메뉴 건너뛰기




Volumn 19, Issue 3, 2005, Pages 749-758

Evidence that palmitoylation of carboxyl terminus cysteine residues of the human luteinizing hormone receptor regulates postendocytic processing

Author keywords

[No Author keywords available]

Indexed keywords

CYSTEINE; G PROTEIN COUPLED RECEPTOR; GLYCINE; LUTEINIZING HORMONE RECEPTOR; MUTANT PROTEIN; PALMITIC ACID;

EID: 14844291405     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2004-0335     Document Type: Article
Times cited : (34)

References (30)
  • 1
    • 1642268837 scopus 로고    scopus 로고
    • Regulation of luteinizing hormone/human chorionic gonadotropin receptor expression: A perspective
    • Menon K, Munshi U, Clouser C, Nair A 2004 Regulation of luteinizing hormone/human chorionic gonadotropin receptor expression: a perspective. Biol Reprod 70: 861-866
    • (2004) Biol Reprod , vol.70 , pp. 861-866
    • Menon, K.1    Munshi, U.2    Clouser, C.3    Nair, A.4
  • 3
    • 0036217072 scopus 로고    scopus 로고
    • The lutropin/choriogonadotropin receptor, a 2002 perspective
    • Ascoli M, Fanelli F, Segaloff DL 2002 The lutropin/ choriogonadotropin receptor, a 2002 perspective. Endocr Rev 23:141-174
    • (2002) Endocr Rev , vol.23 , pp. 141-174
    • Ascoli, M.1    Fanelli, F.2    Segaloff, D.L.3
  • 4
    • 0030948572 scopus 로고    scopus 로고
    • The six N-linked carbohydrates of the lutropin/choriogonadotropin receptor are not absolutely required for correct folding, cell surface expression, hormone binding, or signal transduction
    • Davis DP, Rozell TG, Liu X, Segaloff DL 1997 The six N-linked carbohydrates of the lutropin/choriogonadotropin receptor are not absolutely required for correct folding, cell surface expression, hormone binding, or signal transduction. Mol Endocrinol 11:550-562
    • (1997) Mol Endocrinol , vol.11 , pp. 550-562
    • Davis, D.P.1    Rozell, T.G.2    Liu, X.3    Segaloff, D.L.4
  • 5
    • 0029094166 scopus 로고
    • Functional glycosylation sites of the rat luteinizing hormone receptor required for ligand binding
    • Zhang R, Cai H, Fatima N, Buczko E, Dufau ML 1995 Functional glycosylation sites of the rat luteinizing hormone receptor required for ligand binding. J Biol Chem 270:21722-21728
    • (1995) J Biol Chem , vol.270 , pp. 21722-21728
    • Zhang, R.1    Cai, H.2    Fatima, N.3    Buczko, E.4    Dufau, M.L.5
  • 6
    • 0027999333 scopus 로고
    • Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells. Abolition of palmitoylation by mutation of Cys-621 and Cys-622 residues in the cytoplasmic tail increases ligand-induced internalization of the receptor
    • Kawate N, Menon KM 1994 Palmitoylation of luteinizing hormone/human choriogonadotropin receptors in transfected cells. Abolition of palmitoylation by mutation of Cys-621 and Cys-622 residues in the cytoplasmic tail increases ligand-induced internalization of the receptor. J Biol Chem 269:30651-30658
    • (1994) J Biol Chem , vol.269 , pp. 30651-30658
    • Kawate, N.1    Menon, K.M.2
  • 7
    • 0028809315 scopus 로고
    • Human chorionic gonadotropin (CG)- and phorbol ester-stimulated phosphorylation of the luteinizing hormone/CG receptor maps to serines 635, 639, 649, and 652 in the C-terminal cytoplasmic tail
    • Hipkin RW, Wang Z, Ascoli M 1995 Human chorionic gonadotropin (CG)- and phorbol ester-stimulated phosphorylation of the luteinizing hormone/CG receptor maps to serines 635, 639, 649, and 652 in the C-terminal cytoplasmic tail. Mol Endocrinol 9:151-158
    • (1995) Mol Endocrinol , vol.9 , pp. 151-158
    • Hipkin, R.W.1    Wang, Z.2    Ascoli, M.3
  • 8
    • 0038757730 scopus 로고    scopus 로고
    • Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function
    • Qanbar R, Bouvier M 2003 Role of palmitoylation/depalmitoylation reactions in G-protein-coupled receptor function. Pharmacol Ther 97:1-33
    • (2003) Pharmacol Ther , vol.97 , pp. 1-33
    • Qanbar, R.1    Bouvier, M.2
  • 9
    • 0024544232 scopus 로고
    • Palmitoylation of the human β2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor
    • O'Dowd B, Hnatowich M, Caron M, Lefkowitz R, Bouvier M 1989 Palmitoylation of the human β2-adrenergic receptor. Mutation of Cys341 in the carboxyl tail leads to an uncoupled nonpalmitoylated form of the receptor. J Biol Chem 264:7564-7569
    • (1989) J Biol Chem , vol.264 , pp. 7564-7569
    • O'Dowd, B.1    Hnatowich, M.2    Caron, M.3    Lefkowitz, R.4    Bouvier, M.5
  • 10
    • 0035860777 scopus 로고    scopus 로고
    • Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization
    • Kraft K, Olbrich H, Majoul I, Mack M, Proudfoot A, Oppermann M 2001 Characterization of sequence determinants within the carboxyl-terminal domain of chemokine receptor CCR5 that regulate signaling and receptor internalization. J Biol Chem 276:34408-34418
    • (2001) J Biol Chem , vol.276 , pp. 34408-34418
    • Kraft, K.1    Olbrich, H.2    Majoul, I.3    Mack, M.4    Proudfoot, A.5    Oppermann, M.6
  • 11
    • 0028872763 scopus 로고
    • The lutropin/choriogonadotropin receptor is palmitoylated at intracellular cysteine residues
    • Zhu H, Wang H, Ascoli M 1995 The lutropin/choriogonadotropin receptor is palmitoylated at intracellular cysteine residues. Mol Endocrinol 9:141-150
    • (1995) Mol Endocrinol , vol.9 , pp. 141-150
    • Zhu, H.1    Wang, H.2    Ascoli, M.3
  • 12
    • 0030889243 scopus 로고    scopus 로고
    • Role of palmitoylation of conserved cysteine residues of luteinizing hormone/human choriogonadotropin receptors in receptor down-regulation
    • Kawate N, Peegel H, Menon KM 1997 Role of palmitoylation of conserved cysteine residues of luteinizing hormone/human choriogonadotropin receptors in receptor down-regulation. Mol Cell Endocrinol 127:211-219
    • (1997) Mol Cell Endocrinol , vol.127 , pp. 211-219
    • Kawate, N.1    Peegel, H.2    Menon, K.M.3
  • 13
    • 0034825632 scopus 로고    scopus 로고
    • Palmitoylation of the luteinizing hormone/human chorionic gonadotropin receptor regulates receptor interaction with the arrestin-mediated internalization pathway
    • Munshi UM, Peegel H, Menon KM 2001 Palmitoylation of the luteinizing hormone/human chorionic gonadotropin receptor regulates receptor interaction with the arrestin-mediated internalization pathway. Eur J Biochem 268: 1631-1639
    • (2001) Eur J Biochem , vol.268 , pp. 1631-1639
    • Munshi, U.M.1    Peegel, H.2    Menon, K.M.3
  • 14
    • 0034823954 scopus 로고    scopus 로고
    • Identification of two distinct structural motifs that, wh.en added to the C-terminal tail of the rat LH receptor, redirect the internalized hormone-receptor complex from a degradation to a recycling pathway
    • Kishi M, Liu X, Hirakawa T, Reczek D, Bretscher A, Ascoli M 2001 Identification of two distinct structural motifs that, when added to the C-terminal tail of the rat LH receptor, redirect the internalized hormone-receptor complex from a degradation to a recycling pathway. Mol Endocrinol 15:1624-1635
    • (2001) Mol Endocrinol , vol.15 , pp. 1624-1635
    • Kishi, M.1    Liu, X.2    Hirakawa, T.3    Reczek, D.4    Bretscher, A.5    Ascoli, M.6
  • 15
    • 0037341727 scopus 로고    scopus 로고
    • Identification of a transferable two-amino-acid motif (GT) present in the C-terminal tail of the human lutropin receptor that redirects internalized G protein-coupled receptors from a degradation to a recycling pathway
    • Galet C, Min L, Narayanan R, Kishi M, Weigel NL, Ascoli M 2003 Identification of a transferable two-amino-acid motif (GT) present in the C-terminal tail of the human lutropin receptor that redirects internalized G protein-coupled receptors from a degradation to a recycling pathway. Mol Endocrinol 17:411-422
    • (2003) Mol Endocrinol , vol.17 , pp. 411-422
    • Galet, C.1    Min, L.2    Narayanan, R.3    Kishi, M.4    Weigel, N.L.5    Ascoli, M.6
  • 16
    • 0842292006 scopus 로고    scopus 로고
    • GIPC binds to the human lutropin receptor (LHR) through an unusual PDZ domain binding motif and it regulates the sorting of the internalized human choriogonadotropin (hCG) and the density of cell surface LHR
    • Hirakawa T, Galet C, Kishi M, Ascoli M 2003 GIPC binds to the human lutropin receptor (LHR) through an unusual PDZ domain binding motif and it regulates the sorting of the internalized human choriogonadotropin (hCG) and the density of cell surface LHR. J Biol Chem 278: 49348-49357
    • (2003) J Biol Chem , vol.278 , pp. 49348-49357
    • Hirakawa, T.1    Galet, C.2    Kishi, M.3    Ascoli, M.4
  • 17
    • 0842290983 scopus 로고    scopus 로고
    • The postendocytotic trafficking of the human lutropin receptor is mediated by a transferable motif consisting of the C-terminal cysteine and an upstream leucine
    • Galet C, Hirakawa T, Ascoli M 2004 The postendocytotic trafficking of the human lutropin receptor is mediated by a transferable motif consisting of the C-terminal cysteine and an upstream leucine. Mol Endocrinol 18:434-446
    • (2004) Mol Endocrinol , vol.18 , pp. 434-446
    • Galet, C.1    Hirakawa, T.2    Ascoli, M.3
  • 18
    • 0031046907 scopus 로고    scopus 로고
    • Post-translational processing in the Golgi plays a critical role in the trafficking of the luteinizing hormone/human chorionic gonadotropin receptor to the cell surface
    • Bradbury FA, Kawate N, Foster CM, Menon KM 1997 Post-translational processing in the Golgi plays a critical role in the trafficking of the luteinizing hormone/human chorionic gonadotropin receptor to the cell surface. J Biol Chem 272:5921-5926
    • (1997) J Biol Chem , vol.272 , pp. 5921-5926
    • Bradbury, F.A.1    Kawate, N.2    Foster, C.M.3    Menon, K.M.4
  • 19
    • 0033645593 scopus 로고    scopus 로고
    • Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor
    • Min L, Ascoli M 2000 Effect of activating and inactivating mutations on the phosphorylation and trafficking of the human lutropin/choriogonadotropin receptor. Mol Endocrinol 14:1797-1810
    • (2000) Mol Endocrinol , vol.14 , pp. 1797-1810
    • Min, L.1    Ascoli, M.2
  • 20
    • 0032567352 scopus 로고    scopus 로고
    • Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor
    • Min KS, Liu X, Fabritz J, Jaquette J, Abell AN, Ascoli M 1998 Mutations that induce constitutive activation and mutations that impair signal transduction modulate the basal and/or agonist-stimulated internalization of the lutropin/choriogonadotropin receptor. J Biol Chem 273: 34911-34919
    • (1998) J Biol Chem , vol.273 , pp. 34911-34919
    • Min, K.S.1    Liu, X.2    Fabritz, J.3    Jaquette, J.4    Abell, A.N.5    Ascoli, M.6
  • 22
    • 0037163045 scopus 로고    scopus 로고
    • Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking
    • Kim Y-M, Benovic JL 2002 Differential roles of arrestin-2 interaction with clathrin and adaptor protein 2 in G protein-coupled receptor trafficking. J Biol Chem 277: 30760-30768
    • (2002) J Biol Chem , vol.277 , pp. 30760-30768
    • Kim, Y.-M.1    Benovic, J.L.2
  • 23
    • 0036209874 scopus 로고    scopus 로고
    • Endocytosis of G protein-coupled receptors: Roles of G protein-coupled receptor kinases and β-arrestin proteins
    • Claing A, Laporte SA, Caron MG, Lefkowitz RJ 2002 Endocytosis of G protein-coupled receptors: roles of G protein-coupled receptor kinases and β-arrestin proteins. Prog Neurobiol 66:61-79
    • (2002) Prog Neurobiol , vol.66 , pp. 61-79
    • Claing, A.1    Laporte, S.A.2    Caron, M.G.3    Lefkowitz, R.J.4
  • 24
    • 0242384217 scopus 로고    scopus 로고
    • Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway
    • von Zastrow M 2003 Mechanisms regulating membrane trafficking of G protein-coupled receptors in the endocytic pathway. Life Sci 74:217-224
    • (2003) Life Sci , vol.74 , pp. 217-224
    • Von Zastrow, M.1
  • 25
    • 0029103106 scopus 로고
    • Dynamic regulation of G-protein coupled receptor palmitoylation: Potential role in receptor function
    • Bouvier M, Loisel TP, Hebert T 1995 Dynamic regulation of G-protein coupled receptor palmitoylation: potential role in receptor function. Biochem Soc Trans 23:577-581
    • (1995) Biochem Soc Trans , vol.23 , pp. 577-581
    • Bouvier, M.1    Loisel, T.P.2    Hebert, T.3
  • 26
    • 0029753014 scopus 로고    scopus 로고
    • Agonist stimulation increases the turnover rate of β 2AR-bound palmitate and promotes receptor depalmitoylation
    • Loisel TP, Adam L, Hebert TE, Bouvier M 1996 Agonist stimulation increases the turnover rate of β 2AR-bound palmitate and promotes receptor depalmitoylation. Biochemistry 35:15923-15932
    • (1996) Biochemistry , vol.35 , pp. 15923-15932
    • Loisel, T.P.1    Adam, L.2    Hebert, T.E.3    Bouvier, M.4
  • 27
    • 0034006037 scopus 로고    scopus 로고
    • Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor
    • Palmer TM, Stiles GL 2000 Identification of threonine residues controlling the agonist-dependent phosphorylation and desensitization of the rat A3 adenosine receptor. Mol Pharmacol 57:539-545
    • (2000) Mol Pharmacol , vol.57 , pp. 539-545
    • Palmer, T.M.1    Stiles, G.L.2
  • 29
    • 0033529237 scopus 로고    scopus 로고
    • Evidence that constitutively active luteinizing hormone/human chorionic gonadotropin receptors are rapidly internalized
    • Bradbury FA, Menon KM 1999 Evidence that constitutively active luteinizing hormone/human chorionic gonadotropin receptors are rapidly internalized. Biochemistry 38:8703-8712
    • (1999) Biochemistry , vol.38 , pp. 8703-8712
    • Bradbury, F.A.1    Menon, K.M.2
  • 30
    • 0032836647 scopus 로고    scopus 로고
    • A dileucine-based motif in the C-terminal tail of the lutropin/choriogonadotropin receptor inhibits endocytosis of the agonist-receptor complex
    • Nakamura K, Ascoli M 1999 A dileucine-based motif in the C-terminal tail of the lutropin/choriogonadotropin receptor inhibits endocytosis of the agonist-receptor complex. Mol Pharmacol 56:728-736
    • (1999) Mol Pharmacol , vol.56 , pp. 728-736
    • Nakamura, K.1    Ascoli, M.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.