis reveals novel proteins associated with proliferation and differentiation of the colorectal cancer cell line Caco-2. Biochim. Biophys. Acta 1650, 73-91
32. Fan, S., Wang, J., Yuan, R., Ma, Y., Meng, Q., Erdos, M. R., Pestell, R. G., Yuan, F., Auborn, K. J., Goldberg, I. D., and Rosen, E. M. (1999) BRAC1 inhibition of estrogen receptor signaling in transfected cells. Science 284, 1354-1356
33. Sarto, C., Valsecchi, C., Magni, F., Tremolada, L., Arizzi, C., Cordani, N., Casellato, S., Doro, G., Favini, P., Perego, R. A., Raimondo, F., Ferrero, S., Mocarelli, P., and Galli-Kienle, M. (2004) Expression of heat shock protein 27 in human renal cell carcinoma. Proteomics 4, 2252-2260
34. Xian Ma, Y., Fan, S., Xiong, J., Yuan, R. Q., Meng, Q., Gao, M., Goldberg, I. D., Fuqua, S. A., Pestell, R. G., and Rosen, E. M. (2003) Role of BRCA1 in heat shock response. Oncogene 22, 10-27
35. Arts, H. J., Hollema, H., Lemstra, W., Willemse, P. H., De Vries, E. G., Kampinga, H. H., and Van der Zee, A. G. (1999) Heat-shock-protein-27 (hsp 27) expression in ovarian carcinoma: relation in response to chemotherapy and prognosis. Int. J. Cancer 84, 234-238
36. Schneider, J., Jimenez, E., Narenbach, K., Marx, D., and Meden, H. (1998) Co-expression of the MDR1 gene and HSP27 in human ovarian cancer. Anticancer Res. 18, 2967-2971
37. Geisler, J. P., Geisler, H. E., Tammela, J., Wiemann, M. C., Zhou, Z., Miller, G. A., and Crabtree, W. (1998) Heat shock protein 27: an independent prognostic indicator of survival in patients with epithelial ovarian carcinoma. Gynecol. Oncol. 69, 14-16
38. Geisler, J. P., Tammela, J. E., Manahan, K. J., Geisler, H. E., Miller, G. A., Zhou, Z., and Wiemann, M. C. (2004) HSP27 in patients with ovarian carcinoma: still an independent prognostic indicator at 60 months follow-up. Eur. J. Gynaecol. Oncol. 25, 165-168
39. Hashizume, R., Fukuda, M., Maeda, I., Nishikawa, H., Oyake, D., Yabuki, Y., Ogata, H., and Ohta, T. (2001) The ring heterodimerbrca1-bard1 is a ubiquitin ligase inactivated by a breast cancer-derived mutation. J. Biol. Chem. 276, 14537-14540
40. Weekes, J., Morrison, K., Mullen, A., Wait, R., Barton, P., and Dunn, M. J. (2003) Hyperubiquitination of proteins in dilated cardiomyopathy. Proteomics 3, 208-216
41. Nishikawa, K., Li, H., Kawamura, R., Osaka, H., Wang, Y. L., Hara, Y., Hirokawa, T., Manago, Y., Amano, T., Noda, M., Aoki, S., and Wada, K. (2003) Alterations of structure and hydrolase activity of parkinsonism-associated human ubiquitin carboxyl-terminal hydrolase L1 variants. Proteomics 3, 714-723
42. Yu, W. R., and Olsson, Y. (1998) Accumulation of immunoreactivity to ubiquitin carboxyl-terminal hydrolase PGP 9.5 in axons of human cases with spinal cord lesions. Int. J. Neurosci. 95, 33-42
43. Jones, M. B., Krutzsch, H., Shu, H., Zhao, Y., Liotta, L. A., Kohn, E. C., and Petricoin, E. F., III (2002) Proteomic analysis and identification of new biomarkers and therapeutic targets for invasive ovarian cancer. Proteomics 2, 76-84
44. Petricoin, E. F., III, Ardekani, A. M., Hitt, B. A., Levine, P. J., Fusaro, V. A., Steinberg, S. M., Mills, G. B., Simone, C., Fishman, D. A., Kohn, E. C., and Liotta, L. A. (2002) Use of proteomic patterns in serum to identify ovarian cancer. Lancet 359, 572-577
45. Rui, Z., Jian-Guo, J., Yuan-Peng, T., Hai, P., and Bing-Gen, R. (2003) Use of serological proteomic methods to find biomarkers associated with breast cancer. Proteomics 4, 433-439