A hypothesis for the chemical basis for perception of sour taste

Journal of Food Science

Volumn 70, Issue 2, 2005, Pages

  Johanningsmeier, Suzanne D ^a   McFeeters, Roger F ^a   Drake, MaryAnne ^a  

^a NORTH CAROLINA STATE UNIVERSITY   (United States)

Author keywords

Acids; Organic; Protonated; Sour taste; Undissociated

Indexed keywords

EID: 14844336345     PISSN: 00221147     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1365-2621.2005.tb07111.x     Document Type: Article

References (34)

1. Bachmanov A, Beauchamp GK. 2002. Genetic dissection of sweet taste. American Chemical Society, Washington, D.C. In: 224th American Chemical Society Natl. Meeting; Boston; 2002 Aug 18-22. Abstr. nr 6.
2. Corrigan-Thomas CJ, Lawless HT. 1995. Astringent subqualities in acids. Chem Senses 20:593-600.
3. CoSeteng MY, McLellan MR, Downing DL. 1989. Influence of titratable acidity and pH on intensity of sourness of citric, malic, tartaric, lactic and acetic acid solutions and on the overall acceptability of imitation apple juice. Can Inst Food Sci Technol J 22:46-51.
4. DeSimone JA, Lyall V, Heck GL, Feldman GM. 2001. Acid detection by taste receptor cells. Resp Physiol 129:231-45.
5. Dougherty DP. 2002. Deterministic and semi-mechanistic approaches in predictive fermentation microbiology [DPhil dissertation]. Raleigh, N.C.: N.C. State Univ.
6. Ganzevles PGJ, Kroeze JHA. 1987. The sour taste of acids. The hydrogen ion and the undissociated acid as sour agents. Chem Senses 12:563-76.
7. Gardner RJ. 1980. Lipid solubility and the sourness of acids: implications for models of the acid taste receptor. Chem Senses Flav 5:185-94.
8. Hartwig P, McDaniel MR. 1995. Flavor characteristics of lactic, malic, citric and acetic acids at various pH levels. J Food Sci 60(2):384-8.
9. Harvey RB. 1920. The relation between the total acidity, the concentration of the hydrogen ion, and the taste of acid solutions. J Am Chem Soc 42:712-4.
10. Herness MS, Gilbertson TA. 1999. Cellular mechanisms of taste transduction. Ann Rev Physiol 61:873-900.
11. Johanningsmeier SD, Fleming HP, Thompson RL, McFeeters RF. Chemical and sensory properties of sauerkraut produced with Leuconostoc mesenteroides starter cultures of differing malolactic phenotypes. Submitted 2004.
12. Johanningsmeier SD, Thompson RL, Fleming, HP. 2003. Bag-in-box technology: sensory quality of pickles produced from process-ready, fermented cucumbers. Pickle Pak Sci 8(1):26-33.
13. Lawless HT, Horne J, Giasi P. 1996. Astringency of organic acids is related to pH. Chem Senses 21:397-403.
14. Li X, Inoue M, Reed DR, Huque T, Puchalski RB, Tordoff MG, Ninomiya Y, Beauchamp GK, Bachmanov AA. 2001. High resolution genetic mapping of the saccharin preference locus (Sac) and putative sweet taste receptor (T1R1) gene (Gpr70) to mouse distal chromosome 4. Mam Gen 12:13-6.
15. Li X, Staszewski L, Xu H, Durick K, Zoller M, Adler E. 2002. Human receptors for sweet and umami taste. Proc Nat Acad Sci USA 99:4692-6.
16. Lin W, Ogura T, Kinnamon SC. 2002. Acid-activated cation currents in rat vallate taste receptor cells. J Neurophysiol 88:133-41.
17. Lyall V, Rammy IA, Phan DQ, Ereso GL, Phan THT, Malik SA, Montrose MH, Chu S, Heck GL, Feldman GM, DeSimone JA. 2001. Decrease in rat taste receptor cell intracellular pH is the proximate stimulus in sour taste transduction. Am J Physiol Cell Physiol 281:C1005-13.
18. Margolskee RF. 2002. Molecular mechanisms of better and sweet taste transduction. J Biol Chem 277:1-4.
19. McFeeters RF. 1993. Single-injection HPLC analysis of acids, sugars, and alcohols in cucumber fermentations. J Agric Food Chem 41(9):1439-43.
20. Montmayeur JP, Liberles SD, Matsunami H, Buck LB. 2001. A candidate taste receptor gene near a sweet taste locus. Nat Neurosci 4:492-8.
21. Nelson G, Hoon MA, Chandrashekar J, Zhang Y, Ryba NJ, Zuker CS. 2001. Mammalian sweet taste receptors. Cell 106(3):381-90.
22. Noble AC, Philbrick KC, Boulton RB. 1986. Comparison of sourness of organic acid anions at equal pH and equal titratable acidity. J Sens Stud 1:1-8.
23. Ogiso K, Shimizu Y, Watanabe K, Tonosaki K. 2000. Possible involvement of undissociated acid molecules in the acid response of the chorda tympani nerve of the rat. J Neurophysiol 83:2776-9.
24. Pangborn RM. 1963. Relative taste intensities of selected sugars and organic acids. J Food Sci 28:726-33.
25. Plane RA, Mattick LR, LaVerne DW. 1980. An acidity index for the taste of wines. Am J Enol Vitic 31:265-8.
26. 2+ and pH responses in mouse taste cells. Journal of Physiology 547(2):475-83.
27. Rubico SM, McDaniel MR. 1992. Sensory evaluation of acids by free-choice profiling. Chem Sen 17:273-89.
28. Ruiz AL, Wong GT, Damak S, Margolskee RF. 2001. Dominant loss of responsiveness to sweet and bitter compounds caused by a single mutation in alpha-gusducin. Proc Nat Acad Sci USA 98:8868-73.
29. Samson E, Lemaire G, Marchand J, Beaudoin J. 1999. Modeling chemical activity effects in strong ionic solutions. Comp Mater Sci 15:285-94.
30. Shallenberger RS. 1996. The AH,B glycophore and general taste chemistry. Food Chem 56:209-14.
31. Sowalsky RA, Noble AC. 1998. Comparison of the effects of concentration, pH and anion species on astringency and sourness of organic acids. Chem Sen 23:343-9.
32. Stewart RE, DeSimone JA, Hill DL. 1997. New perspectives in gustatory physiology: transduction, development, and plasticity. Am J Physiol Cell Physiol 272:C1-C26.
33. Zhang Y, Hoon MA, Chandrashekar J, Mueller KL, Cook B, Wu D, Zuker CS, Ryba JP. 2003. Coding of sweet, bitter, and umami tastes: different receptor cells snaring similar signaling pathways. Cell 112(3):293-301.
34. Zhao GQ, Zhang Y, Hoon MA, Chandrashekar J, Erlenbach I, Ryba NJP, Zuker CS. 2003. The receptors for mammalian sweet and umami taste. Cell 115(3):255-66.