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Volumn 9, Issue 4, 2004, Pages 347-354

The past and the future of cancer genetics

Author keywords

Cancer epigenetics; Cancer genetics; Gene mutation; Genomic instability; Protooncogenes; Tumor suppressor genes

Indexed keywords

ABELSON KINASE; ADENOVIRUS VECTOR; ANTINEOPLASTIC AGENT; APC PROTEIN; ARF PROTEIN; ATM PROTEIN; BRCA1 PROTEIN; BRCA2 PROTEIN; CHECKPOINT KINASE 2; EPIDERMAL GROWTH FACTOR RECEPTOR 2; FIBROBLAST GROWTH FACTOR; GENOMIC DNA; K RAS PROTEIN; MYC PROTEIN; ONYX 015; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; PLATELET DERIVED GROWTH FACTOR; PROTEIN E6; PROTEIN E7; PROTEIN FARNESYLTRANSFERASE; PROTEIN FARNESYLTRANSFERASE INHIBITOR; PROTEIN MDM2; PROTEIN MLH1; PROTEIN MSH2; PROTEIN P16; PROTEIN P53; RETINOBLASTOMA PROTEIN; TRASTUZUMAB; UNINDEXED DRUG; VASCULOTROPIN; VON HIPPEL LINDAU PROTEIN;

EID: 14044276930     PISSN: 11070625     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (3)

References (52)
  • 2
    • 0001769577 scopus 로고
    • Uber mehpolige mitosen als mittel zur analyse des zellkerns
    • Bovery T. Uber mehpolige mitosen als mittel zur analyse des zellkerns. Verh D Phys Med Ges Wurzberg NF 1902; 35: 67-90.
    • (1902) Verh. D. Phys. Med. Ges. Wurzberg NF , vol.35 , pp. 67-90
    • Bovery, T.1
  • 3
    • 0008118298 scopus 로고
    • Uber die konstitution der chromatischen kernsubstanz
    • Bovery T. Uber die konstitution der chromatischen kernsubstanz. Verh D Zool Ges 1903; 13.
    • (1903) Verh. D. Zool. Ges. , pp. 13
    • Bovery, T.1
  • 4
    • 0003797440 scopus 로고
    • Ergebnisse uber die konstitution der chromatischen substanz des zellkens
    • (Gustav Fisher, Jena)
    • Bovery T. Ergebnisse uber die konstitution der chromatischen substanz des zellkens. (Gustav Fisher, Jena) 1904.
    • (1904)
    • Bovery, T.1
  • 5
    • 0035150912 scopus 로고    scopus 로고
    • The molecular biology of cancer
    • Bertram JS. The molecular biology of cancer. Mol Asp Med 2001; 21: 167-223.
    • (2001) Mol. Asp. Med. , vol.21 , pp. 167-223
    • Bertram, J.S.1
  • 6
    • 72849159485 scopus 로고
    • Chromosomes of normal and leukemic human leucocytes
    • Nowell P, Hungerford D. Chromosomes of normal and leukemic human leucocytes. J Natl Cancer Inst 1960; 25:80.
    • (1960) J. Natl. Cancer Inst. , vol.25 , pp. 80
    • Nowell, P.1    Hungerford, D.2
  • 7
    • 0019380255 scopus 로고
    • Enemies within: The genesis of retroviral oncogenes
    • Bishop JM. Enemies within: the genesis of retroviral oncogenes. Cell 1981; 23: 5-6.
    • (1981) Cell , vol.23 , pp. 5-6
    • Bishop, J.M.1
  • 8
    • 0015847039 scopus 로고
    • A new technique for the assay of infectivity of human adenovirus 5 DNA
    • Graham FL, van der Eb AJ. A new technique for the assay of infectivity of human adenovirus 5 DNA. Virology 1973; 52: 456-467.
    • (1973) Virology , vol.52 , pp. 456-467
    • Graham, F.L.1    van der Eb, A.J.2
  • 9
    • 0016345051 scopus 로고
    • Size and location of the transforming region in human adenovirus type 5 DNA
    • Graham FL, van der Eb AJ, Heijnher HI. Size and location of the transforming region in human adenovirus type 5 DNA. Nature 1974; 251: 687-691.
    • (1974) Nature , vol.251 , pp. 687-691
    • Graham, F.L.1    van der Eb, A.J.2    Heijnher, H.I.3
  • 10
    • 0020132123 scopus 로고
    • Isolation of a transforming sequence from a human bladder carcinoma cell line
    • Shih C, Weinberg RA. Isolation of a transforming sequence from a human bladder carcinoma cell line. Cell 1982; 29: 161-169.
    • (1982) Cell , vol.29 , pp. 161-169
    • Shih, C.1    Weinberg, R.A.2
  • 11
    • 0020046441 scopus 로고
    • Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells
    • Goldfarb M, Shimizu K, Perucho M, Wigler M. Isolation and preliminary characterization of a human transforming gene from T24 bladder carcinoma cells. Nature 1982; 296: 404-409.
    • (1982) Nature , vol.296 , pp. 404-409
    • Goldfarb, M.1    Shimizu, K.2    Perucho, M.3    Wigler, M.4
  • 12
    • 0027970838 scopus 로고
    • Chromosomal translocations in human cancer
    • Rabbits TH. Chromosomal translocations in human cancer. Nature 1994; 372: 143-149.
    • (1994) Nature , vol.372 , pp. 143-149
    • Rabbits, T.H.1
  • 14
    • 0034015947 scopus 로고    scopus 로고
    • K-ras mutation: Early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers-a review
    • Minamoto T. Mai M, Ronai Z et al. K-ras mutation: early detection in molecular diagnosis and risk assessment of colorectal, pancreas, and lung cancers-a review. Cancer Detect Prev 2000; 24: 1-12.
    • (2000) Cancer Detect. Prev. , vol.24 , pp. 1-12
    • Minamoto, T.1    Mai, M.2    Ronai, Z.3
  • 15
    • 0032704708 scopus 로고    scopus 로고
    • Ras protein farnesyl-transferase: A strategic target for anticancer therapeutic development
    • Rowinsky EK, Windle JJ, Hoff D et al. Ras protein farnesyl-transferase: a strategic target for anticancer therapeutic development. J Clin Oncol 1999; 17: 3631-3652.
    • (1999) J. Clin. Oncol. , vol.17 , pp. 3631-3652
    • Rowinsky, E.K.1    Windle, J.J.2    Hoff, D.3
  • 16
    • 0034691674 scopus 로고    scopus 로고
    • Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulate angiogenesis
    • Yen L, You XL, AlMoustafa AE et al. Heregulin selectively upregulates vascular endothelial growth factor secretion in cancer cells and stimulate angiogenesis. Oncogene 2000; 19: 3460-3469.
    • (2000) Oncogene , vol.19 , pp. 3460-3469
    • Yen, L.1    You, X.L.2    AlMoustafa, A.E.3
  • 18
    • 0036781812 scopus 로고    scopus 로고
    • c-myc: More than just a matter of life and death
    • Pelengaris S, Khan M, Evan G. c-myc: more than just a matter of life and death. Nat Rev Cancer 2002; 2: 764-776.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 764-776
    • Pelengaris, S.1    Khan, M.2    Evan, G.3
  • 19
    • 0032715993 scopus 로고    scopus 로고
    • Activation and targeting of immunoglobulin switch recombination by activities induced by EBV infection
    • Li MJ, Maizels N. Activation and targeting of immunoglobulin switch recombination by activities induced by EBV infection. J Immunol 1999; 163: 6659-6664.
    • (1999) J. Immunol. , vol.163 , pp. 6659-6664
    • Li, M.J.1    Maizels, N.2
  • 21
    • 0017225738 scopus 로고
    • Suppression of malignancy in human cells
    • Stanbridge EJ. Suppression of malignancy in human cells. Nature 1976; 260: 17-20.
    • (1976) Nature , vol.260 , pp. 17-20
    • Stanbridge, E.J.1
  • 22
    • 0015043748 scopus 로고
    • Mutation and cancer: Statistical study of retinoblastoma
    • Knudson AG. Mutation and cancer: statistical study of retinoblastoma. Proc Natl Acad Sci USA 1971; 68: 820-823.
    • (1971) Proc. Natl. Acad. Sci. USA , vol.68 , pp. 820-823
    • Knudson, A.G.1
  • 23
    • 0001201784 scopus 로고
    • Mutation and human cancer
    • Knudson AG. Mutation and human cancer. Adv Cancer Res 1973; 17: 317-352.
    • (1973) Adv. Cancer Res. , vol.17 , pp. 317-352
    • Knudson, A.G.1
  • 24
    • 0035522894 scopus 로고    scopus 로고
    • Two genetic hits (more or less) to cancer
    • Knudson AG. Two genetic hits (more or less) to cancer. Nat Rev Cancer 2001; 1: 157-162.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 157-162
    • Knudson, A.G.1
  • 25
    • 0017157366 scopus 로고
    • Partial deletions and trisomies of chromosome 13: Mapping of bands associated with particular malformations
    • Noel B, Quack B, Rethore MO. Partial deletions and trisomies of chromosome 13: mapping of bands associated with particular malformations. Clin Genet 1976; 9: 593-602.
    • (1976) Clin. Genet. , vol.9 , pp. 593-602
    • Noel, B.1    Quack, B.2    Rethore, M.O.3
  • 26
    • 0344671608 scopus 로고    scopus 로고
    • Functions of the retinoblastoma protein
    • Kaelin WG Jr. Functions of the retinoblastoma protein. Bioessays 1999; 21: 950-958.
    • (1999) Bioessays , vol.21 , pp. 950-958
    • Kaelin Jr., W.G.1
  • 27
    • 0035063183 scopus 로고    scopus 로고
    • The Rb/E2F pathway and cancer
    • Nevins JR. The Rb/E2F pathway and cancer. Hum Mol Genet 2001; 10: 699-703.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 699-703
    • Nevins, J.R.1
  • 29
    • 0036511615 scopus 로고    scopus 로고
    • The role of human papilloma viruses in human cancers
    • Munger K. The role of human papilloma viruses in human cancers. Front Biosci 2002; 7: d641-d649.
    • (2002) Front. Biosci. , vol.7
    • Munger, K.1
  • 30
    • 0036559896 scopus 로고    scopus 로고
    • Papillomaviruses and cancer: From basic studies to clinical application
    • zur Hausen H. Papillomaviruses and cancer: from basic studies to clinical application. Nat Rev Cancer 2002; 2: 342-350.
    • (2002) Nat. Rev. Cancer , vol.2 , pp. 342-350
    • zur Hausen, H.1
  • 31
    • 0030445324 scopus 로고    scopus 로고
    • Expression of the retinoblastoma (Rb) tumor suppressor gene inhibits tumor cell invasion in vitro
    • Li J, Hu SX, Perng GS et al. Expression of the retinoblastoma (Rb) tumor suppressor gene inhibits tumor cell invasion in vitro. Oncogene 1996; 13: 2379-2386.
    • (1996) Oncogene , vol.13 , pp. 2379-2386
    • Li, J.1    Hu, S.X.2    Perng, G.S.3
  • 32
    • 0011272360 scopus 로고    scopus 로고
    • The p53 database
    • December (Accessed October 22, 2002 at)
    • Soussi T, Gallou C, Beroud C. The p53 database. December 2001. (Accessed October 22, 2002, at http://p53.curie.fr.).
    • (2001)
    • Soussi, T.1    Gallou, C.2    Beroud, C.3
  • 33
    • 0029922621 scopus 로고    scopus 로고
    • p53 tumor suppressor gene: From the basic research laboratory to the clinic-an abridged historical perspective
    • Harris CC. p53 tumor suppressor gene: from the basic research laboratory to the clinic-an abridged historical perspective. Carcinogenesis 1996; 17: 1187-1198.
    • (1996) Carcinogenesis , vol.17 , pp. 1187-1198
    • Harris, C.C.1
  • 34
    • 0032892932 scopus 로고    scopus 로고
    • Activation of p53 by oncogenes
    • Lowe SW. Activation of p53 by oncogenes. Endocr Relat Cancer 1999; 6: 45-48.
    • (1999) Endocr. Relat. Cancer , vol.6 , pp. 45-48
    • Lowe, S.W.1
  • 35
    • 0035751937 scopus 로고    scopus 로고
    • Assessing TP53 status in human tumors to evaluate clinical outcome
    • Soussi T, Beroud C. Assessing TP53 status in human tumors to evaluate clinical outcome. Nat Rev Cancer 2001; 1: 233-240.
    • (2001) Nat. Rev. Cancer , vol.1 , pp. 233-240
    • Soussi, T.1    Beroud, C.2
  • 36
    • 0037221767 scopus 로고    scopus 로고
    • TP53 and breast cancer
    • Borresen-Dale AL. TP53 and breast cancer. Hum Mut 2003; 21: 292-300.
    • (2003) Hum. Mut. , vol.21 , pp. 292-300
    • Borresen-Dale, A.L.1
  • 37
    • 0036710675 scopus 로고    scopus 로고
    • Regulation of p53: Intricate loops and delicate balances
    • Oren M, Damalas A, Gottlieb T et al. Regulation of p53: intricate loops and delicate balances. Biochem Pharmacol 2002; 64: 865-871.
    • (2002) Biochem. Pharmacol. , vol.64 , pp. 865-871
    • Oren, M.1    Damalas, A.2    Gottlieb, T.3
  • 38
    • 0033887419 scopus 로고    scopus 로고
    • The current status of gene therapy
    • Clayman GL. The current status of gene therapy. Semin Oncol 2000; 27:39-43.
    • (2000) Semin. Oncol. , vol.27 , pp. 39-43
    • Clayman, G.L.1
  • 39
    • 0033831080 scopus 로고    scopus 로고
    • A controlled trial of intratumoral ONYX-15, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer
    • Khuri FR, Nemunaitis J, Ganly I et al. A controlled trial of intratumoral ONYX-15, a selectively-replicating adenovirus, in combination with cisplatin and 5-fluorouracil in patients with recurrent head and neck cancer. Nat Med 2000; 6: 879-885.
    • (2000) Nat. Med. , vol.6 , pp. 879-885
    • Khuri, F.R.1    Nemunaitis, J.2    Ganly, I.3
  • 40
    • 10744221485 scopus 로고    scopus 로고
    • In vivo activation of the p53 pathway by small-molecule antagonists of mdm2
    • Vasillev LT, Vu BT, Graves B et al. In vivo activation of the p53 pathway by small-molecule antagonists of mdm2. Science 2004; 303: 844-848.
    • (2004) Science , vol.303 , pp. 844-848
    • Vasillev, L.T.1    Vu, B.T.2    Graves, B.3
  • 41
    • 0025633582 scopus 로고
    • Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms
    • Malkin D, Li FP, Strong LC et al. Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms. Science 1990; 250: 1233-1238.
    • (1990) Science , vol.250 , pp. 1233-1238
    • Malkin, D.1    Li, F.P.2    Strong, L.C.3
  • 42
    • 0032730774 scopus 로고    scopus 로고
    • Genetic susceptibility to non-polyposis colorectal cancer
    • Lynch HT, de la Chapelle A. Genetic susceptibility to non-polyposis colorectal cancer. J Med Genet 1999; 36: 801-818.
    • (1999) J. Med. Genet. , vol.36 , pp. 801-818
    • Lynch, H.T.1    de la Chapelle, A.2
  • 44
  • 45
    • 0028113345 scopus 로고
    • A strong candidate for the breast and ovarian cancer susceptibility gene: BRCA1
    • Miky Y, Swensen J, Shattuck-Eldens D et al. A strong candidate for the breast and ovarian cancer susceptibility gene: BRCA1. Science 1994; 266: 66-71.
    • (1994) Science , vol.266 , pp. 66-71
    • Miky, Y.1    Swensen, J.2    Shattuck-Eldens, D.3
  • 46
    • 0028330276 scopus 로고
    • Risk of cancer in BRCA1-mutation carriers
    • Ford D, Easton DF, Bishop DT et al. Risk of cancer in BRCA1-mutation carriers. Lancet 1994; 343: 692-695.
    • (1994) Lancet , vol.343 , pp. 692-695
    • Ford, D.1    Easton, D.F.2    Bishop, D.T.3
  • 47
    • 0006713602 scopus 로고
    • Identification of the breast cancer susceptibility gene BRCA2
    • Wooster R, Bignell G, Lancaster J et al. Identification of the breast cancer susceptibility gene BRCA2. Nature 1995; 378: 789-792.
    • (1995) Nature , vol.378 , pp. 789-792
    • Wooster, R.1    Bignell, G.2    Lancaster, J.3
  • 50
    • 0037370476 scopus 로고    scopus 로고
    • The genetics and genomics of cancer
    • Balmain A, Gray J, Ponder B. The genetics and genomics of cancer. Nat Genet 2003; 33: 238244.
    • (2003) Nat. Genet. , vol.33 , pp. 238244
    • Balmain, A.1    Gray, J.2    Ponder, B.3
  • 51
    • 0020699979 scopus 로고
    • Hypomethylation distinguishes genes of some human cancers from their normal counterparts
    • Feinberg AP, Vogelstein B. Hypomethylation distinguishes genes of some human cancers from their normal counterparts. Nature 1983; 301: 89-92.
    • (1983) Nature , vol.301 , pp. 89-92
    • Feinberg, A.P.1    Vogelstein, B.2
  • 52
    • 1042278765 scopus 로고    scopus 로고
    • The history of cancer epigenetics
    • Feinberg AP, Tycko B. The history of cancer epigenetics. Nat Rev Cancer 2004; 4: 143-153.
    • (2004) Nat. Rev. Cancer , vol.4 , pp. 143-153
    • Feinberg, A.P.1    Tycko, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.