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Volumn 181-182, Issue , 2002, Pages 275-279

The use of biologically based modeling in risk assessment

Author keywords

Biologically based model; Physiologically based pharmacokinetic; Risk assessment; Uncertainty

Indexed keywords

CARCINOGEN; FORMALDEHYDE;

EID: 0037184865     PISSN: 0300483X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0300-483X(02)00295-0     Document Type: Article
Times cited : (17)

References (16)
  • 1
    • 0035002238 scopus 로고    scopus 로고
    • Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk
    • Bogdanffy M.S., Plowchalk D.R., Sarangapani R., Starr T.B., Andersen M.E. Mode-of-action-based dosimeters for interspecies extrapolation of vinyl acetate inhalation risk. Inhal. Toxicol. 13:2001;377-396.
    • (2001) Inhal. Toxicol. , vol.13 , pp. 377-396
    • Bogdanffy, M.S.1    Plowchalk, D.R.2    Sarangapani, R.3    Starr, T.B.4    Andersen, M.E.5
  • 2
    • 0029069484 scopus 로고
    • A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments
    • Butterworth B.E., Conolly R.B., Morgan K.T. A strategy for establishing mode of action of chemical carcinogens as a guide for approaches to risk assessments. Canc. Lett. 93:1995;129-146.
    • (1995) Canc. Lett. , vol.93 , pp. 129-146
    • Butterworth, B.E.1    Conolly, R.B.2    Morgan, K.T.3
  • 3
    • 77957183484 scopus 로고
    • DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde
    • Casanova M., Morgan K.T., Gross E.A., Moss O.R., Heck H.d'A. DNA-protein cross-links and cell replication at specific sites in the nose of F344 rats exposed subchronically to formaldehyde. Fundam. Appl. Toxicol. 23:1994;525-536.
    • (1994) Fundam. Appl. Toxicol. , vol.23 , pp. 525-536
    • Casanova, M.1    Morgan, K.T.2    Gross, E.A.3    Moss, O.R.4    Heck, H.d'A.5
  • 5
    • 0033670964 scopus 로고    scopus 로고
    • Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA-protein cross-links in F344 rats, rhesus monkeys, and humans
    • Conolly R.B., Lilly P.D., Kimbell J.S. Simulation modeling of the tissue disposition of formaldehyde to predict nasal DNA-protein cross-links in F344 rats, rhesus monkeys, and humans. Environ. Hlth. Perspect. 108:(Suppl. 5):2000;919-924.
    • (2000) Environ. Hlth. Perspect. , vol.108 , Issue.SUPPL. 5 , pp. 919-924
    • Conolly, R.B.1    Lilly, P.D.2    Kimbell, J.S.3
  • 6
    • 0033751510 scopus 로고    scopus 로고
    • The utility of PBPK in the safety assessment of chloroform and carbon tetrachloride
    • Delic J.I., Lilly P.D., MacDonald A.J., Loizou G.D. The utility of PBPK in the safety assessment of chloroform and carbon tetrachloride. Regul. Toxicol. Pharmacol. 32:2000;144-155.
    • (2000) Regul. Toxicol. Pharmacol. , vol.32 , pp. 144-155
    • Delic, J.I.1    Lilly, P.D.2    MacDonald, A.J.3    Loizou, G.D.4
  • 7
    • 0035003225 scopus 로고    scopus 로고
    • A hybrid computational fluid dynamics and physiologically based pharmacokinetic model for comparison of predicted tissue concentrations of acrylic acid and other vapors in the rat and human nasal cavities following inhalation exposure
    • Frederick C.B., Gentry P.R., Bush M.L., Lomax L.G., Black K.A., Finch L., Kimbell J.S., Morgan K.T., Subramaniam R.P., Morris J.B., Ultman J.S. A hybrid computational fluid dynamics and physiologically based pharmacokinetic model for comparison of predicted tissue concentrations of acrylic acid and other vapors in the rat and human nasal cavities following inhalation exposure. Inhal. Toxicol. 13:2001;359-376.
    • (2001) Inhal. Toxicol. , vol.13 , pp. 359-376
    • Frederick, C.B.1    Gentry, P.R.2    Bush, M.L.3    Lomax, L.G.4    Black, K.A.5    Finch, L.6    Kimbell, J.S.7    Morgan, K.T.8    Subramaniam, R.P.9    Morris, J.B.10    Ultman, J.S.11
  • 8
    • 0035121426 scopus 로고    scopus 로고
    • Physiologically based pharmacokinetic modeling of inhalation exposure of humans to dichloromethane during moderate to heavy exercise
    • Jonsson F., Bois F., Johanson G. Physiologically based pharmacokinetic modeling of inhalation exposure of humans to dichloromethane during moderate to heavy exercise. Toxicol. Sci. 59:2001;209-218.
    • (2001) Toxicol. Sci. , vol.59 , pp. 209-218
    • Jonsson, F.1    Bois, F.2    Johanson, G.3
  • 9
    • 0027313660 scopus 로고
    • Application of computational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat
    • Kimbell J.S., Gross E.A., Joyner D.R., Godo M.N., Morgan K.T. Application of computational fluid dynamics to regional dosimetry of inhaled chemicals in the upper respiratory tract of the rat. Toxicol. Appl. Pharmacol. 121:1993;253-263.
    • (1993) Toxicol. Appl. Pharmacol. , vol.121 , pp. 253-263
    • Kimbell, J.S.1    Gross, E.A.2    Joyner, D.R.3    Godo, M.N.4    Morgan, K.T.5
  • 10
    • 0035172387 scopus 로고    scopus 로고
    • Dosimetry modeling of inhaled formaldehyde: Comparisons of local flux predictions in the rat, monkey, and human nasal passages
    • Kimbell, J.S., Subramaniam, R.P., Gross, E.A., Schlosser, P.M. Morgan, K.T., 2001a. Dosimetry modeling of inhaled formaldehyde: Comparisons of local flux predictions in the rat, monkey, and human nasal passages, Inhalation Toxicol. Sci. 64, 100-110.
    • (2001) Inhalation Toxicol. Sci. , vol.64 , pp. 100-110
    • Kimbell, J.S.1    Subramaniam, R.P.2    Gross, E.A.3    Schlosser, P.M.4    Morgan, K.T.5
  • 14
    • 0035158879 scopus 로고    scopus 로고
    • Dosimetry modeling of inhaled formaldehyde in the respiratory tract: The human lung
    • Overton, J.H., Kimbell, J.S., Miller, F.J., 2001. Dosimetry modeling of inhaled formaldehyde in the respiratory tract: the human lung. Inhalation Toxicol. Sci. 64, 122-134.
    • (2001) Inhalation Toxicol. Sci. , vol.64 , pp. 122-134
    • Overton, J.H.1    Kimbell, J.S.2    Miller, F.J.3
  • 15
  • 16
    • 0003427744 scopus 로고
    • Office of Toxic Substances, Washington, DC
    • US Environmental Protection Agency (US EPA) 1991. Formaldehyde Risk Assessment Update - Final Draft. Office of Toxic Substances, Washington, DC.
    • (1991) Formaldehyde Risk Assessment Update - Final Draft


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.