Linoleic acid potentiates TNF-mediated oxidative stress, disruption of calcium homeostasis, and apoptosis of cultured vascular endothelial cells

Journal of Lipid Research

Volumn 38, Issue 10, 1997, Pages 2155-2167

  Toborek, Michal ^a   Blanc, Emmanuelle M ^a   Kaiser, Simone ^a,b   Mattson, Mark P ^a   Hennig, Bernhard ^b  

^a UNIVERSITY OF POTSDAM   (Germany)

^b UNIVERSITY OF KENTUCKY   (United States)

Author keywords

Antioxidants; Apoptosis; Atherosclerosis; Cytokines; Fatty acids; Intracellular calcium; Oxidative stress

Indexed keywords

ALPHA TOCOPHEROL; AURINTRICARBOXYLIC ACID; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GALLIC ACID PROPYL ESTER; LINOLEIC ACID; TUMOR NECROSIS FACTOR;

ANIMAL CELL; APOPTOSIS; ARTICLE; CALCIUM CELL LEVEL; CALCIUM HOMEOSTASIS; CELL PROTECTION; CONTROLLED STUDY; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SWINE; VASCULAR ENDOTHELIUM;

EID: 0030667571     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (56)

1. Zilversmit, D. B. 1973. A proposal linking atherogenesis to the interaction of endothelial lipoprotein lipase with triglyceride-rich lipoproteins. Circ. Res. 33: 633-638.
2. Hennig, B., M. Toborek, C. J. McClain, and J. N. Diana. 1996. Nutritional implications in vascular endothelial cell metabolism. J. Am. Coll. Nutr. 15: 345-358.
3. Toborek, M., S. W. Barger, M. P. Mattson, S. Barve, C. J. McClain, and B. Hennig. 1996. Linoleic acid and TNF-α cross-amplify oxidative injury and dysfunction of endothelial cells. J. Lipid Res. 37: 123-135.
4. Davda, R. K., K. T. Stepniakowski, G. Lu, M. E. Ullian, T. L. Goodfriend, and B. M. Egan. 1995. Oleic acid inhibits endothelial nitric oxide synthase by a protein kinase C-independent mechanism. Hypertension. 26: 764-770.
5. Toborek, M., and B. Hennig. 1993. Vitamin E attenuates induction of elastase-like activity by tumor necrosis factor-α, cholestan-3β,5α,6β-triol, and linoleic acid in cultured endothelial cells. Clin. Chim. Acta. 215: 201-211.
6. Ramasamy, S., G. A. Boissonneault, D. W. Lipke, and B. Hennig. 1993. Proteoglycans and endothelial barrier function: effect of linoleic acid exposure to porcine pulmonary artery endothelial cells. Atherosclerosis. 103: 279-290.
7. de Haan, L. H., I. Bosselaers, W. M. Jongen, R. M. Zwijsen, and J. Koeman. 1994. Effect of lipids and aldehydes on gap-junctional intercellular communication between human smooth muscle cells. Carcinogenesis. 15: 253-256.
8. Reid, V. C., S. J. Hardwick, and M. J. Mitchinson. 1993. Fragmentation of DNA in P388D1 macrophages exposed to oxidised low-density lipoprotein. FEBS Lett. 332: 218-220.
9. Sweetman, L. L., N. Y. Zhang, H. Peterson, R. Gopalakrishna, and A. Sevanian. 1995. Effect of linoleic acid hydroperoxide on endothelial cell calcium homeostasis and phospholipid hydrolysis. Arch. Biochem. Biophys. 323: 97-107.
10. Hennig, B., C. Enoch, and C. K. Chow. 1987. Protection by vitamin E against endothelial cell injury by linoleic acid hydroperoxides. Nutr. Res. 7: 1253-1260.
11. Sandstrom, P. A., D. Pardi, P. W. Tebbey, R. W. Dudek, D. M. Terrian. T. M. Folks, and T. M. Buttke. 1995. Lipid hydroperoxide-induced apoptosis: lack of inhibition by Bcl-2 over-expression. FEBS Lett. 365: 66-70.
12. Folcik, V. A., and M. K. Cathcart. 1994. Predominance of esterified hydroperoxy-linoleic acid in human monocyte-oxidized LDL. J. Lipid Res. 35: 1570-1582.
13. Bjorkerud, B., and S. Bjorkerud. 1996. Contrary effects of lightly and strongly oxidized LDL with potent promotion of growth versus apoptosis on arterial smooth muscle cells, macrophages, and fibroblasts. Arterioscler. Thromb. Vasc. Biol. 16: 416-424.
14. de Bono, D. P., and W. D. Yang. 1995. Exposure to low concentrations of hydrogen peroxide causes delayed endothelial cell death and inhibits proliferation of surviving cells. Atherosclerosis. 114: 235-245.
15. Tracey, K. J., and A. Cerami. 1992. Tumor necrosis factor and regulation of metabolism in infection: role of systemic versus tissue levels. Proc. Soc. Exp. Biol. Med. 200: 233-239.
16. Vaddi, K., F. A. Nicolini, P. Mehta, and J. L. Mehta. 1994. Increased secretion of tumor necrosis factor-α and interferon-γ by mononuclear leukocytes in patients with ischemic heart disease. Relevance in superoxide anion generation. Circulation. 90: 694-699.
17. Rus, H. G., F. Niculescu, and R. Vlaicu. 1991. Tumor necrosis factor-alpha in human arterial wall with atherosclerosis. Atherosclerosis. 89: 247-254.
18. Barath, P., M. C. Fishbein, J. Cao, J. Berenson, R. H. Helfant, and J. S. Forrester. 1990. Detection and localization of tumor necrosis factor in human atheroma. Am. J. Cardiol. 65: 297-302.
19. Read, M. A., A. S. Neish, F. W. Luscinskas, V. J. Palombella, T. Maniatis, and T. Collins. 1995. The proteasome pathway is required for cytokine-induced endothelial-leukocyte adhesion molecule expression. Immunity. 2: 493-506.
20. Collins, T., M. A. Read, A. S. Neish, M. Z. Whitley, D. Thanos, and T. Maniatis. 1995. Transcriptional regulation of endothelial cell adhesion molecules: NF-κB and cytokine-inducible enhancers. FASEB J. 9: 899-909.
21. Pulunovsky, V. A., C. H. Wendt, D. H. Ingbar, M. S. Peterson, and P. B. Bitterman. 1994. Induction of endothelial cell apoptosis by TNF alpha: modulation by inhibitors of protein synthesis. Exp. Cell Res. 214: 584-594.
22. Khan, B. V., S. S. Parthasarathy, R. W. Alexander, and R. M. Medford. 1995. Modified low density lipoprotein and its constituents augment cytokine-activated vascular cell adhesion molecule-1 gene expression in human vascular endothelial cells. J. Clin. Invest. 95: 1262-1270.
23. Maziere, C., M. Auclair, and J. C. Maziere. 1994. Tumor necrosis factor enhances low density lipoprotein oxidative modification by monocytes and endothelial cells. FEBS Lett. 338: 43-46.
24. Hayakawa, M., N. Ishida, K. Takeuchi, S. Shibamoto, T. Hori, N. Oku, F. Ito, and M. J. Tsujimoto. 1993. Arachidonic acid-selective cytosolic phospholipase A2 is crucial in the cytotoxic action of tumor necrosis factor. J. Biol. Chem. 268: 11290-11295.
25. Camacho, M., N. Godessart, R. Anton, M. Garcia, and L. Vila. 1995. Interleukin-1 enhances the ability of cultured human umbilical vein endothelial cells to oxidize linoleic acid. J. Biol. Chem. 270: 17279-17286.
26. Renier, G., E. Skamene, J. B. DeSanctis, and D. Radzioch. 1994. Induction of tumor necrosis factor α gene expression by lipoprotein lipase. J. Lipid Res. 35: 271-278.
27. Reiner, G., M. Olivier, E. Skamene, and D. Radzioch. 1994. Induction of tumor necrosis factor alpha gene expression by lipoprotein lipase requires protein kinase C activation. J. Lipid Res. 35: 1413-1421.
28. Hennig, B., D. M. Shasby, A. B. Fulton, and A. A. Spector. 1984. Exposure to free fatty acid increases the transfer of albumin across cultured endothelial monolayers. Arteriosclerosis. 4: 489-497.
29. Toborek, M., S. W. Barger, M. P. Mattson, C. J. McClain, and B. Hennig. 1995. Role of glutathione redox cycle in TNF-mediated endothelial cell dysfunction. Atherosclerosis. 117: 179-188.
30. Toborek, M., and B. Hennig. 1994. Fatty acid-mediated effects on the glutathione redox cycle in cultured endothelial cells. Am. J. Clin. Nutr: 59: 60-65.
31. Mattson, M. P., S. W. Barger, J. G. Begley, and R. J. Mark. 1995. Calcium, free radicals, and excitotoxic neuronal death in primary cell culture. Methods Cell Biol. 46: 187-215.
32. 2 in cultured endothelial cells. Arch. Biochem. Biophys. 302: 348-355.
33. Grynkiewicz, G., M. Poenie, and R. Y. Tsien. 1985. A new generation of calcium indicators with greatly improved fluorescence properties. J. Biol. Chem. 260: 3440-3450.
34. Blanc, E. M., M. Toborek, R. J. Mark, B. Hennig, and M. P. Mattson. 1997. Amyloid β-peptide (25-35) induces cell monolayer albumin permeability, impairs glucose transport, and induces apoptosis in vascular endothelial cells. J. Neurochem. 68: 1870-1881.
35. Reid, S., R. Cross, and E. C. Snow. 1996. Combined Hoechst 33342 and merocyanine 540 staining to examine murine B cell cycle stage, viability, and apoptosis J. Immunol. Methods. 192: 43-54.
36. Chiu, L., H. Cherwinski, J. Ransom, and J. F. Dunne. 1996. Flow cytometric ratio analysis of the Hoechst 33342 emission spectrum: multiparametric characterization of apoptotic lymphocytes. J. Immunol. Methods. 189: 157-171.
37. Hennig, B., M. Toborek, S. Joshi-Barve, S. W. Barger, S. Barve, M. P. Mattson, and C. J. McClain. 1996. Linoleic acid activates NF-κB and induces NF-κB-dependent transcription in cultured endothelial cells. Am. J. Clin. Nutr. 63: 322-328.
38. Mattson, M. P., and S. W. Scheff. 1994. Endogenous neuroprotection factors and traumatic brain injury: mechanisms of action and implications for therapy. J. Neurotrauma. 11: 3-33.
39. Bjorkerud, S., and B. Bjorkerud. 1996. Apoptosis is abundant in human atherosclerotic lesions, especially in inflammatory cells (macrophages and T cells), and may contribute to the accumulation of gruel and plaque instability. Am. J. Pathol. 149: 367-380.
40. Geng, Y. J., and P. Libby. 1995. Evidence for apoptosis in advanced human atheroma. Colocalization with interleukin-1 beta-converting enzyme. Am. J. Pathol 147: 251-266.
41. Han, D. K., C. C. Haudenschild, M. K. Hong, B. T. Tinkle, M. B. Leon, and G. Liau. 1995. Evidence for apoptosis in human atherogenesis and in a rat vascular injury model. Am. J. Pathol. 147: 267-277.
42. Bochaton-Piallat, M. L., F. Gabbiani, M. Redard, A. Desmouliere, and G. Gabbiani. 1995. Apoptosis participates in cellularity regulation during rat aortic intimal thickening. Am. J. Pathol. 146: 1059-1064.
43. Kockx, M. M., G. R. De Meyer, J. Muhring, H. Bult. J. Bultinck, and A. G. Herman. 1996. Distribution of cell replication and apoptosis in atherosclerotic plaques of cholesterol-fed rabbits. Atherosclerosis. 120: 115-124.
44. Geng, Y. J., Q. Wu, M. Muszynski, G. K. Hansson, and P. Libby. 1996. Apoptosis of vascular smooth muscle cells induced by in vitro stimulation with interferon-gamma, tumor necrosis factor-alpha, and interleukin-1 beta. Arterioscler. Thromb. Vasc. Biol. 16: 19-27.
45. Yang, J. J., R. Kettritz, R. J. Falk, J. C. Jennette, and M. L. Gaido. 1996. Apoptosis of endothelial cells induced by the neutrophil serine proteases proteinase 3 and elastase. Am. J. Pathol. 149: 1617-1626.
46. Mark, R. J., M. A. Lovell, W. R. Markesbery, K. Uchida, and M. P. Mattson. 1997. A role of 4-hydroxynonenal, an aldehydic product of lipid peroxidation, in disruption of ion homeostatis and neuronal death induced by amyloid β-peptide. J. Neurochim. 68: 255-264.
47. Ramasamy, S., G. A. Boissonneault, E. A. Decker, and B. Hennig. 1991. Linoleic acid-induced endothelial cell injury: role of membrane-bound enzyme activities and lipid oxidation. J. Biochem. Toxicol. 6: 29-35.
48. Slowik, M. R., L. G. De Luca, W. Min, and J. S. Pober. 1996. Ceramide is not a signal for tumor necrosis factor-induced gene expression but does cause programmed cell death in human vascular endothelial cells. Circ. Res. 79: 736-747.
49. Modur, V., G. A. Zimmerman, S. M. Prescott, and T. M. McIntyre. 1996. Endothelial cell inflammatory responses to tumor necrosis factor β. Ceramide-dependent and -independent mitogen-activated protein kinase cascades. J. Biol. Chem. 271: 13094-13102.
50. Packham, G., and J. L. Cleveland. 1995. c-Myc and apoptosis. Biochim. Biophys. Acta. 1242: 11-28.
51. Heerdt, B. G., M. A. Houston, and L. H. Augenlicht. 1994. Potentiation by specific short-chain fatty acids of differentiation and apoptosis in human colonic carcinoma cell lines. Cancer Res. 54: 3288-3293.
52. Slater, A. F., C. S. Nobel, and S. Orrenius. 1995. The role of intracellular oxidants in apoptosis. Biochim. Biophys. Acta. 1271: 59-62.
53. Beaver, J. P., and P. Waring. 1995. A decrease in intracellular glutathione concentration precedes the onset of apoptosis in marine thymocytes. Eur. J. Cell Biol. 68: 47-54.
54. Sato, N., S. Iwata, K. Nakamura, T. Hori, K. Mori, and J. Yodoi. 1995. Thiol-mediated redox regulation of apoptosis. Possible roles of cellular thiols other than glutathione in T cell apoptosis. J. Immunol. 154: 3194-3203.
55. McConkey, D. J., and S. Orrenius. 1996. The role of calcium in the regulation of apoptosis. J. Leukocyte Biol. 59: 775-783.
56. Siflinger-Birnboim, A., J. Schnitzer, H. Lum, F. A. Blumenstock, C-P. J. Shen, P. J. Del Vecchio, and A. E. Malik. 1991. Lectin binding to gp60 decreases specific albumin binding and transport in pulmonary artery endothelial monolayers. J. Cell Physiol. 149: 575-584.