-
1
-
-
0036905115
-
Cellular actions of the insulin-like growth factor binding proteins
-
10.1210/er.2001-0033
-
Firth SM, Baxter RC (2002) Cellular actions of the insulin-like growth factor binding proteins. Endocr Rev 23:824-854 10.1210/er.2001-0033
-
(2002)
Endocr. Rev.
, vol.23
, pp. 824-854
-
-
Firth, S.M.1
Baxter, R.C.2
-
2
-
-
85025577215
-
Genetic approaches to the function of insulin-like growth factor-binding proteins during rodent development
-
1:CAS:528:DyaK28XhvFKnurc%3D
-
Pintar JE, Cerro JA, Wood TL (1996) Genetic approaches to the function of insulin-like growth factor-binding proteins during rodent development. Horm Res 45:172-177 1:CAS:528:DyaK28XhvFKnurc%3D
-
(1996)
Horm. Res.
, vol.45
, pp. 172-177
-
-
Pintar, J.E.1
Cerro, J.A.2
Wood, T.L.3
-
3
-
-
0029432417
-
Genetic ablation of IGFBP-2 suggests functional redundancy in the IGFBP family
-
10.1016/0955-2235(95)00029-1
-
Pintar JE, Schuller A, Cerro JA, Czick M, Grewal A, Green B (1995) Genetic ablation of IGFBP-2 suggests functional redundancy in the IGFBP family. Prog Growth Factor Res 6:437-445 10.1016/0955-2235(95)00029-1
-
(1995)
Prog. Growth Factor Res.
, vol.6
, pp. 437-445
-
-
Pintar, J.E.1
Schuller, A.2
Cerro, J.A.3
Czick, M.4
Grewal, A.5
Green, B.6
-
4
-
-
0033734689
-
Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene
-
10.1210/me.14.9.1472
-
Wood TL, Rogler LE, Czick ME, Schuller AG, Pintar JE (2000) Selective alterations in organ sizes in mice with a targeted disruption of the insulin-like growth factor binding protein-2 gene. Mol Endocrinol 14:1472-1482 10.1210/me.14.9.1472
-
(2000)
Mol. Endocrinol.
, vol.14
, pp. 1472-1482
-
-
Wood, T.L.1
Rogler, L.E.2
Czick, M.E.3
Schuller, A.G.4
Pintar, J.E.5
-
5
-
-
0030999590
-
Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: Repercussions on reproduction, ante- and perinatal mortality and postnatal growth
-
10.1210/en.138.7.2937
-
Gay E, Seurin D, Babajko S, Doublier S, Cazillis M, Binoux M (1997) Liver-specific expression of human insulin-like growth factor binding protein-1 in transgenic mice: Repercussions on reproduction, ante- and perinatal mortality and postnatal growth. Endocrinology 138:2937-2947 10.1210/en.138.7.2937
-
(1997)
Endocrinology
, vol.138
, pp. 2937-2947
-
-
Gay, E.1
Seurin, D.2
Babajko, S.3
Doublier, S.4
Cazillis, M.5
Binoux, M.6
-
6
-
-
0029147073
-
Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice
-
10.1210/en.136.9.4029
-
Rajkumar K, Barron D, Lewitt MS, Murphy LJ (1995) Growth retardation and hyperglycemia in insulin-like growth factor binding protein-1 transgenic mice. Endocrinology 136:4029-4034 10.1210/en.136.9.4029
-
(1995)
Endocrinology
, vol.136
, pp. 4029-4034
-
-
Rajkumar, K.1
Barron, D.2
Lewitt, M.S.3
Murphy, L.J.4
-
7
-
-
0028152799
-
Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: An in vivo model for the analysis of igf function in the brain
-
7531120
-
D'Ercole AJ, Dai Z, Xing Y, Boney C, Wilkie MB, Lauder JM, Han VK, Clemmons DR (1994) Brain growth retardation due to the expression of human insulin like growth factor binding protein-1 in transgenic mice: an in vivo model for the analysis of igf function in the brain. Brain Res Dev Brain Res 82:213-222 7531120
-
(1994)
Brain Res. Dev. Brain Res.
, vol.82
, pp. 213-222
-
-
D'Ercole, A.J.1
Dai, Z.2
Xing, Y.3
Boney, C.4
Wilkie, M.B.5
Lauder, J.M.6
Han, V.K.7
Clemmons, D.R.8
-
8
-
-
0034088143
-
Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance
-
1:CAS:528:DC%2BD3cXlsFCqsr0%3D
-
Crossey PA, Jones JS, Miell JP (2000) Dysregulation of the insulin/IGF binding protein-1 axis in transgenic mice is associated with hyperinsulinemia and glucose intolerance. Diabetes 49:457-465 1:CAS:528:DC%2BD3cXlsFCqsr0%3D
-
(2000)
Diabetes
, vol.49
, pp. 457-465
-
-
Crossey, P.A.1
Jones, J.S.2
Miell, J.P.3
-
9
-
-
0034049930
-
Overexpression of insulin-like growth factor binding protein-1 in transgenic mice
-
10.1007/s004670000347
-
Murphy LJ (2000) Overexpression of insulin-like growth factor binding protein-1 in transgenic mice. Pediatr Nephrol 14:567-571 10.1007/ s004670000347
-
(2000)
Pediatr. Nephrol.
, vol.14
, pp. 567-571
-
-
Murphy, L.J.1
-
10
-
-
0036773465
-
Insights from insulin-like growth factor binding protein transgenic mice
-
10.1210/en.2002-220116
-
Silha JV, Murphy LJ (2002) Insights from insulin-like growth factor binding protein transgenic mice. Endocrinology 143:3711-3714 10.1210/ en.2002-220116
-
(2002)
Endocrinology
, vol.143
, pp. 3711-3714
-
-
Silha, J.V.1
Murphy, L.J.2
-
11
-
-
0030664841
-
Impaired brain development and reduced astrocyte response to injury in transgenic mice expressing IGF binding protein-1
-
10.1016/S0006-8993(97)00676-8
-
Ni W, Rajkumar K, Nagy JI, Murphy LJ (1997) Impaired brain development and reduced astrocyte response to injury in transgenic mice expressing IGF binding protein-1. Brain Res 769:97-107 10.1016/S0006-8993(97)00676-8
-
(1997)
Brain Res.
, vol.769
, pp. 97-107
-
-
Ni, W.1
Rajkumar, K.2
Nagy, J.I.3
Murphy, L.J.4
-
12
-
-
0033763635
-
Impaired brain development and hydrocephalus in a line of transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1
-
10.1054/ghir.2000.0168
-
Doublier S, Duyckaerts C, Seurin D, Binoux M (2000) Impaired brain development and hydrocephalus in a line of transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1. Growth Horm IGF Res 10:267-274 10.1054/ghir.2000.0168
-
(2000)
Growth Horm. IGF Res.
, vol.10
, pp. 267-274
-
-
Doublier, S.1
Duyckaerts, C.2
Seurin, D.3
Binoux, M.4
-
13
-
-
0033304640
-
Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain
-
10.1210/en.140.12.5488
-
Hoeflich A, Wu M, Mohan S, Foll J, Wanke R, Froehlich T, Arnold GJ, Lahm H, Kolb HJ, Wolf E (1999) Overexpression of insulin-like growth factor-binding protein-2 in transgenic mice reduces postnatal body weight gain. Endocrinology 140:5488-5496 10.1210/en.140.12.5488
-
(1999)
Endocrinology
, vol.140
, pp. 5488-5496
-
-
Hoeflich, A.1
Wu, M.2
Mohan, S.3
Foll, J.4
Wanke, R.5
Froehlich, T.6
Arnold, G.J.7
Lahm, H.8
Kolb, H.J.9
Wolf, E.10
-
14
-
-
0037125241
-
Mutation of the RGD sequence does not affect plasma membrane association and growth inhibitory effects of elevated IGFBP-2 in vivo
-
10.1016/S0014-5793(02)02935-6
-
Hoeflich A, Reisinger R, Vargas GA, Elmlinger MW, Schuett B, Jehle PM, Renner-Muller I, Lahm H, Russo VC, Wolf E (2002) Mutation of the RGD sequence does not affect plasma membrane association and growth inhibitory effects of elevated IGFBP-2 in vivo. FEBS Lett 523:63-67 10.1016/S0014-5793(02)02935-6
-
(2002)
FEBS Lett.
, vol.523
, pp. 63-67
-
-
Hoeflich, A.1
Reisinger, R.2
Vargas, G.A.3
Elmlinger, M.W.4
Schuett, B.5
Jehle, P.M.6
Renner-Muller, I.7
Lahm, H.8
Russo, V.C.9
Wolf, E.10
-
15
-
-
0035049816
-
Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2
-
10.1210/en.142.5.1889
-
Hoeflich A, Nedbal S, Blum WF, Erhard M, Lahm H, Brem G, Kolb HJ, Wanke R, Wolf E (2001) Growth inhibition in giant growth hormone transgenic mice by overexpression of insulin-like growth factor-binding protein-2. Endocrinology 142:1889-1898 10.1210/en.142.5.1889
-
(2001)
Endocrinology
, vol.142
, pp. 1889-1898
-
-
Hoeflich, A.1
Nedbal, S.2
Blum, W.F.3
Erhard, M.4
Lahm, H.5
Brem, G.6
Kolb, H.J.7
Wanke, R.8
Wolf, E.9
-
16
-
-
0036847603
-
Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/IGF-I excess on adrenocortical cells in vivo
-
10.1096/fj.02-0349com
-
Hoeflich A, Weber MM, Fisch T, Nedbal S, Fottner C, Elmlinger MW, Wanke R, Wolf E (2002) Insulin-like growth factor binding protein 2 (IGFBP-2) separates hypertrophic and hyperplastic effects of growth hormone (GH)/ IGF-I excess on adrenocortical cells in vivo. FASEB J 16:1721-1731 10.1096/fj.02-0349com
-
(2002)
FASEB J.
, vol.16
, pp. 1721-1731
-
-
Hoeflich, A.1
Weber, M.M.2
Fisch, T.3
Nedbal, S.4
Fottner, C.5
Elmlinger, M.W.6
Wanke, R.7
Wolf, E.8
-
17
-
-
0037099658
-
Essential role of PDK1 in regulating cell size and development in mice
-
10.1093/emboj/cdf387
-
Lawlor MA, Mora A, Ashby PR, Williams MR, Murray-Tait V, Malone L, Prescott AR, Lucocq JM, Alessi DR (2002) Essential role of PDK1 in regulating cell size and development in mice. EMBO J 21:3728-3738 10.1093/emboj/cdf387
-
(2002)
EMBO J.
, vol.21
, pp. 3728-3738
-
-
Lawlor, M.A.1
Mora, A.2
Ashby, P.R.3
Williams, M.R.4
Murray-Tait, V.5
Malone, L.6
Prescott, A.R.7
Lucocq, J.M.8
Alessi, D.R.9
-
18
-
-
14644443180
-
IGFBP-2 as a modulator of IGF-I/GH-induced signaling cascades: Effects on phosphorylation of PTEN and PDK
-
Hoeflich A, Schmidt S, Fisch T, Wanke R, Weber MM, Seufferlein T, Wolf E (2004) IGFBP-2 as a modulator of IGF-I/GH-induced signaling cascades: effects on phosphorylation of PTEN and PDK. Growth Horm IGF Res 14:111
-
(2004)
Growth Horm. IGF Res.
, vol.14
, pp. 111
-
-
Hoeflich, A.1
Schmidt, S.2
Fisch, T.3
Wanke, R.4
Weber, M.M.5
Seufferlein, T.6
Wolf, E.7
-
19
-
-
0036460582
-
Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice
-
Eckstein F, Pavicic T, Nedbal S, Schmidt C, Wehr U, Rambeck W, Wolf E, Hoeflich A (2002) Insulin-like growth factor-binding protein-2 (IGFBP-2) overexpression negatively regulates bone size and mass, but not density, in the absence and presence of growth hormone/IGF-I excess in transgenic mice. Anat Embryol (Berl) 206:139-148
-
(2002)
Anat. Embryol. (Berl.)
, vol.206
, pp. 139-148
-
-
Eckstein, F.1
Pavicic, T.2
Nedbal, S.3
Schmidt, C.4
Wehr, U.5
Rambeck, W.6
Wolf, E.7
Hoeflich, A.8
-
20
-
-
0036838455
-
Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice
-
1:CAS:528:DC%2BD38XovVOls7c%3D
-
Silha JV, Gui Y, Murphy LJ (2002) Impaired glucose homeostasis in insulin-like growth factor-binding protein-3-transgenic mice. Am J Physiol Endocrinol Metab 283: E937-E945 1:CAS:528:DC%2BD38XovVOls7c%3D
-
(2002)
Am. J. Physiol. Endocrinol. Metab.
, vol.283
-
-
Silha, J.V.1
Gui, Y.2
Murphy, L.J.3
-
21
-
-
0035043176
-
Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice
-
10.1210/en.142.5.1958
-
Modric T, Silha JV, Shi Z, Gui Y, Suwanichkul A, Durham SK, Powell DR, Murphy LJ (2001) Phenotypic manifestations of insulin-like growth factor-binding protein-3 overexpression in transgenic mice. Endocrinology 142:1958-1967 10.1210/en.142.5.1958
-
(2001)
Endocrinology
, vol.142
, pp. 1958-1967
-
-
Modric, T.1
Silha, J.V.2
Shi, Z.3
Gui, Y.4
Suwanichkul, A.5
Durham, S.K.6
Powell, D.R.7
Murphy, L.J.8
-
22
-
-
0028783276
-
Expression of human insulin-like growth factor-binding protein-3 in transgenic mice
-
1:CAS:528:DyaK2MXpvVGjtbw%3D
-
Murphy LJ, Molnar P, Lu X, Huang H (1995) Expression of human insulin-like growth factor-binding protein-3 in transgenic mice. J Mol Endocrinol 15:293-303 1:CAS:528:DyaK2MXpvVGjtbw%3D
-
(1995)
J. Mol. Endocrinol.
, vol.15
, pp. 293-303
-
-
Murphy, L.J.1
Molnar, P.2
Lu, X.3
Huang, H.4
-
23
-
-
0034802080
-
Overexpression of the acid-labile subunit of the IGF ternary complex in transgenic mice
-
10.1210/en.142.10.4305
-
Silha JV, Gui Y, Modric T, Suwanichkul A, Durham SK, Powell DR, Murphy LJ (2001) Overexpression of the acid-labile subunit of the IGF ternary complex in transgenic mice. Endocrinology 142:4305-4313 10.1210/ en.142.10.4305
-
(2001)
Endocrinology
, vol.142
, pp. 4305-4313
-
-
Silha, J.V.1
Gui, Y.2
Modric, T.3
Suwanichkul, A.4
Durham, S.K.5
Powell, D.R.6
Murphy, L.J.7
-
24
-
-
0029946896
-
Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model
-
1:CAS:528:DyaK28XjtFChtr8%3D
-
Neuenschwander S, Schwartz A, Wood TL, Roberts CT Jr, Hennighausen L, LeRoith D (1996) Involution of the lactating mammary gland is inhibited by the IGF system in a transgenic mouse model. J Clin Invest 97:2225-2232 1:CAS:528:DyaK28XjtFChtr8%3D
-
(1996)
J. Clin. Invest.
, vol.97
, pp. 2225-2232
-
-
Neuenschwander, S.1
Schwartz, A.2
Wood, T.L.3
Roberts Jr., C.T.4
Hennighausen, L.5
LeRoith, D.6
-
25
-
-
0029434889
-
Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: Studies in transgenic mice
-
10.1016/0955-2235(96)00009-9
-
LeRoith D, Neuenschwander S, Wood TL, Hennighausen L (1995) Insulin-like growth factor-I and insulin-like growth factor binding protein-3 inhibit involution of the mammary gland following lactation: Studies in transgenic mice. Prog Growth Factor Res 6:433-436 10.1016/ 0955-2235(96)00009-9
-
(1995)
Prog. Growth Factor Res.
, vol.6
, pp. 433-436
-
-
LeRoith, D.1
Neuenschwander, S.2
Wood, T.L.3
Hennighausen, L.4
-
26
-
-
0042855006
-
IGF-binding protein-4: Biochemical characteristics and functional consequences
-
1:CAS:528:DC%2BD3sXmvFGns7s%3D
-
Zhou R, Diehl D, Hoeflich A, Lahm H, Wolf E (2003) IGF-binding protein-4: Biochemical characteristics and functional consequences. J Endocrinol 178:177-193 1:CAS:528:DC%2BD3sXmvFGns7s%3D
-
(2003)
J. Endocrinol.
, vol.178
, pp. 177-193
-
-
Zhou, R.1
Diehl, D.2
Hoeflich, A.3
Lahm, H.4
Wolf, E.5
-
27
-
-
1642372201
-
Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms
-
1:CAS:528:DC%2BD2cXhslektbw%3D
-
Diehl D, Hoeflich A, Wolf E, Lahm H (2004) Insulin-like growth factor (IGF)-binding protein-4 inhibits colony formation of colorectal cancer cells by IGF-independent mechanisms. Cancer Res 64:1600-1603 1:CAS:528:DC%2BD2cXhslektbw%3D
-
(2004)
Cancer Res.
, vol.64
, pp. 1600-1603
-
-
Diehl, D.1
Hoeflich, A.2
Wolf, E.3
Lahm, H.4
-
28
-
-
0031790160
-
Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia
-
10.1210/en.139.5.2605
-
Wang J, Niu W, Witte DP, Chernausek SD, Nikiforov YE, Clemens TL, Sharifi B, Strauch AR, Fagin JA (1998) Overexpression of insulin-like growth factor-binding protein-4 (IGFBP-4) in smooth muscle cells of transgenic mice through a smooth muscle alpha-actin-IGFBP-4 fusion gene induces smooth muscle hypoplasia. Endocrinology 139:2605-2614 10.1210/ en.139.5.2605
-
(1998)
Endocrinology
, vol.139
, pp. 2605-2614
-
-
Wang, J.1
Niu, W.2
Witte, D.P.3
Chernausek, S.D.4
Nikiforov, Y.E.5
Clemens, T.L.6
Sharifi, B.7
Strauch, A.R.8
Fagin, J.A.9
-
29
-
-
0142027567
-
Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation
-
1:CAS:528:DC%2BD3sXjslahsrs%3D
-
Zhang M, Faugere MC, Malluche H, Rosen CJ, Chernausek SD, Clemens TL (2003) Paracrine overexpression of IGFBP-4 in osteoblasts of transgenic mice decreases bone turnover and causes global growth retardation. J Bone Miner Res 18:836-843 1:CAS:528:DC%2BD3sXjslahsrs%3D
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 836-843
-
-
Zhang, M.1
Faugere, M.C.2
Malluche, H.3
Rosen, C.J.4
Chernausek, S.D.5
Clemens, T.L.6
-
30
-
-
2342614217
-
Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice
-
1:CAS:528:DC%2BD2cXjslKjtrs%3D
-
Zhou R, Flaswinkel H, Schneider MR, Lahm H, Hoeflich A, Wanke R, Wolf E (2004) Insulin-like growth factor-binding protein-4 inhibits growth of the thymus in transgenic mice. J Mol Endocrinol 32:349-364 1:CAS:528:DC%2BD2cXjslKjtrs%3D
-
(2004)
J. Mol. Endocrinol.
, vol.32
, pp. 349-364
-
-
Zhou, R.1
Flaswinkel, H.2
Schneider, M.R.3
Lahm, H.4
Hoeflich, A.5
Wanke, R.6
Wolf, E.7
-
31
-
-
1642569707
-
Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice
-
Salih DA, Tripathi G, Holding C, Szestak TA, Gonzalez MI, Carter EJ, Cobb LJ, Eisemann JE, Pell JM (2004) Insulin-like growth factor-binding protein 5 (Igfbp5) compromises survival, growth, muscle development, and fertility in mice. Proc Natl Acad Sci USA 101:4314-4319
-
(2004)
Proc. Natl. Acad. Sci. USA
, vol.101
, pp. 4314-4319
-
-
Salih, D.A.1
Tripathi, G.2
Holding, C.3
Szestak, T.A.4
Gonzalez, M.I.5
Carter, E.J.6
Cobb, L.J.7
Eisemann, J.E.8
Pell, J.M.9
-
32
-
-
0036773550
-
Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia
-
10.1210/en.2002-220129
-
Devlin RD, Du Z, Buccilli V, Jorgetti V, Canalis E (2002) Transgenic mice overexpressing insulin-like growth factor binding protein-5 display transiently decreased osteoblastic function and osteopenia. Endocrinology 143:3955-3962 10.1210/en.2002-220129
-
(2002)
Endocrinology
, vol.143
, pp. 3955-3962
-
-
Devlin, R.D.1
Du, Z.2
Buccilli, V.3
Jorgetti, V.4
Canalis, E.5
-
33
-
-
0034470215
-
Insulin-like growth factor binding protein-5 (IGFBP-5) potentially regulates programmed cell death and plasminogen activation in the mammary gland
-
1:CAS:528:DC%2BD38XntFSmsrg%3D
-
Tonner E, Allan G, Shkreta L, Webster J, Whitelaw CB, Flint DJ (2000) Insulin-like growth factor binding protein-5 (IGFBP-5) potentially regulates programmed cell death and plasminogen activation in the mammary gland. Adv Exp Med Biol 480:45-53 1:CAS:528:DC%2BD38XntFSmsrg%3D
-
(2000)
Adv. Exp. Med. Biol.
, vol.480
, pp. 45-53
-
-
Tonner, E.1
Allan, G.2
Shkreta, L.3
Webster, J.4
Whitelaw, C.B.5
Flint, D.J.6
-
34
-
-
0036798203
-
Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice
-
1:CAS:528:DC%2BD38XotFGls74%3D
-
Tonner E, Barber MC, Allan GJ, Beattie J, Webster J, Whitelaw CB, Flint DJ (2002) Insulin-like growth factor binding protein-5 (IGFBP-5) induces premature cell death in the mammary glands of transgenic mice. Development 129:4547-4557 1:CAS:528:DC%2BD38XotFGls74%3D
-
(2002)
Development
, vol.129
, pp. 4547-4557
-
-
Tonner, E.1
Barber, M.C.2
Allan, G.J.3
Beattie, J.4
Webster, J.5
Whitelaw, C.B.6
Flint, D.J.7
-
35
-
-
2042503711
-
Insulin-like growth factor binding rotein-6 transgenic mice: Postnatal growth, brain development, and reproduction abnormalities
-
10.1210/en.2003-1196
-
Bienvenu G, Seurin D, Grellier P, Froment P, Baudrimont M, Monget P, Le Bouc Y, Babajko S (2004) Insulin-like growth factor binding protein-6 transgenic mice: Postnatal growth, brain development, and reproduction abnormalities. Endocrinology 145:2412-2420 10.1210/en.2003-1196
-
(2004)
Endocrinology
, vol.145
, pp. 2412-2420
-
-
Bienvenu, G.1
Seurin, D.2
Grellier, P.3
Froment, P.4
Baudrimont, M.5
Monget, P.6
Le Bouc, Y.7
Babajko, S.8
-
36
-
-
0029861209
-
Impaired glucose homeostasis in insulin-like growth factor binding protein-1 transgenic mice
-
1:CAS:528:DyaK28XmtlOkurc%3D
-
Rajkumar K, Krsek M, Dheen ST, Murphy LJ (1996) Impaired glucose homeostasis in insulin-like growth factor binding protein-1 transgenic mice. J Clin Invest 98:1818-1825 1:CAS:528:DyaK28XmtlOkurc%3D
-
(1996)
J. Clin. Invest.
, vol.98
, pp. 1818-1825
-
-
Rajkumar, K.1
Krsek, M.2
Dheen, S.T.3
Murphy, L.J.4
-
37
-
-
15844383627
-
Hyperglycemia and impaired glucose tolerance in IGF binding protein-1 transgenic mice
-
1:CAS:528:DyaK28Xis1enurg%3D
-
Rajkumar K, Dheen ST, Murphy LJ (1996) Hyperglycemia and impaired glucose tolerance in IGF binding protein-1 transgenic mice. Am J Physiol 270: E565-E571 1:CAS:528:DyaK28Xis1enurg%3D
-
(1996)
Am. J. Physiol.
, vol.270
-
-
Rajkumar, K.1
Dheen, S.T.2
Murphy, L.J.3
-
38
-
-
0033060656
-
Enhanced gluconeogenesis and hepatic insulin resistance in insulin-like growth factor binding protein-1 transgenic mice
-
10.1016/S0304-4165(98)00162-7
-
Rajkumar K, Murphy LJ (1999) Enhanced gluconeogenesis and hepatic insulin resistance in insulin-like growth factor binding protein-1 transgenic mice. Biochim Biophys Acta 1426:491-497 10.1016/ S0304-4165(98)00162-7
-
(1999)
Biochim. Biophys. Acta
, vol.1426
, pp. 491-497
-
-
Rajkumar, K.1
Murphy, L.J.2
-
39
-
-
0030733291
-
Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice
-
1:CAS:528:DyaK2sXnvVGhtLc%3D
-
Dheen ST, Rajkumar K, Murphy LJ (1997) Islet cell proliferation and apoptosis in insulin-like growth factor binding protein-1 in transgenic mice. J Endocrinol 155:551-558 1:CAS:528:DyaK2sXnvVGhtLc%3D
-
(1997)
J. Endocrinol.
, vol.155
, pp. 551-558
-
-
Dheen, S.T.1
Rajkumar, K.2
Murphy, L.J.3
-
40
-
-
0031029657
-
Reduced fecundity in insulin-like growth factor-binding protein-1 transgenic mice
-
1:CAS:528:DyaK2sXislahsw%3D%3D
-
Huang H, Rajkumar K, Murphy LJ (1997) Reduced fecundity in insulin-like growth factor-binding protein-1 transgenic mice. Biol Reprod 56:284-289 1:CAS:528:DyaK2sXislahsw%3D%3D
-
(1997)
Biol. Reprod.
, vol.56
, pp. 284-289
-
-
Huang, H.1
Rajkumar, K.2
Murphy, L.J.3
-
41
-
-
0036225313
-
Reproductive abnormalities in human IGF binding protein-1 transgenic female mice
-
10.1210/en.143.5.1801
-
Froment P, Seurin D, Hembert S, Levine JE, Pisselet C, Monniaux D, Binoux M, Monget P (2002) Reproductive abnormalities in human IGF binding protein-1 transgenic female mice. Endocrinology 143:1801-1808 10.1210/en.143.5.1801
-
(2002)
Endocrinology
, vol.143
, pp. 1801-1808
-
-
Froment, P.1
Seurin, D.2
Hembert, S.3
Levine, J.E.4
Pisselet, C.5
Monniaux, D.6
Binoux, M.7
Monget, P.8
-
42
-
-
12144289952
-
Reproductive abnormalities in human insulin-like growth factor-binding protein-1 transgenic male mice
-
10.1210/en.2003-0956
-
Froment P, Staub C, Hembert S, Pisselet C, Magistrini M, Delaleu B, Seurin D, Levine JE, Johnson L, Binoux M, Monget P (2004) Reproductive abnormalities in human insulin-like growth factor-binding protein-1 transgenic male mice. Endocrinology 145:2080-2091 10.1210/en.2003-0956
-
(2004)
Endocrinology
, vol.145
, pp. 2080-2091
-
-
Froment, P.1
Staub, C.2
Hembert, S.3
Pisselet, C.4
Magistrini, M.5
Delaleu, B.6
Seurin, D.7
Levine, J.E.8
Johnson, L.9
Binoux, M.10
Monget, P.11
-
43
-
-
1542531902
-
'Designer' tumors in mice
-
10.1038/sj.onc.1207275
-
Politi K, Kljuic A, Szabolcs M, Fisher P, Ludwig T, Efstratiadis A (2004) 'Designer' tumors in mice. Oncogene 23:1558-1565 10.1038/ sj.onc.1207275
-
(2004)
Oncogene
, vol.23
, pp. 1558-1565
-
-
Politi, K.1
Kljuic, A.2
Szabolcs, M.3
Fisher, P.4
Ludwig, T.5
Efstratiadis, A.6
-
44
-
-
0000769033
-
Derangements of the somatotropic hormone axis in chronic renal failure
-
1:STN:280:ByiB38%2FnvFE%3D
-
Tonshoff B, Blum WF, Mehls O (1997) Derangements of the somatotropic hormone axis in chronic renal failure. Kidney Int 58:S106-S113 1:STN:280:ByiB38%2FnvFE%3D
-
(1997)
Kidney Int.
, vol.58
-
-
Tonshoff, B.1
Blum, W.F.2
Mehls, O.3
-
45
-
-
0032469370
-
Altered growth of mice divergently selected for body weight is associated with complex changes in the growth hormone/insulin-like growth factor system
-
1:CAS:528:DyaK1cXlt1eit74%3D
-
Hoeflich A, Schmidt P, Foll J, Rottmann O, Weber MM, Kolb HJ, Pirchner F, Wolf E (1998) Altered growth of mice divergently selected for body weight is associated with complex changes in the growth hormone/ insulin-like growth factor system. Growth Horm IGF Res 8:113-123 1:CAS:528:DyaK1cXlt1eit74%3D
-
(1998)
Growth Horm. IGF Res.
, vol.8
, pp. 113-123
-
-
Hoeflich, A.1
Schmidt, P.2
Foll, J.3
Rottmann, O.4
Weber, M.M.5
Kolb, H.J.6
Pirchner, F.7
Wolf, E.8
-
46
-
-
1542509346
-
Growth selection in mice reveals conserved and redundant expression patterns of the insulin-like growth factor system
-
10.1016/j.ygcen.2003.12.019
-
Hoeflich A, Bunger L, Nedbal S, Renne U, Elmlinger MW, Blum WF, Bruley C, Kolb HJ, Wolf E (2004) Growth selection in mice reveals conserved and redundant expression patterns of the insulin-like growth factor system. Gen Comp Endocrinol 136:248-259 10.1016/j.ygcen.2003.12.019
-
(2004)
Gen. Comp. Endocrinol.
, vol.136
, pp. 248-259
-
-
Hoeflich, A.1
Bunger, L.2
Nedbal, S.3
Renne, U.4
Elmlinger, M.W.5
Blum, W.F.6
Bruley, C.7
Kolb, H.J.8
Wolf, E.9
-
47
-
-
0027496895
-
Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)
-
10.1016/0092-8674(93)90679-K
-
Liu JP, Baker J, Perkins AS, Robertson EJ, Efstratiadis A (1993) Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r). Cell 75:59-72 10.1016/ 0092-8674(93)90679-K
-
(1993)
Cell
, vol.75
, pp. 59-72
-
-
Liu, J.P.1
Baker, J.2
Perkins, A.S.3
Robertson, E.J.4
Efstratiadis, A.5
-
48
-
-
0028941681
-
Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons
-
10.1016/0896-6273(95)90216-3
-
Beck KD, Powell-Braxton L, Widmer HR, Valverde J, Hefti F (1995) Igf1 gene disruption results in reduced brain size, CNS hypomyelination, and loss of hippocampal granule and striatal parvalbumin-containing neurons. Neuron 14:717-730 10.1016/0896-6273(95)90216-3
-
(1995)
Neuron
, vol.14
, pp. 717-730
-
-
Beck, K.D.1
Powell-Braxton, L.2
Widmer, H.R.3
Valverde, J.4
Hefti, F.5
-
49
-
-
0036463244
-
Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice
-
10.1054/ghir.2002.0261
-
Lahm H, Gittner K, Krebs O, Sprague L, Deml E, Oesterle D, Hoeflich A, Wanke R, Wolf E (2002) Diethylnitrosamine induces long-lasting re-expression of insulin-like growth factor II during early stages of liver carcinogenesis in mice. Growth Horm IGF Res 12:69-79 10.1054/ ghir.2002.0261
-
(2002)
Growth Horm. IGF Res.
, vol.12
, pp. 69-79
-
-
Lahm, H.1
Gittner, K.2
Krebs, O.3
Sprague, L.4
Deml, E.5
Oesterle, D.6
Hoeflich, A.7
Wanke, R.8
Wolf, E.9
-
50
-
-
0037357470
-
Associations between tissue-specific DNA alkylation, DNA repair and cell proliferation in the colon and colon tumour yield in mice treated with 1,2-dimethylhydrazine
-
10.1093/carcin/24.3.527
-
Jackson PE, O'Connor PJ, Cooper DP, Margison GP, Povey AC (2003) Associations between tissue-specific DNA alkylation, DNA repair and cell proliferation in the colon and colon tumour yield in mice treated with 1,2-dimethylhydrazine. Carcinogenesis 24:527-533 10.1093/carcin/24.3.527
-
(2003)
Carcinogenesis
, vol.24
, pp. 527-533
-
-
Jackson, P.E.1
O'Connor, P.J.2
Cooper, D.P.3
Margison, G.P.4
Povey, A.C.5
-
51
-
-
0035040824
-
Overexpression of human insulin-like growth factor binding protein-1 in the mouse leads to nephron deficit
-
1:CAS:528:DC%2BD3MXjvFKhur8%3D
-
Doublier S, Amri K, Seurin D, Moreau E, Merlet-Benichou C, Striker GE, Gilbert T 2001 Overexpression of human insulin-like growth factor binding protein-1 in the mouse leads to nephron deficit Pediatr Res 49:660-666 1:CAS:528:DC%2BD3MXjvFKhur8%3D
-
(2001)
Pediatr. Res.
, vol.49
, pp. 660-666
-
-
Doublier, S.1
Amri, K.2
Seurin, D.3
Moreau, E.4
Merlet-Benichou, C.5
Striker, G.E.6
Gilbert, T.7
-
52
-
-
0034035697
-
Glomerulosclerosis in mice transgenic for human insulin-like growth factor-binding protein-1
-
10.1046/j.1523-1755.2000.00090.x
-
Doublier S, Seurin D, Fouqueray B, Verpont MC, Callard P, Striker LJ, Striker GE, Binoux M, Baud L (2000) Glomerulosclerosis in mice transgenic for human insulin-like growth factor-binding protein-1. Kidney Int 57:2299-2307 10.1046/j.1523-1755.2000.00090.x
-
(2000)
Kidney Int.
, vol.57
, pp. 2299-2307
-
-
Doublier, S.1
Seurin, D.2
Fouqueray, B.3
Verpont, M.C.4
Callard, P.5
Striker, L.J.6
Striker, G.E.7
Binoux, M.8
Baud, L.9
-
53
-
-
0036068641
-
Bone formation in the context of growth retardation induced by hIGFBP-1 overexpression in transgenic mice
-
12489207
-
Ben Lagha N, Menuelle P, Seurin D, Binoux M, Lebouc Y, Berdal A (2002) Bone formation in the context of growth retardation induced by hIGFBP-1 overexpression in transgenic mice. Connect Tissue Res 43:515-519 12489207
-
(2002)
Connect. Tissue Res.
, vol.43
, pp. 515-519
-
-
Ben Lagha, N.1
Menuelle, P.2
Seurin, D.3
Binoux, M.4
Lebouc, Y.5
Berdal, A.6
-
54
-
-
85047686654
-
Functional alteration of the somatotrophic axis in transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1
-
10.1203/01.PDR.0000019550.58488.53
-
Seurin D, Froment P, Bluet-Pajot MT, Epelbaum J, Monget P, Binoux M (2002) Functional alteration of the somatotrophic axis in transgenic mice with liver-specific expression of human insulin-like growth factor binding protein-1. Pediatr Res 52:168-174 10.1203/ 01.PDR.0000019550.58488.53
-
(2002)
Pediatr. Res.
, vol.52
, pp. 168-174
-
-
Seurin, D.1
Froment, P.2
Bluet-Pajot, M.T.3
Epelbaum, J.4
Monget, P.5
Binoux, M.6
-
55
-
-
0032858944
-
Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice
-
1:CAS:528:DyaK1MXmtFChs7g%3D
-
Rajkumar K, Modric T, Murphy LJ (1999) Impaired adipogenesis in insulin-like growth factor binding protein-1 transgenic mice. J Endocrinol 162:457-465 1:CAS:528:DyaK1MXmtFChs7g%3D
-
(1999)
J. Endocrinol.
, vol.162
, pp. 457-465
-
-
Rajkumar, K.1
Modric, T.2
Murphy, L.J.3
-
56
-
-
0029919566
-
Impaired estrogen action in the uterus of insulin-like growth factor binding protein-1 transgenic mice
-
10.1210/en.137.4.1258
-
Rajkumar K, Dheen T, Krsek M, Murphy LJ (1996) Impaired estrogen action in the uterus of insulin-like growth factor binding protein-1 transgenic mice. Endocrinology 137:1258-1264 10.1210/en.137.4.1258
-
(1996)
Endocrinology
, vol.137
, pp. 1258-1264
-
-
Rajkumar, K.1
Dheen, T.2
Krsek, M.3
Murphy, L.J.4
-
57
-
-
0029433778
-
Phenotypic manifestations of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 overexpression in transgenic mice
-
10.1016/0955-2235(95)00026-7
-
Murphy LJ, Rajkumar K, Molnar P (1995) Phenotypic manifestations of insulin-like growth factor binding protein-1 (IGFBP-1) and IGFBP-3 overexpression in transgenic mice. Prog Growth Factor Res 6:425-432 10.1016/0955-2235(95)00026-7
-
(1995)
Prog. Growth Factor Res.
, vol.6
, pp. 425-432
-
-
Murphy, L.J.1
Rajkumar, K.2
Molnar, P.3
-
58
-
-
0032780262
-
Thyroid gland function and growth in IGF binding protein-1 transgenic mice
-
1:CAS:528:DyaK1MXlslSht7o%3D
-
Modric T, Rajkumar K, Murphy LJ (1999) Thyroid gland function and growth in IGF binding protein-1 transgenic mice. Eur J Endocrinol 141:149-159 1:CAS:528:DyaK1MXlslSht7o%3D
-
(1999)
Eur. J. Endocrinol.
, vol.141
, pp. 149-159
-
-
Modric, T.1
Rajkumar, K.2
Murphy, L.J.3
-
59
-
-
0033024788
-
Hepatic regeneration in insulin-like growth factor binding protein-1 transgenic mice
-
10.1016/S0168-8278(99)80199-8
-
Liu YY, Rajkumar K, Murphy LJ (1999) Hepatic regeneration in insulin-like growth factor binding protein-1 transgenic mice. J Hepatol 30:674-680 10.1016/S0168-8278(99)80199-8
-
(1999)
J. Hepatol.
, vol.30
, pp. 674-680
-
-
Liu, Y.Y.1
Rajkumar, K.2
Murphy, L.J.3
-
60
-
-
0031030656
-
Expression of insulin-like growth factor binding proteins (IGFBPs) in IGFBP-1 transgenic mice
-
1:CAS:528:DyaK2sXivVOgsrw%3D
-
Huang H, Rajkumar K, Murphy LJ (1997) Expression of insulin-like growth factor binding proteins (IGFBPs) in IGFBP-1 transgenic mice. J Endocrinol 152:99-108 1:CAS:528:DyaK2sXivVOgsrw%3D
-
(1997)
J. Endocrinol.
, vol.152
, pp. 99-108
-
-
Huang, H.1
Rajkumar, K.2
Murphy, L.J.3
-
61
-
-
0029969719
-
Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice
-
10.1007/s001250050566
-
Dheen ST, Rajkumar K, Murphy LJ (1996) Effects of insulin-like growth factors (IGF) on pancreatic islet function in IGF binding protein-1 transgenic mice. Diabetologia 39:1249-1254 10.1007/s001250050566
-
(1996)
Diabetologia
, vol.39
, pp. 1249-1254
-
-
Dheen, S.T.1
Rajkumar, K.2
Murphy, L.J.3
-
62
-
-
0029592609
-
Insulin-like growth factor-I influences the initiation of myelination: Studies of the anterior commissure of transgenic mice
-
10.1016/0304-3940(95)12194-3
-
Ye P, Carson J, D'Ercole AJ (1995) Insulin-like growth factor-I influences the initiation of myelination: Studies of the anterior commissure of transgenic mice. Neurosci Lett 201:235-238 10.1016/ 0304-3940(95)12194-3
-
(1995)
Neurosci. Lett.
, vol.201
, pp. 235-238
-
-
Ye, P.1
Carson, J.2
D'Ercole, A.J.3
-
63
-
-
0028865130
-
In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: Studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice
-
1:CAS:528:DyaK2MXptlOms74%3D
-
Ye P, Carson J, D'Ercole AJ (1995) In vivo actions of insulin-like growth factor-I (IGF-I) on brain myelination: Studies of IGF-I and IGF binding protein-1 (IGFBP-1) transgenic mice. J Neurosci 15:7344-7356 1:CAS:528:DyaK2MXptlOms74%3D
-
(1995)
J. Neurosci.
, vol.15
, pp. 7344-7356
-
-
Ye, P.1
Carson, J.2
D'Ercole, A.J.3
-
64
-
-
0030472414
-
In vivo effects of insulin-like growth factor-I on the development of sensory pathways: Analysis of the primary somatic sensory cortex (S1) of transgenic mice
-
10.1210/en.137.12.5484
-
Gutierrez-Ospina G, Calikoglu AS, Ye P, D'Ercole AJ (1996) In vivo effects of insulin-like growth factor-I on the development of sensory pathways: Analysis of the primary somatic sensory cortex (S1) of transgenic mice. Endocrinology 137:5484-5492 10.1210/en.137.12.5484
-
(1996)
Endocrinology
, vol.137
, pp. 5484-5492
-
-
Gutierrez-Ospina, G.1
Calikoglu, A.S.2
Ye, P.3
D'Ercole, A.J.4
-
65
-
-
0037338296
-
Insulin-like growth factor binding protein-1 over-expression in transgenic mice inhibits hepatic preneoplasia
-
10.1002/mc.10105
-
Lu S, Archer MC (2003) Insulin-like growth factor binding protein-1 over-expression in transgenic mice inhibits hepatic preneoplasia. Mol Carcinog 36:142-146 10.1002/mc.10105
-
(2003)
Mol. Carcinog.
, vol.36
, pp. 142-146
-
-
Lu, S.1
Archer, M.C.2
-
66
-
-
0036324652
-
Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice
-
10.1172/JCI200210077
-
Crossey PA, Pillai CC, Miell JP (2002) Altered placental development and intrauterine growth restriction in IGF binding protein-1 transgenic mice. J Clin Invest 110:411-418 10.1172/JCI200210077
-
(2002)
J. Clin. Invest.
, vol.110
, pp. 411-418
-
-
Crossey, P.A.1
Pillai, C.C.2
Miell, J.P.3
-
67
-
-
0041765677
-
Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1
-
1:CAS:528:DC%2BD3sXlvFCgtLg%3D
-
Wheatcroft SB, Kearney MT, Shah AM, Grieve DJ, Williams IL, Miell JP, Crossey PA (2003) Vascular endothelial function and blood pressure homeostasis in mice overexpressing IGF binding protein-1. Diabetes 52:2075-2082 1:CAS:528:DC%2BD3sXlvFCgtLg%3D
-
(2003)
Diabetes
, vol.52
, pp. 2075-2082
-
-
Wheatcroft, S.B.1
Kearney, M.T.2
Shah, A.M.3
Grieve, D.J.4
Williams, I.L.5
Miell, J.P.6
Crossey, P.A.7
-
68
-
-
0142210071
-
Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice
-
1:CAS:528:DC%2BD3sXosFynsrg%3D
-
Silha JV, Mishra S, Rosen CJ, Beamer WG, Turner RT, Powell DR, Murphy LJ (2003) Perturbations in bone formation and resorption in insulin-like growth factor binding protein-3 transgenic mice. J Bone Miner Res 18:1834-1841 1:CAS:528:DC%2BD3sXosFynsrg%3D
-
(2003)
J. Bone Miner. Res.
, vol.18
, pp. 1834-1841
-
-
Silha, J.V.1
Mishra, S.2
Rosen, C.J.3
Beamer, W.G.4
Turner, R.T.5
Powell, D.R.6
Murphy, L.J.7
|