Activity profiles of deoxynucleoside kinases and 5′-nucleotidases in cultured adipocytes and myoblastic cells: Insights into mitochondrial toxicity of nucleoside analogs

Biochemical Pharmacology

Volumn 69, Issue 6, 2005, Pages 951-960

  Rylova, Svetlana N ^a   Albertioni, Freidoun ^b   Flygh, Gunnar ^a   Eriksson, Staffan ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b KAROLINSKA UNIVERSITY HOSPITAL   (Sweden)

Author keywords

5 Nucleotidases; Adipocytes; Deoxynucleoside kinases; Mitochondrial toxicity; Myoblasts; NRTI

Indexed keywords

5' NUCLEOTIDASE; CELL EXTRACT; DEOXYCYTIDINE KINASE; DEOXYGUANOSINE KINASE; DEOXYRIBONUCLEOTIDASE; MESSENGER RNA; MITOCHONDRIAL ENZYME; PHOSPHOTRANSFERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; THYMIDINE KINASE; THYMIDINE KINASE 1; THYMIDINE KINASE 2; THYMIDYLATE KINASE; UNCLASSIFIED DRUG; ZIDOVUDINE;

ADIPOCYTE; ADIPOSE TISSUE; ANIMAL CELL; ARTICLE; BLOOD CELL; CELL CULTURE; CELL DIFFERENTIATION; CELL PROLIFERATION; CELL STRAIN 3T3; CONTROLLED STUDY; CYTOSOL; DRUG DETERMINATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME SPECIFICITY; MITOCHONDRIAL TOXICITY; MOUSE; MUSCLE TISSUE; MYOBLAST; NONHUMAN; PRIORITY JOURNAL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; T LYMPHOCYTE;

EID: 14644392828     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2004.12.010     Document Type: Article

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