메뉴 건너뛰기




Volumn 56, Issue 2, 2000, Pages 167-174

Pharmacokinetics, COX-2 specificity, and tolerability of supratherapeutic doses of rofecoxib in humans

Author keywords

COX 2 specificity; Pharmacokinetics; Rofecoxib

Indexed keywords

CYCLOOXYGENASE 1; CYCLOOXYGENASE 1 INHIBITOR; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; IBUPROFEN; PLACEBO; PROSTAGLANDIN E2; ROFECOXIB; THROMBOXANE B2;

EID: 0034040719     PISSN: 00316970     EISSN: None     Source Type: Journal    
DOI: 10.1007/s002280050736     Document Type: Article
Times cited : (98)

References (27)
  • 1
  • 2
    • 0026730021 scopus 로고
    • Human cyclooxygenase-2 cDNA
    • 2. Hla T, Neilson K (1992) Human cyclooxygenase-2 cDNA. Proc Natl Acad Sci USA 89: 7384-7388
    • (1992) Proc Natl Acad Sci USA , vol.89 , pp. 7384-7388
    • Hla, T.1    Neilson, K.2
  • 3
    • 0026801167 scopus 로고
    • Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells
    • 3. Holtzman MJ, Turk J, Shornick LP (1992) Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells. J Biol Chem 267: 21438-21445
    • (1992) J Biol Chem , vol.267 , pp. 21438-21445
    • Holtzman, M.J.1    Turk, J.2    Shornick, L.P.3
  • 6
    • 0032572519 scopus 로고    scopus 로고
    • The effect of aspirin and nonsteroidal anti-inflammatory drugs on prostaglandins
    • 6. Bjorkman DJ (1998) The effect of aspirin and nonsteroidal anti-inflammatory drugs on prostaglandins. Am J Med 105[suppl 1B]: 8S-12S
    • (1998) Am J Med , vol.105 , Issue.SUPPL. 1B
    • Bjorkman, D.J.1
  • 7
    • 0032076219 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and cyclooxygenase-2. Selectivity of widely used nonsteroidal anti-inflammatory drugs
    • 7. Cryer B, Feldman M (1998) Cyclooxygenase-1 and cyclooxygenase-2. Selectivity of widely used nonsteroidal anti-inflammatory drugs. Am J Med 104: 413-421
    • (1998) Am J Med , vol.104 , pp. 413-421
    • Cryer, B.1    Feldman, M.2
  • 8
    • 0030969888 scopus 로고    scopus 로고
    • Differentiating among nonsteroidal anti-inflammatory drugs by pharmacokinetic and pharmacodynamic profiles
    • 8. Fenner H (1997) Differentiating among nonsteroidal anti-inflammatory drugs by pharmacokinetic and pharmacodynamic profiles. Semin Arthritis Rheum 26[suppl 1]: 28-33
    • (1997) Semin Arthritis Rheum , vol.26 , Issue.SUPPL. 1 , pp. 28-33
    • Fenner, H.1
  • 9
    • 0030982146 scopus 로고    scopus 로고
    • Mechanism of action of aspirin-like drugs
    • 9. Vane JR, Botting RM (1997) Mechanism of action of aspirin-like drugs. Semin Arthritis Rheum 26[suppl 1]: 2-10
    • (1997) Semin Arthritis Rheum , vol.26 , Issue.SUPPL. 1 , pp. 2-10
    • Vane, J.R.1    Botting, R.M.2
  • 10
    • 0031921289 scopus 로고    scopus 로고
    • Scientific rationale for specific inhibition of COX-2
    • 10. Botten WW (1998) Scientific rationale for specific inhibition of COX-2. J Rheumatol 51: 2-7
    • (1998) J Rheumatol , vol.51 , pp. 2-7
    • Botten, W.W.1
  • 11
    • 0028044609 scopus 로고
    • Towards a better aspirin
    • 11. Vane JR (1994) Towards a better aspirin. Nature 367: 215-216
    • (1994) Nature , vol.367 , pp. 215-216
    • Vane, J.R.1
  • 14
    • 0030022032 scopus 로고    scopus 로고
    • A human whole blood assay for the clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors
    • 14. Brideau C, Kargman S, Liu S, Dallob A, Ehrich E, Rodger I, Chan C (1996) A human whole blood assay for the clinical evaluation of biochemical efficacy of cyclooxygenase inhibitors. Inflamm Res 45: 68-74
    • (1996) Inflamm Res , vol.45 , pp. 68-74
    • Brideau, C.1    Kargman, S.2    Liu, S.3    Dallob, A.4    Ehrich, E.5    Rodger, I.6    Chan, C.7
  • 18
    • 0001305554 scopus 로고    scopus 로고
    • MK-0966, A specific COX-2 inhibitor, has clinical efficacy comparable to diclofenac in the treatment of knee and hip osteoarthritis in a 26-week controlled clinical trial
    • 18. Cannon G, Caldwell J, Holt P, Mclean B, Zeng Q, Ehrich E, Seidenberg B, Bolognese J, Daniels B (1998) MK-0966, A specific COX-2 inhibitor, has clinical efficacy comparable to diclofenac in the treatment of knee and hip osteoarthritis in a 26-week controlled clinical trial (abstract 983). Arthritis Rheum 41[suppl]: 196
    • (1998) Arthritis Rheum , vol.41 , Issue.SUPPL. , pp. 196
    • Cannon, G.1    Caldwell, J.2    Holt, P.3    McLean, B.4    Zeng, Q.5    Ehrich, E.6    Seidenberg, B.7    Bolognese, J.8    Daniels, B.9
  • 19
    • 0001305554 scopus 로고    scopus 로고
    • MK-0966, A specific COX-2 inhibitor, has clinical efficacy comparable to diclofenac in the treatment of knee and hip osteoarthritis in a 6-week controlled clinical trial
    • 19. Saag K, Fisher C, McKay J, Ehrich E, Zhao PL, Seidenberg B, Bolognese J, Daniels B (1998) MK-0966, A specific COX-2 inhibitor, has clinical efficacy comparable to diclofenac in the treatment of knee and hip osteoarthritis in a 6-week controlled clinical trial (abstract 984). Arthritis Rheum 41[suppl]: 196
    • (1998) Arthritis Rheum , vol.41 , Issue.SUPPL. , pp. 196
    • Saag, K.1    Fisher, C.2    McKay, J.3    Ehrich, E.4    Zhao, P.L.5    Seidenberg, B.6    Bolognese, J.7    Daniels, B.8
  • 21
    • 0033059318 scopus 로고    scopus 로고
    • Determination of rofecoxib, a cyclooxygenase-2 specific inhibitor, in human plasma using high-performance liquid chromatography with post-column photochemical derivatization and fluorescence detection
    • 21. Woolf E, Matuszewski B (1999) Determination of rofecoxib, a cyclooxygenase-2 specific inhibitor, in human plasma using high-performance liquid chromatography with post-column photochemical derivatization and fluorescence detection. J Chromatogr B Biomed Sci Appl 730: 221-227
    • (1999) J Chromatogr B Biomed Sci Appl , vol.730 , pp. 221-227
    • Woolf, E.1    Matuszewski, B.2
  • 22
    • 0029073404 scopus 로고
    • Renal effects of over-the counter analgesics
    • 22. Whelton A (1995) Renal effects of over-the counter analgesics. J Clin Pharmacol 35: 454-463
    • (1995) J Clin Pharmacol , vol.35 , pp. 454-463
    • Whelton, A.1
  • 23
    • 0027478126 scopus 로고
    • Renal toxicity of non-steroidal anti-inflammatory drugs
    • 23. Murray MD, Brater DC (1993) Renal toxicity of non-steroidal anti-inflammatory drugs. Annu Rev Pharmacol 32: 435-465
    • (1993) Annu Rev Pharmacol , vol.32 , pp. 435-465
    • Murray, M.D.1    Brater, D.C.2
  • 24
    • 0031975062 scopus 로고    scopus 로고
    • Non-steroidal anti-inflammatory drug-induced renal failure: A brief review of the role of cyclo-oxygenase isoforms
    • 24. Venturi CM, Isakson P, Needleman P (1998) Non-steroidal anti-inflammatory drug-induced renal failure: a brief review of the role of cyclo-oxygenase isoforms. Curr Opin Nephrol Hypertens 7: 79-82
    • (1998) Curr Opin Nephrol Hypertens , vol.7 , pp. 79-82
    • Venturi, C.M.1    Isakson, P.2    Needleman, P.3
  • 25
    • 33751335393 scopus 로고    scopus 로고
    • Localisation of cyclo-oxygenase 1 and 2 in adult and fetal human kidney: Implication for renal function
    • 25. Komhoff M, Grone HJ, Klein T, Seybert HW, Nusing RM (1997) Localisation of cyclo-oxygenase 1 and 2 in adult and fetal human kidney: implication for renal function. Am J Physiol 272: F460-F468
    • (1997) Am J Physiol , vol.272
    • Komhoff, M.1    Grone, H.J.2    Klein, T.3    Seybert, H.W.4    Nusing, R.M.5
  • 26
    • 0031679914 scopus 로고    scopus 로고
    • Interspecies differences in renal localization of cyclooxygenase isoforms: Implications in nonsteroidal antiinflammatory drug-related nephrotoxicity
    • 26. Khan K, Venturini CM, Bunch RT, Brassard JA, Koki AT, Morris DL, Trump BF, Maziasz TJ, Alden CL (1998) Interspecies differences in renal localization of cyclooxygenase isoforms: implications in nonsteroidal antiinflammatory drug-related nephrotoxicity. Toxicol Pathol 26: 612-620
    • (1998) Toxicol Pathol , vol.26 , pp. 612-620
    • Khan, K.1    Venturini, C.M.2    Bunch, R.T.3    Brassard, J.A.4    Koki, A.T.5    Morris, D.L.6    Trump, B.F.7    Maziasz, T.J.8    Alden, C.L.9
  • 27
    • 0031868142 scopus 로고    scopus 로고
    • Urinary excretion of 6β-hydroxycortisol as an in vivo marker for CYP3A induction: Applications and recommendations
    • 27. Kovacs SJ, Martin DE, Everitt DE, Patterson SD, Jorkasky DK (1998) Urinary excretion of 6β-hydroxycortisol as an in vivo marker for CYP3A induction: applications and recommendations. Clin Pharmacol Ther 63: 617-622
    • (1998) Clin Pharmacol Ther , vol.63 , pp. 617-622
    • Kovacs, S.J.1    Martin, D.E.2    Everitt, D.E.3    Patterson, S.D.4    Jorkasky, D.K.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.