Cardiovascular effects of the adenosine A1 receptor agonist N6-cyclopentyladenosine (CPA) decisive for its therapeutic efficacy in sarin poisoning

Archives of Toxicology

Volumn 78, Issue 1, 2004, Pages 34-39

  Joosen, Marloes J A ^a   Bueters, Tjerk J H ^a   Van Helden, Herman P M ^a  

^a TNO   (Netherlands)

Author keywords

8 p Sulphophenyltheophylline (8 PST); Adenosine A1 receptor; Cardiovascular effects; N6 Cyclopentyladenosine (CPA); Organophosphate; Sarin

Indexed keywords

6 N CYCLOPENTYLADENOSINE; 8 (4 SULFOPHENYL)THEOPHYLLINE; ADENOSINE A1 RECEPTOR AGONIST; SARIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRADYCARDIA; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE ASSOCIATION; DRUG EFFICACY; HYPOTENSION; INTOXICATION; LOW DRUG DOSE; MALE; MORTALITY; NONHUMAN; PRIORITY JOURNAL; RAT; SARIN INTOXICATION;

ADENOSINE; ANIMALS; BRADYCARDIA; CHEMICAL WARFARE AGENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG ANTAGONISM; DRUG THERAPY, COMBINATION; HEART DISEASES; HYPOTENSION; INJECTIONS, INTRAMUSCULAR; MALE; POISONING; RATS; RECEPTORS, PURINERGIC P1; SARIN; THEOPHYLLINE;

ANIMALIA;

EID: 1442278711     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-003-0513-4     Document Type: Article

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