α-Adrenergic vascular responsiveness during postexercise hypotension in humans

Journal of Physiology

Volumn 550, Issue 1, 2003, Pages 279-286

  Halliwill, John R ^a   Dinenno, Frank A ^b   Dietz, Niki M ^b  

^a UNIVERSITY OF OREGON   (United States)

^b DEPARTMENT OF UROLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ADRENERGIC RECEPTOR STIMULATING AGENT; CLONIDINE; PHENYLEPHRINE;

ADULT; ALPHA ADRENERGIC STIMULATION; ARTERIAL PRESSURE; ARTICLE; BLOOD PRESSURE MEASUREMENT; BRACHIAL ARTERY; CONTROLLED STUDY; CYCLING; DOPPLER FLOWMETER; FEMALE; FEMORAL ARTERY; FOREARM BLOOD FLOW; HUMAN; HUMAN EXPERIMENT; HYPOTENSION; LEG BLOOD FLOW; MALE; MUSCLE EXERCISE; NORMAL HUMAN; PLETHYSMOGRAPHY; PRIORITY JOURNAL; VASOCONSTRICTION; VASODILATATION; ALPHA ADRENERGIC VASCULAR RESPONSIVENESS; ARTERY CATHETER; BLOOD VESSEL REACTIVITY; CONDUCTANCE; DOPPLER FLOWMETRY; EXERCISE; MEAN ARTERIAL PRESSURE; POST EXERCISE HYPOTENSION; VASCULARIZATION;

ADRENERGIC ALPHA-AGONISTS; ADULT; BICYCLING; BLOOD PRESSURE; BLOOD VESSELS; CLONIDINE; EXERCISE; FEMALE; FOREARM; HUMANS; HYPOTENSION; LEG; MALE; PHENYLEPHRINE; REGIONAL BLOOD FLOW;

EID: 0037592211     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2003.042838     Document Type: Article

References (51)

1. 2-adrenoreceptor constriction to metabolic inhibition during rat skeletal muscle contraction. Circ Res 69, 174-184.
2. Birch K, Cable N & George K (2002). Combined oral contraceptives do not influence post-exercise hypotension in women. Exp Physiol 87, 623-632.
3. Boone JB Jr, Levine M, Flynn MG, Pizza FX, Kubitz ER & Andres FF (1992). Opioid receptor modulation of postexercise hypotension. Med Sci Sports Exer 24, 1108-1113.
4. 1-Adrenergic-receptor responsiveness in skeletal muscle during dynamic exercise. J Appl Physiol 85, 2277-2283.
5. Buckwalter JB, Naik JS, Valic Z & Clifford PS (2001). Exercise attenuates α-adrenergic-receptor responsiveness in skeletal muscle vasculature. J Appl Physiol 90, 172-178.
6. Cléroux J, Kouamé N, Nadeau A, Coulombe D & Lacourcière Y (1992a). Aftereffects of exercise on regional and systemic hemodynamics in hypertension. Hypertension 19, 183-191.
7. Cléroux J, Kouamé N, Nadeau A, Coulombe D & Lacourcière Y (1992b). Baroreflex regulation of forearm vascular resistance after exercise in hypertensive and normotensive humans. Am J Physiol 263, H1523-1531.
8. Coats AJS, Conway J, Isea JE, Pannarale G, Sleight P & Somers VK (1989). Systemic and forearm vascular resistance changes after upright bicycle exercise in man. J Physiol 413, 289-298.
9. Devine MD, Sebastian LA, Monnin KA & Tipton CM (1991). Training and post-exercise hypotension with hypertensive rats (SHR). Physiol 34, 267.
10. Dietz NM, Rivera JM, Eggener SE, Fix RT, Warner DO & Joyner MJ (1994a). Nitric oxide contributes to the rise in forearm blood flow during mental stress in humans. J Physiol 480, 361-368.
11. Dietz NM, Rivera JM, Warner DO & Joyner MJ (1994b). Is nitric oxide involved in cutaneous vasodilation during body heating in humans? J Appl Physiol 76, 2047-2053.
12. Dinenno FA, Eisenach JH, Dietz NM & Joyner MJ (2002). Post-junctional α-adrenoceptors and basal limb vascular tone in healthy men. J Physiol 540, 1103-1110.
13. Floras JS, Sinkey CA, Aylward PE, Seals DR, Thoren PN & Mark AL (1989). Postexercise hypotension and sympathoinhibition in borderline hypertensive men. Hypertension 14, 28-35.
14. Gonzalez C, Fernandez A, Martin C, Moncada S & Estrada C (1992). Nitric oxide from endothelium and smooth muscle modulates responses to sympathetic nerve stimulation: implications for endotoxin shock. Biochem Biophys Res Commun 186, 150-156.
15. Greenfield ADM, Whitney RJ & Mowbray JF (1963). Methods for the investigation of peripheral blood flow. Br Med Bull 19, 101-109.
16. Halliwill JR (2001). Mechanisms and clinical implications of post-exercise hypotension in humans. Exerc Sport Sci Rev 29, 65-70.
17. Halliwill JR, Minson CT & Joyner MJ (2000). Effect of systemic nitric oxide synthase inhibition on postexercise hypotension in humans. J Appl Physiol 89, 1830-1836.
18. Halliwill JR, Taylor JA & Eckberg DL (1996a). Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J Physiol 495, 279-288.
19. Halliwill JR, Taylor JA, Hartwig TD & Eckberg DL (1996b). Augmented baroreflex heart rate gain after moderate-intensity, dynamic exercise. Am J Physiol 270, R420-426.
20. Hannum SM & Kasch FW (1981). Acute postexercise blood pressure response of hypertensive and normotensive men. Scand J Sports Sci 3, 11-15.
21. Hara K & Floras JS (1992). Effects of naloxone on hemodynamics and sympathetic activity after exercise. J Appl Physiol 73, 2028-2035.
22. Howard MG & DiCarlo SE (1992). Reduced vascular responsiveness after a single bout of dynamic exercise in the conscious rabbit. J Appl Physiol 73, 2662-2667.
23. Howard MG, DiCarlo SE & Stallone JN (1992). Acute exercise attenuates phenylephrine-induced contraction of rabbit isolated aortic rings. Med Sci Sports Exerc 24, 1102-1107.
24. Iida N (1999). Nitric oxide mediates sympathetic vasoconstriction at supraspinal, spinal, and synaptic levels. Am J Physiol 276, H918-H925.
25. Isea JE, Piepoli M, Adamopoulos S, Pannarale G, Sleight P & Coats AJS (1994). Time course of haemodynamic changes after maximal exercise. Eur J Clin Invest 24, 824-829.
26. 2-adrenoceptors in man. Circ Res 54, 447-452.
27. 2-adrenoceptors in human blood vessels: interactions with exogenous and endogenous catecholamines. Eur J Clin Invest 17, 174-181.
28. Kaufman FL, Hughson RL & Schaman JP (1987). Effect of exercise on recovery blood pressure in normotensive and hypertensive subjects. Med Sci Sport Exerc 19, 17-20.
29. 2-adrenoceptors and norepinephrine release in the forearm of normal humans. J Cardiovasc Pharm 7, S144-S148.
30. Kulics JM, Collins HL & DiCarlo SE (1999). Postexercise hypotension is mediated by reductions in sympathetic nerve activity. Am J Physiol 276, H27-32.
31. Landry JF, Després JP, Prud'homme D, Lamarche B, Tremblay A, Nadeau A & Bouchard C (1992). A study of some potential correlates of the hypotensive effects of prolonged submaximal exercise in normotensive men. Can J Physiol Pharmacol 70, 53-59.
32. 3H-noradrenaline and the contractile response evoked by field stimulation, in rat vas deferens. Acta Physiol Scand 120, 477-479.
33. Martin WH III, Spina RJ, Korte E & Ogawa T (1991). Effects of chronic and acute exercise on cardiovascular β-adrenergic responses. J Appl Physiol 71, 1523-1528.
34. Patil RD, DiCarlo SE & Collins HL (1993). Acute exercise enhances nitric oxide modulation of vascular response to phenylephrine. Am J Physiol 265, H1184-1188.
35. Pernow J, Lundberg JM, Kaijser L, Hjemdahl P, Theodorsson-Norheim E, Martinsson A & Pernow B (1986). Plasma neuropeptide Y-like immunoreactivity and catecholamines during various degrees of sympathetic activation in man. Clin Physiol 6, 561-578.
36. Piepoli M, Isea JE, Pannarale G, Adamopoulos S, Sleight P & Coats AJS (1994). Load dependence of changes in forearm and peripheral vascular resistance after acute leg exercise in man. J Physiol 478, 357-362.
37. Pohl U & DeWit C (1996). Interaction of nitric oxide with myogenic and adrenergic vasoconstrictor processes in the control of microcirculatory blood flow. Plugers Arch 432, R107-110.
38. Rao SP, Collins HL & DiCarlo SE (2002). Postexercise α-adrenergic receptor hyporesponsiveness in hypertensive rats is due to nitric oxide. Am J Physiol Regul Integr Comp Physiol 282, R960-968.
39. Robertson D, Johnson GA, Robertson RM, Nies AS, Shand DG & Oates JA (1979). Comparative assessment of stimuli that release neuronal and adrenomedullary catecholamines in man. Circulation 59, 637-643.
40. 2-adrenergic vasoconstriction is blunted in contracting human muscle. J Physiol 547, 971-976.
41. Schwarz L & Kindermann W (1992). Changes in β-endorphin levels in response to aerobic and anaerobic exercise. Sports Med 13, 25-36.
42. Sebastian LA, Moran MM & Tipton CM (1995). Post-exercise hypotension and intra-cerebro-ventricular (ICV) injections of β-endorphin and naloxone hydrochloride. FASEB J 9, A361.
43. Senitko AN, Charkoudian N & Halliwill JR (2002). Influence of endurance exercise training status and gender on postexercise hypotension. J Appl Physiol 92, 2368-2374.
44. Shyu BC & Thorén P (1986). Circulatory events following spontaneous muscle exercise in normotensive and hypertensive rats. Acta Physiol Scand 128, 515-524.
45. Somers VK, Conway J, Coats A, Isea J & Sleight P (1991). Postexercise hypotension is not sustained in normal and hypertensive humans. Hypertension 18, 211-215.
46. 2-adrenergic vasoconstriction during contraction of glycolytic, not oxidative, rat himblimb muscle. Am J Physiol 266, H920-929.
47. Thomas GD & Victor RG (1997). Nitric oxide mediates contraction-induced attenuation of sympathetic vasoconstriction in rat skeletal muscle. J Physiol 506, 817-826.
48. Torp KD, Tschakovsky ME, Halliwill JR, Minson CT & Joyner MJ (2001). β-receptor agonist activity of phenylephrine in the human forearm. J Appl Physiol 90, 1855-1859.
49. Tschakovsky ME, Sujirattanawimol K, Ruble SB, Valic Z & Joyner MJ (2002). Is sympathetic neural vasoconstriction blunted in the vascular bed of exercising human muscle? J Physiol 541, 623-635.
50. Wilcox RG, Bennett T, Brown AM & Macdonald IA (1982). Is exercise good for high blood pressure? Br Med J 285, 767-769.
51. Wong-Dusting H & Rand MJ (1989). Inhibition of sympathetic neurotransmission by the opioid δ-receptor agonist DAMA in the pithed rat. Clin Exp Pharmacol Physiol 16, 821-827.