New 4-[ω-(diarylmethylamino)alkyl]- and 4-[ω-(diarylmethoxy)alkyl]-1-arylpiperazines as selective 5-HT1A/5-HT2A receptor ligands with differentiated in vivo activity

Polish Journal of Pharmacology

Volumn 56, Issue 6, 2004, Pages 743-754

  Paluchowska, Maria H ^a   Charakchieva Minol, Sijka ^a   Tatarczyńska, Ewa ^a   Kłodzińska, Aleksandra ^a   Stachowicz, Katarzyna ^a   Chojnacka Wójcik, Ewa ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

Author keywords

Arylpiperazine derivatives; Selective 5 HT1A 5 HT2A ligands; Structure activity relationship

Indexed keywords

1 (2 METHOXYPHENYL)PIPERAZINE; 1 (3 CHLOROPHENYL) 4 [2 [BIS(4 METHYLPHENYL)METHOXY]ETHYL]PIPERAZINE; 1 (3 CHLOROPHENYL) 4 [2 [BIS(4 METHYLPHENYL)METHYLAMINO]ETHYL]PIPERAZINE; 1 (3 CHLOROPHENYL) 4 [3 [BIS (4 METHYLPHENYL)METHOXY]ETHYL]PIPERAZINE; 1 (3 CHLOROPHENYL) 4 [3 [BIS(4 METHYLPHENYL)METHYLAMINO]PROPYL]PIPERAZINE; 2 DIPROPYLAMINO 8 HYDROXYTETRALIN; 4 [2 [BIS(4 CHLOROPHENYL)METHOXY]ETHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [2 [BIS(4 CHLOROPHENYL)METHYLAMINO]ETHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [2 [BIS(4 FLUOROPHENYL)METHOXY]ETHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [2 [BIS(4 FLUOROPHENYL)METHOXYLAMINO]PROPYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [2 [BIS(4 FLUOROPHENYL)METHYLAMINO]ETHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [2 [BIS(4 METHYLPHENYL)METHYLAMINO]ETHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [3 [BIS(4 CHLOROPHENYL)METHYLAMINO]PROPYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [3 [BIS(4 FLUOROPHENYL)METHOXY]PROPYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [3 [BIS(4 FLUOROPHENYL)METHYLAMINO]PROPYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [3 [BIS(4 METHYLPHENYL)METHOXY]PROPHYL] 1 (2 METHOXYPHENYL)PIPERAZINE; 4 [3 [BIS(4 METHYPHENYL)METHYLAMINO]PROPYL] 1 (2 METHOXYPHENYL)PIPERAZINE; ALPHA 1 ADRENERGIC RECEPTOR; N [2 [4 (2 METHOXYPHENYL) 1 PIPERAZINYL]ETHYL] N (2 PYRIDYL)CYCLOHEXANECARBOXAMIDE; PIPERAZINE DERIVATIVE; RESERPINE; SEROTONIN 1A AGONIST; SEROTONIN 1A ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BODY TEMPERATURE; CONTROLLED STUDY; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; IN VITRO STUDY; IN VIVO STUDY; LIP; MALE; MOUSE; NONHUMAN; POSTSYNAPTIC MEMBRANE; PRESYNAPTIC MEMBRANE; RAT; RECEPTOR AFFINITY; STRUCTURE ACTIVITY RELATION;

ANIMALS; BEHAVIOR, ANIMAL; BODY TEMPERATURE; DOSE-RESPONSE RELATIONSHIP, DRUG; MALE; MICE; MOLECULAR STRUCTURE; PIPERAZINES; RATS; RATS, WISTAR; RECEPTOR, SEROTONIN, 5-HT1A; RECEPTOR, SEROTONIN, 5-HT2A; SEROTONIN 5-HT1 RECEPTOR ANTAGONISTS; SEROTONIN 5-HT2 RECEPTOR ANTAGONISTS; SEROTONIN ANTAGONISTS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 14244260755     PISSN: 12306002     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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