H1 receptor-mediated vasodilatation contributes to postexercise hypotension

Journal of Physiology

Volumn 563, Issue 2, 2005, Pages 633-642

  Lockwood, Jennifer M ^a   Wilkins, Brad W ^a   Halliwill, John R ^a  

^a UNIVERSITY OF OREGON   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FEXOFENADINE; HISTAMINE H1 RECEPTOR; HISTAMINE; HISTAMINE H1 RECEPTOR ANTAGONIST; DRUG DERIVATIVE; TERFENADINE;

ADULT; ARTERIAL PRESSURE; ARTICLE; AUSCULTATION; AUTOMATION; CALCULATION; CONDUCTANCE; CONTROLLED STUDY; CYCLING; DOPPLER ECHOGRAPHY; DRUG HALF LIFE; DRUG MECHANISM; EXERCISE; FEMALE; FEMORAL ARTERY FLOW; HUMAN; HUMAN EXPERIMENT; HYPOTENSION; MALE; MEAN ARTERIAL PRESSURE; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; RANDOMIZATION; SUPINE POSITION; VASODILATATION; AEROBIC EXERCISE; CLINICAL ARTICLE; DOPPLER FLOWMETRY; DRUG CLEARANCE; FEMORAL VASCULAR CONDUCTANCE; H1 RECEPTOR MEDIATED VASODILATATION; HEART OUTPUT; HISTAMINE RELEASE; LEG BLOOD FLOW; POST EXERCISE HYPOTENSION; SKIN BLOOD FLOW; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; DRUG EFFECT; PATHOPHYSIOLOGY; PHYSIOLOGY; RANDOMIZED CONTROLLED TRIAL;

ADULT; EXERCISE; FEMALE; HISTAMINE H1 ANTAGONISTS; HUMANS; HYPOTENSION; MALE; RECEPTORS, HISTAMINE H1; TERFENADINE; VASODILATION;

EID: 14944366816     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2004.080325     Document Type: Article

References (44)

1. Atkinson TP, White MV & Kaliner MA (1992). Histamine and serotonin. In Inflammation: Basic Principles and Clinical Correlates 2nd edn, ed. Gallin JI, Goldstein IM & Snyderman R, pp. 193-209. Raven Press, New York.
2. Baecke JAH, Burema J & Frijters JER (1982). A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 36, 936-942.
3. Beck L (1965). Histamine as the potential mediator of active reflex vasodilatation. Fed Proc 24, 1298-1310.
4. Borg G (1970). Perceived exertion as an indicator of somatic stress. Scand J Rehab Med 2-3, 92-98.
5. Brody MJ (1966). Neurohumoral mediation of active reflex vasodilatation. Fed Proc 25, 1583-1592.
6. Brown NJ & Roberts LJ (2001). Histimine, bradykinin, and their antagonists. In Goodman and Gilman's the Pharmacological Basis of Therapeutics. 10th edn, ed. Hardman JG & Limbird LE, pp. 645-667. McGraw-Hill, New York.
7. Campos HA, Montenegro M, Velasco M, Romero EA, Lvarez R & Urbina A (1999). Treadmill exercise-induced stress causes a rise of blood histamine in normotensive but not primary hypertensive humans. Eur J Pharmacol 383, 69-73.
8. Dill DB & Costill DL (1974). Calculation of percentage changes in volumes of blood, plasma, and red cells in dehydration. J Appl Physiol 37, 247-248.
9. Duda D, Lorenz W, Dick W, Celik I, Black A, Healy MJR & Black JW (1998). Can clinically relevant histamine release be accurately diagnosed in anaesthetised patients without plasma histamine measurements? Randomised study with nested sampling aimed to change paradigms. Inflammation Res 47, S73-S74.
10. Duner H & Pernow B (1958). Histamine and leukocytes in blood during muscular work in man. Scand J Clin Lab Invest 10, 394-396.
11. Floras JS, Sinkey CA, Aylward PE, Seals DR & Thoren PN (1989). Postexercise hypotension and sympathoinhibition in borderline hypertension. Hypertension 14, 28-35.
12. Gan K, Nishi I, Chin I & Slutsky AS (1993). On-line determination of pulmonary blood flow using respriatory inert gas analysis. IEEE Trans Biomed Eng 40, 1250-1259.
13. Halliwill JR (2001). Mechanisms and clinical implications of post-exercise hypotension in humans. Exerc Sport Sci Rev 29, 65-70.
14. Halliwill JR, Dinenno FA & Dietz NM (2003). Alpha-adrenergic vascular responsiveness during postexercise hypotension in humans. J Physiol 550, 279-286.
15. Halliwill JR, Minson CT & Joyner MJ (2000). Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans. J Appl Physiol 89, 1830-1836.
16. Halliwill JR, Taylor JA & Eckberg DL (1996a). Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 495, 279-288.
17. Halliwill JR, Taylor JA, Hartwig TD & Eckberg DL (1996b . Augmented baroreflex heart rate gain after moderate-intensity, dynamic exercise. Am J Physiol Regul Integr Comp Physiol 270, R420-R426.
18. Harries MG, Burge PS, O'Brien I, Cromwell O & Pepys J (1979). Blood histamine levels after exercise testing. Clin Allergy 9 437-441.
19. Hartley JPR, Charles TJ, Monie RD, Seaton A, Taylor WH, Westwood A & Williams JD (1981). Arterial plasma histamine after exercise in normal individuals and in patients with exercise-induced asthma. Clin Sci 61, 151-157.
20. Hill SJ (1990). Distribution, properties, and functional characteristics of three classes of histamine receptor. Pharmacol Rev 42, 45-82.
21. Johnson BD, Beck KC, Proctor DN, Miller J, Dietz NM & Joyner MJ (2000). Cardiac output during exercise by the open circuit acetylene washin method: comparsion with direct Fick. J Appl Physiol 88 1650-1658.
22. Kellogg DL, Crandall CG, Lui YC, Harkoudian N & Johnson JM (1998). Nitric oxide and cutaneous active vasodilation during heat stress in humans. J Appl Physiol 85, 824-892.
23. Kenney MJ & Seals DR (1993). Postexercise hypotension. Key features, mechanisms, and clinical significance. Hypertension 22 653-664.
24. Kohl HW, Blair SN, Paffenbarger RS, Macera CA & Kronenfeld JJ (1988). A mail survey of physical activity habits as related to measured physical fitness. Am J Epidemiol 127, 1228-1239.
25. Kulics JM, Collins HL & DiCarlo SE (1999). Postexercise hypotension is mediated by reductions in sympathetic nerve activity. Am J Physiol Heart Circ Physiol 276, H27-H32.
26. Lockwood JM, Pricher MP, Wilkins BW, Holowatz LA & Halliwill JR (2005). Postexercise hypotension is not explained by a prostaglandin-dependent peripheral vasodilation. J Appl Physiol 98, 447-453.
27. MacDonald JR (2002). Potential causes, mechanisms, and implications of post exercise hypotension. J Hum Hypertens 16 225-236.
28. Miki K, Yoshimoto M & Tanimizu M (2003). Acute shifts of baroreflex control of renal sympathetic nerve activity induced by treadmill exercise in rats. J Physiol 548, 313-322.
29. 3 receptors. Arch Pharmacol 346, 46-50.
30. Morgan DJR, Moodley I, Phillips MJ & Davies RJ (1983). Plasma histamine in asthmatic and control subjects following exercise: influence of circulating basophils and different assay techniques. Thorax 38, 771-777.
31. Morganroth ML, Young EW & Sparks HV (1977). Prostaglandin and histaminergic mediation of prolonged vasodilation after exercise. Am J Physiol Heart Circ Physiol 233, H27-H33.
32. Patil RD, DiCarlo SE & Collins HL (1993). Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine. Am J Physiol Heart Circ Physiol 265, H1184-H1188.
33. 2 histamine receptors in physiological vasodilator responses. Am J Physiol 231, 1002-1009.
34. Pricher MP, Holowatz LA, Williams JT, Lockwood JM & Halliwill JR (2004). Regional hemodynamics during postexercise hypotension I. Spanchnic and renal circulations. J Appl Physiol 97, 2065-2070.
35. Rao SP, Collins HL & DiCarlo SE (2002). Postexercise alpha-adrenergic receptor hyporesponsiveness in hypertensive rats is due to nitric oxide. Am J Physiol Regul Integr Comp Physiol 282, R960-R968.
36. Rengo F, Trimarco B & Chiariello M (1978). Relation between cholinergic and histaminergic components in reflex vasodilatation in the dog. Am J Physiol Heart Circ Physiol 234, H305-H311.
37. Russell T, Stoltz M & Weir S (1998). Pharmacokinetics, pharmacodynamics, and tolerance of single- and multiple-dose fexofendine hydrochloride in healthy male volunteers. Clin Pharmacol Ther 64 612-621.
38. Schrage WG, Joyner MJ & Dinenno FA (2004). Local inhibition of nitric oxide and prostaglandins independently reduce forearm exercise hyperaemia in humans. J Physiol 557, 599-611.
39. Senitko AN, Charkoudian N & Halliwill JR (2002). Influence of endurance exercise training status and gender on postexercise hypotension. J Appl Physiol 92, 2368-2374.
40. 2O exchange. J Appl Physiol 38, 913-918.
41. 1-receptor occupancy using 11C-Doxepin positron emisssion tomography. J Clin Pharm 44, 890-900.
42. Wilkins BW, Minson CT & Halliwill JR (2004). Regional hemodynamics during postexercise hypotension II. Cutaneous circulation. J Appl Physiol 97, 2071-2076.
43. Wong BJ, Wilkins BW & Minson CT (2004). H1 but not H2 histamine receptor activation contributes to the rise in skin blood flow during whole body heating in humans. J Physiol. 560, 941-948.
44. Yeh MP, Gardner RM, Adams TD & Yanowitz FG (1982). Computerized determination of pneumotachometer characteristics using a calibrated syringe. J Appl Physiol 53, 280-285.