Postexercise hypotension is mediated by reductions in sympathetic nerve activity

American Journal of Physiology - Heart and Circulatory Physiology

Volumn 276, Issue 1 45-1, 1999, Pages

  Kulics, Jennifer M ^a   Collins, Heidi L ^a   DiCarlo, Stephen E ^a  

^a WAYNE STATE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Blood pressure; Exercise; Hypertension; Postexertional hypotension

Indexed keywords

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; ESSENTIAL HYPERTENSION; EXERCISE; HEART OUTPUT; HYPOTENSION; MALE; MEAN ARTERIAL PRESSURE; NONHUMAN; PHYSICAL STRESS; PRIORITY JOURNAL; RAT; SPONTANEOUSLY HYPERTENSIVE RAT; SYMPATHETIC NERVE; VASCULAR RESISTANCE;

EID: 0032957696     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.1999.276.1.h27     Document Type: Article

References (29)

1. Bennett, T., R. G. Wilcox, and I. A. MacDonald. Post-exercise reduction of blood pressure in hypertensive men is not due to acute impairment of baroreflex function. Clin. Sci. 67: 97-103, 1984.
2. Billman, G. E., P. J. Schwartz, and H. L. Stone. The effects of daily exercise on susceptibility to sudden cardiac death. Circulation 69: 1182-1189, 1984.
3. Buñag, R. D., and K. Takeda. Sympathetic hyperresponsiveness to hypothalamic stimulation in young hypertensive rats. Am. J. Physiol. 237 (Regulatory Integrative Comp. Physiol. 6): R39-R44, 1979.
4. Chandler, M. P., and S. E. DiCarlo. Sinoaortic denervation prevents postexercise reductions in arterial pressure and cardiac sympathetic tonus. Am. J. Physiol. 273 (Heart Circ. Physiol. 42): H2738-H2745, 1997.
5. Chandler, M. P., and S. E. DiCarlo. Acute exercise and gender alter cardiac autonomic tonus differently in hypertensive and normotensive rats. Am. J. Physiol. 274 (Regulatory Integrative Comp. Physiol. 43): R510-R516, 1998.
6. Cléroux, J., N. Kouamé, A. Nadeau, D. Coulombe, and Y. Lacourciere. Aftereffects of exercise on regional and systemic hemodynamics in hypertension. Hypertension 19: 183-191, 1992.
7. Cléroux, J., N. Kouamé, A. Nadeau, D. Coulombe, and Y. Lacourciere. Baroreflex regulation of forearm vascular resistance after exercise in hypertensive and normotensive humans. Am. J. Physiol. 263 (Heart Circ. Physiol. 32): H1523-H1531, 1992.
8. Coats, A. J. S., J. Conway, J. E. Isea, G. Pannarale, P. Sleight, and V. K. Somers. Systemic and forearm vascular-resistance changes after upright bicycle exercise in man. J. Physiol. (Lond.) 413: 289-298, 1989.
9. Collins, H. L., and S. E. DiCarlo. Attenuation of postexertional hypotension by cardiac afferent blockade. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H1179-H1183, 1993.
10. DiCarlo, S. E., H. L. Collins, M. G. Howard, C. Y. Chen, T. J. Scislo, and R. D. Patil. Postexertional hypotension: a brief review. Sports Med. Training Rehab. 5: 17-27, 1994.
11. Floras, J. S., C. A. Sinkey, P. E. Aylward, D. R. Seals, P. N. Thorén, and A. L. Mark. Postexercise hypotension and sympathoinhibition in borderline hypertensive men. Hypertension 14: 28-35, 1989.
12. Hagberg, J. M., S. J. Montain, and W. H. Martin. Blood pressure and hemodynamic responses after exercise in older hypertensive men. J. Appl. Physiol. 63: 270-276, 1987.
13. Halliwill, J. R., J. A. Taylor, and D. L. Eckberg. Impaired sympathetic vascular regulation in humans after acute dynamic exercise. J. Physiol. (Lond.) 495: 279-288, 1996.
14. Hara, K., and J. S. Floras. Effects of naloxone on hemodynamics and sympathetic activity after exercise. J. Appl. Physiol. 73: 2028-2035, 1992.
15. Hara, K., and J. S. Floras. Influence of naloxone on muscle sympathetic nerve activity, systemic and calf hemodynamics and ambulatory blood pressure after exercise in mild essential hypertension. J. Hypertens. 13: 447-461, 1995.
16. Haywood, J. R., R. A. Shaffer, C. Fastenow, G. D. Fink, and M. J. Brody. Regional blood flow measurement with pulsed Doppler flowmeter in conscious rat. Am. J. Physiol. 241 (Heart Circ. Physiol. 10): H273-H278, 1981.
17. Howard, M. G., S. E. DiCarlo, and J. N. Stallone. Acute exercise attenuates phenylephrine induced contraction of rabbit isolated aortic ring. Med. Sci. Sports Exerc. 24: 1102-1107, 1992.
18. Howard, M. G., and S. E. DiCarlo. Reduced vascular responsiveness following a single bout of dynamic exercise. J. Appl. Physiol. 73: 2662-2667, 1992.
19. Judy, W. V., A. M. Watanabe, D. P. Henry, H. R. Besch, W. R. Murphy, and G. M. Hockel. Sympathetic nerve activity: role in regulation of blood pressure in the spontaneously hypertensive rat. Circ. Res. 38, Suppl. II: II-21-II-29, 1976.
20. Kenney, M. J., and D. R. Seals. Postexercise hypotension: key features, mechanisms, and clinical significance. Hypertension. 22: 653-664, 1993.
21. Overton, J. M., M. J. Joyner, and C. M. Tipton. Reductions in blood pressure after acute exercise by hypertensive rats. J. Appl. Physiol. 64: 748-752, 1988.
22. Patil, R. D., S. E. DiCarlo, and H. L. Collins. Acute exercise enhances EDRF modulation of vascular response to phenylephrine. Am. J. Physiol. 265 (Heart Circ. Physiol. 34): H1184-H1188, 1993.
23. Schwartz, P. J., and H. L. Stone. Left stellectomy in the prevention of ventricular fibrillation caused by acute myocardial ischemia in conscious dogs with anterior myocardial infarction. Circulation 62: 1256-1265, 1980.
24. Schwartz, P. J., and H. L. Stone. The role of the autonomie nervous system in sudden coronary death. Ann. NY Acad. Sci. 382: 162-180, 1982.
25. Schwartz, P. J., H. L. Stone, and A. M. Brown. Effects of unilateral stellate ganglion blockade on the arrhythmias associated with coronary occlusion. Am. Heart J. 92: 589-599, 1976.
26. Shyu, B. C., S. A. Andersson, and P. Thorén. Circulatory responses following low frequency stimulation of the sciatic nerve in anesthetized rats. Acta Physiol. Scand. 121: 97-102, 1984.
27. Somers, V. K., E. A. Anderson, and A. L. Mark. Sympathetic neural mechanisms in human hypertension. Curr. Opin. Nephrol. Hypertens. 2: 96-105, 1993.
28. VanNess, J. M., H. J. Takata, and J. M. Overton. Attenuated blood pressure responsiveness during post-exercise hypotension. Clin. Exp. Hypertens. 18: 891-900, 1996.
29. Yao, T., S. A. Andersson, and P. Thorén. Long-lasting cardiovascular depression induced by acupuncture-like stimulation of the sciatic nerve in unanesthetized spontaneously hypertensive rats. Brain Res. 240: 77-85, 1982.