Environmental Health Criteria 230: Nitrobenzene

Environmental Health Criteria

Volumn , Issue 230, 2003, Pages

  Davies, L ^a  

^a THERAPEUTIC GOODS ADMINISTRATION   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADDITIVES; AIR; ALCOHOLS; BOILING LIQUIDS; DEGRADATION; ENVIRONMENTAL IMPACT; FIRE HAZARDS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; MELTING; METABOLITES; ODOR CONTROL; PHOTOLYSIS; POLYURETHANES; SOLUBILITY; SUBSTITUTION REACTIONS; WATER;

ANILINE; ENVIRONMENTAL HEALTH; MELTING POINT; NITROBENZENE;

AROMATIC COMPOUNDS;

4 NITROPHENOL; ANILINE DERIVATIVE; NITROBENZENE; NITROBENZENE DERIVATIVE; ORGANOPHOSPHATE INSECTICIDE; PARATHION; PARATHION METHYL; PETROLEUM;

AIR ANALYSIS; AIR POLLUTION; ANALYTIC METHOD; BIOACCUMULATION; BLOOD TOXICITY; CARCINOGENICITY; CHEMICAL MODIFICATION; CHRONIC TOXICITY; CONCENTRATION (PARAMETERS); EMBRYOTOXICITY; ENVIRONMENTAL EXPOSURE; ENVIRONMENTAL MONITORING; FETOTOXICITY; HEALTH HAZARD; HUMAN; IMMUNOTOXICITY; INTOXICATION; KINETICS; LC 50; LIVER TOXICITY; LONG TERM EXPOSURE; METABOLISM; METHEMOGLOBINEMIA; MICROBIAL DEGRADATION; NEUROTOXICITY; NONHUMAN; OCCUPATIONAL EXPOSURE; OLIGOSPERMIA; PHOTOLYSIS; PHYSICAL CHEMISTRY; POLLUTION TRANSPORT; PRACTICE GUIDELINE; REPRODUCTIVE TOXICITY; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; REVIEW; RISK ASSESSMENT; SPLEEN DISEASE; TECHNIQUE; TERATOGENICITY; TESTIS ATROPHY; TOXICITY TESTING; WATER ANALYSIS; WATER CONTAMINATION; WORKPLACE;

EID: 14544272849     PISSN: 0250863X     EISSN: None     Source Type: Book Series    
DOI: None     Document Type: Review

References (499)

1. Abbinante R & Pasqualato D (1997) Intoxication due to ingestion of bitter almond oil contaminated with nitrobenzene. Toxicologist, 36(1), Part 2, Poster 218.
2. Abe S & Sasaki M (1977) Chromosome aberrations and sister chromatid exchanges in Chinese hamster cells exposed to various chemicals. J Natl Cancer Inst, 58: 1635-1641.
3. ACGIH (1991) Documentation of the threshold limit values and biological exposure indices, 6th ed. Cincinnati, Ohio, American Conference of Governmental Industrial Hygienists, vol 2, pp 1096-1099.
4. ACGIH (1995) 1995-1996 threshold limit values (TLVs) for chemical substances and physical agents and biological exposure indices (BEIs). Cincinnati, Ohio, American Conference of Governmental Industrial Hygienists, pp 28, 65.
5. ACGIH (2000) 2000 TLVs® and BEIs®. Cincinnati, Ohio, American Conference of Governmental Industrial Hygienists, p 100.
6. Acosta de Pérez O, Bemacchi AS, Diaz de Toranzo EG, & Castro JA (1992) Reductive biotransformation of xenobiotics by the sheep ruminal content. Comp Biochem Physiol C, 101: 625-626.
7. Adkins RL (1996) Nitrobenzene and nitrotoluenes. In: Kroschwitz JI & Howe-Grant M ed. Kirk-Othmer encyclopedia of chemical technology. 4th ed. New York, John Wiley & Sons, vol 17, pp 133-152.
8. Adler A (1934) Pallidar syndrome with hyperkinesis and "Zwangsdenken" as sequelae of nitro-benzene poisoning. Z Gesamte Neurol Psychiat, 150: 341-345 [cited in Von Oettingen, 1941].
9. Adler B, Braun R, Schoeneich J, & Boehme H (1976) Repair-defective mutants of Proteus mirabilis as a prescreening system for the detection of potential carcinogens. Biol Zentralbl, 95: 463 [cited in Beauchamp et al., 1982].
10. Albert RE (1994) Carcinogen risk assessment in the U.S. Environment Protection Agency. Crit Rev Toxicol, 24: 75-85.
11. Albrecht W & Neumann H-G (1985) Biomonitoring of aniline and nitrobenzene: Hemoglobin binding in rats and analysis of adducts. Arch Toxicol, 57: 1-5.
12. Aldenberg T (1993) ETX 1.3a. A program to calculate confidence limits for hazardous concentrations based on small samples of toxicity data. Bilthoven, National Institute of Public Health and Environmental Protection (No. 719102015).
13. Aldenberg T & Slob W (1993) Confidence limits for hazardous concentrations based on logistically distributed NOEC toxicity data. Ecotoxicol Environ Saf, 25: 48-63.
14. Alexander M & Lustigman BK (1966) Effect of chemical structure on microbial degradation of substituted benzenes. J Agric Food Chem, 14: 410-413.
15. Allenby G, Sharpe RM, & Foster PM (1990) Changes in Sertoli cell function in vitro induced by nitrobenzene. Fundam Appl Toxicol, 14: 364-375.
16. Allenby G, Foster PM, & Sharpe RM (1991) Evaluation of changes in the secretion of immunoactive inhibin by adult rat seminiferous tubules in vitro as an indicator of early toxicant action on spermatogenesis. Fundam Appl Toxicol, 16: 710-724.
17. Altschuh J, Brüggemann R, Santl H, Eichinger G, & Piringer OG (1999) Henry's law constants for a diverse set of organic chemicals: Experimental determination and comparison of estimation methods. Chemosphere, 39: 1871-1887.
18. Amacher DE, Paillet SC, Tumer GN, Ray VA, & Salsburg DS (1980) Point mutations at the thymidine kinase locus in L5178Y mouse lymphoma cells. II. Test validation and interpretation. Mutat Res, 72: 447-474.
19. Amoore JE & Hautala E (1983) Odor as an aid to chemical safety: Odor thresholds compared with threshold limit values and volatilities for 214 industrial chemicals in air and water dilution. J Appl Toxicol, 3: 272-290.
20. Anbar M & Neta P (1967) A compilation of specific bimolecular rate constants for the reactions of hydrated electrons, hydrogen atoms and hydroxyl radicals with inorganic and organic compounds in aqueous solution. Int J Appl Radiat Isot, 18: 493-523.
21. Anderson D & Styles JA (1978) The bacterial mutation test. Br J Cancer, 37: 924-930.
22. Anderson EL (1983) Quantitative approaches in use to assess cancer risk. Risk Anal, 3: 277-295.
23. Anderson GE (1983) Human exposure to atmospheric concentrations of selected chemicals. Vol II. Research Triangle Park, North Carolina, US Environmental Protection Agency, Office of Air Quality Planning and Standards (NTIS No. PB83-265249).
24. Anderson TA, Beauchamp JJ, & Walton BT (1991) Organic chemicals in the environment. Fate of volatile and semivolatile organic chemicals in soils: abiotic versus biotic losses. J Environ Qual, 20: 420-424.
25. Anonymous (1987) Chemical profiles: Nitrobenzene. Chemical Marketing Reporter, 3 August, p 50.
26. ANZECC/ARMCANZ (2000) Australian and New Zealand guidelines for fresh and marine water quality. National Water Quality Management Strategy, Australian and New Zealand Environment Conservation Council and Agriculture and Resource Management Council of Australia and New Zealand (further information can be found at http://www.environment.gov.au/water/quality/).
27. Arinç E & Aydoǧmus A (1990) Lung microsomal p-nitrophenol hydroxylase - characterization and reconstitution of its activity. Comp Biochem Physiol B, 97: 455-460.
28. Amts RR, Seila RL, & Bufalini JJ (1987) Determination of OH rate constants for six volatile organics in air using the UCR protocol. Washington, DC, US Environmental Protection Agency (Report No. EPA-600/D-87-197).
29. Aßmann N, Emmrich M, Kampf G, & Kaiser M (1997) Genotoxic activity of important nitrobenzenes and nitroanilines in the Ames test and their structure-activity relationship. Mutat Res, 395: 139-144.
30. Astier A (1992) Simultaneous high-performance liquid chromatographic determination of urinary metabolites of benzene, nitrobenzene, toluene, xylene and styrene. J Chromatogr, 573: 318-322.
31. Atkinson R (1985) Kinetics and mechanisms of the gas-phase reactions of the hydroxyl radical with organic compounds under atmospheric conditions. Chem Rev, 85: 69-201.
32. Atkinson R (1990) Lifetimes and fates of toxic air contaminants in California's atmosphere. Riverside, California, University of California, Statewide Air Pollution Research Centre (Report ARB-R-90/441).
33. Atkinson R, Tuazon EC, Wellington TJ, Aschmann SM, Arey J, Winer AM, & Pitts JN Jr (1987) Atmospheric chemistry of aniline, N,N-dimethylaniline, pyridine, 1,3,5-triazine and nitrobenzene. Environ Sci Technol, 21: 64-72.
34. ATSDR (1990) Toxicological profile for nitrobenzene. Atlanta, Georgia, US Department of Health and Human Services, Public Health Service, Agency for Toxic Substances and Disease Registry (Publication No. TP-90-19).
35. Bader M, Goen T, Muller J, & Angerer J (1998) Analysis of nitroaromatic compounds in urine by gas chromatography-mass spectrometry for the biological monitoring of explosives. J Chromatogr B, Biomed Sci Appl, 710(1-2): 91-99.
36. Bahnick DA & Doucette WJ (1988) Use of molecular connectivity indices to estimate soil sorption coefficients for organic chemicals. Chemosphere, 17: 1703-1715.
37. Baider LM & Isichenko TS (1990) [EPR studies and the role of the electron structure of the heterocycle in the metabolic denitrosation of 5-nitrofuran.] Izv Akad Nauk SSSR Biol, 6: 925-928 (in Russian).
38. x-air system. Chem Soc Jpn, 58: 2531-2540.
39. Banerjee S, Yalkowsky SH, & Valvani SC (1980) Water solubility and octanol/water partition coefficients of organics. Limitation of the solubility-partition coefficient correlation. Environ Sci Technol, 14: 1227-1229.
40. Bangert S, McDonald DB, Prior SJ Jr, & Tuthill SJ (1988) Manufactured gas waste disposal investigations. Two case studies in Iowa. In: Proceedings of the 42nd Industrial Waste Conference, 12-14 May 1987. Boca Raton, Florida, Lewis Publishers, pp 39-51.
41. Barth EF & Bunch RL (1979) Removability, biodegradation and treatability of specific pollutants. Washington, DC, US Environmental Protection Agency (Report No. EPA-600/9-79-034; NTIS No. PB80-106-438).
42. Bartsch H, Malaveille C, Camus AM, Martel-Planche G, Brun G, Hautefeuille A, Sabadie N, Barbin A, Kuroki T, Drevon C, Piccoli C, & Montesano R (1980) Validation and comparative studies on 180 chemicals with S. typhimurium strains and V79 Chinese hamster cells in the presence of various metabolizing systems. Mutat Res, 76: 1-50.
43. BASF (1977) Bericht über die Prüfung der akuten Inhalationsgefahr von Nitrobenzol an der Ratte. Ludwigshafen, BASF Aktiengesellschaft (unpublished).
44. BASF (1997) Investigation of the potential for DNA binding of nitrobenzene. Ludwigshafen, BASF Aktiengesellschaft (unpublished).
45. BASF, Bayer, & Zeneca (1995) Cytogenic study in vivo of nitrobenzene in mice, micronucleus test, single intraperitoneal administration (unpublished report).
46. Beard RR & Noe JT (1981) Aromatic nitro and amino compounds. In: Clayton GD & Clayton FE ed. Patty's industrial hygiene and toxicology, 3rd ed. Vol 2A: Toxicology. New York, John Wiley & Sons, pp 2416-2417, 2430-2434, 2469, 2484-2489.
47. Beauchamp ROJ, Irons RD, Rickert DE, Couch DB, & Hamm TEJ (1982) A critical review of the literature on nitrobenzene toxicity. CRC Crit Rev Toxicol, 11: 33-84.
48. Benkendorf C (1978) Metabolic pathways of the N-substituted naphthalenes: their relationship to mutagenicity and carcinogenicity. Diss Abstr Int, B39: 2723-B.
49. Berger J (1990) Bone marrow and spleen morphology following haemolytic anaemia in adult laboratory rats of various age groups. Folia Haematol Int Mag Klin Morphol Blutforsch, 117: 1-5.
50. Billings RE (1985) Mechanisms of catechol formation from aromatic compounds in isolated rat hepatocytes. Drug Metab Dispos, 13: 287-290.
51. Bio/dynamics Inc. (1983) A range-finding study to evaluate the toxicity of nitrobenzene in the pregnant rabbit. East Millstone, New Jersey, Bio/dynamics Inc. (Project No. 83-2723; unpublished).
52. Bio/dynamics Inc. (1984) An inhalation teratology study in rabbits with nitrobenzene. Conducted for the Nitrobenzene Association Toxicology Task Group. East Millstone, New Jersey, Bio/dynamics Inc., 16 August (Project No. 83-2725; unpublished).
53. Blaauboer BJ & Van Holsteijn CW (1983) Formation and disposition of N-hydroxylated metabolites of aniline and nitrobenzene by isolated rat hepatocytes. Xenobiotica, 13: 295-302.
54. Black JA, Birge WJ, McDonnell WE, Westerman AG, Ramey BA, & Bruser DM (1982) The aquatic toxicity of organic compounds to embryo-larval stages of fish and amphibians. Lexington, Kentucky, University of Kentucky, Water Resources Research Institute (Research Report No. 133; NTIS No. PB82-224601).
55. Blum DJ & Speece RE (1991) A database of chemical toxicity to environmental bacteria and its use in interspecies comparisons and correlations. J Water Pollut Control Fed, 63: 198-207.
56. Bollman MA, Wanda KB, Smith S, DeWhitt K, & Kapustka L (1990) Report on algal toxicity tests on selected Office of Toxic Substances (OTS) chemicals. Corvallis, Oregon, US
57. Environmental Protection Agency, pp 1-42 (Report No. EPA/600/3-90/041; NTIS No. PB-90-212606).
58. Bond JA, Chism JP, Rickert DE, & Popp JA (1981) Induction of hepatic and testicular lesions in Fischer-344 rats by single oral doses of nitrobenzene. Fundam Appl Toxicol, 1: 389-394.
59. Borghoff SJ (1999) Male rat renal carcinogens: Distinguishing the contribution of the a2u globulin-mediated mechanism. CIIT Activ, 19(10): 5-6.
60. Bozzelli JW & Kebbekus BB (1982) A study of some aromatic and halocarbon vapors in the ambient atmosphere of New Jersey. J Environ Sci Health, A17: 693-711.
61. Bozzelli JW, Kebbekus BB, & Greenberg A (1980) Analysis of selected toxic and carcinogenic substances in ambient air at New Jersey. Trenton, New Jersey, New Jersey Department of Environmental Protection, Office of Cancer and Toxic Substances Research.
62. Briggs GG (1973) Proceedings of the 7th British Insecticides and Fungicides Conference, p 83.
63. Briggs GG (1981) Theoretical and experimental relationships between soil adsorption, octanol-water partition coefficients, water solubilities, bioconcentration factors, and the parachor. J Agric Food Chem, 29: 1050-1059.
64. Bringmann G & Kühn R (1959) Vergleichende wasser-toxicologische Untersuchungen an Bakterien, Algen und Kleinkrebsen. Gesundheits-Ingenieur, 4: 115-120.
65. Bringmann G & Kühn R (1978) Grenzwerte der Schadwirkung wassergefahrdender Stoffe gegen Blaualgen (Microcystis aeruginosa) und Grunalgen (Scenedesmus quadricauda) im Zellvermehrungshemmtest. Vom Wasser, 80: 45-60.
66. Bringmann G & Kühn R (1980) Comparison of the toxicity thresholds of water pollutants to bacteria, algae, and protozoa in the cell multiplication inhibition test. Water Res, 14: 231-241.
67. Bringmann G & Kühn R (1982) Results of toxic action of water pollutants on Daphnia magna Straus tested by an improved standardized procedure. Z Wasser Abwasser Forsch, 15: 1-6.
68. Bryant C & DeLuca M (1991) Purification and characterization of an oxygen-insensitive NAD(P)H nitroreductase from Enterobacter cloacae. J Biol Chem, 266: 4119-4125.
69. BUA (1993) 2-Nitrophenol and 4-nitrophenol. GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance. Stuttgart, S. Hirzel Wissenscaftliche Verlagsgesellschaft, 168 pp (English translation of BUA Report 75, published in 1992).
70. BUA (1994) Nitrobenzene. GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance. Stuttgart, S. Hirzel Wissenscaftliche Verlagsgesellschaft, 100 pp (English translation of BUA Report 59, published in 1991).
71. BUA (1995) OH-radicals in the troposphere: Concentration and effects. GDCh-Advisory Committee on Existing Chemicals of Environmental Relevance. Stuttgart, S. Hirzel Wissen-scaftliche Verlagsgesellschaft, 163 pp (English translation of BUA Report 100, published in 1993).
72. Buccafusco RJ, Ells SJ, & LeBlanc GA (1981) Acute toxicity of priority pollutants to bluegill (Lepomis macrochirus). Bull Environ Contam Toxicol, 26: 446-452.
73. Bums & Roe (1982) Fate of priority pollutants in publicly owned treatment works. Vol 1. Paramas, New Jersey, Bums and Roe Industrial Services Organization; Washington, DC, US Environmental Protection Agency (Report No. EPA-440/1-82/303).
74. 1 mice. Drug Chem Toxicol, 17: 271-315.
75. Bums LH, Cline DM, & Lassiter RR (1982) Exposure analysis model system (EXAMS). Athens, Georgia, US Environmental Protection Agency, Environmental Research Laboratory (Report No. EPA-600/3-82-023).
76. Bus JS (1983) Aniline and nitrobenzene: Erythrocyte and spleen toxicity. CIIT Activ, 3(12): 1, 6.
77. Bus JS & Gibson JE (1982) Mechanisms of superoxide radical-mediated toxicity. J Toxicol Clin Toxicol, 19(6-7): 689-697.
78. Butterworth BE, Smith-Oliver T, Earle L, Loury DJ, White RD, Doolittle DJ, Working PK, Cattley RC, Jirtle R, Michalopoulos G, & Strom S (1989) Use of primary cultures of human hepatocytes in toxicology studies. Cancer Res, 49: 1075-1084.
79. Callahan MA, Slimak MW, Gabel NW, May IP, Fowler CF, Freed JR, Jennings P, Durfee RL, Whitmore FC, Maestri B, Mabey WR, Holt BR, & Gould C (1979) Water-related environmental fate of 129 priority pollutants. Vol II. Washington, DC, US Environmental Protection Agency, Office of Water Planning and Standards (Report No. EPA-440/4-79-029b; NTIS No. PB80-204381).
80. Camara E, Leder AE, & Ishikawa Y (1997) CEH data summary: Nitrobenzene. In: Chemical economics handbook. Menlo Park, California, SRI International.
81. Canton JH, Slooff W, Kool HJ, Struys J, Pouw TJM, Wegman RCC, & Piet GJ (1985) Toxicity, biodegradability and accumulation of a number of C1/N containing compounds for classification and establishing water quality criteria. Regul Toxicol Pharmacol, 5: 123-131.
82. Carter FW (1936) An unusual case of poisoning, with some notes on non-alkaloidal organic substances. Med J Aust, 24: 558-564.
83. Caspary WJ, Daston DS, Myhr BC, Mitchell AD, Rudd CJ, & Lee PS (1988) Evaluation of the L5178Y mouse lymphoma cell mutagenesis assay: Interlaboratory reproducibility and assessment. Environ Mol Mutagen, 12(Suppl 13): 195-229.
84. 1 mice and F344 and CD rats. Fundam Appl Toxicol, 22: 328-340.
85. Cerutti PA (1994) Oxy-radicals and cancer. Lancet, 344: 862-863.
86. Chambers JV & O'Neill FJ (1945) Nitrobenzene poisoning; report of a fatal case. US Navy Med Bull (Washington), 44: 1112-1115.
87. Chapman PM, Fairbrother A, & Brown D (1998) A critical evaluation of safety (uncertainty) factors for ecological risk assessment. Environ Toxicol Chem, 17: 99-108.
88. Chapman WM & Fox CG (1945) Nitrobenzene poisoning from furniture cream. Br Med J, i: 557.
89. Charde VN, Keskar JB, Ingle AO, Parhad NM, & Daginawala HE (1990) Biodegradation of nitrobenzene by mixed bacterial culture systems. Asian Environ, 12: 41.
90. Chiu CW, Lee LH, Wang CY, & Bryan GT (1978) Mutagenicity of some commercially available nitro compounds for Salmonella typhimurium. Mutat Res, 58: 11-22.
91. Chou WL, Speece RE, & Siddiqi RH (1978) Acclimation and degradation of petrochemical wastewater components by methane fermentation. Biotechnol Bioeng Symp, 8: 391-414.
92. Chrastil J & Wilson TJ (1975) 4-Nitrocatechol production from p-nitrophenol by rat liver. J Pharmacol Exp Ther, 193: 631-638.
93. 1 mice, Fischer 344 rats and Sprague-Dawley (CD) rats. Vols I & II. Research Triangle Park, North Carolina, Chemical Industry Institute of Toxicology, 20 January 1993 (unpublished).
94. CLPSD (1988) Contract Laboratory Program Statistical Database. Alexandria, Virginia, Viar and Co., Management Services Division, December 1988.
95. Cole RH, Frederick RE, Healy RP, & Rolan RG (1984) Preliminary findings of the priority pollutant monitoring project of the nationwide urban runoff program. J Water Pollut Control Fed, 56: 898-908.
96. Collins JV, Mayo DR, & Riordan BJ (1982) Economic impact analysis of proposed test rule for nitrobenzene. Washington, DC, US Environmental Protection Agency, Office of Pesticides and Toxic Substances.
97. Corbett MD & Chipko BR (1977) N-Phenylglycolhydroxamate production by action of transketolase on nitrosobenzene. Biochem J, 165(2): 263-267.
98. Crebelli R, Conti L, Carere A, Bertoli C, & Del Gicomo N (1995) The effect of fuel composition on the mutagenicity of diesel engine exhaust. Mutat Res, 346: 167-172.
99. Crookes MJ, Quarterman P, Howe P, & Dobson S (1994) Environmental hazard assessment: Nitrobenzene. Garston, Watford, United Kingdom Building Research Establishment & Institute of Terrestrial Ecology (Document No. BRE 125/4/32).
100. Crump KS (1984) A new method for determining allowable daily intakes. Fundam Appl Toxicol, 4(5): 854-871.
101. Crump KS (1996) The linearized multistage model and the future of quantitative risk assessment. Hum Exp Toxicol, 15: 787-798.
102. Crump KS, Guess HA, & Deal KL (1977) Confidence intervals and test of hypotheses concerning dose response relations inferred from animal carcinogenicity data. Biometrics, 33: 437-451.
103. Cunningham ML & Ringrose PS (1983) Benzo(a)pyrene and aniline increase sister chromatid exchanges in cultured rat liver fibre-blasts without addition of activating enzymes. Toxicol Lett, 16: 235-239.
104. Cupitt LT (1980) Fate of toxic and hazardous materials in the air environment. Washington, DC, US Environmental Protection Agency (Report No. EPA-600/3-80-084; NTIS No. PB80-221948).
105. Daly J, Jerina D, & Witkop B (1968) Migration of deuterium during hydroxylation of aromatic substrates by liver microsomes. 1. Influence of ring substituents. Arch Biochem Biophys, 128: 517-527.
106. Dana MT, Lee RN, & Hales JM (1984) Hazardous air pollutants: Wet removal rates and mechanisms. Research Triangle Park, North Carolina, US Environmental Protection Agency (Report No. EPA-600/3-84-113).
107. David A, Sroba J, & Hykes P (1965) Biochemische Befunde bei der akuten Vergiftung mit Nitrobenzol bei Menschen. Folia Haemat (Leipzig), 83: 532-538.
108. Davis EM, Murray HE, Liehr JG, & Powers EL (1981) Basic microbial degradation rates and chemical byproducts of selected organic compounds. Water Res, 15: 1125-1127.
109. Davis EM, Turley JE, Casserly DM, & Guthrie RK (1983) Partitioning of selected organic pollutants in aquatic ecosystems. Biodeterioration, 5: 176-184.
110. De Bruin A (1976) Biochemical toxicology of environmental agents. New York, Elsevier/North Holland Inc.
111. 1 mice and characterization of N-(deoxyguanosin-8-yl)-4-aminoazobenzene as the major persistent hepatic DNA-bound dye in these mice. Cancer Res, 44: 2540-2550.
112. Dellarco VL & Prival MJ (1989) Mutagenicity of nitro compounds in Salmonella typhimurium in the presence of flavin mononucleotide in a preincubation assay. Environ Mol Mutagen, 13: 116-127.
113. DeMarini DM, Shelton ML, & Bell DA (1996) Mutation spectra of chemical fractions of a complex mixture: role of nitroarenes in the mutagenic specificity of municipal waste incinerator emissions. Mutat Res, 349: 1-20.
114. Deneer JW, Sinnige TL, Seinen W, & Hermens JLM (1987) Quantitative structure-activity relationships for the toxicity and bioconcentration factor of nitrobenzene derivatives towards the guppy (Poecilia reticulata). Aquat Toxicol, 10: 115-129.
115. Deneer JW, van Leeuwen CJ, Seinen W, Maas-Diepeveen JL, & Hermens JLM (1989) QSAR study of the toxicity and bioconcentration factor of nitrobenzene derivatives towards Daphnia magna, Chlorella pyrenoidosa and Photobacterium phosphoreum. Aquat Toxicol, 15: 83-98.
116. Denga N, Moldeus P, Kasilo OM, & Nhachi CFB (1995) Use of urinary p-nitrophenol as an index of exposure to parathion. Bull Environ Contam Toxicol, 55: 296-302.
117. Dennis RM, Wujeik WJ, Lowe WL, & Marks PJ (1990) Task Order 7. Use of activated carbon for treatment of explosive-contaminated groundwater at the Milan army ammunition plant. Aberdeen Proving Ground, Maryland, US Army Toxic and Hazardous Materials Agency (Report CETHA-TE-CR-90041).
118. DFG (1995) MAK and BAT values 1995. Deutsche Forschungsgemeinschaft. Weinheim, VCH Verlagsgesellschaft, pp 49, 145 (Report No. 31).
119. Dietrich DR & Swenberg JA (1991) NCI-Black-Reiter (NBR) male rats fail to develop renal disease following exposure to agents that induce alpha-2u-globulin (alpha 2u) nephropathy. Fundam Appl Toxicol, 16: 749-762.
120. Dodd AH (1891) Poisoning by nitro-benzole: Recovery. Br Med J, i: 849-850.
121. Dodd DE, Fowler EH, Snellings WM, Pritts IM, Tyl RW, Lyon JP, O'Neal FO, & Kimmerle G (1987) Reproduction and fertility evaluations in CD rats following nitrobenzene inhalation. Fundam Appl Toxicol, 8: 493-505.
122. Dorfman LE & Adams GE (1973) Reactivity of the hydroxyl radical in aqueous solution. Washington, DC, US Department of Commerce, National Bureau of Standards (Report NSRD-NDM-46).
123. Dorigan J & Hushon J (1976) Air pollution assessment of nitrobenzene. McLean, Virginia, The Mitre Corporation (NTIS No. PB257-776).
124. Downs TJ, Cifuentes-Garcia E, & Suffet IM (1999) Risk screening for exposure to groundwater pollution in a wastewater irrigation district of the Mexico City region. Environ Health Perspect, 107: 553-561.
125. Draper WM & Crosby DG (1984) Solar photooxidation of pesticides in dilute hydrogen peroxide. J Agric Food Chem, 32: 231-237.
126. Dreher D & Junod AF (1996) Role of oxygen free radicals in cancer development. Eur J Cancer, 32A: 30-38.
127. Dukes MNG ed. (1992) Meyler's side effects of drugs. An encyclopedia of adverse reactions and interactions, 12th ed. London, Elsevier.
128. Dunkel VC, Pienta R, Sivak A, & Traul KA (1981) Comparative neoplastic transformation responses of Balb/3T3 cells, Syrian hamster embryo cells, and Rauscher murine leukemia virus-infected Fischer 344 rat embryo cells to chemical carcinogens. J Natl Cancer Inst, 67: 1303-1315.
129. Dunlap KL (1981) Nitrobenzenes and nitrotoluenes. In: Mark HF, Othmer DF, Overberger CG, Seaborg GT, & Grayson N ed. Kirk-Othmer encyclopedia of chemical technology, vol 15. New York, John Wiley and Sons, pp 916-932.
130. Dunnivant FM, Schwarzenbach RP, & Macalady DL (1992) Reduction of substituted nitrobenzene in aqueous solutions containing natural organic matter. Environ Sci Technol, 26: 2133-2141.
131. ECDIN (2000) Environmental Chemicals Data and Information Network. Environmental Research Program, Joint Research Centre, Commission of European Communities.
132. Ellenhom MJ & Barceloux DG (1988) Medical toxicology: Diagnosis and treatment of human poisoning. New York, Elsevier, p 848.
133. Ellis DD, Jones CM, Larson RA, & Schaeffer DJ (1982) Organic constituents of mutagenic secondary effluents from wastewater treatment plants. Arch Environ Contam Toxicol, 11: 373-382.
134. Enfield CG, Walters DM, Wilson JT, & Piwoni MD (1986) Behavior of organic pollutants during rapid-infiltration of wastewater into soil: II. Mathematical description of transport and transformation. Hazard Waste Hazard Mater, 3: 57-76.
135. Environment Agency Japan (1992) [Chemicals in the environment. Report on environmental survey and wildlife monitoring of chemicals in fiscal year 1991.] Tokyo, Environment Agency Japan, Department of Environmental Health (in Japanese).
136. EU (2001) European Union risk assessment report. CAS-No.: 62-53-3, EINECS-No.: 200-539-3. Aniline. Draft. 28 May 2001. Luxembourg, Office for Official Publications of the European Communities.
137. Ewert R, Buttgereit F, Prugel M, & Reinke P (1998) Intravenous injection of India ink with suicidal intent. Int J Legal Med, 111: 91-92.
138. Eyer P (1979) Reactions of nitrosobenzene with reduced glutathione. Chem Biol Interact, 24: 227-239.
139. Eyer P & Ascherl M (1987) Reactions of para-substituted nitrosoamines with human hemoglobin. Biol Chem Hoppe-Seyler, 368: 285-294.
140. Eyer P & Lierheimer E (1980) Biotransformation of nitrobenzene in the red blood cell and the role of glutathione. Xenobiotica, 10: 517-526.
141. Eyer P, Kampffmeyer H, Maister H, & Rösch-Oehme E (1980) Biotransformation of nitrosobenzene, phenylhydroxylamine, and aniline in the isolated perfused rat liver. Xenobiotica, 10: 499-516.
142. Fairbanks VF & Klee GG (1986) Biochemical aspects of hematology. In: Tietz NW ed. Textbook of clinical chemistry. Philadelphia, Pennsylvania, W.B. Saunders, pp 1536-1540.
143. Feig DI, Reid TM, & Loeb LA (1994) Reactive oxygen species in tumorigenesis. Cancer Res, 54: 1890s-1894s.
144. Feldmann RJ & Maibach HI (1970) Absorption of some organic compounds through the skin in man. J Invest Dermatol, 54: 399-404.
145. Fielding M, Gibson TM, James HA, McLoughlin K, & Steel CP (1981) Organic micro-pollutants in drinking water. Medmenham, Water Research Centre (Technical Report TR159).
146. Fischbach F (1996) A manual of laboratory & diagnostic tests, 5th ed. Philadelphia, Pennsylvania, Lippincott-Raven Publishers.
147. Fletcher JS, McFarlane JC, Pfleeger T, & Wickliff C (1990) Influence of root exposure concentration on the fate of nitrobenzene in soybean. Chemosphere, 20: 513-523.
148. Flohé L, Beckmann R, Giertz H, & Loschen G (1985) Oxygen-centered free radicals as mediators of inflammation. In: Sies H ed. Oxidative stress. New York, Academic Press, pp 403-435.
149. Flury F & Zemik F (1931) Schädlicke Gase. [Noxious gases.] Berlin, J. Springer [cited in Von Oettingen, 1941].
150. Fouts JR & Brodie BB (1957) The enzymatic reduction of chloramphenicol, p-nitrobenzoic acid and other nitroaromatic compounds in mammals. J Pharmacol Exp Ther, 119: 197-207.
151. Freitag D, Geyer H, Kraus A, Viswanathan R, Kotzias D, Attar A, Klein W,
152. 14C-labelled chemicals. Chemosphere, 14: 1589-1616.
153. Fullerton WW (1930) Two rather uncommon fatal cases of poisoning. 1. Nitrobenzene poisoning - suicidal. 2. Sodium fluoride poisoning - accidental. New Engl J Med, 203: 423.
154. Galloway SM, Armstrong MJ, Reuben C, Colman S, Brown B, Cannon C, Bloom AD, Nakamura F, Ahmed M, Duk S, Rimpo J, Margolin BH, Resnick MA, Anderson B, & Zeiger E (1987) Chromosome aberrations and sister chromatid exchanges in Chinese hamster ovary cells: Evaluations of 108 chemicals. Environ Mol Mutagen, 10 (Suppl 10): 1-175.
155. Gamer RC & Nutman CA (1977) Testing of some azo dyes and their reduction products for mutagenicity using Salmonella typhimurium TA 1538. Mutat Res, 44: 9-19.
156. Gaylor DW (1989) Preliminary estimates of the virtually safe dose for tumors obtained from the maximum tolerated dose. Regul Toxicol Pharmacol, 9: 101-108.
157. Gaylor DW (1992) Relationship between the shape of dose-response curves and background tumor rates. Regul Toxicol Pharmacol, 16: 2-9.
158. Gaylor DW & Gold LS (1995) Quick estimate of the regulatory virtually safe dose based on the maximum tolerated dose for rodent bioassays. Regul Toxicol Pharmacol, 22: 57-63.
159. Gaylor DW & Gold LS (1998) Regulatory cancer risk assessment based on the quick estimate of a benchmark dose derived from the maximum tolerated dose. Regul Toxicol Pharmacol, 28: 222-225.
160. Geiger DL, Northcott CE, Call DJ, & Brooke LT (1985) Acute toxicities of organic chemicals to fathead minnows (Pimephales promelas). Vol 2. Superior, Wisconsin, University of Wisconsin-Superior, Center for Lake Superior Environmental Studies.
161. Gershon H, McNeil MW, Parmegiani R, & Godfrey PK (1971) Antifungal activity of substituted nitrobenzenes and anilines. Appl Microbiol, 22: 438-440.
162. Gerstle RW (1988) Emissions of trace metals and organic compounds from sewage sludge incineration. In: Proceedings of the 81st Air Pollution Control Association Annual Meeting, Vol 5 (Paper 88/95B.6).
163. Gerstle R & Carvitti J (1987) Sludge incineration and hazardous air pollutants. Sludge Manage Ser, 17: 169-174.
164. Geyer H, Viswanathan R, Freitag D, & Korte F (1981) Relationship between water solubility of organic chemicals and their bioaccumulation by the alga Chlorella. Chemosphere, 10: 1307-1313.
165. Geyer H, Politzki G, & Freitag D (1984) Prediction of ecotoxicological behaviour of chemicals: relationship between n-octanol/water partition coefficient and bioaccumulation of organic chemicals by alga Chlorella. Chemosphere, 13: 269-284.
166. Gholson AR, Albritton JR, Jayanty RKM, Knoll JE, & Midgett MR (1991) Evaluation of an enclosure method for measuring emissions of volatile organic compounds from quiescent liquid surfaces. Environ Sci Technol, 25: 519-524.
167. Gianti SJ, Harkov R, & Bozzelli JW (1984) Monitoring volatile organic compounds at hazardous and sanitary landfills in New Jersey. In: Proceedings of the 77th Air Pollution Control Association Annual Meeting, San Francisco, California, 24-29 June 1984, Vol 1 (Paper 84-3.7).
168. Gilbert P, Rondelet J, Poncelet F, & Mercier M (1980) Mutagenicity of p-nitrosophenol. Food Cosmet Toxicol, 18: 523-525.
169. Goldstein A, Aronow L, & Kalman SM (1969) Principles of drug action: The basis of pharmacology. New York, Harper and Row Publishers, pp 274-452.
170. Goldstein I & Popovici C (1960) Modifications de la catalase et de la péroxidase dans l'intoxication expérimentale au nitrobenzene. Med Lav, 51: 42-48.
171. 14C]nitrobenzene in the erythrocyte and spleen of rats and mice. Chem Biol Interact, 50: 27-37.
172. Goldstein RS & Rickert DE (1985) Relationship between red blood cell uptake and methemoglobin production by nitrobenzene and dinitrobenzene in vitro. Life Sci, 36: 121-125.
173. Goldstein RS, Dyroff MC, Rickert DE, & Hamm TE (1983a) Characterization of covalent binding of orally administered nitrobenzene to erythrocytic macromolecules. Pharmacologist, 25: 116(Abstr. 78).
174. Goldstein RS, Irons RD, & Rickert DE (1983b) Pathophysiology of splenic toxicity in mice and rats following oral nitrobenzene (NB) administration. Toxicologist, 3: 125 (Abstr).
175. Goldstein RS, Chism JP, & Hamm TJ (1984a) Influence of diet on intestinal microfloral metabolism and toxicity of nitrobenzene. Toxicologist, 4: 143 (Abstr).
176. Goldstein RS, Chism JP, Sherrill JM, & Hamm TE (1984b) Influence of dietary pectin on intestinal microfloral metabolism and toxicity of nitrobenzene. Toxicol Appl Pharmacol, 75: 547-553.
177. Gomółka B & Gomółka E (1983) Degradation of benzene derivatives in aerated municipal wastewater. Arch Ochr Srodowiska, 3/4: 113-123.
178. Gomółka E & Gomółka B (1979) Ability of activated sludge to degrade nitrobenzene in municipal wastewater. Acta Hydrochim Hydrobiol, 7: 605-622.
179. Gosselin RE, Smith RP, Hodge HC, & Braddock JE (1984) Clinical toxicology of commercial products, 5th ed. Baltimore, Maryland, Williams & Wilkins, pp II-214, III-31-III-36.
180. Govind R, Flaherty PA, & Dobbs RA (1991) Fate and effects of semivolatile organic pollutants during anaerobic digestion of sludge. Water Res, 25: 547-556.
181. Grafe E & Homburger A (1914) Industrial nitro-benzene poisoning with Korsakow syndrome, followed by mental debility. Z Gesamte Neurol Psychiat, 25: 343 [cited in Nabarro, 1948].
182. Guess H & Crump K (1976) Low-dose extrapolation of data from animal carcinogenesis experiments - analysis of a new statistical technique. Math Biosci, 32: 15-36.
183. Guicherit R & Schulting FL (1985) The occurrence of organic chemicals in the atmosphere of the Netherlands. Sci Total Environ, 43: 193-219.
184. Gutteridge JMC (1995) Lipid peroxidation and antioxidants as biomarkers for tissue damage. Clin Chem, 41: 1819-1828.
185. Guyton KZ & Kensler TW (1993) Oxidative mechanisms in carcinogenesis. Br Med Bull, 49: 523-544.
186. Haderlein SB & Schwarzenbach RP (1993) Adsorption of substituted nitrobenzenes and nitrophenols to mineral surfaces. Environ Sci Technol, 27: 316-326.
187. Haigler BE & Spain JC (1991) Biotransformation of nitrobenzene by bacteria containing toluene degradative pathways. Appl Environ Microbiol, 57: 3156-3162.
188. Hain Z, Dalmacija B, Miskovic D, & Karlovic E (1990) Preparation of drinking water from the surface water of the Danube - A case study. Water Sci Technol, 22: 253-258.
189. Hall LW Jr, Hall WS, Bushong SJ, & Herman RL (1987) In situ striped bass (Morone saxatilis) contaminant and water quality studies in the Potomac River. Aquat Toxicol, 10: 73-99.
190. Hallas LE & Alexander M (1983) Microbial transformation of nitroaromatic compounds in sewage effluent. Appl Environ Microbiol, 45: 1234-1241.
191. 1 mice. Research Triangle Park, North Carolina, Chemical Industry Institute of Toxicology (unpublished).
192. 1 mice. Toxicologist, 4: 181 (Abstr).
193. Hard GC, Rodgers IS, Baetcke KP, Richards WL, McGaughy KP, & Valcovic LP (1993) Hazard evaluation of chemicals that cause accumulation of alpha-2u-globulin, hyaline droplet nephropathy and tubule neoplasia in the kidneys of male rats. Environ Health Perspect, 99: 313-349.
194. Hargesheimer EE & Lewis CM (1987) Comparative source water quality monitoring at two surface reservoirs. In: Proceedings of the Annual Conference of the American Water Works Association, Denver, Colorado, pp 153-175.
195. Harkov R, Kebbekus B, Bozzelli JW, & Lioy PJ (1983) Measurement of selected volatile organic compounds at three locations in New Jersey during the summer season. J Air Pollut Control Assoc, 33: 1177-1183.
196. Harkov R, Kebbekus B, Bozzelli JW, Lioy PJ, & Daisey J (1984) Comparison of selected volatile organic compounds during the summer and winter at urban sites in New Jersey. Sci Total Environ, 38: 259-274.
197. Harkov R, Gianti SJ Jr, Bozzelli JW, & LaRegina JE (1985) Monitoring volatile organic compounds at hazardous and sanitary landfills in New Jersey. J Environ Sci Health, A20: 491-501.
198. Harmer D, Taylor MJ, Woollen BH, & Loftus MJ (1989) The biological monitoring of workers exposed to nitrobenzene. In: Grandjean EC ed. Occupational health in the chemical industry. XVI Medichem Congress, Helsinki, Finland, 27-30 September 1988. Copenhagen, WHO Regional Office for Europe, pp 142-146.
199. Harrison MR (1977) Toxic methaemoglobinaemia. A case of acute nitrobenzene and aniline poisoning treated by exchange transfusion. Anaesthesia, 32: 270-272.
200. Harton E & Rawl RR (1976) Toxicological and skin corrosion testing of selected hazardous materials. Final report 1973-1974. US Department of Transportation, Office of Hazardous Materials Operations, April (Report No. DOT/MTB/OHMO-76/2; NTIS No. PB-264 975).
201. Haseman JK & Lockhart A (1994) The relationship between use of the maximum tolerated dose and study sensitivity for detecting rodent carcinogenicity. Fundam Appl Toxicol, 22(3): 382-391.
202. Hastings SH & Matsen FA (1948) The photodecomposition of nitrobenzene. J Am Chem Soc, 70: 3514-3515.
203. Hattori M, Senoo K, Harada S, Ishizu Y, & Goto M (1984) [The Daphnia reproduction test of some environmental chemicals.] Seital Kagaku, 6: 23-27 (in Japanese).
204. Haworth S, Lawlor T, Mortelmans K, Speck W, & Zeiger E (1983) Salmonella mutagenicity test results for 250 chemicals. Environ Mutagen, 5 (Suppl 1): 3-38, 46, 114.
205. Hazleton Laboratories (1982) Final report: 104 week chronic toxicity study in rats. Aniline hydrochloride. Vienna, Virginia, Hazleton Laboratories America Inc. [summary of study reprinted in CIIT Activ, 3(9): 3-4, September 1983].
206. Hazleton Laboratories (1982) Final report: 104 week chronic toxicity study in rats. Aniline hydrochloride. Vienna, Virginia, Hazleton Laboratories America Inc. [summary of study reprinted in CIIT Activ, 3(9): 3-4, September 1983].
207. Hecht SS (1996) Recent studies on mechanisms of bioactivation and detoxification of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK), a tobacco-specific lung carcinogen. CRC Crit Rev Toxicol, 26: 163-181.
208. Hecht SS, El-Bayoumy K, Rivenson A, & Fiala ES (1983) Bioassay for carcinogenicity of 3,2′-dimethyl-4-nitrosobiphenyl, o-nitrosotoluene, nitrosobenzene and the corresponding amines in Syrian golden hamsters. Cancer Lett, 20: 349-354.
209. Hecht SS, Carmella SG, Foiles PG, & Murphy SE (1994) Biomarkers for human uptake and metabolic activation of tobacco-specific nitrosamines. Cancer Res, 54: 1912s-1917s.
210. Hedgecott S & Rogers HR (1991) Freshwater quality. Additional reports undertaken for the Royal Commission on Environmental Pollution. London, HMSO (Report No. CO 2672-M/1).
211. Heim de Balsac F, Agasse-Lafonte E, & Feil SA (1930) [Professional nitrobenzene poisoning.] Prog Med, 45: 817-821 (in French).
212. Hein DW (1988) Acetylator phenotype and arylamine-induced carcinogenesis. Biochem Biophys Acta, 948: 37-66.
213. Hein DW, Doll MA, Fretland AJ, Gray K, Deitz AC, Feng Y, Jiang W, Rustan TD, Satran SL, & Wilkie TR Sr (1997) Rodent models of the human acetylation polymorphism: comparisons of recombinant acetyltransferases. Mutat Res, 376: 101-106.
214. Heitmuller PT, Hollister TA, & Parrish PR (1981) Acute toxicity of 54 industrial chemicals to sheepshead minnows (Cyprinodon variegatus). Bull Environ Contam Toxicol, 27: 596-604.
215. Helling CS & Turner BC (1968) Pesticide mobility: Determination by soil thin-layer chromatography. Science, 162: 562-563.
216. Helmig D, Muller J, & Klein W (1989) Volatile organic substances in a forest atmosphere. Chemosphere, 19: 1399-1412.
217. Hendry DG & Kenley RA (1979) Atmospheric reaction products of organic compounds. Washington, DC, US Environmental Protection Agency (Report No. EPA-560/12-79-001).
218. Heukelekian H & Rand MC (1955) Biochemical oxygen demand of pure organic compounds. J Water Pollut Control Assoc, 27: 1040-1053.
219. Ho CH, Clark BR, & Guerin MR (1981) Analytical and biological analyses of test materials from the synthetic fuel technologies: IV. Studies of chemical structure-mutagenic activity relationships of aromatic nitrogen compounds relevant to synfuels. Mutat Res, 85: 335-345.
220. Hogarth CW (1912) A case of poisoning by oil of mirbane (nitro-benzol). Br Med J, i: 183.
221. Holcombe GW, Phipps GL, Knuth ML, & Felhaber T (1984) The acute toxicity of selected substituted phenols, benzenes and benzoic acid esters to fathead minnows (Pimephales promelas). Environ Pollut Ser A, 35: 367-381.
222. Holder JW (1998) Nitrobenzene carcinogenicity (CAS No. 98-95-3). Washington, DC, US Environmental Protection Agency, National Center for Environment Assessment (Control No. EPA/600/R-95/100; available for downloading from http://www.epa.gov/ncea or hard copy from the National Technical Information Service, Springfield, Virginia, PB98-143282).
223. Holder JW (1999a) Nitrobenzene carcinogenicity in animals and human hazard evaluation. Toxicol Ind Health, 15: 445-457.
224. Holder JW (1999b) Nitrobenzene potential human cancer risk based on animal studies. Toxicol Ind Health, 15: 458-463.
225. Hoshino M, Akimoto H, & Okuda M (1978) Photochemical oxidation of benzene, toluene and ethylbenzene initiated by OH radicals in the gas phase. Bull Chem Soc Jpn, 51: 718-724.
226. Howard PH, Boethling RS, Jarvis WF, Meylan WM, & Michalenko EM (1990) Handbook of environmental fate and exposure data for organic chemicals. Chelsea, Michigan, Lewis Publishers.
227. HSDB (1988) Hazardous substances data bank. Bethesda, Maryland, National Library of Medicine, National Toxicology Information Program.
228. Huang Q-G, Kong L-R, Liu Y-B, & Wang L-S (1996) Relationship between molecular structure and chromosomal aberrations in in vitro human lymphocytes induced by substituted nitrobenzenes. Bull Environ Contam Toxicol, 57: 349-353.
229. Hughes TJ, Sparacino C, & Frazier S (1984) Validation of chemicals and biological techniques for evaluation of vapors in ambient air/mutagenicity testing of twelve (12) vapor-phase compounds. Research Triangle Park, North Carolina, US Environmental Protection Agency (Report No. EPA 600/1-84-005; NTIS No. PB84-164-219).
230. Hunt WF Jr, Faoro RB, & Freas W (1986) Report on the interim database for state and local air toxic volatile organic chemical measurements. Washington, DC, US Environmental Protection Agency (Report No. EPA-450/4-86-012).
231. Hurley R & Testa AC (1966) Photochemical n → π* excitation of nitrobenzene. J Am Chem Soc, 88: 4330-4332.
232. Hurley R & Testa AC (1967) Nitrobenzene photochemistry 2. Protonation in excited state. J Am Chem Soc, 89(26): 6917-6919.
233. IARC (1982) Aniline. In: Some aromatic amines, anthraquinones and nitroso compounds, and inorganic fluorides used in drinking water and dental preparations. Lyon, International Agency for Research on Cancer (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol 27).
234. IARC (1996) Nitrobenzene. In: Printing processes and printing inks, carbon black and some nitro compounds. Lyon, International Agency for Research on Cancer (IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, Vol 65).
235. IARC (1999) Species differences in thyroid, kidney and urinary bladder carcinogenesis. Lyon, International Agency for Research on Cancer (IARC Scientific Publications No. 147).
236. Iida S, Misaka H, & Naya M (1997) A flow cytometric analysis of cytotoxic effects of nitrobenzene on rat spermatogenesis. J Toxicol Sci, 22: 397-407.
237. Ikeda M & Kita A (1964) Excretion of p-nitrophenol and p-aminophenol in the urine of a patient exposed to nitrobenzene. Br J Ind Med, 21: 210-213.
238. Ince N (1992) A theoretical approach to determination of evaporative rates and half lives of some priority pollutants in two major lakes of Istanbul. Int J Environ Studies, 40: 1-12.
239. IPCS (1994) Assessing human health risks of chemicals: derivation of guidance values for health-based exposure limits. Geneva, World Health Organization, International Programme on Chemical Safety (Environmental Health Criteria 170).
240. IPCS (2000) Mononitrophenols. Geneva, World Health Organization, International Programme on Chemical Safety (Concise International Chemical Assessment Document No. 20).
241. Jacobs LW, O'Connor GA, Overcash MA, Zabik MJ, Rygiewicz P, Machno P, Munger S, & Elseewi AA (1987) Effects of trace organics in sewage sludges on soil-plant systems and assessing their risk to humans. In: Land application of sludges: Food chain implications. Chelsea, Michigan, Lewis Publishers.
242. Jeng CY, Chan DH, & Yaws CL (1992) Data compilation for soil sorption coefficient. Pollut Eng, 24: 54-60.
243. Juhnke I & Lüdemann D (1978) Results of research on acute fish toxicity of 200 chemical compounds using golden orfe test. Z Wasser Abwasser Forsch, 11: 161-164.
244. Jury WA, Spencer WF, & Farmer WJ (1984) Behavior asessment model for trace organics in soil: III. Application of screening model. J Environ Qual, 13: 573-579.
245. Kadlubar FF & Ziegler DM (1974) Properties of a NADH-dependent N-hydroxy amine reductase isolated from pig liver microsomes. Arch Biochem Biophys, 162: 83-92.
246. Kaiser KLE & Palabrica VS (1991) Photobacterium phosphoreum toxicity data index. Water Pollut Res J Can, 26: 361-431.
247. Kaiser KLE & Ribo JM (1985) QSAR of toxicity of chlorinated aromatic compounds. In: Tichy M ed. QSAR in toxicology and xenobiochemistry. Amsterdam, Elsevier, pp 27-38.
248. Kalf GF, Post GB, & Snyder R (1987) Solvent toxicology: Recent advances in the toxicology of benzene, the glycol ethers, and carbon tetrachloride. Annu Rev Pharmacol Toxicol, 27: 399-427.
249. Kato M, Kimura H, Hayashi H, Tobe K, Shimizu M, Ota T, & Furuhashi T (1995) Sperm viability in rats treated with nitrobenzene and alpha-chlorohydrin. Teratology, 52: P-57 (Abstr).
250. Kawai A, Goto S, Matsumoto Y, & Matsushita H (1987) [Mutagenicity of aliphatic and aromatic nitro compounds.] Jpn J Ind Health, 29: 34-54 (in Japanese with an English abstract).
251. Kawashima K, Momma J, Takagi A, Katajima S, & Kurokawa Y (1995a) Examination of sperm motility defects by nitrobenzene with an image processor. Teratology, 52: P-27 (Abstr).
252. Kawashima K, Usami M, Sakemi K, & Ohno Y (1995b) Studies on the establishment of appropriate spermatogenic endpoints for male infertility disturbance in rodent induced by drugs and chemicals. I. Nitrobenzene. J Toxicol Sci, 20: 15-22.
253. Keher JP (1993) Free radicals as mediators of tissue injury and disease. CRC Crit Rev Toxicol, 23: 21-48.
254. Kenley RA, Davenport JE, & Hendry DG (1981) Gas-phase hydroxyl radical reactions. Products and pathways for the reaction of OH with aromatic hydrocarbons. J Phys Chem, 85: 2740-2746.
255. Kensler TW, Egner PA, Taffe BG, & Trush MA (1989) Role of free radicals in tumor promotion and progression. Prog Clin Biol Res, 298: 233-248.
256. Khan MF, Boor PJ, Gu Y, Alcock NW, & Ansari GA (1997) Oxidative stress in the splenotoxicity of aniline. Fundam Appl Toxicol, 35: 22-30.
257. Kiese M (1966) The biochemical production of ferrihemoglobin forming derivatives from aromatic amines and mechanisms of ferrihemoglobin formation. Pharmacol Rev, 18: 1091-1161.
258. Kiese M (1974) Methemoglobinemia: A comprehensive treatise. Cleveland, Ohio, CRC Press.
259. Kincannon DF & Lin YS (1985) Microbial degradation of hazardous wastes by land treatment. In: Bell JM ed. Proceedings of the 40th Industrial Waste Conference. Boston, Massachusetts, Butterworth-Heinemann, pp 607-619.
260. King CM, Romano JL, & Schuetzle D ed. (1988) Carcinogenic and mutagenic responses to aromatic amines and nitroamines. New York, Elsevier Publishing Co.
261. Klaassen CD ed. (2001) Casarett & Doull's toxicology: the basic science of poisons, 6th ed. New York, McGraw-Hill.
262. Kligerman AD, Erexson GL, Wilmer JL, & Phelps MC (1983) Analysis of cytogenetic damage in rat lymphocytes following in vivo exposure to nitrobenzene. Toxicol Lett, 18: 219-226.
263. Koch R & Nagel M (1988) Quantitative structure activity relationships in soil ecotoxicology. Sci Total Environ, 77: 269-276.
264. Kodama M, Kaneko M, Aida M, Inoue F, Nakayama T, & Akimoto H (1997) Free radical chemistry of cigarette smoke and its implication in human cancer. Anticancer Res, 17: 433-437.
265. Kopfler FC, Melton RG, Mullaney JL, & Tardiff RG (1977) Human exposure to water pollutants. Adv Environ Sci Technol, 8: 419-433.
266. Korte F & Klein W (1982) Degradation of benzene in the environment. Ecotoxicol Environ Saf, 6: 311-327.
267. Krewski D, Gaylor DW, Soms AP, & Szyszkowicz M (1993) An overview of the report - correlation between carcinogenic potency and the maximum tolerated dose - implications for risk assessment. Risk Anal, 13(4): 383-398.
268. Kubota Y (1979) Experience with the chemical substances control law in Japan. Ecotoxicol Environ Saf, 3: 256-268.
269. Kühn R, Pattard M, Pernak KD, & Winter A (1989) Results of the harmful effects of water pollutants to Daphnia magna in the 21 day reproduction test. Water Res, 23: 501-510.
270. Kuhn W & Clifford D (1986) Experience with specific organic analyses for water quality control in West Germany. In: Proceedings of the 13th American Water Works Association Water Quality Technology Conference. Denver, Colorado, American Water Works Association, pp 353-363.
271. Kumar A, Chawla R, Ahuja S, Girdhar KK, & Bhattacharya A (1990) Nitrobenzene poisoning and spurious pulse oximetry. Anaesthesia, 45: 949-951.
272. Kuroda Y (1986) Genetic and chemical factors affecting chemical mutagenesis in cultured mammalian cells. In: Shankel DM, Hartman PE, Kada T, Hollaender A, Wilson CM, & Kuny G ed. Antimutagenesis and anticarcinogenesis mechanisms. New York, Plenum Press, pp 359-375.
273. Laramée JA, Kocher CA, & Deinzer ML (1992) Application of a trochoidal electron monochromator/mass spectrometer system to the study of environmental chemicals. Anal Chem, 64: 2316-2322.
274. LaRegina J, Bozzelli JW, Harkov R, & Gianti S (1986) Volatile organic compounds at hazardous waste sites and a sanitary landfill in New Jersey. Environ Prog, 5: 18-27.
275. Lauwerys RR (1991) Occupational toxicology. In: Amdur MO, Doull J, & Klaassen CD ed. Casarett & Doull's toxicology - The basic science of poisons, 4th ed. New York, Pergamon Press, pp 947-969.
276. Leader SD (1932) Nitrobenzene poisoning: Report of an unusual case in a child. Arch Pediatr, 49: 245-250.
277. LeBlanc GA (1980) Acute toxicity of priority pollutants to water flea (Daphnia magna). Bull Environ Contam Toxicol, 24: 684-691.
278. Levin AA & Dent JG (1982) Comparison of the metabolism of nitrobenzene by hepatic microsomes and cecal microflora from Fischer-344 rats in vitro and the relative importance of each in vivo. Drug Metab Dispos, 10: 450-454.
279. Levin AA, Bus JS, & Dent JG (1982) Interactions of nitrobenzene with hepatic microsomes. Evidence for cytochrome P-450 uncoupling. Toxicologist, 2: 17.
280. Levin AA, Bosakowski T, Earle LL, & Butterworth BE (1988) The reversibility of nitrobenzene-induced testicular toxicity: continuous monitoring of sperm output from vasocystotomized rats. Toxicology, 53: 219-230.
281. Levins P, Adams J, Brenner P, Coons S, & Harris G (1979) Sources of toxic pollutants found in influents to sewerage treatment plants. Boston, Massachusetts, AD Little Inc. (ADL 81099-63).
282. Lewalter J & Ellrich D (1991) Nitroaromatic compounds (nitrobenzene, p-nitrotoluene, p-nitrochlorobenzene, 2,6-dinitrotoluene, o-dinitrobenzene, 1-nitronaphthalene, 2-nitronaphthalene, 4-nitrobiphenyl). Anal Hazard Subst Biol Mater, 3: 207-215.
283. Liepins R, Mixon F, Hudak C, & Parsons TB (1977) Industrial process profiles for environmental use. Chapter 6. The industrial organic chemicals industry. Washington, DC, US Environmental Protection Agency (Report No. EPA-600/2-77/023F).
284. Linch AL (1974) Biological monitoring for industrial exposure to cyanogenic aromatic nitro and amino compounds. Am Ind Hyg Assoc J, 35: 426-432.
285. Under RE, Strader LF, Slott VL, & Suarez JD (1992) Endpoints of spermatotoxicity in the rat after short duration exposures to fourteen reproductive toxicants. Reprod Toxicol, 6: 491-505.
286. Lioy PJ, Daisey JM, Atherholt T, Bozzelli J, Darack R, Fisher R, Greenberg A, Harkov R, Kebbekus B, Kneip TJ, Lewis J, McGarrity G, McGeorge L, & Reiss NM (1983) The New Jersey Project on airborne toxic elements and organic substances (ATEOS): A summary of the 1981 summer and 1982 winter studies. J Air Pollut Control Fed, 33: 649-657.
287. Locket S (1957) Clinical toxicology. London, Henry Kimpton, pp 505-506.
288. Løkke H (1984) Sorption of selected organic pollutants in Danish soils. Ecotoxicol Environ Saf, 8: 395-409.
289. Lu PY & Metcalf RL (1975) Environmental fate and biodegradabiliry of benzene derivatives as studied in a model aquatic ecosystem. Environ Health Perspect, 10: 269-284.
290. Luke JSH & Betton GR (1987) In vitro evaluation of haemic systems in toxicology. In: Atterwill CK & Steele CE ed. In vitro methods in toxicology. Cambridge, Cambridge University Press.
291. Lutin PA, Cibulka JJ, & Malaney GW (1965) Oxidation of selected carcinogenic compounds by activated sludge. Purdue Univ Eng Ext Ser, 118: 131-145.
292. Lyman WJ, Reehl WF, & Rosenblatt DH (1982) Handbook of chemical property estimation methods. New York, McGraw-Hill Book Co., p 960.
293. Maas-Diepeveen JL & Van Leeuwen CJ (1986) [Aquatic toxicity of aromatic nitro compounds and anilines to several freshwater species.] Arnhem, Institute for Inland Water Management and Waste Water Treatment, Laboratory for Ecotoxicology, 10 pp (Report No. 86-42) (in Dutch).
294. Mabey WR, Smith JH, Podoll RT, Johnson HL, Mill T, Chou T-W, Gates J, Waight Partridge I, Jaber H, & Vandenberg D (1982) Aquatic fate process data for organic priority pollutants. Washington, DC, US Environmental Protection Agency, Office of Water Regulations and Standards (Report No. EPA 440/4-81-014; NTIS No. PB87-169090/XAB).
295. Mallevialle J, Bruchet A, & Schmitt E (1984) Nitrogenous organic compounds: Identification and significance in several French water treatment plants. In: Proceedings of the 11th American Water Works Association Water Quality Technology Conference, pp 83-96.
296. Manufacturing Chemists Association (1968) Research on chemical odors. Part 1. Odor thresholds for 53 commercial chemicals. Washington, DC, Manufacturing Chemists Association, October 1968, p 23.
297. Maples KR, Eyer P, & Mason RP (1990) Aniline-, phenylhydroxylamine-, nitrosobenzene-, and nitrobenzene-induced hemoglobin thiyl free radical formation in vivo and in vitro. Mol Pharmacol, 37: 311-318.
298. Marchini S, Tosato ML, Norberg-King TJ, Hammermeister DE, & Hoglund MD (1992) Lethal and sublethal toxicity of benzene derivatives to the fathead minnow, using a short term test. Environ Toxicol Chem, 11: 187-195.
299. Marchini S, Hoglund MD, Broderius SJ, & Tosato ML (1993) Comparison of the susceptibility of daphnids and fish to benzene derivatives. In: Proceedings of the 2nd European Conference on Ecotoxicology, Recent Advances in Toxicology, 11-15 May 1992, pp. 799-808. Sci Total Environ Suppl 1993, Part 1.
300. Marion CV & Malaney GW (1963) Ability of activated sludge microorganisms to oxidize aromatic organic compounds. Purdue Univ Eng Ext Ser, 115: 297-308.
301. Maser E (1997) Stress, hormonal changes, alcohol, food constituents and drugs: factors that advance the incidence of tobacco smoke-related cancer? Trends Pharmacol Sci, 18: 270-275.
302. Mason RP (1982) Free-radical intermediates in the metabolism of toxic chemicals. In: Pryor WA ed. Free radicals in biology, Vol V. New York, Academic Press, pp 161-222.
303. Mason RP & Holtzman JL (1975a) The mechanism of microsomal and mitochondrial nitroreductase. Electron spin resonance evidence for nitroaromatic free radical intermediates. Biochemistry, 14: 1626-1632.
304. 2 inhibition of nitroreductase. Biochem Biophys Res Commun, 67: 1267-1274.
305. Matsumaru H & Yoshida T (1959) Experimental studies of nitrobenzol poisoning. Kyushu J Med Sci, 10: 259-264.
306. McCann J, Choi E, Yamasaki E, & Ames BN (1975) Detection of carcinogens as mutagens in the Salmonella/microsome test; assay of 300 chemicals. Proc Natl Acad Sci USA, 12: 5135.
307. McCrady JK, McFarlane C, & Lindstrom FT (1987) The transport and affinity of substituted benzenes in soybean stems. J Exp Bot, 38: 1875-1890.
308. McFarlane C, Nolt C, Wickliff C, Pfleeger T, Shimabuku R, & McDowell M (1987a) The uptake, distribution and metabolism of four organic chemicals by soybean plants and barley roots. Environ Toxicol Chem, 6: 847-856.
309. McFarlane JC, Pfleeger T, & Fletcher J (1987b) Transpiration effect on the uptake and distribution of bromacil, nitrobenzene and phenol in soybean plants. J Environ Qual, 16: 372-376.
310. McLaren TT, Foster PM, & Sharpe RM (1993a) Effect of age on seminiferous tubule protein secretion and the adverse effects of testicular toxicants in the rat. Int J Androl, 16: 370-379.
311. McLaren TT, Foster PM, & Sharpe RM (1993b) Identification of stage-specific changes in protein secretion by isolated seminiferous tubules from the rat following exposure to either m-dinitrobenzene or nitrobenzene. Fundam Appl Toxicol, 21: 384-392.
312. Medinsky MA & Irons RD (1985) Sex, strain and species differences in the response of rodents to nitrobenzene vapours. Toxicity of nitroaromatic compounds. New York, Hemisphere Publishing Corporation.
313. Meijers AP & Van Der Leer RC (1976) The occurrence of organic micropollutants in the River Rhine and the River Maas in 1974. Water Res, 10: 597-604.
314. Miller JA (1970) Carcinogenesis by chemicals: an overview - G.H.A. Clowes memorial lecture. Cancer Res, 30: 559-576.
315. Mirsalis JC, Tyson CK, & Butterworth BE (1982) Detection of genotoxic carcinogens in the in vivo-in vitro hepatocyte DNA repair essay. Environ Mutagen, 4: 553-562.
316. MITI (1992) Biodegradation and bioaccumulation data of existing chemicals based on the CSCL Japan. Tokyo, Ministry of International Trade & Industry, Japan Chemicals Inspection & Testing Institute, Japan Chemical Industry Ecology-Toxicology & Information Center.
317. Mitsumori K, Kodama Y, Uchida O, Takada K, Saito M, Naito K, Tanaka S, Kurokawa Y, Usami M, Kawashima K, Yasuhara K, Toyoda K, Onodera H, Furukawa F, Takahashi M, & Hayashi Y (1994) Confirmation study, using nitrobenzene, of the combined repeat dose and reproductive/developmental toxicity test protocol proposed by the Organisation for Economic Cooperation and Development (OECD). J Toxicol Sci, 19: 141-149.
318. Moeschlin S (1965) Poisoning: Diagnosis and treatment, 1st US ed. New York, Grune & Stratton, pp 362-366.
319. Morgan KT, Gross EA, Lyght O, & Bond JA (1985) Morphologic and biochemical studies of a nitrobenzene-induced encephalopathy in rats. Neurotoxicology, 6: 105-116.
320. Morrissey RE, Schwetz BA, Lamb JC, Ross MD, Teague JL, & Morris RW (1988) Evaluation of rodent sperm, vaginal cytology, and reproductive organ weight data from National Toxicology Program 13 week studies. Fundam Appl Toxicol, 11: 343-358.
321. Muehlberger CW (1925) Shoe dye poisoning. J Am Med Assoc, 84: 1987-1991.
322. Myslak Z, Piotrowski JK, & Musialowicz E (1971) Acute nitrobenzene poisoning: A case report with data on urinary excretion of p-nitrophenol and p-aminophenol. Arch Toxikol, 28: 208-213.
323. Nabarro JD (1948) A case of acute mononitrobenzene poisoning. Br Med J, 15: 929-931.
324. Narayanan B, Suidan MT, Gelderloos AB, & Brenner RC (1993) Treatment of semi-volatile compounds in high strength wastes using an anaerobic expanded-bed GAC reactor. Water Res, 27: 171-180.
325. Nelson CR & Hites RA (1980) Aromatic amines in and near the Buffalo River. Environ Sci Technol, 14: 1147-1149.
326. Netke SP, Roomi MW, Tsao C, & Niedzwiecki A (1997) Ascorbic acid protects guinea pigs from acute aflatoxin toxicity. Toxicol Appl Pharmacol, 143: 429-435.
327. Neuhauser EF, Loehr RC, Malecki MR, Milligan DL, & Durkin PR (1985) The toxicity of selected organic chemicals to the earthworm Eisenia fetida. J Environ Qual, 14: 383-388.
328. Neuhauser EF, Loehr RC, & Malecki MR (1986) Contact and artificial soil tests using earthworms to evaluate the impact of wastes in soil. In: Hazardous and industrial solid waste testing: Fourth symposium. Philadelphia, Pennsylvania, American Society for Testing and Materials, pp 192-203 (ASTM STP 886).
329. Neumann H-G (1984) Analysis of hemoglobin as a dose monitor for alkylating and arylating agents. Arch Toxicol, 56: 1-6.
330. Neumann H-G (1988) Biomonitoring of aromatic amines and alkylating agents by measuring haemoglobin adducts. Int Arch Occup Environ Health, 60: 151-155.
331. Nielsen IR, Diment J, & Dobson S (1993) Environmental hazard assessment: Aniline. Watford, Building Research Establishment (TSD/14).
332. NIOSH (1977) Nitrobenzene - method S217. In: NIOSH manual of analytical methods, Vol 3. Cincinnati, Ohio, National Institute of Occupational Safety and Health, pp S217-1-S217-9.
333. NIOSH (1984) Nitrobenzene - method 2005. In: NIOSH manual of analytical methods, 3rd ed. Cincinnati, Ohio, National Institute of Occupational Safety and Health, pp 2005-1-2005-5.
334. NIOSH (1990) National Occupational Exposure Survey (1981-1983). Cincinnati, Ohio, National Institute of Occupational Safety and Health (unpublished provisional data as of 7 January 1990).
335. Nishino SF & Spain JC (1993) Degradation of nitrobenzene by a Pseudomonas pseudoalcaligenes. Appl Environ Microbiol, 59: 2520-2525.
336. Nohmi T, Yoshikawa K, Nakadate M, Miyata R, & Ishidate M Jr (1984) Mutations in Salmonella typhimurium and inactivation of Bacillus subtilis transforming DNA induced by phenylhydroxylamine derivatives. Mutat Res, 136: 159-168.
337. Nojima K & Kanno S (1977) Studies on photochemistry of aromatic hydrocarbons. IV. Mechanism of formation of nitrophenols by the photochemical reaction of benzene and toluene with nitrogen oxides in air. Chemosphere, 6: 371-376.
338. Nolt CL (1988) Uptake and translocation of six organic chemicals in a newly-designed plant exposure system and evaluation of plant uptake aspects of the prebiologic screen for ecotoxicologic effects. MS Thesis. Ithaca, New York, Cornell University.
339. Noordsij A, Puyker LM, & Van Der Gaag MA (1985) The quality of drinking water prepared from bank-filtered river water in the Netherlands. Sci Total Environ, 47: 273-292.
340. Norambuena E, Videla LA, & Lissi EA (1994) Interaction of nitrobenzoates with haemoglobin in red blood cells and a haemolysate. Human Exp Toxicol, 13: 345-351.
341. 1 mice. Conducting Laboratory: EG & G Mason Research Institute. Reviewed by the Pathology Working Group, National Toxicology Program, Public Health Service, National Institutes of Health, 20 July 1983 (unpublished).
342. 1 mice. Conducting Laboratory: EG & G Mason Research Institute. Reviewed by the Pathology Working Group, National Toxicology Program, Public Health Service, National Institutes of Health, 15 July 1983 (unpublished).
343. OECD (1981) OECD guidelines for testing of chemicals. Paris, Organisation for Economic Co-operation and Development.
344. OECD (1992) Report of the OECD workshop on extrapolation of laboratory aquatic toxicity data to the real environment. Paris, Organisation for Economic Co-operation and Development (OECD Environment Monograph No. 59).
345. OECD (1995) Guidance document for aquatic effects assessment. Paris, Organisation for Economic Co-operation and Development (OECD Environment Monograph No. 92).
346. Ohkuma Y & Kawanishi S (1999) Oxidative DNA damage by a metabolite of carcinogenic and reproductive toxic nitrobenzene in the presence of NADH and Cu(II). Biochem Biophys Res Commun, 257: 555-560.
347. Ongley ED, Birkholz DA, Carey JH, & Samoiloff MR (1988) Is water a relevant sampling medium for toxic chemicals? An alternative environmental sensing strategy. J Environ Qual, 17: 391-401.
348. Otson R, Williams DT, & Bothwell PD (1982) Volatile organic compounds in water at thirty Canadian potable water treatment facilities. J Assoc Off Anal Chem, 65: 1370-1374.
349. Pacséri I, Magos L, & Bátskor IA (1958) Threshold and toxic limits of some amino and nitro compounds. Am Med Assoc Arch Ind Health, 18: 1-8.
350. 14C]nitrobenzene in the rabbit and guinea pig. Biochem J, 62: 339-346.
351. Parkes WE & Neill DW (1953) Acute nitrobenzene poisoning with transient amino-aciduria. Br Med J, i: 653-655.
352. Parodi S, Taningher M, Russo P, Pala M, Tamaro M, & Monti-Bragadin C (1981) DNA-damaging activity in vivo and bacterial mutagenicity of sixteen aromatic amines and azoderivatives, as related quantitatively to their carcinogenicity. Carcinogenesis, 2: 1317-1326.
353. Parodi S, Pala M, Russo P, Zunino A, Balbi C, Albini A, Valerio F, Cimberle MR, & Santi L (1982) DNA damage in liver, kidney, bone marrow, and spleen of rats and mice treated with commercial and purified aniline as determined by alkaline elution assay and sister chromatid exchange induction. Cancer Res, 42: 2277-2283.
354. Paul SF & Lonkar ST (1992) Thermal desorption-gas chromatography for the determination of benzene, aniline, nitrobenzene and chlorobenzene in workplace air. J Chromatogr, 600: 344-351 [ Published erratum appears in J Chromatogr, 625(2): 402, 1992] .
355. Paul SF & Lonkar ST (1992) Thermal desorption-gas chromatography for the determination of benzene, aniline, nitrobenzene and chlorobenzene in workplace air. J Chromatogr, 600: 344-351 [ Published erratum appears in J Chromatogr, 625(2): 402, 1992] .
356. Patil SS & Shinde VM (1988) Biodegradation studies of aniline and nitrobenzene in aniline plant waste water by gas chromatography. Environ Sci Technol, 22: 1160-1165.
357. Patil SS & Shinde VM (1989) Gas chromatographic studies on the biodegradation of nitrobenzene and 2,4-dinitrophenol in the nitrobenzene plant wastewater. Environ Pollut, 57: 235-250.
358. Pellizzari ED (1978) Quantification of chlorinated hydrocarbons in previously collected air samples. Research Triangle Park, North Carolina, US Environmental Protection Agency (Report No. EPA-450/3-78-112).
359. Pendergrass SM (1994) An approach to estimating workplace exposure to o-toluidine, aniline and nitrobenzene. Am Ind Hyg Assoc J, 55: 733-737.
360. Perry DL, Chuang CC, Jungclaus GA, & Wamer JS (1979) Identification of organic compounds in industrial effluent discharges. Athens, Georgia, US Environmental Protection Agency, Office of Research and Development (Report No. EPA-600/4-79-016; NTIS No. PB-294 794/3).
361. Peterson PJ, Mason RP, Hovsepian J, & Holtzman JL (1979) Oxygen-sensitive and -insensitive nitroreduction by Escherichia coli and rat hepatic microsomes. J Biol Chem, 254: 4009-4014.
362. Piet GJ, Morra CH, & De Kruijf HA (1981) The behavior of organic micropollutants during passage through the soil. Stud Environ Sci, 17: 557-564.
363. Piotrowski J (1967) Further investigations on the evaluation of exposure to nitrobenzene. Br J Ind Med, 24: 60-65.
364. Pitter P (1976) Determination of biological degradability of organic substances. Water Res, 10: 231-235.
365. Piwoni MD, Wilson JT, Walters DM, Wilson BH, & Enfield CG (1986) Behaviour of organic pollutants during rapid-infiltration of wastewater into soil: I. Processes, definition, and characterization using a microcosm. Hazard Waste Hazard Mater, 3: 43-55.
366. Pizzolatti MG & Yunes RA (1990) Azoxybenzene formation from nitrosobenzene and phenylhydroxylamine - a unified view of the catalysis and mechanisms of the reactions. J Chem Soc Perkin Trans, 2(5): 759-764.
367. Polson CJ & Tattersall RN (1969) Clinical toxicology, 2nd ed. Bath, Pitman Press.
368. Pope AA, Cruse PA, & Most CC (1988) Toxic air pollutant emission factors - A compilation for selected air toxic compounds and sources. Washington, DC, US Environmental Protection Agency (Report No. EPA-450/2-88-006A).
369. Price CJ, Tyl RW, Marks TA, Paschke LL, Ledoux TA, & Reel JR (1985) Teratologic and postnatal evaluation of aniline hydrochloride in the Fischer 344 rat. Toxicol Appl Pharmacol, 77: 465-478.
370. Probst GS, McMahon RE, Hill LE, Thompson CZ, Epp JK, & Neal SB (1981) Chemically-induced unscheduled DNA synthesis in primary rat hepatocyte cultures: A comparison with bacterial mutagenicity using 218 compounds. Environ Mutagen, 3: 11-32.
371. Pryor WA (1997) Cigarette smoke radicals and the role of free radicals in chemical carcinogenicity. Environ Health Perspect, 105: 875-882.
372. Purchase IFH, Longstaff E, Ashby J, Styles JA, Anderson D, Lefevre PA, & Westwood FR (1978) An evaluation of 6 short term tests for detecting organic chemical carcinogens. Br J Cancer, 37: 873-903.
373. Ramos EU, Vaes WHJ, Verhaar HJM, & Hermens JLM (1998) Quantitative structure-activity relationships for the aquatic toxicity of polar and nonpolar narcotic pollutants. J Chem Inf Comp Sci, 38(5): 845-852.
374. Ramos EU, Vaes WHJ, Mayer P, & Hermens JLM (1999) Algal growth inhibition of Chlorella pyrenoidosa by polar narcotic pollutants: toxic cell concentrations and QSAR modeling. Aquat Toxicol, 46(1): 1-10.
375. Ramsay DHE & Harvey CC (1959) Marking ink poisoning. An outbreak of methemoglobinemia cyanosis in newborn babies. Lancet, i: 910-912.
376. Rapoport IA (1965) Mutational effect of paranitroaceto-phenylene-tri- phenylphosphine in connection with the additivity of mutational tendencies. Presented by Academician N. N. Semenove, 21 August 1964. Translated from Doklady Akademii Nauk SSR, 60: 707-709.
377. Reddy BG, Pohl LR, & Krishna G (1976) The requirement of the gut flora in nitrobenzene-induced methemoglobinemia in rats. Biochem Pharmacol, 25: 1119-1122.
378. Rejsek K (1947) m-Dinitrobenzene poisoning. Mobilisation by alcohol and sunlight. Acta Med Scand, 127: 179-191.
379. Rickert DE (1984) Toxicity of nitroaromatic compounds. Washington, DC, Hemisphere Publishing Corp.
380. Rickert DE (1987) Metabolism of nitroaromatic compounds. Drug Metab Rev, 18: 23-53.
381. Rickert DE, Bond JA, Long RM, & Chism JP (1983) Metabolism and excretion of nitrobenzene by rats and mice. Toxicol Appl Pharmacol, 67: 206-214.
382. Robinson D, Smith JN, & Williams RT (1951) Studies in detoxication 40. The metabolism of nitrobenzene in the rabbit, o-, m- and p-nitrophenols, o-, m- and p-aminophenols and 4-nitrocatechol as metabolites of nitrobenzene. Biochem J, 50: 228-238.
383. Rogozen MB, Rich HE, Guttman MA, & Grosjean D (1987) Evaluation of potential toxic air contaminants. Phase 1. Final report. Sacramento, California, State of California Air Resources Board (Report ARB/R-88/333).
384. Romero IA, Ray DE, Chan MWK, & Abbott NJ (1996) An in vitro study of m-dinitrobenzene toxicity on the cellular components of the blood-brain barrier, astrocytes and endothelial cells. Toxicol Appl Pharmacol, 139: 94-101.
385. Rosen ME, Pankow JF, Gibs J, & Imbrigiotta TE (1992) Comparison of downhole and surface sampling for the determination of volatile organic compounds (VOCs) in ground water. Ground Water Monit Rev, 12: 126-133.
386. Rosenkranz HS (1996) Mutagenic nitroarenes, diesel emissions, particulate-induced mutations and cancer: an assay on cancer-causation by a moving target. Mutat Res, 367: 65-72.
387. Rosenkranz HS & Mermelstein R (1983) Mutagenicity and genotoxicity of nitroarenes. All nitro-containing chemicals were not created equal. Mutat Res, 114: 217-267.
388. Roy WR & Griffin RA (1985) Mobility of organic solvents in water-saturated soil materials. Environ Geol Water Sci, 7: 241-247.
389. Sabbioni G (1994) Hemoglobin binding of nitroarenes and quantitative structure-activity relationships. Chem Res Toxicol, 7: 267-274.
390. Salmowa J, Piotrowski J, & Neuhorn U (1963) Evaluation of exposure to nitrobenzene: Absorption of nitrobenzene vapour through lungs and excretion of p-nitrophenol in urine. Br J Ind Med, 20: 41-46.
391. Sanders FG (1920) Nitrobenzene poisoning with cyanosis: Report of case. J Am Med Assoc, 74: 1518-1519.
392. Schimelman MA, Soler JM, & Muller HA (1978) Methemoglobinemia: nitrobenzene ingestion. JACEP, J Am Coll Emerg Physicians, 7: 406-408.
393. Schmieder PK & Henry TR (1988) Plasma binding of 1-butanol, phenol, nitrobenzene and pentachlorophenol in the rainbow trout and rat: a comparative study. Comp Biochem Physiol, Part C, 91: 413-418.
394. Schroeder RE, Terrill JB, Lyon JP, Kaplan AM, & Kimmerle G (1986) An inhalation teratology study in the rabbit with nitrobenzene. Toxicologist, 6: 93 (Abstr).
395. Schultz TW, Dawson DA, & Lin DT (1989) Comparative toxicity of selected nitrogen-containing aromatic compounds in the Tetrahymena pyriformis and Pimephales promelas test systems. Chemosphere, 18: 2283-2291.
396. Schwarzenbach RP, Stierli R, Lanz K, & Zeyer J (1990) Quinone and iron porphyrin mediated reduction of nitroaromatic compounds in homogeneous aqueous solution. Environ Sci Technol, 24: 1566-1574.
397. Scott RW & Hanzlik PJ (1920) Poisoning by alcohol "denatured" with nitrobenzene. J Am Med Assoc, 10: 1000.
398. Sealy RC, Swartz HM, & Olive PL (1978) Electron spin resonance-spin trapping. Detection Of superoxide formation during aerobic microsomal reduction of nitro-compounds. Biochem Biophys Res Commun, 82: 680-684.
399. Seip HM, Alstad J, Carlberg GE, Martinsen K, & Skaane R (1986) Measurement of mobility of organic compounds in soils. Sci Total Environ, 50: 87-101.
400. Shackelford WM, Cline DM, Faas L, & Kurth G (1983) An evaluation of automated spectrum matching for survey identification of wastewater components by gas chromatography-mass spectrometry. Anal Chim Acta, 146: 15-27.
401. Shimizu M & Yano E (1986) Mutagenicity of mono-nitrobenzene derivatives in the Ames test and rec assay. Mutat Res, 170: 11-22.
402. Shimkin MB (1939) Acute toxicity of mononitrobenzene in mice. Proc Soc Exp Biol Med, 42: 844-846.
403. Shimo T, Onodera H, Matsushima Y, Todate A, Mitsumori K, Maekawa A, & Takahashi M (1994) [A 28-day repeated dose toxicity study of nitrobenzene in F344 rats.] Eisei Shikenjo Hokoku, 112: 71-81 (in Japanese with an English abstract).
404. Shinoda K, Mitsumori K, Yasuhara K, Ueyama C, Onodera H, Takegawa K, Takahashi M, & Umemura T (1998) Involvement of apoptosis in the rat germ cell degeneration induced by nitrobenzene. Arch Toxicol, 72: 296-302.
405. Simmons MS & Zepp RG (1986) Influence of humic substances on photolysis of nitroaromatic compounds in aqueous systems. Water Res, 20: 899-904.
406. 2). Taylor's principles and practice of medical jurisprudence, 12th ed. London, JA Churchill, vol 2, pp 441-443.
407. Smith RP, Alkaitis AA, & Shafer PR (1967) Chemically induced methemoglobinemias in the mouse. Biochem Pharmacol, 16: 317-328.
408. Smith RV & Rosazza JP (1974) Microbial models of mammalian metabolism. Aromatic hydroxylation. Arch Biochem Biophys, 161: 551-558.
409. Smith S & Fiddes FS (1955) Forensic medicine. London, Churchill.
410. Smyth HF, Weil CS, West JS, & Carpenter CP (1969) An exploration of joint toxic action: Twenty seven industrial chemicals intubated in rats in all possible pairs. Toxicol Appl Pharmacol, 14: 340-347.
411. Spicer CW, Riggin RM, Holdren MW, DeRoos FL, & Lee RN (1985) Atmospheric reaction products from hazardous air pollutant degradation. Washington, DC, US Environmental Protection Agency (Report No. EPA-600/3-85-028).
412. Spielmann H, Gemer I, Kalweit S, Moog R, Wirnsberger T, Krauser K, Kreiling R, Kreuzer H, Lüpke N-P, Miltenburger HG, Müller N, Mürmann P, Pape W, Siegemund B, Spengler J, Steiling W, & Wiebel FJ (1991) Intel-laboratory assessment of alternatives to the Draize eye irritation test in Germany. Toxic In Vitro, 5: 539-542.
413. Spinner JR (1917) Nitrobenzol not an abortifacient. J Am Med Assoc, 69: 2155.
414. SRI (1985) Directory of chemical producers. Western Europe. Menlo Park, California, SRI International.
415. Staples CA, Wemer AF, & Hoogheem TJ (1985) Assessment of priority pollutant concentrations in the United States using STORET database. Environ Toxicol Chem, 4: 131-142.
416. Staretz ME, Murphy SE, Patten CJ, & Nunes MG (1997) Comparative metabolism of the tobacco-related carcinogens benzo[a]pyrene, 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone, 4-(methylnitrosamino)-1-(3- pyridyl)-1-butanol and N-nitrosonomicotine in human hepatic microsomes. Drug Metab Dispos, 25: 154-162.
417. Stevens AM (1928) Cyanosis in infants from nitrobenzene. J Am Med Assoc, 90: 116.
418. Stier A, Clauss R, & Lücke A (1980) Redox cycle of stable mixed nitroxides formed from carcinogenic aromatic amines. Xenobiotica, 10: 661-673.
419. Stifel RE (1919) Methemoglobinemia due to poisoning by shoe dye: Report of a series of cases at an army camp. J Am Med Assoc, 72: 395-396.
420. Stolk JM & Smith RP (1966) Species differences in methemoglobin reductase activity. Biochem Pharmacol, 15: 343-351.
421. Stover EL & Kincannon DF (1983) Biological treatability of specific organic compounds found in chemical industry wastewaters. J Water Pollut Control Fed, 55: 97-109.
422. Styles JA (1978) Mammalian cell transformation in vitro. Br J Cancer, 37: 931-936.
423. Suzuki J, Koyama T, & Suzuki S (1983) Mutagenicities of mono-nitrobenzene derivatives in the presence of norharman. Mutat Res, 120: 105-110.
424. Suzuki J, Meguro S, Morita O, Hirayama S, & Suzuki S (1989) Comparison of in vivo binding of aromatic nitro and amino compounds to rat hemoglobin. Biochem Pharmacol, 38: 3511-3519.
425. Sziza M & Magos L (1959) Toxicologische Untersuchung einiger in der ungarischen Industrie zur Anwendung gelangenden aromatischen Nitroverbindungen. Arch Gewerbepathol Gewerbehyg, 17: 217-226.
426. Tabak HH, Quave SA, Mashni CI, & Barth EF (1981) Biodegradability studies with organic priority pollutant compounds. J Water Pollut Control Fed, 53: 1503-1518.
427. Thienes CH & Haley TJ (1955) Clinical toxicology, 3rd ed. London, Henry Kimpton, p 238.
428. Tonogai Y, Ogawa S, Ito Y, & Iwaida M (1982) Actual survey on TLm (median tolerance limit) values of environmental pollutants, especially on amines, nitrites, aromatic nitrogen compounds and artificial dyes. J Toxicol Sci, 7: 193-203.
429. Trabalka JR & Garten CT Jr (1982) Development of predictive models for xenobiotic bioaccumulation in terrestrial systems. Oak Ridge, Tennessee, Oak Ridge National Laboratory, Environmental Sciences Division, 249 pp (ORNL/TM-5869).
430. Trush MA & Kensler TW (1991) An overview of the relationship between oxidative stress and chemical carcinogenesis. Free Radical Biol Med, 10: 201-209.
431. Tumey GL & Goerlitz DF (1990) Organic contamination of groundwater at Gas Works Park, Seattle, Washington. Ground Water Monit Rev, 10: 187-198.
432. Tyl RW, France KA, Fisher LC, Dodd DE, Pritts IM, Lyon JP, O'Neal FO, & Kimmerle G (1987) Developmental toxicity evaluation of inhaled nitrobenzene in CD rats. Fundam Appl Toxicol, 8: 482-492.
433. Urano K & Kato Z (1986) Evaluation of biodegradation ranks of priority organic compounds. J Hazard Mater, 13: 147-159.
434. US EPA (1980) Ambient water quality criteria for nitrobenzene. Washington, DC, US Environmental Protection Agency (Report No. EPA 440/5-80-061; NTIS No. PB81-117723).
435. US EPA (1982a) Test method: Nitroaromatics and isophorone - method 609. In: Longbottom JE & Lichtenberg JJ ed. Test methods: Methods for organic chemical analysis of municipal and industrial wastewater. Washington, DC, US Environmental Protection Agency, Environmental Monitoring and Support Laboratory (Report No. EPA 600/4-82-057).
436. US EPA (1982b) Test method: Base/neutrals and acids - method 625. In: Longbottom JE & Lichtenberg JJ ed. Test methods: Methods for organic chemical analysis of municipal and industrial wastewater. Washington, DC, US Environmental Protection Agency, Environmental Monitoring and Support Laboratory (Report No. EPA 600/4-82-057).
437. US EPA (1983) Nitrobenzene. In: Treatability manual. Vol I. Treatability data. Washington, DC, US Environmental Protection Agency, Office of Research and Development (Report No. EPA-600/2-82-001a).
438. US EPA (1984) US Environmental Protection Agency. Fed Regist, 49: 25013-25017.
439. US EPA (1985) Health and environmental effects profile for nitrobenzene. Cincinnati, Ohio, US Environmental Protection Agency, Office of Research and Development (Report No. EPA 600/X-85/365; NTIS No. PB88-180500).
440. US EPA (1986a) Method 8410: Capillary column analysis of semivolatile organic compounds by gas chromatography/Fourier transform infrared (GC/FT-IR) spectrometry. In: Test methods for evaluating solid waste, 3rd ed. Washington, DC, US Environmental Protection Agency, Office of Solid Waste and Emergency Response (Report SW-846).
441. US EPA (1986b) Method 8090: Nitroaromatics and cyclic ketones. In: Test methods for evaluating solid waste, 3rd ed. Washington, DC, US Environmental Protection Agency, Office of Solid Waste and Emergency Response (Report SW-846).
442. US EPA (1986c) Method 8250: Gas chromatographic/mass spectrometry for semivolatile organics: Packed column technique. In: Test methods for evaluating solid waste, 3rd ed. Washington, DC, US Environmental Protection Agency, Office of Solid Waste and Emergency Response (Report SW-846).
443. US EPA (1986d) Method 8270: Gas chromatographic/mass spectrometry for semivolatile organics: Capillary column technique. In: Test methods for evaluating solid waste, 3rd ed. Washington, DC, US Environmental Protection Agency, Office of Solid Waste and Emergency Response (Report SW-846).
444. US EPA (1988) US Environmental Protection Agency: Part II. Fed Regist, 53: 31138-31222.
445. US EPA (1989) US Environmental Protection Agency: Part II. Fed Regist, 54: 1056-1119.
446. US EPA (1991) Alpha-2u-globulin: Association with chemically induced renal toxicity and neoplasia in the male rat. Washington, DC, US Environmental Protection Agency, Risk Assessment Forum (Report No. EPA/625/3-91/019F).
447. US EPA (1996) Proposed guidelines for cancer risk assessment. Fed Regist, 61: 17960-18011.
448. Vance WA & Levin DE (1984) Structural features of nitroaromatics that determine mutagenic activity in Salmonella typhimurium. Environ Mutagen, 6: 797-811.
449. Van Zoest R & Van Eck GTM (1991) Occurrence and behaviour of several groups of organic micropollutants in the Scheldt Estuary. Sci Total Environ, 103: 57-71.
450. Veith GD, DeFoe DL, & Bergstedt BV (1979) Measuring and estimating the bioconcentration factor of chemicals in fish. J Fish Res Board Can, 36: 1040-1048.
451. Vema L, Whysner J, & Williams GM (1996) 2-Acetylaminofluorene mechanistic data and risk assessment: DNA reactivity, enhanced cell proliferation and tumor initiation. Pharmacol Ther, 71: 83-105.
452. Verschueren K (1983) Handbook of environmental data on organic chemicals. New York, Van Nostrand Reinhold Company.
453. Volskay VT Jr & Grady CPL Jr (1988) Toxicity of selected RPA compounds to activated sludge microorganisms. J Water Pollut Control Fed, 60: 1850-1856.
454. Von Oettingen WF (1941) The aromatic amino and nitro compounds, their toxicity and potential dangers: A review of the literature. Washington, DC, US Public Health Service (Public Health Bulletin No. 271).
455. Waggot A & Wheatland AB (1978) Contribution of different sources to contamination of surface waters with specific persistent organic pollutants. In: Hutzinger O, Van Leylyveld IH, & Zoeteman BCJ ed. Aquatic pollutants: Transformation and biological effects. Proceedings of the 2nd International Symposium on Aquatic Pollutants, Noordwjjkerhout. Amsterdam, Pergamon Press.
456. Walterskirchen L (1939) Ein Fall von Mirbanölvergiftung. Wein Klin Wochenschr, 52: 317-318.
457. Walton BT, Hendricks MS, Anderson TA, & Talmage SS (1989) Treatability of hazardous Chemicals in soils: Volatile and semivolatile organics. Oak Ridge, Tennessee, Oak Ridge National Laboratory (US Department of Energy Contract AC05-840R21400; NTIS Order No. DE89016892/XAD).
458. Walton BT, Hendricks MS, Anderson TA, Griest WH, Merriweather R, Beauchamp JJ, & Francis CW (1992) Soil sorption of volatile and semivolatile organic compounds in a mixture. J Environ Qual, 21: 552-558.
459. Wang Y, Wang Z, Liu J, Ma M, & Belzile N (1999) Monitoring priority pollutants in the Yanghe River by dichlorometriane extraction and semipermeable membrane device (SPMD). Chemosphere, 39: 113-131.
460. Wangenheim J & Bolcsfoldi G (1988) Mouse lymphoma L5178Y thymidine kinase locus assay of 50 compounds. Mutagenesis, 3: 193-205.
461. Wame MS (1998) Critical review of methods to derive water quality guidelines for toxicants and a proposal for a new framework. Canberra, Environment Australia (Supervising Scientist Report 135).
462. Warner HP, Cohen JM, & Ireland JC (1987) Determination of Henry's law constants of selected priority pollutants. Washington, DC, US Environmental Protection Agency, pp 1-14 (Report No. EPA/600/D-87/229) [cited in BUA, 1994].
463. Weant GE & McCormick GS (1984) Nonindustrial sources of potentially toxic substances and their applicability to source apportionment methods. Washington, DC, US Environmental Protection Agency (Report No. EPA-450/4-84-003).
464. Webber MD & Lesage S (1989) Organic contaminants in Canadian municipal sludges. Waste Manage Res, 7: 63-82.
465. Weil C (1972) Statistics vs. safety factors and scientific judgment in the evaluation of safety for man. Toxicol Appl Pharmacol, 21: 454-463.
466. Weisberger JH & Weisberger EK (1973) Biochemical formation and pharmacological, toxicological, and pathological properties of hydroxylamines and hydroxamic acids. Pharmacol Rev, 25: 1-66.
467. Wellens H (1982) Vergleich der empfindlichkeit von Brachydario rerio und Leuciscus idus bei der Untersuchung der Fishtoxizitaet von chemischen Verbindungen und Abwassem. Wasser Abwasser Forsch, 15: 49-52.
468. Wheeler LA, Soderberg FB, & Goldman P (1975) The relationship between nitro group reduction and the intestinal microflora. J Pharmacol Exp Ther, 194: 135-144.
469. White RE (1980) Organic chemical manufacturing 1. Program. Washington, DC, US Environmental Protection Agency (Report No. EPA-450/3-80-023).
470. WHO (1986) Diseases caused by toxic nitro and amino derivatives of benzene and its homologues. In: Early detection of occupational diseases, Chapter 9. Geneva, World Health Organization.
471. WHO (1996) Guidelines for drinking-water quality, 2nd ed. Geneva, World Health Organization.
472. Wild D, Eckhardt K, Gocke E, & King MT (1980) Comparative results of short-term in vitro and in vivo mutagenicity tests obtained with selected environmental chemicals. In: Norpoth KH ed. Short-term test systems for detecting carcinogens. New York, Springer-Verlag, p 170 [cited in Beauchamp et al., 1982].
473. Wilmer JL, Kligerman AD, & Erexson GL (1981) Sister chromatid exchange induction and cell cycle inhibition by aniline and its metabolites in human fibroblasts. Environ Mutagen, 3: 627-638.
474. Wilson JT, Enfield CG, Dunlap WJ, Cosby RL, Foster DA, & Baskin LB (1981) Transport and fate of selected organic pollutants in a sandy soil. J Environ Qual, 10: 501-506.
475. Wirth PJ, Dybing E, von Bahr C, & Thorgeirsson SS (1980) Mechanism of N-hydroxy-acetylaryl-amine mutagenicity in the Salmonella test system: Metabolic activation of N-hydroxyphenacetin by liver and kidney fractions from rat, mouse, hamster, and man. Mol Pharmacol, 18: 117-127.
476. Wirtschafter ZT & Wolpaw R (1944) A case of nitrobenzene poisoning. Ann Intern Med, 21: 135-140.
477. Wişniewska-Knypl JM, Jabłońska JK, & Piotrowski JK (1975) Effect of repeated exposure to aniline, nitrobenzene, and benzene on liver microsomal metabolism in the rat. Br J Ind Med, 32: 42-48.
478. Witte F & Zetzsch C (1984) The temperature dependence of the forward-backward reactions of the addition of OH to benzene, aniline and nitrobenzene. In: Physical-chemical behaviour of atmospheric pollutants. Commission of the European Communities, pp 168-176 ((REP) EUR 9436).
479. Witte F, Urbanik E, & Zetzsch C (1986) Temperature dependence of the rate constants for the addition of OH to benzene and to some monosubstituted aromatics (aniline, bromobenzene, and nitrobenzene) and the unimolecular decay of the adducts. Kinetics into a quasi-equilibrium. 2. J Phys Chem, 90: 3251-3259.
480. Wolfe NL (1992) Abiotic transformations of pesticides in natural waters and sediments. In: Schnoor JR ed. Fate of pesticides and chemicals in the environment. Chichester, John Wiley and Sons.
481. Wright-Smith RJ (1929) Poisoning by nitrobenzene or "essence of mirbane" with recovery. Med J Aust, 1: 867-868.
482. Wujcik WJ, Lowe WL, Marks PJ, & Sisk WE (1992) Granular activated carbon pilot treatment studies for explosives removal from contaminated groundwater. Environ Prog, 11: 178-189.
483. Yamamoto T, Yoneyama M, Imanishi M, & Takeuchi M (2000) Flow cytometric detection and analysis of tailless sperm caused by sonication or a chemical agent. J Toxicol Sci, 25: 41-48.
484. Yoshida K, Shigeoka T, & Yamauchi F (1988) Estimation of environmental fate of industrial Chemicals. Toxicol Environ Chem, 17: 69-85.
485. Yoshida T (1962) Experimental studies on the histopathological changes of the optic nerve of rabbits administered with aniline or nitrobenzene. Jpn J Ind Health, 4: 262-280.
486. Yoshioka Y, Ose Y, & Sato T (1985) Testing for the toxicity of chemicals with Tetrahymena pyriformis. Sci Total Environ, 43: 149-157.
487. Yoshioka Y, Nagase H, Ose Y, & Sato T (1986) Evaluation of the test method "activated sludge, respiration inhibition test" proposed by the OECD. Ecotoxicol Environ Saf, 12: 206-212.
488. Yoshioka T, Suzuki T, & Uematsu T (1989) Biotransformation of N-substituted aromatic compounds in mammalian spermatozoa. Nonoxidative formation of N-hydroxy-N-arylacetamides from nitroso aromatic compounds. J Biol Chem, 264: 12432-12438.
489. Young DR, Gossett RW, Baird RB, Brown DA, Taylor PA, & Miille MJ (1983) Wastewater inputs and marine bioaccumulation of priority organic pollutants off southern California. In: Jolley RL, Brungs WA, & Cotruvo JA ed. Water chlorination: Environmental impact and health effects. Vol 4, Book 2: Environmental health and risk; Proceedings of the 4th Conference. Ann Arbor, Michigan, Ann Arbor Science Publishers, pp 871-884.
490. Yu YS & Bailey GW (1992) Soil process and chemical transport. Reduction of nitrobenzene by four sulfide minerals: kinetics, products, and solubility. J Environ Qual, 21: 86-94.
491. Zeise L, Wilson R, & Crouch E (1984) Use of acute toxicity to estimate carcinogenic risk. Risk Anal, 4: 187-199.
492. Zeise L, Crouch E, & Wilson R (1986) A possible relationship between toxicity and carcinogenicity. J Am Coll Toxicol, 5: 137-151.
493. Zeitoun MM (1959) Nitrobenzene poisoning in infants due to inunction with false bitter almond oil. J Trap Pediatr, 5: 73-75.
494. Zeligs M (1929) Aniline and nitrobenzene poisoning in infants. Arch Pediatr, 46: 502-506.
495. Zepp RG & Schlotzhauer PF (1983) Influence of algae on photolysis rates of chemicals in water. Environ Sci Technol, 17: 462-468.
496. Zepp RG, Braun AM, Hoigné J, & Leenheer JA (1987a) Photoproduction of hydrated electrons from natural organic solutes in aquatic environments. Environ Sci Technol, 21: 485-490.
497. Zepp RG, Hoigné J, & Bader M (1987b) Nitrate-induced photooxidation of trace organic chemicals in water. Environ Sci Technol, 21: 443-450.
498. Zoeteman BCJ, Harmsen K, Linders JBHJ, Morra CHF, & Slooff W (1980) Persistent organic pollutants in river water and ground water of the Netherlands. Chemosphere, 9: 231-249.
499. Zuccola P (1919) Nitrobenzene poisoning. J Am Med Assoc, 72: 231(Abstr).