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Volumn 9, Issue 1-2, 2001, Pages 101-112
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Discovery and development of ML3000
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Author keywords
5 lipoxygenase; 2,2 Dimethyl 6 (4 chlorophenyl) 7 phenyl 2,3 dihydro 1H pyrrolizine 5 yl acetic acid; Anti inflammatory; Cyclooxygenase; Gastrointestinal; Leukotriene; ML3000; NSAID
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Indexed keywords
ANTIINFLAMMATORY AGENT;
ANTIPYRETIC ANALGESIC AGENT;
ANTITHROMBOCYTIC AGENT;
ARACHIDONATE 5 LIPOXYGENASE;
ARACHIDONIC ACID;
BRONCHODILATING AGENT;
DICLOFENAC;
INDOMETACIN;
LEUKOTRIENE;
LICOFELONE;
NONSTEROID ANTIINFLAMMATORY AGENT;
PROSTAGLANDIN;
PROSTAGLANDIN SYNTHASE;
PROSTAGLANDIN SYNTHASE INHIBITOR;
PYRROLIZINE DERIVATIVE;
ANALGESIC ACTIVITY;
ANTIINFLAMMATORY ACTIVITY;
ANTIPYRETIC ACTIVITY;
BRONCHODILATING ACTIVITY;
CLINICAL TRIAL;
CONFERENCE PAPER;
DRUG EFFECT;
DRUG EFFICACY;
DRUG MECHANISM;
DRUG SAFETY;
DRUG STRUCTURE;
ENZYME ACTIVITY;
ENZYME INHIBITION;
GASTROINTESTINAL SYMPTOM;
HUMAN;
INFLAMMATION;
LIVER TOXICITY;
MOUSE;
NONHUMAN;
OSTEOARTHRITIS;
OXIDATION REDUCTION REACTION;
PHASE 3 CLINICAL TRIAL;
PRIORITY JOURNAL;
PROSTAGLANDIN SYNTHESIS;
RAT;
STRUCTURE ACTIVITY RELATION;
STRUCTURE ANALYSIS;
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EID: 0034946179
PISSN: 09254692
EISSN: None
Source Type: Journal
DOI: 10.1163/156856001300248371 Document Type: Conference Paper |
Times cited : (55)
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References (22)
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