Can clinically relevant histamine release be accurately diagnosed in anaesthetised patients without plasma histamine measurements? Randomised study with nested sampling aimed to change paradigms

Inflammation Research

Volumn 47, Issue SUPPL. 1, 1998, Pages

  Duda, D ^a   Lorenz, W ^b   Dick, W ^a   Celik, I ^b   Black, A ^c   Healy, M J R ^d   Black, J W ^e  

^a JOHANNES GUTENBERG UNIVERSITY   (Germany)

^b PHILIPPS UNIVERSITY MARBURG   (Germany)

^c BRISTOL ROYAL INFIRMARY   (United Kingdom)

^d LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^e James Black Foundation   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANESTHETIC AGENT; HISTAMINE;

ANAPHYLAXIS; ANESTHESIA; CLINICAL TRIAL; CONFERENCE PAPER; CONTROLLED STUDY; HISTAMINE BLOOD LEVEL; HUMAN; MAJOR CLINICAL STUDY; RANDOMIZED CONTROLLED TRIAL; SURGICAL PATIENT;

ANAPHYLAXIS; ANESTHESIA; ANESTHETICS; BLOOD PRESSURE; HEART RATE; HISTAMINE; HISTAMINE H1 ANTAGONISTS; HISTAMINE H2 ANTAGONISTS; HISTAMINE RELEASE; HUMANS;

EID: 0031892387     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Conference Paper

References (8)

1. Lorenz W. Hypersensitivity reactions induced by anaesthetic drugs and plasma substitutes: Influence of paradigms on incidence and mechanisms. In: Gibson GG, Hubbard R, Parke DV, editors. Immunotoxicology. London: Academic Press, 1983:283-305.
2. Sitter H, Lorenz W, Doenicke A. The clinical and biological signs of histamine release during induction of anaesthesia and preparation of the surgical patient: A farewell party for the classical manifestations of anaphylaxis. Agents Actions 1992; 35 Special Conference Issue: C219-30.
3. Lorenz W, Duda D, Dick W, Sitter H, Doenicke A, Black A, et al. Incidence and clinical importance of perioperative histamine release: Randomised study of volume loading and antihistamines after induction of anaesthesia. Lancet 1994;343:933-40.
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8. Sitter H, Stinner B, Duda D, Menke H, Lorenz W. Model building strategies for risk analysis of perioperative histamine-related cardiorespiratory disturbances. Inflamm Res 1995;44 Suppl 1:S82-3.