Regulation of phosphatidylserine exposure at the cell surface by the serine-base exchange enzyme system during CD95-induced apoptosis

Biochemical Pharmacology

Volumn 59, Issue 7, 2000, Pages 855-863

  Pelassy, Claudette ^a   Breittmayer, Jean Philippe ^a   Aussel, Claude ^a  

^a INSERM   (France)

Author keywords

Annexin V; Apoptosis; CD95; Jurkat; Phosphatidylserine

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALMODULIN INHIBITOR; CD3 ANTIGEN; CHLORPROMAZINE; FAS ANTIGEN; GRAMICIDIN; LIPOCORTIN 5; N (6 AMINOHEXYL) 5 CHLORO 1 NAPHTHALENESULFONAMIDE; OCTADECYLAMINE; PHOSPHATIDYLSERINE; QUININE; SODIUM AZIDE; THAPSIGARGIN; TRIFLUOPERAZINE; VALINOMYCIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL SURFACE; CYTOCHEMISTRY; ENZYME ACTIVITY; FLUORESCENCE; IN VITRO STUDY; INTRACELLULAR TRANSPORT; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; NONHUMAN; PRIORITY JOURNAL;

ADENOSINE TRIPHOSPHATE; ANTIGENS, CD95; APOPTOSIS; HUMANS; JURKAT CELLS; KINETICS; LYMPHOCYTE ACTIVATION; MEMBRANE POTENTIALS; NITROGENOUS GROUP TRANSFERASES; PHOSPHATIDYLSERINES; SERINE; T-LYMPHOCYTES;

EID: 0033977060     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(99)00383-4     Document Type: Article

References (53)

1. Nagata S. Apoptosis by death factor. Cell. 88:1997;355-365.
2. Kischkel F.C., Hellbardt S., Behrmann I., Germer M., Pawlita M., Krammer P.H., Peter M.E. Cytotoxicity-dependent APO-1 (Fas/CD95)-associated proteins form a death-inducing signaling complex (DISC) with the receptor. EMBO J. 14:1995;5579-5588.
3. Rote N.S., Ng A.K., Dostal-Johnson D.A., Nicholson S.L., Siekman R. Immunologic detection of phosphatidylserine externalization during thrombin-induced platelet activation. Clin Immunol Immunopathol. 66:1993;193-200.
4. Fadok V.A., Voelker D.R., Campbell P.A., Cohen J.J., Bratton D.L., Henson P.M. Exposure of phosphatidylserine on the surface of apoptotic lymphocytes triggers specific recognition and removal by macrophages. J Immunol. 148:1992;2207-2216.
5. Schroit A., Tanaka Y., Madsen J., Fidler I.J. The recognition of red blood cells by macrophages Role of phosphatidylserine and possible implications of phospholipid asymmetry . Biol Cell. 51:1984;227-238.
6. Savill J., Fadok V., Henson P., Haslett C. Phagocyte recognition of cells undergoing apoptosis. Immunol Today. 14:1993;131-136.
7. Martin S.J., Finucane D.M., Amarante-Mendes G.P., O'Brien G.A., Green D.R. Phosphatidylserine externalization during CD95-induced apoptosis of cells and cytoplasts requires ICE/CED-3 protease activity. J Biol Chem. 271:1996;28753-28756.
8. Martin S.J., Reutelingsperger C.P., McGahon A.J., Rader J.A., van Shie R.C., LaFace D.M., Green D.R. Early redistribution of plasma membrane phosphatidylserine is a general feature of apoptosis regardless of the initiating stimulus Inhibition by overexpression of Bcl-2 and Abl . J Exp Med. 182:1995;1545-1556.
9. Aussel C., Pelassy C., Breittmayer J.P. CD95 (Fas/APO-1) induces an increased phosphatidylserine synthesis that precedes its externalization during programmed cell death. FEBS Lett. 431:1998;195-199.
10. 2+-stimulated incorporation of nitrogen bases into microsomal phospholipids. Biochim Biophys Acta. 306:1973;396-402.
11. 2+-dependent biosynthesis of lecithin, phosphatidylethanolamine and phosphatidylserine in rat liver subcellular particles. Biochim Biophys Acta. 296:1973;549-562.
12. Buchanan A.G., Kanfer J.N. Topographical distribution of base exchange activities in rat brain subcellular fractions. J Neurochem. 34:1980;720-725.
13. Kuge O., Nishijima M., Akamatsu Y. A Chinese hamster cDNA encoding a protein essential for phosphatidylserine synthase I activity. J Biol Chem. 266:1991;24184-24189.
14. Kuge O., Saito K., Nishijima M. Cloning of a Chinese hamster ovary (CHO) cDNA encoding phosphatidylserine synthase (PSS) II, overexpression of which suppresses the phosphatidylserine biosynthetic defect of a PSS I-lacking mutant of CHO-K1 cells. J Biol Chem. 272:1997;19133-19139.
15. Baranska J. Mechanism of the ATP-dependent phosphatidylserine synthesis in liver subcellular fractions. FEBS Lett. 256:1989;33-37.
16. Aussel C., Pelassy C., Mary D., Breittmayer J.P., Cousin J.L., Rossi B. Calcium-dependent regulation of phosphatidylserine synthesis in control and activated Jurkat T cells. J Lipid Mediat. 3:1991;267-282.
17. Voelker D.R. Characterization of phosphatidylserine synthesis and translocation in permeabilized animal cells. J Biol Chem. 265:1990;14340-14346.
18. + channel antagonists. Immunopharmacology. 20:1990;97-103.
19. Pelassy C., Aussel C., Fehlmann M. Phospholipid metabolism and T cell activation Receptor triggering is associated with the inhibition of phosphatidylserine synthesis . Cell Signal. 1:1989;99-105.
20. 2+ stores in Jurkat T-cells. Biochem J. 288:1992;785-789.
21. 2+ concentrations. Biochem Mol Biol Int. 31:1993;967-973.
22. Czarny M., Baranska J. Effect of the ionophore A23187, thapsigargin, caffeine and heparin on phosphatidylserine synthesis in rat liver microsomal fraction. Biochem Biophys Res Commun. 194:1993;577-583.
23. Pelassy C., Cattan N., Aussel C. Changes in phospholipid metabolism induced by quinine, 4-aminopyridine and tetraethylammonium in the monocytic cell line THP1. Biochem J. 282:1992;443-446.
24. Aussel C., Breittmayer J.P., Pelassy C., Bernard A. Calmodulin, a junction between two independent immunosuppressive pathways in Jurkat T cells. J Biol Chem. 270:1995;8032-8036.
25. Aussel C., Pelassy C., Bernard A. Oleylamine and stearylamine increase phosphatidylserine synthesis in T cells by synergy with calcium ions. Int J Biochem Cell Biol. 27:1995;597-602.
26. Breittmayer J.P., Pelassy C., Aussel C. Effect of membrane potential on phosphatidylserine synthesis and calcium movements in control and CD3-activated Jurkat T cells. J Lipid Mediat Cell Signal. 13:1996;151-161.
27. Yang Y., Kim D., Fathman G.C. Regulation of programmed cell death following T cell activation in vivo. Int Immunol. 10:1998;175-183.
28. Holmstrom T.H., Chow S.C., Elo I., Coffey E.T., Orrenius S., Sistonen L., Eriksson J.E. Suppression of Fas/APO-1 mediated apoptosis by mitogen-activated kinase signaling. J Immunol. 160:1998;2626-2636.
29. McLeod J.D., Walker L.S., Patel Y.I., Boulougouris G., Sansom D.M. Activation of human T cells with superantigen (staphylococcal enterotoxin B) and CD28 confers resistance to apoptosis via CD95. J Immunol. 160:1998;2072-2079.
30. Hausler P., Papoff G., Eramo A., Reif K., Cantrell D.A., Ruberti G. Protection of CD95-mediated apoptosis by activation of phosphatidylinositide 3-kinase and protein kinase B. Eur J Immunol. 28:1998;57-69.
31. Bligh E.G., Dyer W.J. A rapid method of total lipid extraction and purification. Can J Biochem Physiol. 37:1959;911-917.
32. Niwa Y., Taniguchi S. Phospholipid base exchange in human leukocyte membranes Quantitation and correlation with other phospholipid biosynthetic pathways . Arch Biochem Biophys. 250:1986;345-357.
33. Buchanan A.G., Kanfer J.N. The effects of various incubation temperatures, particulate isolation, and possible role of calmodulin on the activity of the base exchange enzymes of rat brain. J Neurochem. 35:1980;814-822.
34. + channel blockers specifically enhance the activity of the serine base exchange system in Jurkat T cells. Pharmacology. 47:1993;28-35.
35. Kanfer J.N., McCartney D.G. Modulation of the serine base exchange enzyme activity of rat brain membranes by amphiphilic cations and amphiphilic anions. J Neurochem. 60:1993;1228-1235.
36. Singh I.N., Massarelli R., Kanfer J.N. Modulation of phosphatidylserine homeostasis by amphiphilic cations in a human neuronal cell line, LA-N-2. J Lipid Mediat. 5:1992;301-311.
37. Singh I.N., Sorrentino G., Massarelli R., Kanfer J.N. Oleylamine and sphingosine stimulation of phosphatidylserine synthesis by LA-N-2 cells is protein kinase C independent. FEBS Lett. 296:1992;166-168.
38. Czarny M., Sabala P., Baranska J. ATP-dependent phosphatidylserine formation in animal cells as a base exchange reaction. Acta Biochim Pol. 40:1993;301-308.
39. Balasubramanian K., Chandra J., Schroit A.J. Immune clearance of phosphatidylserine-expressing cells by phagocytes. The role of β2-glycoprotein I in macrophage recognition. J Biol Chem. 272:1997;31113-31117.
40. Sambrano G.R., Steinberg D. Recognition of oxidatively damaged and apoptotic cells by an oxidized low density lipoprotein receptor on mouse peritoneal macrophages Role of membrane phosphatidylserine . Proc Natl Acad Sci USA. 92:1995;1396-1400.
41. Ashman R.F., Peckham D., Alhasan S., Stunz L.L. Membrane unpacking and the rapid disposal of apoptotic cells. Immunol Lett. 48:1995;159-166.
42. Tait J.F., Gibson D. Phospholipid binding of annexin V Effects of calcium and membrane phosphatidylserine content . Arch Biochem Biophys. 298:1992;187-191.
43. Vermes I., Haanen C., Steffens-Nakken H., Reutelingsperger C. A novel assay for apoptosis. Flow cytometric detection of phosphatidylserine expression on early apoptotic cells using fluorescein labelled Annexin V. J Immunol Methods. 184:1995;39-51.
44. Koopman G., Reutelingsperger C.P., Kuijten G.A., Keehnen R.M., Pals S.T., van Oers M.H. Annexin V for flow cytometric detection of phosphatidylserine expression on B cells undergoing apoptosis. Blood. 84:1994;1415-1420.
45. Bratton D.L., Fadok V.A., Richter D.A., Kailey J.M., Guthrie L.A., Henson P.M. Appearance of phosphatidylserine on apoptotic cells requires calcium-mediated nonspecific flip-flop and is enhanced by loss of the aminophospholipid translocase. J Biol Chem. 272:1997;26159-26165.
46. Zhao J., Zhou Q., Wiedmer T., Sims P.J. Level of expression of phospholipid scramblase regulates induced movement of phosphatidylserine to the cell surface. J Biol Chem. 273:1998;6603-6606.
47. Naito M., Nagashima K., Mashima T., Tsuruo T. Phosphatidylserine externalization is a downsteam event of interleukin 1B-converting enzyme family protease activation during apoptosis. Blood. 89:1997;2060-2066.
48. Vanags D.M., Porn-Ares M.I., Coppola S., Burgess D.H., Orrenius S. Protease involvement in fodrin cleavage and phosphatidylserine exposure in apoptosis. J Biol Chem. 271:1996;31075-31085.
49. Hirata H., Takahashi A., Kobayashi S., Yonehara S., Sawai H., Okazaki T., Yamamoto K., Sasada M. Caspases are activated in a branched protease cascade and control distinct downstream processes in Fas-induced apoptosis. J Exp Med. 187:1998;587-600.
50. Chacon-Cruz E., Oelberg D.G., Davis P., Buescher E.S. Membrane depolarization and depletion of intracellular calcium stores are associated with delay of apoptosis in human neutrophils. J Leukoc Biol. 64:1998;759-766.
51. Zhuang J., Ren Y., Snowden R.T., Zhu H., Gogvadze V., Savill J.S., Cohen G.M. Dissociation of phagocyte recognition of cells undergoing apoptosis from other features of the apoptotic program. J Biol Chem. 273:1998;15628-15632.
52. Li W., Tait J.F. Regulatory effect of CD9 on calcium-stimulated phosphatidylserine exposure in Jurkat T lymphocytes. Arch Biochem Biophys. 351:1998;89-95.
53. Dumaurier M.J., Pelassy C., Breittmayer J.P., Aussel C. Regulation of the serine base exchange enzyme system by CD4 Effects of monoclonal antibodies, jacalin, interleukin 16 and the HIV membrane protein gp120 . Biochem J. 329:1998;49-54.