Use of a combined human liver microsome-estrogen receptor binding assay to assess potential estrogen modulating activity of PCB metabolites

Toxicology Letters

Volumn 114, Issue 1-3, 2000, Pages 55-65

  Vakharia, Dilip D ^a   Gierthy, John F ^a  

^a WADSWORTH CENTER   (United States)

Author keywords

Estrogen receptor; HPLC; Human liver microsomes; PCB metabolites

Indexed keywords

2,2',4,4',6,6' HEXACHLOROBIPHENYL; 2,5 DICHLOROBIPHENYL; 2,6,2',6' TETRACHLOROBIPHENYL; 3,4 DICHLOROBIPHENYL; ESTRADIOL; ESTROGEN RECEPTOR; POLYCHLORINATED BIPHENYL; RECOMBINANT RECEPTOR; TRITIUM; UNCLASSIFIED DRUG;

ARTICLE; ASSAY; BINDING COMPETITION; BIOTRANSFORMATION; CHLORINATION; CONTROLLED STUDY; ESTROGEN ACTIVITY; FRACTIONATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN TISSUE; HYDROXYLATION; LIVER MICROSOME; METABOLITE; PRIORITY JOURNAL; RADIOASSAY; RECEPTOR AFFINITY; RECEPTOR BINDING; TECHNIQUE;

ACETATES; BINDING, COMPETITIVE; BIOTRANSFORMATION; CELL-FREE SYSTEM; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR MODULATORS; HUMANS; HYDROXYLATION; MICROSOMES, LIVER; POLYCHLORINATED BIPHENYLS; RECEPTORS, ESTROGEN;

ANIMALIA;

EID: 0034599656     PISSN: 03784274     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0378-4274(99)00194-0     Document Type: Article

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