메뉴 건너뛰기




Volumn 288, Issue 3 57-3, 2005, Pages

Urinary trypsin inhibitor reduces LPS-induced hypotension by suppressing tumor necrosis factor-α production through inhibition of Egr-1 expression

Author keywords

Early growth response factor 1; Inducible nitric oxide synthase; Lipopolysaccharide; Septic shock

Indexed keywords

AMINOGUANIDINE; EARLY GROWTH RESPONSE FACTOR 1; ESCHERICHIA COLI LIPOPOLYSACCHARIDE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NITRATE; NITRITE; PROTEIN C FOS; SYNAPTOTAGMIN; TRANSCRIPTION FACTOR AP 1; TUMOR NECROSIS FACTOR ALPHA; ULINASTATIN;

EID: 13944266755     PISSN: 03636135     EISSN: None     Source Type: Journal    
DOI: 10.1152/ajpheart.00885.2004     Document Type: Article
Times cited : (38)

References (31)
  • 1
    • 0035259695 scopus 로고    scopus 로고
    • Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor α production of monocytes
    • Aosasa S, Ono S, Mochizuki H, Tsujimoto H, Ueno C, and Matsumoto A. Mechanism of the inhibitory effect of protease inhibitor on tumor necrosis factor α production of monocytes. Shock 15: 101-105, 2001.
    • (2001) Shock , vol.15 , pp. 101-105
    • Aosasa, S.1    Ono, S.2    Mochizuki, H.3    Tsujimoto, H.4    Ueno, C.5    Matsumoto, A.6
  • 2
    • 0027362533 scopus 로고
    • Pathophysiology of septic shock and implications for therapy
    • Barron RL. Pathophysiology of septic shock and implications for therapy. Clin Pharm 12: 829-845, 1993.
    • (1993) Clin Pharm , vol.12 , pp. 829-845
    • Barron, R.L.1
  • 3
    • 0033987191 scopus 로고    scopus 로고
    • Bikunin-not just a plasma proteinase inhibitor
    • Fries E and Blom AM. Bikunin-not just a plasma proteinase inhibitor. Int J Biochem Cell Biol 32: 125-137, 2000.
    • (2000) Int J Biochem Cell Biol , vol.32 , pp. 125-137
    • Fries, E.1    Blom, A.M.2
  • 4
    • 0035469890 scopus 로고    scopus 로고
    • Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression
    • Guha M, O'Connell MA, Pawlinski R, Hollis A, McGovern P, Yan SF, Stern D, and Mackman N. Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor α expression by inducing Elk-1 phosphorylation and Egr-1 expression. Blood 98: 1429-1439, 2001.
    • (2001) Blood , vol.98 , pp. 1429-1439
    • Guha, M.1    O'Connell, M.A.2    Pawlinski, R.3    Hollis, A.4    McGovern, P.5    Yan, S.F.6    Stern, D.7    Mackman, N.8
  • 5
    • 0029958946 scopus 로고    scopus 로고
    • Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide- stimulated macrophages
    • Hambleton J, Weinstein SL, Lem L, and DeFranco AL. Activation of c-Jun N-terminal kinase in bacterial lipopolysaccharide-stimulated macrophages. Proc Natl Acad Sci USA 93: 2774-2778, 1996.
    • (1996) Proc Natl Acad Sci USA , vol.93 , pp. 2774-2778
    • Hambleton, J.1    Weinstein, S.L.2    Lem, L.3    DeFranco, A.L.4
  • 6
    • 0031877808 scopus 로고    scopus 로고
    • Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins
    • Hirose J, Ozawa T, Miura T, Isaji M, Nagao Y, Yamashiro K, Nii A, Kato K, and Uemura A. Human neutrophil elastase degrades inter-alpha-trypsin inhibitor to liberate urinary trypsin inhibitor related proteins. Biol Pharm Bull 21: 651-656, 1998.
    • (1998) Biol Pharm Bull , vol.21 , pp. 651-656
    • Hirose, J.1    Ozawa, T.2    Miura, T.3    Isaji, M.4    Nagao, Y.5    Yamashiro, K.6    Nii, A.7    Kato, K.8    Uemura, A.9
  • 7
    • 0036493335 scopus 로고    scopus 로고
    • Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats
    • Isobe H, Okajima K, Uchiba M, Harada N, and Okabe H. Antithrombin prevents endotoxin-induced hypotension by inhibiting the induction of nitric oxide synthase in rats. Blood 99: 1638-1645, 2002.
    • (2002) Blood , vol.99 , pp. 1638-1645
    • Isobe, H.1    Okajima, K.2    Uchiba, M.3    Harada, N.4    Okabe, H.5
  • 8
    • 0035806897 scopus 로고    scopus 로고
    • Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide
    • Isobe H, Okajima K, Uchiba M, Mizutani A, Harada N, Nagasaki A, and Okabe H. Activated protein C prevents endotoxin-induced hypotension in rats by inhibiting excessive production of nitric oxide. Circulation 104: 1171-1175, 2001.
    • (2001) Circulation , vol.104 , pp. 1171-1175
    • Isobe, H.1    Okajima, K.2    Uchiba, M.3    Mizutani, A.4    Harada, N.5    Nagasaki, A.6    Okabe, H.7
  • 9
    • 0024791433 scopus 로고
    • Radioimmunological quantitation of the urinary trypsin inhibitor in normal blood and urine
    • Jönsson BM, Ohlsson K, and Rosengren M. Radioimmunological quantitation of the urinary trypsin inhibitor in normal blood and urine. Biol Chem 370: 1157-1161, 1989.
    • (1989) Biol Chem , vol.370 , pp. 1157-1161
    • Jönsson, B.M.1    Ohlsson, K.2    Rosengren, M.3
  • 12
    • 0031568533 scopus 로고    scopus 로고
    • Stimulation of macrophage by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU. 1 via activation of casein kinase II
    • Lodie TA, Savedra R, Golenbock DT, Van Beveren CP, Maki RA, and Fenton MJ. Stimulation of macrophage by lipopolysaccharide alters the phosphorylation state, conformation, and function of PU. 1 via activation of casein kinase II. J Immunol 158: 1848-1856, 1997.
    • (1997) J Immunol , vol.158 , pp. 1848-1856
    • Lodie, T.A.1    Savedra, R.2    Golenbock, D.T.3    Van Beveren, C.P.4    Maki, R.A.5    Fenton, M.J.6
  • 13
    • 0030060762 scopus 로고    scopus 로고
    • The effects of ulinastatin, a human protease inhibitor, on the transfusion-induced increase of plasma polymolphonuclear granulocyte elastase
    • Nishiyama T, Aibiki M, and Hanaoka K. The effects of ulinastatin, a human protease inhibitor, on the transfusion-induced increase of plasma polymolphonuclear granulocyte elastase. Anesth Analg 82: 108-112, 1996.
    • (1996) Anesth Analg , vol.82 , pp. 108-112
    • Nishiyama, T.1    Aibiki, M.2    Hanaoka, K.3
  • 14
    • 0021332228 scopus 로고
    • Effects of urinary trypsin inhibitor on pancreatic enzyme and experimental acute pancreatitis
    • Ohnishi H, Kosuzume H, Ashida Y, Kato K, and Honjo I. Effects of urinary trypsin inhibitor on pancreatic enzyme and experimental acute pancreatitis. Dig Dis Sci 29: 26-32, 1984.
    • (1984) Dig Dis Sci , vol.29 , pp. 26-32
    • Ohnishi, H.1    Kosuzume, H.2    Ashida, Y.3    Kato, K.4    Honjo, I.5
  • 15
    • 0027487144 scopus 로고
    • Increase in the plasma concentration of reduced glutathione observed in rats with liver damage induced by lipopolysaccharide/D-galactosamine: Effects of ulinastatin, a urinary trypsin inhibitor
    • Okabe H, Irita K, Kurosawa K, Tagawa K, Koga A, Yamakawa M, Yoshitaka J, and Takahashi S. Increase in the plasma concentration of reduced glutathione observed in rats with liver damage induced by lipopolysaccharide/D- galactosamine: effects of ulinastatin, a urinary trypsin inhibitor. Circ Shock 41: 268-272, 1993.
    • (1993) Circ Shock , vol.41 , pp. 268-272
    • Okabe, H.1    Irita, K.2    Kurosawa, K.3    Tagawa, K.4    Koga, A.5    Yamakawa, M.6    Yoshitaka, J.7    Takahashi, S.8
  • 16
    • 0035707639 scopus 로고    scopus 로고
    • Regulation of inflammatory responses by natural anticoagulants
    • Okajima K. Regulation of inflammatory responses by natural anticoagulants. Immunol Rev 184: 258-274, 2001.
    • (2001) Immunol Rev , vol.184 , pp. 258-274
    • Okajima, K.1
  • 17
    • 1642456792 scopus 로고    scopus 로고
    • Microthrombus formation enhances tumor necrosis factor-alpha production in the development of ischemia/reperfusion-induced liver injury in rats
    • Okajima K, Harada N, and Uchiba M. Microthrombus formation enhances tumor necrosis factor-alpha production in the development of ischemia/reperfusion- induced liver injury in rats. J Thromb Haemost 1: 1316-1317, 2003.
    • (2003) J Thromb Haemost , vol.1 , pp. 1316-1317
    • Okajima, K.1    Harada, N.2    Uchiba, M.3
  • 18
    • 0028491901 scopus 로고
    • A therapeutic effect of ulinastatin on endotoxin-induced shock in dogs-comparison with methylprednisolone
    • Okano S, Tagawa M, Urakawa N, and Ogawa R. A therapeutic effect of ulinastatin on endotoxin-induced shock in dogs-comparison with methylprednisolone. J Vet Med Sci 56: 645-649, 1994.
    • (1994) J Vet Med Sci , vol.56 , pp. 645-649
    • Okano, S.1    Tagawa, M.2    Urakawa, N.3    Ogawa, R.4
  • 19
    • 0027920980 scopus 로고
    • Pathogenetic mechanisms of septic shock
    • Parrillo JE. Pathogenetic mechanisms of septic shock. N Engl J Med 328: 1471-1477, 1993.
    • (1993) N Engl J Med , vol.328 , pp. 1471-1477
    • Parrillo, J.E.1
  • 20
    • 0034146430 scopus 로고    scopus 로고
    • Interactions of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNF-α production
    • Rosengart MR, Arbabi S, Garcia I, and Maier RV. Interactions of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular-regulated kinase (ERK) in monocyte adherence and TNF-α production. Shock 13: 183-189, 2000.
    • (2000) Shock , vol.13 , pp. 183-189
    • Rosengart, M.R.1    Arbabi, S.2    Garcia, I.3    Maier, R.V.4
  • 21
    • 0034219017 scopus 로고    scopus 로고
    • Induction of acute-phase reactive substances during open-heart surgery and efficacy of ulinastatin. Inhibiting cytokines and postoperative organ injury
    • Sato Y, Ishikawa S, Otaki A, Takahashi T, Hasegawa Y, Suzuki M, Yamagishi T, and Morishita Y. Induction of acute-phase reactive substances during open-heart surgery and efficacy of ulinastatin. Inhibiting cytokines and postoperative organ injury. Jpn J Thorac Cardiovasc Surg 48: 428-434, 2000.
    • (2000) Jpn J Thorac Cardiovasc Surg , vol.48 , pp. 428-434
    • Sato, Y.1    Ishikawa, S.2    Otaki, A.3    Takahashi, T.4    Hasegawa, Y.5    Suzuki, M.6    Yamagishi, T.7    Morishita, Y.8
  • 22
    • 0036083377 scopus 로고    scopus 로고
    • Lipopolysaccharide stimulation of ERK1/2 increases TNF-α production-via Egr-1
    • Shi L, Kishore R, McMullen MR, and Nagy LE. Lipopolysaccharide stimulation of ERK1/2 increases TNF-α production-via Egr-1. Am J Physiol Cell Physiol 282: C1205-C1211, 2002.
    • (2002) Am J Physiol Cell Physiol , vol.282
    • Shi, L.1    Kishore, R.2    McMullen, M.R.3    Nagy, L.E.4
  • 23
    • 0027476883 scopus 로고
    • Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock
    • Szabo Mitchell JA, Thiemermann C, and Vane JR. Nitric oxide-mediated hyporeactivity to noradrenaline precedes the induction of nitric oxide synthase in endotoxin shock. Br J Pharmacol 108: 786-792, 1993.
    • (1993) Br J Pharmacol , vol.108 , pp. 786-792
    • Szabo Mitchell, J.A.1    Thiemermann, C.2    Vane, J.R.3
  • 24
    • 0027312522 scopus 로고
    • Treatment of septic shock with a protease inhibitor in a canine model: A prospective, randomized, controlled trial
    • Tani T, Aoki H, Yoshioka T, Lin KJ, and Kodama M. Treatment of septic shock with a protease inhibitor in a canine model: a prospective, randomized, controlled trial. Crit Care Med 21: 925-930, 1993.
    • (1993) Crit Care Med , vol.21 , pp. 925-930
    • Tani, T.1    Aoki, H.2    Yoshioka, T.3    Lin, K.J.4    Kodama, M.5
  • 25
    • 0027237013 scopus 로고
    • Role of tumor necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock
    • Thiemermann C, Wu CC, Szabo C, Perretti M, and Vane JR. Role of tumor necrosis factor in the induction of nitric oxide synthase in a rat model of endotoxin shock. Br J Pharmacol 110: 177-182, 1993.
    • (1993) Br J Pharmacol , vol.110 , pp. 177-182
    • Thiemermann, C.1    Wu, C.C.2    Szabo, C.3    Perretti, M.4    Vane, J.R.5
  • 26
    • 0031045815 scopus 로고    scopus 로고
    • Effect of nafamostat mesilate on pulmonary vascular injury induced by lipopolysaccharide in rats
    • Uchiba M, Okajima K, Murakami K, Okabe H, and Takatsuki K. Effect of nafamostat mesilate on pulmonary vascular injury induced by lipopolysaccharide in rats. Am J Respir Crit Care Med 155: 711-718, 1997.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 711-718
    • Uchiba, M.1    Okajima, K.2    Murakami, K.3    Okabe, H.4    Takatsuki, K.5
  • 27
    • 0027507239 scopus 로고
    • Neutrophil-mediated damage to human vascular endothelium. Role of cytokine activation
    • Westlin WF and Gimbrone MA Jr. Neutrophil-mediated damage to human vascular endothelium. Role of cytokine activation. Am J Pathol 142: 117-128, 1993.
    • (1993) Am J Pathol , vol.142 , pp. 117-128
    • Westlin, W.F.1    Gimbrone Jr., M.A.2
  • 29
    • 0036189589 scopus 로고    scopus 로고
    • Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis
    • Yang S, Lim YP, Zhou M, Salvemini P, Schwinn H, Josic D, Koo DJ, Chaudry IH, and Wang P. Administration of human inter-alpha-inhibitors maintains hemodynamic stability and improves survival during sepsis. Crit Care Med 30: 617-622, 2002.
    • (2002) Crit Care Med , vol.30 , pp. 617-622
    • Yang, S.1    Lim, Y.P.2    Zhou, M.3    Salvemini, P.4    Schwinn, H.5    Josic, D.6    Koo, D.J.7    Chaudry, I.H.8    Wang, P.9
  • 30
    • 0030858764 scopus 로고    scopus 로고
    • Lypopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells: Regulation by Egr-1, c-Jun and NF-κB transcription factors
    • Yao J, Mackman N, Edgington TS, and Fan ST. Lypopolysaccharide induction of the tumor necrosis factor-α promoter in human monocytic cells: regulation by Egr-1, c-Jun and NF-κB transcription factors. J Biol Chem 272: 17795-17801, 1997.
    • (1997) J Biol Chem , vol.272 , pp. 17795-17801
    • Yao, J.1    Mackman, N.2    Edgington, T.S.3    Fan, S.T.4
  • 31
    • 0037381555 scopus 로고    scopus 로고
    • Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-α production by inhibiting activation of both nuclear factor-κB and activator protein-1 in human monocytes
    • Yuksel M, Okajima K, Uchiba M, and Okabe H. Gabexate mesilate, a synthetic protease inhibitor, inhibits lipopolysaccharide-induced tumor necrosis factor-α production by inhibiting activation of both nuclear factor-κB and activator protein-1 in human monocytes. J Pharmacol Exp Ther 305: 298-305, 2003.
    • (2003) J Pharmacol Exp Ther , vol.305 , pp. 298-305
    • Yuksel, M.1    Okajima, K.2    Uchiba, M.3    Okabe, H.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.