Activation and targeting of immunoglobulin switch recombination by activities induced by EBV infection

Journal of Immunology

Volumn 163, Issue 12, 1999, Pages 6659-6664

  Li, Ming Jie ^a,b   Maizels, Nancy ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b CITY OF HOPE NATIONAL MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DNA BINDING; EPSTEIN BARR VIRUS; GENE ACTIVATION; GENE FREQUENCY; GENE TARGETING; GENE TRANSLOCATION; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNOGLOBULIN GENE; NONHUMAN; ONCOGENE C MYC; PRIORITY JOURNAL; TRANSCRIPTION REGULATION; VIRUS INFECTION;

ADJUVANTS, IMMUNOLOGIC; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; GENE REARRANGEMENT, B-LYMPHOCYTE, HEAVY CHAIN; GENE TARGETING; GENOME, VIRAL; HERPESVIRUS 4, HUMAN; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULIN HEAVY CHAINS; LYMPHOMA, B-CELL; RECOMBINATION, GENETIC; TRANS-ACTIVATORS; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR CELLS, CULTURED;

EID: 0032715993     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (29)

1. Miller, G. 1990. Epstein-Barr virus: biology, pathogenesis, and medical aspects. In Virology, B. N. Fields and D. M. Knipe, eds. Raven Press, New York, p. 1921.
2. Purtilo, D. T., R. S. Strobach, M. Okano, and J. R. Davis. 1992. Epstein-Barr virus-associated lymphoproliferative disorders. Lab. Invest. 67:5.
3. Kolman, J. L., C. J. Kolman, and G. Miller. 1992. Marked variation in the size of genomic plasmids among members of a family of related Epstein-Barr viruses. Proc. Natl. Acad. Sci. USA 89:7772.
4. Rooney, C., N. Taylor, J. Countryman, H. Jenson, J. Kolman, and G. Miller. 1988. Genome rearrangements activate the Epstein-Barr virus gene whose product disrupts latency. Proc. Natl. Acad. Sci. USA 85:9801.
5. Leung, H., and N. Maizels. 1992. Transcriptional regulatory elements stimulate recombination in extrachromosomal substrates carrying immunoglobulin switch-region sequences. Proc. Natl. Acad. Sci. USA 89:4154.
6. Leung, H., and N. Maizels. 1994. Regulation and targeting of recombination in extrachromosomal substrates carrying immunoglobulin switch region sequences. Mol. Cell. Biol. 14:1450.
7. Hengstschläger, M., N. Maizels, and H. Leung. 1995. Targeting and regulation of immunoglobulin gene somatic hypermutation and isotype switch recombination. Prog. Nucleic Acids Res. Mol. Biol. 50:67.
8. Li, M. J., H. Leung, and N. Maizels. 1996. Extrachromosomal substrates to study immunoglobulin heavy chain class switch recombination in mammalian B cells. In Methods in Molecular Genetics, Vol. 8. K. Adolph, W., ed. Academic Press, Orlando, p. 375.
9. Li, M. J., W. Chung, and N. Maizels. 1997. Developmental specificity of immunoglobulin heavy chain switch region recombination activities. Mol. Immunol. 34:201.
10. Daniels, G. A., and M. R. Lieber. 1995. Strand specificity in the transcriptional targeting of recombination at immunoglobulin switch sequences. Proc. Natl. Acad. Sci. USA 92:5625.
11. Li, J., G. A. Daniels, and M. R. Lieber. 1996. Asymmetric mutation around the recombination break point of immunoglobulin class switch sequences on extra-chromosomal substrates. Nucleic Acids Res. 24:2104.
12. Kinoshita, K., J. Tashiro, S. Tomita, C.G. Lee, and T. Honjo. 1998. Target specificity of immunoglobulin class switch recombination is not determined by nucleotide sequences of S regions. Immunity 9:849.
13. Stavnezer, J., S. P. Bradley, N. Rousseau, T. Pearson, A. Shanmubam, D. J. Waite, P. R. Rogers, and A. L. Kenter. 1999. Switch recombination in a transfected plasmid occurs preferentially in a B cell line that undergoes switch recombination of its chromosomal Ig heavy chain genes. J. Immunol. 163:2028.
14. H gene switch recombination. J. Immunol. 161:1336.
15. Ott, D. E., F. W. Alt, and K. B. Marcu. 1987. Immunoglobulin heavy chain switch region recombination within a retroviral vector in murine pre-B cells. EMBO J. 6:577.
16. Williams, M., and N. Maizels. 1991. LR1, a lipopolysaccharide-responsive factor with binding sites in the immunoglobulin switch regions and heavy-chain enhancer. Genes Dev. 5:2353.
17. Hanakahi, L. A., L. A. Dempsey, M. J. Li, and N. Maizels. 1997. Nucleolin is one component of the B cell-specific transcription factor and switch region binding protein, LR1. Proc. Natl. Acad. Sci. USA 94:3605.
18. Dempsey, L. A., M. J. Li, A. DePace, P. Bray-Ward, and N. Maizels. 1998. The human HNRPD locus maps to 4q21 and encodes a highly conserved protein. Genomics 49:378.
19. Brys, A., and N. Maizels. 1994. LR1 regulates c-myc transcription in B-cell lymphomas. Proc. Natl. Acad. Sci. USA 91:4915.
20. Bulfone-Paus, S., L. A. Dempsey, and N. Maizels. 1995. Host factors LR1 and Sp1 regulate the Fp promoter of Epstein-Barr virus. Proc. Natl. Acad. Sci. USA 92:8293.
21. Pulvertaft, R. J. V. 1965. A study of malignant tumors in Nigeria by short-term tissue culture. J. Clin. Pathol. 18:261.
22. Takada, K., and Y. Ono. 1989. Synchronous and sequential activation of latently infected Epstein-Barr virus genomes. J Virol. 63:445.
23. Menezes, J., W. Leibold, G. Klein, and G. Clements. 1975. Establishment and characterization of an Epstein-Barr virus (EBV)-negative lymphoblastoid B cell line (BJA-B) from an exceptional, EBV-genome-negative African Burkitt's lymphoma. Biomedicine 22:276.
24. Lacy, J., W. P. Summers, M. Watson, P. M. Glazer, and W. C. Summers. 1987. Amplification and deregulation of MYC following Epstein-Barr virus infection of a human B-cell line. Proc. Natl. Acad. Sci. USA 84:5838.
25. Wang, F., C. Gregory, C. Sample, M. Rowe, D. Liebowitz, R. Murray, A. Rickinson, and E. Kieff. 1990. Epstein-Barr virus latent membrane protein (LMP1) and nuclear proteins 2 and 3C are effectors of phenotypic changes in B lymphocytes: EBNA-2 and LMP1 cooperatively induce CD23. J. Virol. 64:2309.
26. Li, Y. P., R. Tomanin, J. R. Smiley, and S. Bacchetti. 1993. Generation of a new adenovirus type 12-inducible fragile site by insertion of an artificial U2 locus in the human genome. Mol. Cell. Biol. 13:6064.
27. Dunnick, W., G. Z. Hertz, L. Scappino, and C. Gritzmacher. 1993. DNA sequences at immunoglobulin switch region recombination sites. Nucleic Acids Res. 21:365.
28. Lee, C. G., S. Kondo, and T. Honjo. 1998. Frequent but biased class switch recombination in the Sμ flanking regions. Curr. Biol. 8:227.
29. Maizels. 1999. Immunoglobulin class switch recombination: will genetics provide new clues to mechanism? Am. J. Hum. Genet. 64:1270.