Inflammation, genetics, and ischemic heart disease: Focus on the major histocompatibility complex (MHC) genes

Cytokine

Volumn 29, Issue 5, 2005, Pages 187-196

  Porto, Italo ^a,b   Leone, Antonio Maria ^a   Crea, Filippo ^a   Andreotti, Felicita ^a  

^a CATHOLIC UNIVERSITY   (Italy)

^b JOHN RADCLIFFE HOSPITAL   (United Kingdom)

Author keywords

Atherosclerosis; Immunity; MHC; Myocardial infarction; Polymorphisms

Indexed keywords

COMPLEMENT COMPONENT C4; COMPLEMENT COMPONENT C4A; COMPLEMENT COMPONENT C4B; HEAT SHOCK PROTEIN 70; HEAT SHOCK PROTEIN 70 1; HFE PROTEIN; HLA DR ANTIGEN; IRON; LEUKOCYTE ANTIGEN; LYMPHOTOXIN; MAJOR HISTOCOMPATIBILITY ANTIGEN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 2; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 3; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ALLELE; AUTOIMMUNE DISEASE; CARDIOVASCULAR RISK; CHROMOSOME 6; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY DISEASE; DISEASE MODEL; GENE LINKAGE DISEQUILIBRIUM; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC RISK; GENETIC VARIABILITY; GENOME ANALYSIS; GERMANY; HAPLOTYPE; HEART INFARCTION; HEMOCHROMATOSIS; HUMAN; IMMUNE RESPONSE GENE; IMMUNOGENETICS; INFLAMMATION; INFLAMMATORY DISEASE; ISCHEMIC HEART DISEASE; JAPAN; LINKAGE ANALYSIS; MAJOR HISTOCOMPATIBILITY COMPLEX; METHODOLOGY; NULL ALLELE; PATHOGENESIS; POLYMORPHIC LOCUS; POPULATION GENETICS; PRIORITY JOURNAL; RACE DIFFERENCE; REVIEW; RHEUMATOID ARTHRITIS;

EID: 14744271419     PISSN: 10434666     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cyto.2004.09.010     Document Type: Article

References (56)

1. R. Ross Atherosclerosis - an inflammatory disease N Engl J Med 340 1999 115 126
2. G. Wick, H. Perschinka, and Q. Xu Autoimmunity and atherosclerosis Am Heart J 138 1999 S444 S449
3. V. Pasceri, and E.T. Yeh A tale of two diseases: atherosclerosis and rheumatoid arthritis Circulation 100 1999 2124 2126
4. G. Caligiuri, G. Paulsson, A. Nicoletti, A. Maseri, and G. Hansson Evidence for antigen-driven T-cell response in unstable angina Circulation 102 2000 1114 1119
5. E. Thorsby Invited anniversary review: HLA associated diseases Hum Immunol 53 1997 1 11
6. J.R. Gruen, and S.M. Weissman Evolving view of the major histocompatibility complex Blood 90 1997 4252 4265
7. F. Andreotti, I. Porto, F. Crea, and A. Maseri Inflammatory gene polymorphisms and ischemic heart disease: review of population association studies Heart 87 2002 107 112
8. N.J. Makhatadze Tumor necrosis factor locus: genetic organisation and biological implications Hum Immunol 59 1998 571 579
9. A.H. Hajeer, and I.V. Hutchinson Influence of TNFα gene polymorphisms on TNFα production and disease Hum Immunol 62 2001 1191 1199
10. P. Barath, M.C. Fishbein, J. Cao, J. Berenson, R.H. Helfant, and J.S. Forrester Detection and localisation of tumor necrosis factor in human atheroma Am J Cardiol 65 1990 297 302
11. K. Vaddi, F.A. Nicolini, P. Mehta, and J.L. Mehta Increased secretion of tumor necrosis factor-alfa and interferon-gamma by mononuclear leukocytes in patients with ischemic heart disease Circulation 90 1994 694 699
12. G.S. Hotamisligil, and B.M. Spiegelman Tumor necrosis factor alfa. A key component of the obesity-diabetes link Diabetes 3 1994 1271 1278
13. M. Toborek, E.M. Blanc, S. Kaiser, M.P. Mattson, and B. Henning Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells J Lipidol Res 38 1997 2155 2167
14. R.A. Allen, E.M. Lee, D.H. Roberts, B.K. Park, and M. Pirmohamed Polymorphisms in the TNF-α and TNF-receptor genes in patients with coronary artery disease Eur J Clin Invest 31 2001 843 851
15. H. Elghannam, S. Tavackoli, L. Ferlic, A.M. Gotto Jr., C.M. Ballantyne, and A.J. Marian A prospective study of genetic markers of susceptibility to infection and inflammation, and the severity, progression, and regression of coronary atherosclerosis and its response to therapy J Mol Med 78 2000 562 568
16. S.M. Herrmann, S. Ricard, V. Nicaud, C. Mallet, D. Arveiler, and A. Evans Polymorphisms of the tumour necrosis factor-alpha gene, coronary heart disease and obesity Eur J Clin Invest 28 1998 59 66
17. W. Koch, A. Kastrati, C. Bottiger, J. Mehilli, N. von Beckerath, and A. Schomig Interleukin-10 and tumor necrosis factor gene polymorphisms and risk of coronary artery disease and myocardial infarction Atherosclerosis 159 2001 137 144
18. C. Szalai, G. Fust, J. Duba, J. Kramer, L. Romics, and Z. Prohaszka Association of polymorphisms and allelic combinations in the tumour necrosis factor-alfa-complement MHC regions with coronary artery disease J Med Genet 39 2002 46 51
19. K. Ozaki, Y. Ohnishi, A. Iida, A. Sekine, R. Yamada, and T. Tsunoda Functional SNPs in the lymphotoxin-alpha gene that are associated with susceptibility to myocardial infarction Nat Genet 32 2002 650 654
20. A. Iida, K. Ozaki, Y. Ohnishi, T. Tanaka, and Y. Nakamura Identification of 46 novel SNPs in the 130-kb region containing a myocardial infarction susceptibility gene on chromosomal band 6p21 J Hum Genet 48 2003 476 479
21. J. Klein, and A. Sato The HLA system. First of two parts N Engl J Med 343 2000 702 709
22. S. Stemme, G. Fager, and G.K. Hansson MHC class II antigen expression in human vascular smooth muscle cells is induced by interferon-gamma and modulated by tumor necrosis factor and lymphotoxin Immunology 69 1990 243 249
23. A. van der Waal, A.E. Becker, C.H. van der Loos, and P.K. Das Site of intimal rupture or erosion of thrombosed coronary atherosclerotic plaques is characterized by an inflammatory process irrespective of the dominant plaque morphology Circulation 89 1994 36 44
24. G.H. Dahlén, J. Boman, L. Slunga, and B. Lindblom Lp(a) lipoprotein, IgG, IgA and IgM antibodies to Chlamydia pneumoniae and HLA class II genotype in early coronary artery disease Atherosclerosis 114 1995 165 174
25. L. Jonasson, T. Eriksson, G.H. Dahlén, and B. Lindblom Lipoprotein(a) and HLA-DRB1 and DQB1 genes in coronary artery disease Atherosclerosis 133 1997 111 114
26. G. Sperti, C. Varlotta, and I. Porto Lower prevalence of specific allele at the DRB1 MHC class II locus (DR2) in young myocardial infarction patients compared to older subjects J Am Coll Cardiol 35 Suppl. 2000 394 [abstract]
27. I.J. Benjamin, and D.R. McMillan Stress (heat shock) proteins: molecular chaperones in cardiovascular biology and disease Circ Res 83 1998 117 132
28. M.K. Bolla, G.J. Miller, D.M. Yellon, A. Evans, G. Luc, and J.P. Cambou Analysis of the association of a heat shock protein 70-1 gene promoter polymorphism with myocardial infarction and coronary risk traits Dis Markers 13 4 1998 227 235
29. J.N. Feder, A. Gnirke, W. Thomas, Z. Tsuchihashi, D.A. Ruddy, and A. Basava A novel MHC class-I like gene is mutated in patients with hereditary haemochromatosis Nat Genet 13 1996 399 408
30. Z.J. Bulaj, L.M. Griffen, L.B. Jorde, C.Q. Edwards, and J.P. Kushner Clinical and biochemical abnormalities in people heterozygous for hemochromatosis N Engl J Med 335 1996 1799 1805
31. J.L. Sullivan, and L.R. Zacharski Hereditary haemochromatosis and the hypothesis that iron depletion protects against ischemic heart disease Eur J Clin Invest 31 2001 375 377
32. A. Ascherio, E.B. Rimm, E. Giovannucci, W.C. Willett, and M.J. Stampfer Blood donations and the risk of coronary heart disease in men Circulation 103 2001 52 57
33. B.A. Nassar, E.M. Zayed, L.M. Title, B.J. O'Neill, I.R. Bata, and S.A. Kirkland Relation of HFE gene mutations, high iron stores and early onset coronary disease Can J Cardiol 14 1998 215 220
34. R.F. Franco, M.A. Zago, M.D. Trip, H. ten Cate, A. van den Ende, and M.H. Prins Prevalence of hereditary hemochromatosis in premature atherosclerotic vascular disease Br J Haematol 102 1998 1172 1175
35. M. Roest, Y.T. van der Schouw, B. de Valk, J.J. Marx, M.J. Tempelman, and P.G. de Groot Heterozygosity for a hereditary hemochromatosis is associated with cardiovascular death in women Circulation 100 1999 1268 1273
36. T.P. Tuomainen, K. Kontula, K. Nyyssonen, T.A. Lakka, T. Helio, and J.T. Salonen Increased risk of acute myocardial infarction in carriers of the hemochromatosis gene Cys282Tyr mutation: a prospective cohort study in men in eastern Finland Circulation 100 1999 1274 1279
37. J.M. Annichino-Bizzacchi, S.T. Saad, V.R. Arruda, J.A. Ramires, L.H. Siqueira, and L.C. Chiaparini C282Y mutation in the HLA-H gene is not a risk factor for patients with myocardial infarction J Cardiovasc Risk 7 2000 37 40
38. R.T. Calado, R.F. Franco, A. Pazin-Filho, M.V. Simoes, J.A. Marin-Neto, and M.A. Zago HFE gene mutations in coronary atherothrombotic disease Braz J Med Biol Res 33 2000 301 306
39. E. Battiloro, D. Ombres, E. Pascale, E. D'Ambrosio, R. Verna, and M. Arca Haemochromatosis gene mutations and risk of coronary artery disease Eur J Hum Genet 8 2000 389 392
40. M. Margaglione, A. Di Castelnuovo, A. Totaro, L. Iacoviello, and G. Di Minno Risk of myocardial infarction in carriers of mutations in the hemochromatosis-associated gene Thromb Haemost 84 2000 726 727
41. E. Rossi, B.M. Mcquillan, J. Hung, P.L. Thompson, C. Kuek, and J.P. Beilby Serum ferritin and C282Y mutation of the hemochromatosis gene as predictors of asymptomatic carotid atherosclerosis in a community population Stroke 31 2000 3015
42. M.L. Rasmussen, A.R. Folsom, D.J. Catellier, M.Y. Tsai, U. Garg, and J.H. Eckfeldt A prospective study of coronary heart disease and the hemochromatosis gene (HFE) C282Y mutation: the Atherosclerosis Risk in Communities (ARIC) study Atherosclerosis 154 2001 739 746
43. G. Hetet, A. Elbaz, J. Gariepy, V. Nicaud, and D. Arveiler Association studies between hemochromatosis gene mutations and the risk of cardiovascular diseases Eur J Clin Invest 31 2001 382 388
44. A.C. Pereira, M.A.R. Cuoco, and G.F. Mota Hemochromatosis gene variants in ischemic cardiomyopathy Am J Cardiol 88 2001 388 391
45. C. Bozzini, D. Girelli, E. Tinazzi, O. Olivieri, C. Stranieri, and A. Bassi Biochemical and genetic markers of iron status and the risk of coroary artery disease: an angiography-based study Clin Chem 48 2002 622 628
46. D. Claeys, M. Walting, F. Julmy, W.A. Wuillemin, and B.J. Meyer Hemochromatosis mutations and ferritin in myocardial infarction: a case-control study Eur J Clin Invest 32 Suppl. I 2002 3 8
47. R. Surber, H.H. Sigusch, H. Kuehnert, and H.R. Figulla Haemochromatosis (HFE) gene C282Y mutation and the risk of coronary artery disease and myocardial infarction: a study in 1279 patients undergoing coronary angiography J Med Genet 40 2003 e58
48. J.A. Shifferli, Y.C. Ng, and D.K. Peters The role of complement and its receptors in the elimination of the immune complexes N Engl J Med 315 1984 488 495
49. G. Hauptmann Inherited deficiency of the fourth component of human complement Immunol Rev 1 1988 3 22
50. N.A. Bishof, T.R. Welch, and L.S. Beischel C4B deficiency: a risk factor for bacteremia with encapsulated organisms J Infect Dis 162 1990 248 250
51. J. Torzewski, D.E. Bowyer, J. Waltenberger, and C. Fitzsimmons Processes in atherogenesis: complement activation Atherosclerosis 132 1997 131 138
52. D.D. Gladmann, and M.B. Urowitz Morbidity in systemic lupus erythematosus J Reumathol 13 1987 223 226
53. J. Kramer, T. Fulop, K. Rajczy, A.T. Nguyen, and G. Fust A marked drop in the incidence of the null allele of the B gene of the fourth component of the complement (C4B*Q0) in elderly subjects: C4B*Q0 as a probably negative selection factor for survival Hum Genet 86 1991 595 598
54. J. Kramer, K. Rajczy, L. Hegyi, T. Fulop, A. Mohacsi, and Z. Mezei C4B*Q0 allotype as risk factor for myocardial infarction BMJ 309 1994 313 314
55. A.K. Lefvert, A. Hamsten, and G. Holm Association between circulating immune complexes, complement C4 null alleles and myocardial infarction before age 45 years Arterioscler Thromb Vasc Biol 15 1995 665 668
56. S. Nityanand, A. Hamsten, H. Lithell, G. Holm, and A.K. Lefvert C4 null alleles and myocardial infarction Atherosclerosis 143 1999 377 381