Asymmetric synthesis of α,α-difluoro-β-amino acid derivatives from enantiomerically pure N-tert-butylsulfinimines

Journal of Organic Chemistry

Volumn 67, Issue 23, 2002, Pages 8276-8279

  Staas, Donnette D ^a   Savage, Kelly L ^a   Homnick, Carl F ^a   Tsou, Nancy N ^a   Ball, Richard G ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DIASTEREOMERIC RATIOS;

ADDITION REACTIONS; AMINES; AMINO ACIDS; ESTERS; SUBSTITUTION REACTIONS;

SYNTHESIS (CHEMICAL);

ALPHA,ALPHA DIFLUORO BETA AMINO ACID DERIVATIVE; AMINO ACID DERIVATIVE; BETA AMINO ACID; DOCETAXEL; NATURAL PRODUCT; ORGANOMETALLIC COMPOUND; OXAZOLIDINONE DERIVATIVE; REAGENT; SULFUR DERIVATIVE; UNCLASSIFIED DRUG; AMINO ACID; FLUORINE; IMINE; SULFONAMIDE; TERT BUTYLSULFONAMIDE; TERT-BUTYLSULFONAMIDE;

ARTICLE; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMICAL REACTION; CHEMICAL STRUCTURE; CHIRALITY; DIASTEREOISOMER; ENANTIOMER; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PROTON NUCLEAR MAGNETIC RESONANCE; STEREOCHEMISTRY; SYNTHESIS; THERMODYNAMICS; CHEMISTRY; STEREOISOMERISM;

AMINO ACIDS; FLUORINE; IMINES; STEREOISOMERISM; SULFONAMIDES;

EID: 0037111684     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo0259313     Document Type: Article

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