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Volumn 144, Issue 3, 2005, Pages 394-399

The soy isoflavone genistein induces a late but sustained activation of the endothelial nitric oxide-synthase system in vitro

Author keywords

Endothelial nitric oxide synthase; Isoflavones; Nitric oxide; Phytoestrogens; Soy

Indexed keywords

ARGININE; BIOCHANIN A; CITRULLINE; DAIDZEIN; ENDOTHELIAL NITRIC OXIDE SYNTHASE; FLUORESCENT DYE; FORMONONETIN; GENISTEIN; ISOFLAVONE; NITRIC OXIDE; PHYTOESTROGEN;

EID: 14644435162     PISSN: 00071188     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.bjp.0706075     Document Type: Article
Times cited : (53)

References (32)
  • 1
    • 0026075305 scopus 로고
    • Use and specificity of genistein as inhibitor of protein-thyrosine kinases
    • AKIYAMA, T. & OGAWARA, H. (1991). Use and specificity of genistein as inhibitor of protein-thyrosine kinases. Methods Enzymol, 201, 362-370.
    • (1991) Methods Enzymol , vol.201 , pp. 362-370
    • Akiyama, T.1    Ogawara, H.2
  • 2
    • 0035677762 scopus 로고    scopus 로고
    • Endothelium in vitro: A review of human vascular endothelial cell lines for blood vessel-related research
    • BOUIS, D., HOSPERS, G.A.P., MEIJER, C., MOLEMA, G. & MULDER, N.H. (2001). Endothelium in vitro: a review of human vascular endothelial cell lines for blood vessel-related research. Angiogenesis, 4, 91-102.
    • (2001) Angiogenesis , vol.4 , pp. 91-102
    • Bouis, D.1    Hospers, G.A.P.2    Meijer, C.3    Molema, G.4    Mulder, N.H.5
  • 4
    • 0036195172 scopus 로고    scopus 로고
    • Soy, soy phytoestrogens and cardiovascular disease
    • CLARKSON, T.B. (2002). Soy, soy phytoestrogens and cardiovascular disease. J. Nutr., 132, 566S-569S.
    • (2002) J. Nutr. , vol.132
    • Clarkson, T.B.1
  • 5
    • 0041522774 scopus 로고    scopus 로고
    • Isolated soy protein improves endothelial function in postmenopausal hypercholesterolemic women
    • CUEVAS, A.M., IRRIBARRA, V.L., CASTILLO, O.A., YANEZ, M.D. & GERMAIN, A.M. (2003). Isolated soy protein improves endothelial function in postmenopausal hypercholesterolemic women. Eur. J. Clin. Nutr., 57, 889-894.
    • (2003) Eur. J. Clin. Nutr. , vol.57 , pp. 889-894
    • Cuevas, A.M.1    Irribarra, V.L.2    Castillo, O.A.3    Yanez, M.D.4    Germain, A.M.5
  • 6
    • 0037377576 scopus 로고    scopus 로고
    • Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training
    • DAVIS, M.E., CAI, H., MCCANN, L., FUKAI, T. & HARRISON, D.G. (2003). Role of c-Src in regulation of endothelial nitric oxide synthase expression during exercise training. Am. J. Physiol. Heart Circ. Physiol., 284, H1449-H1453.
    • (2003) Am. J. Physiol. Heart Circ. Physiol. , vol.284
    • Davis, M.E.1    Cai, H.2    Mccann, L.3    Fukai, T.4    Harrison, D.G.5
  • 7
    • 0001637870 scopus 로고
    • Permanent cell line expressing human factor VIII-related antigen established by hybridisation
    • EDGELL, C.J.S., MC DONALD, C.C. & GRAHAM, J.B. (1983). Permanent cell line expressing human factor VIII-related antigen established by hybridisation. Proc. Natl. Acad. Sci. U.S.A., 80, 3734-3737.
    • (1983) Proc. Natl. Acad. Sci. U.S.A. , vol.80 , pp. 3734-3737
    • Edgell, C.J.S.1    Mc Donald, C.C.2    Graham, J.B.3
  • 8
    • 0037422527 scopus 로고    scopus 로고
    • Truncated estrogen receptor α 46-kDa isoform in human endothelial cells. Relationship to acute activation of nitric oxide synthase
    • FIGTREE, G.A., MC DONALD, D., WATKINS, H. & CHANNON, K.M. (2003). Truncated estrogen receptor α 46-kDa isoform in human endothelial cells. Relationship to acute activation of nitric oxide synthase. Circulation, 107, 120-126.
    • (2003) Circulation , vol.107 , pp. 120-126
    • Figtree, G.A.1    Mc Donald, D.2    Watkins, H.3    Channon, K.M.4
  • 9
    • 0037216768 scopus 로고    scopus 로고
    • Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase
    • FLEMMING, I. & BUSSE, R. (2003). Molecular mechanisms involved in the regulation of the endothelial nitric oxide synthase. Am. J. Physiol. Regul. Integr. Comp. Physiol., 284, R1-R12.
    • (2003) Am. J. Physiol. Regul. Integr. Comp. Physiol. , vol.284
    • Flemming, I.1    Busse, R.2
  • 10
    • 0037462671 scopus 로고    scopus 로고
    • Src kinase mediates phophatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen
    • HAYNES, M.P., LI, L., SINHA, D., RUSSELL, K.S., HISAMOTO, K., BARON, R., COLLINGE, M., SESSA, W. & BENDER, J.R. (2003). Src kinase mediates phophatidylinositol 3-kinase/Akt-dependent rapid endothelial nitric-oxide synthase activation by estrogen. J. Biol. Chem., 278, 2118-2123.
    • (2003) J. Biol. Chem. , vol.278 , pp. 2118-2123
    • Haynes, M.P.1    Li, L.2    Sinha, D.3    Russell, K.S.4    Hisamoto, K.5    Baron, R.6    Collinge, M.7    Sessa, W.8    Bender, J.R.9
  • 11
    • 0031033526 scopus 로고    scopus 로고
    • Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques
    • HONORE, E.K., WILLIAMS, J.K., ANTHONY, M.S. & CLARKSON, T.B. (1997). Soy isoflavones enhance coronary vascular reactivity in atherosclerotic female macaques. Fertil. Steril., 67, 148-154.
    • (1997) Fertil. Steril. , vol.67 , pp. 148-154
    • Honore, E.K.1    Williams, J.K.2    Anthony, M.S.3    Clarkson, T.B.4
  • 12
    • 0037448074 scopus 로고    scopus 로고
    • The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: An antioxidant mechanism for cell-mediated LDL modification
    • HWANG, J., WANG, J., MORAZZONI, P., HODIS, H.N. & SEVANIAN, A. (2003). The phytoestrogen equol increases nitric oxide availability by inhibiting superoxide production: an antioxidant mechanism for cell-mediated LDL modification. Free Radic. Biol. Med., 34, 1271-1282.
    • (2003) Free Radic. Biol. Med. , vol.34 , pp. 1271-1282
    • Hwang, J.1    Wang, J.2    Morazzoni, P.3    Hodis, H.N.4    Sevanian, A.5
  • 13
    • 0042072989 scopus 로고    scopus 로고
    • Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein E-deficient mice
    • JIANG, F., JONES, G.T., HUSBAND, A.J. & DUSTING, G.J. (2003). Cardiovascular protective effects of synthetic isoflavone derivatives in apolipoprotein E-deficient mice. J. Vasc. Res., 40, 276-284.
    • (2003) J. Vasc. Res. , vol.40 , pp. 276-284
    • Jiang, F.1    Jones, G.T.2    Husband, A.J.3    Dusting, G.J.4
  • 14
    • 0031884157 scopus 로고    scopus 로고
    • Estrogens increase transcription of the human endothelial NO synthase gene. Analysis of the transcription factors involved
    • KLEINERT, H., WALLERATH, T., EUCHENHOFER, C., IHRIGBIEDERT, I., LI, H. & FÖRSTERMANN, U. (1998). Estrogens increase transcription of the human endothelial NO synthase gene. Analysis of the transcription factors involved. Hypertension, 31, 582-588.
    • (1998) Hypertension , vol.31 , pp. 582-588
    • Kleinert, H.1    Wallerath, T.2    Euchenhofer, C.3    Ihrigbiedert, I.4    Li, H.5    Förstermann, U.6
  • 15
    • 0028838042 scopus 로고
    • Dietary protein and atherosclerosis: A review of the early history
    • KRITCHEVSKY, D. (1995). Dietary protein and atherosclerosis: a review of the early history. J. Nutr., 125, 589S-593S.
    • (1995) J. Nutr. , vol.125
    • Kritchevsky, D.1
  • 17
    • 0035812887 scopus 로고    scopus 로고
    • Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein
    • LEIKERT, J.F., RÄTHEL, T.R., MÜLLER, C., VOLLMAR, A.M. & DIRSCH, V.M. (2001). Reliable in vitro measurement of nitric oxide released from endothelial cells using low concentrations of the fluorescent probe 4,5-diaminofluorescein. FEBS lett., 506, 131-134.
    • (2001) FEBS Lett. , vol.506 , pp. 131-134
    • Leikert, J.F.1    Räthel, T.R.2    Müller, C.3    Vollmar, A.M.4    Dirsch, V.M.5
  • 18
    • 0342723791 scopus 로고    scopus 로고
    • Nitric oxide in the pathogenesis of vascular disease
    • LI, H. & FÖRSTERMANN, U. (2000). Nitric oxide in the pathogenesis of vascular disease. J. Pathol., 190, 244-254.
    • (2000) J. Pathol. , vol.190 , pp. 244-254
    • Li, H.1    Förstermann, U.2
  • 20
    • 0037446887 scopus 로고    scopus 로고
    • Plasma membrane localization and function of the estrogen receptor α variant (ER46) in human endothelial cells
    • LI, L., HAYNES, P. & BENDER, J.R. (2003). Plasma membrane localization and function of the estrogen receptor α variant (ER46) in human endothelial cells. Proc. Natl. Acad. Sci. U.S.A., 100, 4807-4812.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 4807-4812
    • Li, L.1    Haynes, P.2    Bender, J.R.3
  • 21
    • 0000961296 scopus 로고
    • Effect of high protein diets on experimental atherosclerosis of rabbits
    • MEEKER, D.R. & KESTEN, H.D. (1941). Effect of high protein diets on experimental atherosclerosis of rabbits. Arch. Pathol., 31, 147-162.
    • (1941) Arch. Pathol. , vol.31 , pp. 147-162
    • Meeker, D.R.1    Kesten, H.D.2
  • 22
    • 0346670255 scopus 로고    scopus 로고
    • Application of 4,5-diaminofluorescein to reliably measure nitric oxide released from endothelial cells in vitro
    • RÄTHEL, T.R., LEIKERT, J.F., VOLLMAR, A.M. & DIRSCH, V.M. (2003). Application of 4,5-diaminofluorescein to reliably measure nitric oxide released from endothelial cells in vitro. Biol. Proced. Online, 5, 146-152.
    • (2003) Biol. Proced. Online , vol.5 , pp. 146-152
    • Räthel, T.R.1    Leikert, J.F.2    Vollmar, A.M.3    Dirsch, V.M.4
  • 23
    • 0034705168 scopus 로고    scopus 로고
    • Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling
    • RUSSELL, K.S., HAYNES, M.P., SINHA, D., CLERISME, E. & BENDER, J.R. (2000). Human vascular endothelial cells contain membrane binding sites for estradiol, which mediate rapid intracellular signaling. Proc. Natl. Acad. Sci. U.S.A., 97, 5930-5935.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 5930-5935
    • Russell, K.S.1    Haynes, M.P.2    Sinha, D.3    Clerisme, E.4    Bender, J.R.5
  • 25
    • 0037830976 scopus 로고    scopus 로고
    • Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal woman
    • STEINBERG, F.M., GUTHRIE, N.L., VILLABLANCA, A.C., KUMAR, K. & MURRAY, M.J. (2003). Soy protein with isoflavones has favorable effects on endothelial function that are independent of lipid and antioxidant effects in healthy postmenopausal woman. Am. J. Clin. Nutr., 78, 123-130.
    • (2003) Am. J. Clin. Nutr. , vol.78 , pp. 123-130
    • Steinberg, F.M.1    Guthrie, N.L.2    Villablanca, A.C.3    Kumar, K.4    Murray, M.J.5
  • 26
    • 0344198493 scopus 로고    scopus 로고
    • Estrogen-related receptor α1 up-regulates endothelial nitric oxide synthase expression
    • SUMI, D. & IGNARRO, L.J. (2003). Estrogen-related receptor α1 up-regulates endothelial nitric oxide synthase expression. Proc. Natl. Acad. Sci. U.S.A., 100, 14451-14456.
    • (2003) Proc. Natl. Acad. Sci. U.S.A. , vol.100 , pp. 14451-14456
    • Sumi, D.1    Ignarro, L.J.2
  • 28
    • 0034056131 scopus 로고    scopus 로고
    • Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention
    • TIKKANEN, M.J. & ADLERCREUTZ, H. (2000). Dietary soy-derived isoflavone phytoestrogens. Could they have a role in coronary heart disease prevention. Biochem. Pharmacol., 60, 1-5.
    • (2000) Biochem. Pharmacol. , vol.60 , pp. 1-5
    • Tikkanen, M.J.1    Adlercreutz, H.2
  • 32
    • 3042543745 scopus 로고    scopus 로고
    • Effects of isoflavones (soy-phytoestrogens) on serum lipids : A meta-analysis of randomized controlled trials
    • YEUNG, J. & YU, T. (2003). Effects of isoflavones (soy-phytoestrogens) on serum lipids : a meta-analysis of randomized controlled trials. Nutr. J., 2, 15.
    • (2003) Nutr. J. , vol.2 , pp. 15
    • Yeung, J.1    Yu, T.2


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