Mevastatin, an inhibitor of HMG-CoA reductase, induces apoptosis, differentiation and Rap1 expression in HL-60 cells

Physiological Chemistry and Physics and Medical NMR

Volumn 34, Issue 1, 2002, Pages 1-15

  Kanno, Tomoko ^a   Kobuchi, Hirotsugu ^b   Kajitani, Noriko ^a   Utsumi, Toshihiko ^c   Yano, Hiromi ^d   Horton, Alan A ^a   Yasuda, Tatsuji ^b   Utsumi, Kozo ^a  

^a University of Tokyo   (Japan)

^b OKAYAMA UNIVERSITY MEDICAL SCHOOL   (Japan)

^c YAMAGUCHI UNIVERSITY   (Japan)

^d KAWASAKI UNIVERSITY OF MEDICAL WELFARE   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

CASP3 PROTEIN, HUMAN; CASPASE; CASPASE 3; COMPACTIN; CYTOCHROME C; DRUG DERIVATIVE; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 1BETA CONVERTING ENZYME; MEVINOLIN; RAP1 PROTEIN;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL DIFFERENTIATION; CELL MEMBRANE POTENTIAL; CELL STRAIN HL 60; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; ENZYME ACTIVATION; HUMAN; METABOLISM; MITOCHONDRION; PHYSIOLOGY; REPRODUCIBILITY; SENSITIVITY AND SPECIFICITY;

APOPTOSIS; CASPASE 1; CASPASE 3; CASPASES; CELL DIFFERENTIATION; CYTOCHROME C GROUP; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME ACTIVATION; HL-60 CELLS; HUMANS; HYDROXYMETHYLGLUTARYL-COA REDUCTASE INHIBITORS; LOVASTATIN; MEMBRANE POTENTIALS; MITOCHONDRIA; RAP1 GTP-BINDING PROTEINS; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY;

EID: 0043076460     PISSN: 07486642     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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