Primary structure and function analysis of the Abrus precatorius agglutinin A chain by site-directed mutagenesis. Pro199 of amphiphilic α- helix h impairs protein synthesis inhibitory activity

Journal of Biological Chemistry

Volumn 275, Issue 3, 2000, Pages 1897-1901

  Liu, Chao Lin ^a   Tsai, Chia Chu ^a   Lin, Su Chang ^b   Wang, Li In ^a   Hsu, Chong Ing ^a   Hwang, Ming Jing ^c   Lin, Jung Yaw ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

^c ACADEMIA SINICA   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

AGGLUTININ; RIBOSOME INACTIVATING PROTEIN; RICIN;

ABRUS; ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BASE PAIRING; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN STRUCTURE; PROTEIN SYNTHESIS INHIBITION; SEQUENCE ANALYSIS; SITE DIRECTED MUTAGENESIS;

ABRIN; AMINO ACID SEQUENCE; ANIMALS; CELL-FREE SYSTEM; CLONING, MOLECULAR; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHORESIS, POLYACRYLAMIDE GEL; ESCHERICHIA COLI; LECTINS; MODELS, GENETIC; MOLECULAR SEQUENCE DATA; MUTAGENESIS, SITE-DIRECTED; PLANT LECTINS; PROTEIN SYNTHESIS INHIBITORS; RABBITS; RECOMBINANT PROTEINS; RETICULOCYTES; RIBOSOMES; SEQUENCE HOMOLOGY, AMINO ACID;

ABRA; ABRUS; ABRUS PRECATORIUS;

EID: 0034695623     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.275.3.1897     Document Type: Article

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