Interaction of DNA Fragmentation Factor (DFF) with DNA reveals an unprecedented mechanism for nuclease inhibition and suggests that DFF can be activated in a DNA-bound state

Journal of Biological Chemistry

Volumn 280, Issue 7, 2005, Pages 6005-6015

  Korn, Christian ^a   Scholz, Sebastian R ^a   Gimadutdinow, Oleg ^b   Lurz, Rudi ^c   Pingoud, Alfred ^a   Meiss, Gregor ^a  

^a JUSTUS LIEBIG UNIVERSITY   (Germany)

^b KAZAN FEDERAL UNIVERSITY   (Russian Federation)

^c MAX PLANCK INSTITUTE FOR MOLECULAR GENETICS   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; BINDING ENERGY; CATALYSIS; CELLS; ENZYME INHIBITION; ENZYMES;

APOPTOSIS; DNA FRAGMENTATION; DNA FRAGMENTATION FACTORS (DFF); NUCLEASE;

DNA;

DNA; DNA FRAGMENT; DNA FRAGMENTATION FACTOR; NUCLEASE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CELL NUCLEUS; CHROMATIN; CONTROLLED STUDY; DNA BINDING; DNA CLEAVAGE; DNA DEGRADATION; ENZYME INHIBITION; ENZYME SUBUNIT; GENE EXPRESSION; GENETIC TRAIT; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION;

ANIMALS; APOPTOSIS; APOPTOSIS REGULATORY PROTEINS; BASE SEQUENCE; CASPASE 3; CASPASES; CHROMATIN; DEOXYRIBONUCLEASES; DNA; ENZYME ACTIVATION; HELA CELLS; HUMANS; MICE; MICROSCOPY, ELECTRON, TRANSMISSION; MODELS, BIOLOGICAL; MODELS, MOLECULAR; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN SUBUNITS; PROTEIN TRANSPORT; PROTEINS; RECOMBINANT PROTEINS; SUBSTRATE SPECIFICITY; TRANSFECTION;

EID: 14044274338     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M413035200     Document Type: Article

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